The P2X3 receptor antagonist filapixant in patients with refractory chronic cough: a randomized controlled trial von Friedrich, Christian, Francke, Klaus, Birring, Surinder S, van den Berg, Jan Willem K, Marsden, Paul A, McGarvey, Lorcan, Turner, Alice M, Wielders, Pascal, Gashaw, Isabella, Klein, Stefan, Morice, Alyn H

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Pilocarpine‐Induced Effects on Salivary Secretion as a Pharmacological Biomarker for Cholinergic Parasympathetic Activation von Treijtel, Nicoline, Groenendaal‐van de Meent, Dorien, Michon, Ingrid, Korstanje, Cees, Meijer, John, Francke, Klaus, Grossmann, Matthias, Vries, Michiel

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Plasma-enhanced HC-SCR of NOx in the presence of excess oxygen von Miessner, Hans, Francke, Klaus-Peter, Rudolph, Rolf

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Effect Of A Novel, Oral Histamine H4R Antagonist On Histamine-Induced Pruritus In Healthy Subjects von Kollmeier, Alexa P., Dr, Dunford, Paul, MSc, Xu, Xie, PhD, Greenspan, Andrew, MD, Xia, Yichuan, PhD, Zhou, Bei, PhD, Francke, Klaus, MD, PhD, Thurmond, Robin L., Dr

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Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study von Morice, Alyn, Smith, Jaclyn A, McGarvey, Lorcan, Birring, Surinder S, Parker, Sean M, Turner, Alice, Hummel, Thomas, Gashaw, Isabella, Fels, Lueder, Klein, Stefan, Francke, Klaus, Friedrich, Christian

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P2X3 Receptor Antagonist Eliapixant in Phase I Clinical Trials: Safety and Inter-ethnic Comparison of Pharmacokinetics in Healthy Chinese and Japanese Participants von Li, Xuening, Haranaka, Miwa, Li, Hui, Liu, Pei, Chen, Huijun, Klein, Stefan, Reif, Stefanie, Francke, Klaus, Friedrich, Christian, Okumura, Kazuhito

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Pharmacodynamics, pharmacokinetics and CYP3A4 interaction potential of the selective P2X3 receptor antagonist filapixant: A randomized multiple ascending‐dose study in healthy youn... von Friedrich, Christian, Singh, Dave, Francke, Klaus, Klein, Stefan, Hetzel, Terence, Zolk, Oliver, Gashaw, Isabella, Scheerans, Christian, Morice, Alyn

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Safety, Pharmacodynamics, and Pharmacokinetics of P2X3 Receptor Antagonist Eliapixant (BAY 1817080) in Healthy Subjects: Double-Blind Randomized Study von Friedrich, Christian, Francke, Klaus, Gashaw, Isabella, Scheerans, Christian, Klein, Stefan, Fels, Lueder, Smith, Jaclyn A., Hummel, Thomas, Morice, Alyn

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Assessment of the CYP3A4 Induction Potential by Carbamazepine: Insights from Two Clinical DDI Studies and PBPK Modeling von Kanefendt, Friederike, Dallmann, André, Chen, Huijun, Francke, Klaus, Liu, Tianxing, Brase, Christine, Frechen, Sebastian, Schultze‐Mosgau, Marcus‐Hillert

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Preclinical and Clinical Pharmacokinetics and Bioavailability in Healthy Volunteers of a Novel Formulation of the Selective P2X3 Receptor Antagonist Eliapixant von Francke, Klaus, Chattopadhyay, Niladri, Klein, Stefan, Rottmann, Antje, Krickau, Dennis, van de Wetering, Jeroen, Friedrich, Christian

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Mass Balance Recovery, Absorption, Metabolism, and Excretion of Elinzanetant in Healthy Human Volunteers and in vitro Biotransformation: Mass balance recovery, absorption, metaboli... von Schulz, Simone I., Schultze-Mosgau, Marcus-Hillert, Engelen, Anna, Singh, Nand, Pawsey, Steve, Francke, Klaus, Lock, Ruth, Rottmann, Antje

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The Histamine H4 Receptor Antagonist, JNJ 39758979, Is Effective in Reducing Histamine-Induced Pruritus in a Randomized Clinical Study in Healthy Subjects von Kollmeier, Alexa, Francke, Klaus, Chen, Bin, Dunford, Paul J., Greenspan, Andrew J., Xia, Yichuan, Xu, Xie L., Zhou, Bei, Thurmond, Robin L.

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Mass Balance Recovery, Absorption, Metabolism, and Excretion of Elinzanetant in Healthy Human Volunteers and in vitro Biotransformation von Schulz, Simone I, Schultze-Mosgau, Marcus-Hillert, Engelen, Anna, Singh, Nand, Pawsey, Steve, Francke, Klaus, Lock, Ruth, Rottmann, Antje

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Mass Balance and Metabolic Pathways of Eliapixant, a P2X3 Receptor Antagonist, in Healthy Male Volunteers von Reif, Stefanie, Schultze-Mosgau, Marcus-Hillert, Engelen, Anna, Piel, Isabel, Denner, Karsten, Roffel, Ad, Tiessen, Renger, Klein, Stefan, Francke, Klaus, Rottmann, Antje

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Nerve growth factor induces sensitization of nociceptors without evidence for increased intraepidermal nerve fiber density von Hirth, Michael, Rukwied, Roman, Gromann, Alois, Turnquist, Brian, Weinkauf, Benjamin, Francke, Klaus, Albrecht, Philip, Rice, Frank, Hägglöf, Björn, Ringkamp, Matthias, Engelhardt, Maren, Schultz, Christian, Schmelz, Martin, Obreja, Otilia

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Who is a ‘healthy subject’?—consensus results on pivotal eligibility criteria for clinical trials von Breithaupt-Groegler, Kerstin, Coch, Christoph, Coenen, Martin, Donath, Frank, Erb-Zohar, Katharina, Francke, Klaus, Goehler, Karin, Iovino, Mario, Kammerer, Klaus Peter, Mikus, Gerd, Rengelshausen, Jens, Sourgens, Hildegard, Schinzel, Reinhard, Sudhop, Thomas, Wensing, Georg

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Mechanisms of β‐adrenergic Receptor–mediated Venodilation in Humans von Schindler, Christoph, Dobrev, Dobromir, Grossmann, Matthias, Francke, Klaus, Pittrow, David, Kirch, Wilhelm

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Plasma-Enhanced HC-SCR of NO sub(x) in the Presence of Excess Oxygen von Miessner, Hans, Francke, Klaus-Peter, Rudolph, Rolf

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The P2X3 receptor antagonist filapixant in patients with refractory chronic cough: a randomized controlled trial von Friedrich, Christian, Francke, Klaus, Birring, Surinder S, van den Berg, Jan Willem K, Marsden, Paul A, McGarvey, Lorcan, Turner, Alice M, Wielders, Pascal, Gashaw, Isabella, Klein, Stefan, Morice, Alyn H

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Rebalancing transatlantic relations von Francke, Klaus

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