Comprehensive Assessment of HIV Target Cells in the Distal Human Gut Suggests Increasing HIV Susceptibility Toward the Anus von McElrath, M J, Smythe, K, Randolph-Habecker, J, Melton, K R, Goodpaster, T A, Hughes, S M, Mack, M, Sato, A, Diaz, G, Steinbach, G, Novak, R M, Curlin, M, Lord, J D, Maenza, J, Duerr, A, Frahm, N, Hladik, Florian

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Robust Bayesian Random Effects Model for Nonlinear Calibration Problems von Fong, Y., Wakefield, J., De Rosa, S., Frahm, N.

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A study of vaccine-induced immune pressure on breakthrough infections in the Phambili phase 2b HIV-1 vaccine efficacy trial von Hertz, T, Logan, M.G, Rolland, M, Magaret, C.A, Rademeyer, C, Fiore-Gartland, A, Edlefsen, P.T, DeCamp, A, Ahmed, H, Ngandu, N, Larsen, B.B, Frahm, N, Marais, J, Thebus, R, Geraghty, D, Hural, J, Corey, L, Kublin, J, Gray, G, McElrath, M.J, Mullins, J.I, Gilbert, P.B, Williamson, C

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Preferential targeting of co-evolving Gag residues in long-term non progressors von Sunshine, J, Shekhar, K, Heckerman, D, Chakraborty, AK, Frahm, N

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Immunogenicity of a universal HIV-1 vaccine vectored by DNA, MVA and CHADV-63 in a Phase I/IIA clinical trial von Borthwick, NJ, Ahmed, T, Rose, A, Ebrahimsa, U, Black, A, Hayton, E, Yang, H, Hancock, G, Campion, S, Frahm, N, Colloca, S, Nicosia, A, McMichael, A, Dorrell, L, Hanke, T

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DNA and recombinant adenovirus serotype 35 and 5 preventive HIV-1 vaccines with Env A inserts elicit cross-clade binding and V1V2 antibodies von Fuchs, JD, Morgan, C, Bart, P, Kochar, N, Frahm, N, Swann, E, Gilbert, P, DeRosa, S, Graham, B, Nabel, G, Liao, H, Haynes, B, Tomaras, G

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First-in-human phase I clinical trial of a recombinant vesicular stomatitis virus (rVSV)-based preventive HIV-1 vaccine von Fuchs, JD, Frank, I, Kochar, N, Elizaga, M, Allen, M, Carter, D, Frahm, N, Kalams, SA, Mulligan, M, Sheets, R, Pensiero, M, Clarke, D, Eldridge, J

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rAd5 prime/NYVAC-B boost regimen is superior to NYVAC-B prime/rAd5 boost regimen for both response rates and magnitude of CD4 and CD8 T-cell responses von Bart, P, Huang, Y, Frahm, N, Karuna, S, Allen, M, Kochar, NK, Chappuis, S, Gaillard, J, Graham, B, Pantaleo, G

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P08-06 LB. A genome-wide association study of host genetic determinants of T cell responses to the MRKAd5 HIV-1 gag/pol/nef vaccine in the STEP trial von Fellay, J, Shianna, KV, Cirulli, ET, McElrath, J, Casimiro, DR, Geraghty, DE, Frahm, N, Goldstein, DB

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P19-48. Induction of Ad5 neutralizing antibodies in placebo recipients during the Step Trial is not associated with risk of HIV infection von Spies, G, Simandl, J, Casimiro, D, DeFawe, O, Noonan, L, Frahm, N, McElrath, MJ

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OA06-06 LB. Evidence of vaccine-induced changes in breakthrough HIV-1 strains from the Step trial von Rolland, M, Tovanabutra, S, Gilbert, PB, Sanders-Buell, E, Heath, L, deCamp, AC, Magaret, CC, Bose, M, Bradfield, A, O'Sullivan, A, Crossler, J, Deng, W, Zhao, H, Wong, K, Raugi, DN, Hural, J, Dubey, S, Frahm, N, Michael, NL, Shiver, J, Corey, L, Li, F, Self, SG, Kim, J, Buchbinder, S, Casimiro, DR, Robertson, MN, McElrath, MJ, McCutchan, FE, Mullins, JI

