Structure–function analysis of the SHOC2–MRAS–PP1C holophosphatase complex von Kwon, Jason J., Hajian, Behnoush, Bian, Yuemin, Young, Lucy C., Amor, Alvaro J., Fuller, James R., Fraley, Cara V., Sykes, Abbey M., So, Jonathan, Pan, Joshua, Baker, Laura, Lee, Sun Joo, Wheeler, Douglas B., Mayhew, David L., Persky, Nicole S., Yang, Xiaoping, Root, David E., Barsotti, Anthony M., Stamford, Andrew W., Perry, Charles K., Burgin, Alex, McCormick, Frank, Lemke, Christopher T., Hahn, William C., Aguirre, Andrew J.

Volltext

Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs von Dumont, Jennifer A., Liu, Tongyao, Low, Susan C., Zhang, Xin, Kamphaus, George, Sakorafas, Paul, Fraley, Cara, Drager, Douglas, Reidy, Thomas, McCue, Justin, Franck, Helen W.G., Merricks, Elizabeth P., Nichols, Timothy C., Bitonti, Alan J., Pierce, Glenn F., Jiang, Haiyan

Volltext

Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor von Garvie, Colin W., Fraley, Cara V., Elowe, Nadine H., Culyba, Elizabeth K., Lemke, Christopher T., Hubbard, Brian K., Kaushik, Virendar K., Daniels, Douglas S.

Volltext

Reduction of IgG in Nonhuman Primates by a Peptide Antagonist of the Neonatal Fc Receptor FcRn von Mezo, Adam R., McDonnell, Kevin A., Hehir, Cristina A. Tan, Low, Susan C., Palombella, Vito J., Stattel, James M., Kamphaus, George D., Fraley, Cara, Zhang, Yixia, Dumont, Jennifer A., Bitonti, Alan J.

Volltext

Discovery and structure–activity relationships of small molecules that block the human immunoglobulin G–human neonatal Fc receptor (hIgG–hFcRn) protein–protein interaction von Wang, Zhaolin, Fraley, Cara, Mezo, Adam R.

Volltext

Abstract LB029: Comprehensive structure-function evaluation of the SHOC2 holophosphatase reveals disease mechanisms and therapeutic opportunities von Kwon, Jason, Hajian, Behnoush, Bian, Yuemin, Amor, Alvaro, Fuller, James, Fraley, Cara, Baker, Laura, So, Jonathan, Mayhew, David, Sykes, Abbey, Persky, Nicole, Yang, Xiaoping, Root, David, Perry, Charles, Lemke, Christopher, Hahn, William, Aguirre, Andrew

Volltext

Structure–activity relationships of a peptide inhibitor of the human FcRn:human IgG interaction von Mezo, Adam R., McDonnell, Kevin A., Castro, Alfredo, Fraley, Cara

Volltext

Synthesis and Structure−Activity Relationships of Dimeric Peptide Antagonists of the Human Immunoglobulin G−Human Neonatal Fc Receptor (IgG−FcRn) Interaction von McDonnell, Kevin A, Low, Susan C, Hoehn, Todd, Donnelly, Ryan, Palmieri, Holly, Fraley, Cara, Sakorafas, Paul, Mezo, Adam R

Volltext

Factor VIII-Fc Fusion Protein Shows Extended Half-Life and Hemostatic Activity in Hemophilia A Dogs von Dumont, Jennifer A, Kamphaus, George D, Fraley, Cara, Ashworth, Tamera, Franck, Helen, Merricks, Elizabeth P., Nichols, Timothy C., Bitonti, Alan J

Volltext

Cage-Free Pullets Minimally Affected by Stocking Density Stressors von Abraham, Meagan E, Robison, Cara I, Serpa, Priscila B S, Strandberg, Natalia J, Erasmus, Marisa A, Fraley, Gregory S, Erf, Gisela F, Karcher, Darrin M

Volltext

Acetyl analogs of combretastatin A-4: Synthesis and biological studies von Babu, Balaji, Lee, Megan, Lee, Lauren, Strobel, Raymond, Brockway, Olivia, Nickols, Alexis, Sjoholm, Robert, Tzou, Samuel, Chavda, Sameer, Desta, Dereje, Fraley, Gregory, Siegfried, Adam, Pennington, William, Hartley, Rachel M., Westbrook, Cara, Mooberry, Susan L., Kiakos, Konstantinos, Hartley, John A., Lee, Moses

Volltext

Design and synthesis of novel enhanced water soluble hydroxyethyl analogs of combretastatin A-4 von Lee, Megan, Brockway, Olivia, Dandavati, Armaan, Tzou, Samuel, Sjoholm, Robert, Nickols, Alexis, Babu, Balaji, Chavda, Sameer, Satam, Vijay, Hartley, Rachel M., Westbrook, Cara, Mooberry, Susan L., Fraley, Gregory, Lee, Moses

Volltext