Identification of Liver Cancer Progenitors Whose Malignant Progression Depends on Autocrine IL-6 Signaling von He, Guobin, Dhar, Debanjan, Nakagawa, Hayato, Font-Burgada, Joan, Ogata, Hisanobu, Jiang, Yuhong, Shalapour, Shabnam, Seki, Ekihiro, Yost, Shawn E., Jepsen, Kristen, Frazer, Kelly A., Harismendy, Olivier, Hatziapostolou, Maria, Iliopoulos, Dimitrios, Suetsugu, Atsushi, Hoffman, Robert M., Tateishi, Ryosuke, Koike, Kazuhiko, Karin, Michael

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Human genetic variation and its contribution to complex traits von Frazer, Kelly A, Murray, Sarah S, Schork, Nicholas J, Topol, Eric J

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Cellular deconvolution of GTEx tissues powers discovery of disease and cell-type associated regulatory variants von Donovan, Margaret K. R., D’Antonio-Chronowska, Agnieszka, D’Antonio, Matteo, Frazer, Kelly A.

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Subtle changes in chromatin loop contact propensity are associated with differential gene regulation and expression von Greenwald, William W., Li, He, Benaglio, Paola, Jakubosky, David, Matsui, Hiroko, Schmitt, Anthony, Selvaraj, Siddarth, D’Antonio, Matteo, D’Antonio-Chronowska, Agnieszka, Smith, Erin N., Frazer, Kelly A.

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Transcriptome sequencing reveals potential mechanism of cryptic 3' splice site selection in SF3B1-mutated cancers von DeBoever, Christopher, Ghia, Emanuela M, Shepard, Peter J, Rassenti, Laura, Barrett, Christian L, Jepsen, Kristen, Jamieson, Catriona H M, Carson, Dennis, Kipps, Thomas J, Frazer, Kelly A

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ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis von Zipeto, Maria Anna, Court, Angela C., Sadarangani, Anil, Delos Santos, Nathaniel P., Balaian, Larisa, Chun, Hye-Jung, Pineda, Gabriel, Morris, Sheldon R., Mason, Cayla N., Geron, Ifat, Barrett, Christian, Goff, Daniel J., Wall, Russell, Pellecchia, Maurizio, Minden, Mark, Frazer, Kelly A., Marra, Marco A., Crews, Leslie A., Jiang, Qingfei, Jamieson, Catriona H.M.

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Large-Scale Profiling Reveals the Influence of Genetic Variation on Gene Expression in Human Induced Pluripotent Stem Cells von DeBoever, Christopher, Li, He, Jakubosky, David, Benaglio, Paola, Reyna, Joaquin, Olson, Katrina M., Huang, Hui, Biggs, William, Sandoval, Efren, D’Antonio, Matteo, Jepsen, Kristen, Matsui, Hiroko, Arias, Angelo, Ren, Bing, Nariai, Naoki, Smith, Erin N., D’Antonio-Chronowska, Agnieszka, Farley, Emma K., Frazer, Kelly A.

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miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1 von Mraz, Marek, Chen, Liguang, Rassenti, Laura Z., Ghia, Emanuela M., Li, Hongying, Jepsen, Kristen, Smith, Erin N., Messer, Karen, Frazer, Kelly A., Kipps, Thomas J.

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PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3 von Benitez, Jorge A., Ma, Jianhui, D’Antonio, Matteo, Boyer, Antonia, Camargo, Maria Fernanda, Zanca, Ciro, Kelly, Stephen, Khodadadi-Jamayran, Alireza, Jameson, Nathan M., Andersen, Michael, Miletic, Hrvoje, Saberi, Shahram, Frazer, Kelly A., Cavenee, Webster K., Furnari, Frank B.

