Next generation automated traceless cell chromatography platform for GMP-compliant cell isolation and activation von Radisch, Sabine, Poltorak, Mateusz P., Wagner, Michaela, Cletiu, Vlad, Radisch, Christian, Treise, Irina, Pann, Steffi, Weigt, Alexis, Artner, Sophie, Dreher, Stefan, Fechner, Fabian, Borjan, Bojana, Fraessle, Simon P., Effenberger, Manuel, Benke, Eileen, Navratil, Gottfried, Hentschel, Norbert, Busch, Dirk H., Schmidt, Thomas, Stemberger, Christian, Germeroth, Lothar

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Expamers: a new technology to control T cell activation von Poltorak, Mateusz P., Graef, Patricia, Tschulik, Claudia, Wagner, Michaela, Cletiu, Vlad, Dreher, Stefan, Borjan, Bojana, Fraessle, Simon P., Effenberger, Manuel, Turk, Martin, Busch, Dirk H., Plitzko, Juergen, Kugler, David G., Ragan, Seamus, Schmidt, Thomas, Stemberger, Christian, Germeroth, Lothar

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Activation-inducible CAR expression enables precise control over engineered CAR T cell function von Fraessle, Simon P., Tschulik, Claudia, Effenberger, Manuel, Cletiu, Vlad, Gerget, Maria, Schober, Kilian, Busch, Dirk H., Germeroth, Lothar, Stemberger, Christian, Poltorak, Mateusz P.

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A novel polymer-conjugated human IL-15 improves efficacy of CD19-targeted CAR T-cell immunotherapy von Hirayama, Alexandre V., Chou, Cassie K., Miyazaki, Takahiro, Steinmetz, Rachel N., Di, Henna A., Fraessle, Simon P., Gauthier, Jordan, Fiorenza, Salvatore, Hawkins, Reed M., Overwijk, Willem W., Riddell, Stanley R., Marcondes, Mario Q., Turtle, Cameron J.

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Targeted antibody-mediated depletion of murine CD19 CAR T cells permanently reverses B cell aplasia von Paszkiewicz, Paulina J, Fräßle, Simon P, Srivastava, Shivani, Sommermeyer, Daniel, Hudecek, Michael, Drexler, Ingo, Sadelain, Michel, Liu, Lingfeng, Jensen, Michael C, Riddell, Stanley R, Busch, Dirk H

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Role of memory T cell subsets for adoptive immunotherapy von Busch, Dirk H, Fräßle, Simon P, Sommermeyer, Daniel, Buchholz, Veit R, Riddell, Stanley R

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Long-term in vivo microscopy of CAR T cell dynamics during eradication of CNS lymphoma in mice von Mulazzani, Matthias, Fräßle, Simon P., von Mücke-Heim, Iven, Langer, Sigrid, Zhou, Xiaolan, Ishikawa-Ankerhold, Hellen, Leube, Justin, Zhang, Wenlong, Dötsch, Sarah, Svec, Mortimer, Rudelius, Martina, Dreyling, Martin, von Bergwelt-Baildon, Michael, Straube, Andreas, Buchholz, Veit R., Busch, Dirk H., von Baumgarten, Louisa

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Formation and immunomodulatory function of meningeal B-cell aggregates in progressive CNS autoimmunity von Mitsdörffer, Meike, Di Liberto, Giovanni, Dötsch, Sarah, Sie, Christopher, Wagner, Ingrid, Pfaller, Monika, Kreutzfeldt, Mario, Fräßle, Simon, Aly, Lilian, Knier, Benjamin, Busch, Dirk H, Merkler, Doron, Korn, Thomas

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Evaluation of a Fully Human, Hepatitis B Virus-Specific Chimeric Antigen Receptor in an Immunocompetent Mouse Model von Festag, Marvin M., Festag, Julia, Fräßle, Simon P., Asen, Theresa, Sacherl, Julia, Schreiber, Sophia, Mück-Häusl, Martin A., Busch, Dirk H., Wisskirchen, Karin, Protzer, Ulrike

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Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1 von Keestra, A. Marijke, Winter, Maria G., Auburger, Josef J., Fräßle, Simon P., Xavier, Mariana N., Winter, Sebastian E., Kim, Anita, Poon, Victor, Ravesloot, Mariëtta M., Waldenmaier, Julian F. T., Tsolis, Renée M., Eigenheer, Richard A., Bäumler, Andreas J.

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Miniaturized CAR knocked onto CD3ε extends TCR function with CAR specificity under control of endogenous TCR signaling cascade von Manske, Katrin, Dreßler, Lisa, Fräßle, Simon P., Effenberger, Manuel, Tschulik, Claudia, Cletiu, Vlad, Benke, Eileen, Wagner, Michaela, Schober, Kilian, Müller, Thomas R., Stemberger, Christian, Germeroth, Lothar, Busch, Dirk H., Poltorak, Mateusz P.

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Combination of NKTR-255, a Polymer Conjugated Human IL-15, with CD19 CAR T Cell Immunotherapy in a Preclinical Lymphoma Model von Chou, Cassie, Fraessle, Simon, Steinmetz, Rachel, Hawkins, Reed M., Phi, Tinh-Doan, Busch, Dirk, Miyazaki, Takahiro, Marcondes, Mario Q., Riddell, Stanley R., Turtle, Cameron J.

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A chimeric antigen receptor-based cellular safeguard mechanism for selective in vivo depletion of engineered T cells von Svec, Mortimer, Dötsch, Sarah, Warmuth, Linda, Trebo, Manuel, Fräßle, Simon, Riddell, Stanley R, Jäger, Ulrich, D'Ippolito, Elvira, Busch, Dirk H

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Efficient immunoaffinity chromatography of lymphocytes directly from whole blood von Mohr, Fabian, Przibilla, Sabine, Leonhardt, Franziska, Stemberger, Christian, Dreher, Stefan, Müller, Thomas R., Fräßle, Simon P., Schmidt, Georg P., Kiene, Marie-Luise, Stadler, Herbert, Busch, Dirk H.

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METHODS FOR STIMULATING AND TRANSDUCING T CELLS von EFFENBERGER, Manuel, POLTORAK, Mateusz Pawel, FRAESSLE, Simon

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VIRAL-BINDING PROTEIN AND RELATED REAGENTS, ARTICLES, AND METHODS OF USE von EFFENBERGER, Manuel, POLTORAK, Mateusz Pawel, FRAESSLE, Simon

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METHODS FOR STIMULATING AND TRANSDUCING T CELLS von EFFENBERGER, Manuel, POLTORAK, Mateusz Pawel, FRAESSLE, Simon

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METHODS FOR STIMULATING AND TRANSDUCING T CELLS von EFFENBERGER, Manuel, POLTORAK, Mateusz Pawel, FRAESSLE, Simon

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METHODS FOR MANUFACTURING ENGINEERED IMMUNE CELLS von BENKE, Eileen, EFFENBERGER, Manuel, CLETIU, Vlad, POLTORAK, Mateusz Pawel, FRAESSLE, Simon

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Formation and immunomodulatory function of meningeal B cell aggregates in progressive CNS autoimmunity von Mitsdoerffer, Meike, Di Liberto, Giovanni, Doetsch, Sarah, Sie, Christopher, Wagner, Ingrid, Pfaller, Monika, Kreutzfeldt, Mario, Fraessle, Simon, Aly, Lilian, Knier, Benjamin, Busch, Dirk H, Merkler, Doron, Korn, Thomas

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