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Relative Dominance of Gag p24-Specific Cytotoxic T Lymphocytes Is Associated with Human Immunodeficiency Virus Control von ZUNIGA, Rosario, LUCCHETTI, Aldo, HILDEBRAND, William, ALTFELD, Marcus, ALLEN, Todd M, WALKER, Bruce D, KORBER, Bette T, LEITNER, Thomas, SANCHEZ, Jorge, BRANDER, Christian, GALVAN, Patricia, SANCHEZ, Shyla, SANCHEZ, Carmen, HERNANDEZ, Ana, SANCHEZ, Hugo, FRAHM, Nicole, LINDE, Caitlyn H, HEWITT, Hannah S

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P12-09. Immune responses in controlled and uncontrolled HIV infection to a designed HIV immunogen sequence focused on conserved regions of the viral genome von Mothe, B, Llano, A, Ibarrondo, J, Miranda, C, Rolland, M, Frahm, N, Khatri, A, Heckerman, D, Mullins, J, Brander, C

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Adenovirus 5 serotype vector-specific immunity and HIV-1 infection: a tale of T cells and antibodies von D'Souza, M Patricia, Frahm, Nicole

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Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes von Brander, Christian, Frahm, Nicole, Kiepiela, Photini, Adams, Sharon, Linde, Caitlyn H, Hewitt, Hannah S, Sango, Kaori, Feeney, Margaret E, Addo, Marylyn M, Lichterfeld, Mathias, Lahaie, Matthew P, Pae, Eunice, Wurcel, Alysse G, Roach, Timothy, St John, M Anne, Altfeld, Marcus, Marincola, Francesco M, Moore, Corey, Mallal, Simon, Carrington, Mary, Heckerman, David, Allen, Todd M, Mullins, James I, Korber, Bette T, Goulder, Philip J R, Walker, Bruce D

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Comprehensive Analysis of Human Immunodeficiency Virus Type 1-Specific CD4 Responses Reveals Marked Immunodominance of gag and nef and the Presence of Broadly Recognized Peptides von KAUFMANN, Daniel E, BAILEY, Paul M, FRAHM, Nicole, BRANDER, Christian, SETTE, Alessandro, WALKER, Bruce D, ROSENBERG, Eric S, SIDNEY, John, WAGNER, Bradford, NORRIS, Philip J, JOHNSTON, Mary N, COSIMI, Lisa A, ADDO, Marylyn M, LICHTERFELD, Mathias, ALTFELD, Marcus

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De Novo Generation of Escape Variant-Specific CD8+ T-Cell Responses following Cytotoxic T-Lymphocyte Escape in Chronic Human Immunodeficiency Virus Type 1 Infection von ALLEN, Todd M, YU, Xu G, ALTER, Galit, BROWN, Nancy V, JOHNSTON, Mary N, ROSENBERG, Eric S, MALLAL, Simon A, BRANDER, Christian, WALKER, Bruce D, ALTFELD, Marcus, KALIFE, Elizabeth T, REYOR, Laura L, LICHTERFELD, Mathias, JOHN, Mina, CHENG, Michael, ALLGAIER, Rachel L, MUI, Stanley, FRAHM, Nicole

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Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection von BRUMME, Zabrina L, TAO, Iris, HECKERMAN, David, HARRIGAN, P. Richard, SZETO, Sharon, BRUMME, Chanson J, CARLSON, Jonathan M, CHAN, Dennison, KADIE, Carl, FRAHM, Nicole, BRANDER, Christian, WALKER, Bruce

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The Antiviral Efficacy of CD8+ T Cells in Early HIV-1 Infection Is Dependent on Targeting of Low Entropy Regions of the Viral Proteome von Hancock, G, Yang, H, Frahm, N, Dorrell, L, McMichael, A A

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Effective Antiviral CD8+ T Cells Responses Are Rare in HIVPositive Step & Phambili Study Participants but Are Targeted to Low Entropy Viral Epitopes von Hancock, G, Yang, H, McMichael, A J, Frahm, N, McElrath, J M, Dorrell, L

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