NF-κB Signaling in Macrophages: Dynamics, Crosstalk, and Signal Integration von Dorrington, Michael G, Fraser, Iain D C

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Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection von Grainger, John R, Wohlfert, Elizabeth A, Fuss, Ivan J, Bouladoux, Nicolas, Askenase, Michael H, Legrand, Fanny, Koo, Lily Y, Brenchley, Jason M, Fraser, Iain D C, Belkaid, Yasmine

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Identification of age-specific gene regulators of La Crosse virus neuroinvasion and pathogenesis von Basu, Rahul, Ganesan, Sundar, Winkler, Clayton W., Anzick, Sarah L., Martens, Craig, Peterson, Karin E., Fraser, Iain D. C.

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Bactericidal antibiotic treatment induces damaging inflammation via TLR9 sensing of bacterial DNA von Gross, Julia L., Basu, Rahul, Bradfield, Clinton J., Sun, Jing, John, Sinu P., Das, Sanchita, Dekker, John P., Weiss, David S., Fraser, Iain D. C.

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U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies von Smith, Molly A., Choudhary, Gaurav S., Pellagatti, Andrea, Choi, Kwangmin, Bolanos, Lyndsey C., Bhagat, Tushar D., Gordon-Mitchell, Shanisha, Von Ahrens, Dagny, Pradhan, Kith, Steeples, Violetta, Kim, Sanghyun, Steidl, Ulrich, Walter, Matthew, Fraser, Iain D. C., Kulkarni, Aishwarya, Salomonis, Nathan, Komurov, Kakajan, Boultwood, Jacqueline, Verma, Amit, Starczynowski, Daniel T.

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The ontogeny of cerebrovascular pressure autoregulation in premature infants von Rhee, C J, Fraser III, C D, Kibler, K, Easley, R B, Andropoulos, D B, Czosnyka, M, Varsos, G V, Smielewski, P, Rusin, C G, Brady, K M, Kaiser, J R

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Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol von Dorrington, Michael G, Bradfield, Clinton J, Lack, Justin B, Lin, Bin, Liang, Jonathan J, Starr, Tregei, Ernst, Orna, Gross, Julia L, Sun, Jing, Miller, Alexandra H, Steele-Mortimer, Olivia, Fraser, Iain D C

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Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88 von Sakai, Jiro, Cammarota, Eugenia, Wright, John A., Cicuta, Pietro, Gottschalk, Rachel A., Li, Ning, Fraser, Iain D. C., Bryant, Clare E.

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A Single Lentiviral Vector Platform for MicroRNA-Based Conditional RNA Interference and Coordinated Transgene Expression von Shin, Kum-Joo, Wall, Estelle A., Zavzavadjian, Joelle R., Santat, Leah A., Liu, Jamie, Hwang, Jong-lk, Rebres, Robert, Roach, Tamara, Seaman, William, Simon, Melvin I., Fraser, Iain D. C.

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Correction: Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol von Dorrington, Michael G, Bradfield, Clinton J, Lack, Justin B, Lin, Bin, John, Sinu P, Liang, Jonathan J, Starr, Tregei, Ernst, Orna, Gross, Julia L, Sun, Jing, Miller, Alexandra H, Steele-Mortimer, Olivia, Fraser, Iain D. C

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Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways von Manes, Nathan P., Calzola, Jessica M., Kaplan, Pauline R., Fraser, Iain D. C., Germain, Ronald N., Meier-Schellersheim, Martin, Nita-Lazar, Aleksandra

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Regulation of NMDA Receptors by an Associated Phosphatase-Kinase Signaling Complex von Westphal, Ryan S., Tavalin, Steven J., Lin, Jerry W., Alto, Neal M., Lain D. C. Fraser, Langeberg, Lorene K., Sheng, Morgan, Scott, John D.

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Lipid regulation of NLRP3 inflammasome activity through organelle stress von Liang, Jonathan J., Fraser, Iain D.C., Bryant, Clare E.

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Species-Specific Endotoxin Stimulus Determines Toll-Like Receptor 4- and Caspase 11-Mediated Pathway Activation Characteristics von Ernst, Orna, Khan, Mohd M, Oyler, Benjamin L, Yoon, Sung Hwan, Sun, Jing, Lin, Fang-Yu, Manes, Nathan P, MacKerell, Jr, Alexander D, Fraser, Iain D C, Ernst, Robert K, Goodlett, David R, Nita-Lazar, Aleksandra

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Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action von Oh, Kyu-Seon, Patel, Heta, Gottschalk, Rachel A., Lee, Wai Shing, Baek, Songjoon, Fraser, Iain D.C., Hager, Gordon L., Sung, Myong-Hee

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Biphasic JNK signaling reveals distinct MAP3K complexes licensing inflammasome formation and pyroptosis von Bradfield, Clinton J., Liang, Jonathan J., Ernst, Orna, John, Sinu P., Sun, Jing, Ganesan, Sundar, de Jesus, Adriana A., Bryant, Clare E., Goldbach-Mansky, Raphaela, Fraser, Iain D. C.

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Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use von Sun, Jing, Li, Ning, Oh, Kyu-Seon, Dutta, Bhaskar, Vayttaden, Sharat J, Lin, Bin, Ebert, Thomas S, De Nardo, Dominic, Davis, Joie, Bagirzadeh, Rustam, Lounsbury, Nicolas W, Pasare, Chandrashekhar, Latz, Eicke, Hornung, Veit, Fraser, Iain D C

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Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons von Welsbie, Derek S., Mitchell, Katherine L., Jaskula-Ranga, Vinod, Sluch, Valentin M., Yang, Zhiyong, Kim, Jessica, Buehler, Eugen, Patel, Amit, Martin, Scott E., Zhang, Ping-Wu, Ge, Yan, Duan, Yukan, Fuller, John, Kim, Byung-Jin, Hamed, Eman, Chamling, Xitiz, Lei, Lei, Fraser, Iain D.C., Ronai, Ze’ev A., Berlinicke, Cynthia A., Zack, Donald J.

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Age influences susceptibility of brain capillary endothelial cells to La Crosse virus infection and cell death von Basu, Rahul, Nair, Vinod, Winkler, Clayton W, Woods, Tyson A, Fraser, Iain D C, Peterson, Karin E

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The cAMP Pathway Amplifies Early MyD88-Dependent and Type I Interferon-Independent LPS-Induced Interleukin-10 Expression in Mouse Macrophages von Zor, Tsaffrir, Levy-Rimler, Galit, Ben-Arosh, Hadar, Ben-Dror, Iris, Athamna, Muhammad, Glucksam-Galnoy, Yifat, Ernst, Orna, Fraser, Iain D. C.

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