Surprising impact of stromal TIL’s on immunotherapy efficacy in a real-world lung cancer study von Hashemi, S., Fransen, M.F., Niemeijer, A., Ben Taleb, N., Houda, I., Veltman, J., Becker- Commissaris, A., Daniels, H., Crombag, L., Radonic, T., Jongeneel, G., Tarasevych, S., Looysen, E., van Laren, M., Tiemessen, M., van Diepen, V., Maassen-van den Brink, K., Thunnissen, E., Bahce, I.

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Longevity of Antigen Presentation and Activation Status of APC Are Decisive Factors in the Balance Between CTL Immunity Versus Tolerance von Th. den Boer, Annemieke, Diehl, Linda, van Mierlo, Geertje J. D, van der Voort, Ellen I. H, Fransen, Marieke F, Krimpenfort, Paul, Melief, Cornelis J. M, Offringa, Rienk, Toes, Rene E. M

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Intraocular Tumor Antigen Drains Specifically to Submandibular Lymph Nodes, Resulting in an Abortive Cytotoxic T Cell Reaction von Boonman, Zita F. H. M, van Mierlo, Geertje J. D, Fransen, Marieke F, Franken, Kees L. M. C, Offringa, Rienk, Melief, Cornelis J. M, Jager, Martine J, Toes, Rene E. M

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A Restricted Role for FcgammaR in the Regulation of Adaptive Immunity von Fransen, M. F., Benonisson, H., van Maren, W. W., Sow, H. S., Breukel, C., Linssen, M. M., Claassens, J. W. C., Brouwers, C., van der Kaa, J., Camps, M., Kleinovink, J. W., Vonk, K. K., van Heiningen, S., Klar, N., van Beek, L., van Harmelen, V., Daxinger, L., Nandakumar, Kutty Selva, Holmdahl, R., Coward, C., Lin, Q., Hirose, S., Salvatori, D., van Hall, T., van Kooten, C., Mastroeni, P., Ossendorp, F., Verbeek, J. S.

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Activation of Dendritic Cells That Cross-Present Tumor-Derived Antigen Licenses CD8+ CTL to Cause Tumor Eradication von van Mierlo, Geertje J. D, Boonman, Zita F. H. M, Dumortier, Helene M. H, den Boer, Annemieke Th, Fransen, Marieke F, Nouta, Jan, van der Voort, Ellen I. H, Offringa, Rienk, Toes, Rene E. M, Melief, Cornelis J. M

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CD40 Stimulation Leads to Effective Therapy of CD40- Tumors through Induction of Strong Systemic Cytotoxic T Lymphocyte Immunity von Geertje J. D. van Mierlo, Annemieke Th. den Boer, Medema, Jan Paul, Ellen I. H. van der Voort, Fransen, Marieke F., Offringa, Rienk, Cornelis J. M. Melief, Rene E. M. Toes

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CD4+ T cells are able to promote tumor growth through inhibition of tumor-specific CD8+ T-cell responses in tumor-bearing hosts von DEN BOER, Annemieke Th, VAN MIERLO, Geertje J. D, FRANSEN, Marieke F, MELIEF, Cornelis J. M, OFFRINGA, Rienk, TOES, René E. M

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The Tumoricidal Activity of Memory CD8+ T Cells Is Hampered by Persistent Systemic Antigen, but Full Functional Capacity Is Regained in an Antigen-Free Environment von den Boer, Annemieke Th, van Mierlo, Geertje J. D, Fransen, Marieke F, Melief, Cornelis J. M, Offringa, Rienk, Toes, Rene E. M

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Maintenance of Immune Tolerance Depends on Normal Tissue Homeostasis von Boonman, Zita F. H. M, van Mierlo, Geertje J. D, Fransen, Marieke F, de Keizer, Rob J. W, Jager, Martine J, Melief, Cornelis J. M, Toes, Rene E. M

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CD40 stimulation leads to effective therapy of CD40 super(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity von van Mierlo, GJD, den Boer, AT, Medema, J P, van der Voort, EIH, Fransen, M F, Offringa, R, Melief, CJM, Toes, REM

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Global Groundwater Modeling and Monitoring: Opportunities and Challenges von Condon, Laura E., Kollet, Stefan, Bierkens, Marc F. P., Fogg, Graham E., Maxwell, Reed M., Hill, Mary C., Fransen, Harrie‐Jan Hendricks, Verhoef, Anne, Van Loon, Anne F., Sulis, Mauro, Abesser, Corinna