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Evaluation of next generation sequencing platforms for population targeted sequencing studies von Harismendy, Olivier, Ng, Pauline C, Strausberg, Robert L, Wang, Xiaoyun, Stockwell, Timothy B, Beeson, Karen Y, Schork, Nicholas J, Murray, Sarah S, Topol, Eric J, Levy, Samuel, Frazer, Kelly A

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High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer von Schmidt, Tobias T., Tyer, Carly, Rughani, Preeyesh, Haggblom, Candy, Jones, Jeffrey R., Dai, Xiaoguang, Frazer, Kelly A., Gage, Fred H., Juul, Sissel, Hickey, Scott, Karlseder, Jan

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In heart failure reactivation of RNA-binding proteins is associated with the expression of 1,523 fetal-specific isoforms von D'Antonio, Matteo, Nguyen, Jennifer P, Arthur, Timothy D, Matsui, Hiroko, Donovan, Margaret K R, D'Antonio-Chronowska, Agnieszka, Frazer, Kelly A

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Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk von Greenwald, William W., Chiou, Joshua, Yan, Jian, Qiu, Yunjiang, Dai, Ning, Wang, Allen, Nariai, Naoki, Aylward, Anthony, Han, Jee Yun, Kadakia, Nikita, Regue, Laura, Okino, Mei-Lin, Drees, Frauke, Kramer, Dana, Vinckier, Nicholas, Minichiello, Liliana, Gorkin, David, Avruch, Joseph, Frazer, Kelly A., Sander, Maike, Ren, Bing, Gaulton, Kyle J.

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Kataegis Expression Signature in Breast Cancer Is Associated with Late Onset, Better Prognosis, and Higher HER2 Levels von D’Antonio, Matteo, Tamayo, Pablo, Mesirov, Jill P., Frazer, Kelly A.

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Whole-Genome Sequencing Uncovers the Genetic Basis of Chronic Mountain Sickness in Andean Highlanders von Zhou, Dan, Udpa, Nitin, Ronen, Roy, Stobdan, Tsering, Liang, Junbin, Appenzeller, Otto, Zhao, Huiwen W., Yin, Yi, Du, Yuanping, Guo, Lixia, Cao, Rui, Wang, Yu, Jin, Xin, Huang, Chen, Jia, Wenlong, Cao, Dandan, Guo, Guangwu, Gamboa, Jorge L., Villafuerte, Francisco, Callacondo, David, Xue, Jin, Liu, Siqi, Frazer, Kelly A., Li, Yingrui, Bafna, Vineet, Haddad, Gabriel G.

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Whole-Genome Patterns of Common DNA Variation in Three Human Populations von Hinds, David A., Stuve, Laura L., Nilsen, Geoffrey B., Halperin, Eran, Eskin, Eleazar, Ballinger, Dennis G., Frazer, Kelly A., Cox, David R.

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Genomewide SNP Variation Reveals Relationships among Landraces and Modern Varieties of Rice von McNally, Kenneth L., Childs, Kevin L., Bohnert, Regina, Davidson, Rebecca M., Zhao, Keyan, Ulat, Victor J., Zeller, Georg, Clark, Richard M., Hoen, Douglas R., Bureau, Thomas E., Stokowski, Renee, Ballinger, Dennis G., Frazer, Kelly A., Cox, David R., Padhukasahasram, Badri, Bustamante, Carlos D., Weigel, Detlef, Mackill, David J., Bruskiewich, Richard M., Rätsch, Gunnar, Buell, C. Robin, Leung, Hei, Leach, Jan E., Phillips, Ronald L.

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Systematic transcriptome analysis reveals tumor-specific isoforms for ovarian cancer diagnosis and therapy von Barrett, Christian L., DeBoever, Christopher, Jepsen, Kristen, Saenz, Cheryl C., Carson, Dennis A., Frazer, Kelly A.

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High-Resolution Whole-Genome Association Study of Parkinson Disease von Maraganore, Demetrius M., de Andrade, Mariza, Lesnick, Timothy G., Strain, Kari J., Farrer, Matthew J., Rocca, Walter A., Pant, P.V. Krishna, Frazer, Kelly A., Cox, David R., Ballinger, Dennis G.

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ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia von Jiang, Qingfei, Crews, Leslie A., Barrett, Christian L., Chun, Hye-Jung, Court, Angela C., Isquith, Jane M., Zipeto, Maria A., Goff, Daniel J., Minden, Mark, Sadarangani, Anil, Rusert, Jessica M., Dao, Kim-Hien T., Morris, Sheldon R., Goldstein, Lawrence S. B., Marra, Marco A., Frazer, Kelly A., Jamieson, Catriona H. M.

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