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Two-Year Outcome after Endovascular Treatment for Acute Ischemic Stroke von van den Berg, Lucie A, Dijkgraaf, Marcel G.W, Berkhemer, Olvert A, Fransen, Puck S.S, Beumer, Debbie, Lingsma, Hester F, Majoie, Charles B.L.M, Dippel, Diederik W.J, van der Lugt, Aad, van Oostenbrugge, Robert J, van Zwam, Wim H, Roos, Yvo B.W.E.M

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A dynamic path planning approach for dense, large, grid-based automated guided vehicle systems von Fransen, K.J.C., van Eekelen, J.A.W.M., Pogromsky, A., Boon, M.A.A., Adan, I.J.B.F.

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Direct Oral Feeding Following Minimally Invasive Esophagectomy (NUTRIENT II trial): An International, Multicenter, Open-label Randomized Controlled Trial von Berkelmans, Gijs H. K., Fransen, Laura F. C., Dolmans-Zwartjes, Annemarie C. P., Kouwenhoven, Ewout A., van Det, Marc J., Nilsson, Magnus, Nieuwenhuijzen, Grard A. P., Luyer, Misha D. P.

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Effect of baseline Alberta Stroke Program Early CT Score on safety and efficacy of intra-arterial treatment: a subgroup analysis of a randomised phase 3 trial (MR CLEAN) von Yoo, Albert J, Dr, Berkhemer, Olvert A, MD, Fransen, Puck S S, MD, van den Berg, Lucie A, MD, Beumer, Debbie, MD, Lingsma, Hester F, PhD, Schonewille, Wouter J, MD, Sprengers, Marieke E S, MD, van den Berg, René, MD, van Walderveen, Marianne A A, MD, Beenen, Ludo F M, MD, Wermer, Marieke J H, MD, Nijeholt, Geert J Lycklama à, MD, Boiten, Jelis, MD, Jenniskens, Sjoerd F M, MD, Bot, Joseph C J, MD, Boers, Anna M M, MSc, Marquering, Henk A, PhD, Roos, Yvo B W E M, Prof, van Oostenbrugge, Robert J, Prof, Dippel, Diederik W J, Prof, van der Lugt, Aad, Prof, van Zwam, Wim H, MD, Majoie, Charles B L M, Prof

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Immunotherapy Goes Local: The Central Role of Lymph Nodes in Driving Tumor Infiltration and Efficacy von van Pul, Kim M, Fransen, Marieke F, van de Ven, Rieneke, de Gruijl, Tanja D

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Clinical Validation of the cobas 4800 HPV Test for Cervical Screening Purposes von HEIDEMAN, D. A. M, HESSELINK, A. T, BERKHOF, J, VAN KEMENADE, F, MELCHERS, W. J. G, FRANSEN DAALMEIJER, N, VERKUIJTEN, M, MEIJER, C. J. L. M, SNIJDERS, P. J. F

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Acute postoperative pain following hospital discharge after total knee arthroplasty von Chan, E.Y, Blyth, F.M, Nairn, L, Fransen, M

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MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial von Fransen, Puck S S, Beumer, Debbie, Berkhemer, Olvert A, van den Berg, Lucie A, Lingsma, Hester, van der Lugt, Aad, van Zwam, Wim H, van Oostenbrugge, Robert J, Roos, Yvo B W E M, Majoie, Charles B, Dippel, Diederik W J

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The Effect of Postoperative Complications After Minimally Invasive Esophagectomy on Long-term Survival: An International Multicenter Cohort Study von Fransen, Laura F. C., Berkelmans, Gijs H. K., Asti, Emanuele, Henegouwen, Mark I. van Berge, Berlth, Felix, Bonavina, Luigi, Brown, Andrew, Bruns, Christiane, van Daele, Elke, Gisbertz, Suzanne S., Grimminger, Peter P., Gutschow, Christian A., Hannink, Gerjon, Hölscher, Arnulf H., Kauppi, Juha, Lagarde, Sjoerd M., Mercer, Stuart, Moons, Johnny, Nafteux, Philippe, Nilsson, Magnus, Palazzo, Francesco, Pattyn, Piet, Raptis, Dimitri A., Räsanen, Jari, Rosato, Ernest L., Rouvelas, Ioannis, Schmidt, Henner M., Schneider, Paul M., Schröder, Wolfgang, van der Sluis, Pieter C., Wijnhoven, Bas P. L., Nieuwenhuijzen, Grard A. P., Luyer, Misha D. P.

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