Immune biomarkers to predict SARS-CoV-2 vaccine effectiveness in patients with hematological malignancies von Tamariz-Amador, Luis-Esteban, Battaglia, Anna Martina, Maia, Catarina, Zherniakova, Anastasiia, Guerrero, Camila, Zabaleta, Aintzane, Burgos, Leire, Botta, Cirino, Fortuño, Maria-Antonia, Grande, Carlos, Manubens, Andrea, Arguiñano, Jose-Maria, Gomez, Clara, Perez-Persona, Ernesto, Olazabal, Iñigo, Oiartzabal, Itziar, Panizo, Carlos, Prosper, Felipe, San-Miguel, Jesus F., Rodriguez-Otero, Paula, Martín-Sánchez, Esperanza, Paiva, Bruno

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Immune dysfunction prior to and during vaccination in multiple myeloma: a case study based on COVID-19 von Martín-Sánchez, Esperanza, Tamariz-Amador, Luis-Esteban, Guerrero, Camila, Zherniakova, Anastasiia, Zabaleta, Aintzane, Maia, Catarina, Blanco, Laura, Alignani, Diego, Fortuño, Maria-Antonia, Grande, Carlos, Manubens, Andrea, Arguiñano, Jose-Maria, Gomez, Clara, Perez-Persona, Ernesto, Olazabal, Iñigo, Oiartzabal, Itziar, Panizo, Carlos, Prosper, Felipe, San-Miguel, Jesus F., Rodriguez-Otero, Paula, Paiva, Bruno

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P1552: AN IMMUNE ATLAS OF THE DYSFUNCTIONAL CELLULAR AND ANTIBODY RESPONSE TO COVID‐19 VACCINATION IN HEMATOLOGICAL PATIENTS WITH A MATURE B‐CELL NEOPLASM von Martín‐Sánchez, Esperanza, Guerrero, Camila, Tamariz‐Amador, Luis‐Esteban, Zherniakova, Anastasiia, Zabaleta, Aintzane, Maia, Catarina, Blanco, Laura, Fortuño, Maria‐Antonia, Grande, Carlos, Manubens, Andrea, Arguiñano, Jose‐Maria, Perez, Clara Gomez, Persona, Ernesto Perez, Eizaguirre, Iñigo Olazabal, Oiartzabal, Itziar, Panizo, Carlos, Prosper, Felipe, Miguel, Jesús San, Rodríguez‐Otero, Paula, Paiva, Bruno

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Cardiomyocyte Apoptotic Cell Death in Arterial Hypertension: Mechanisms and Potential Management von Fortuño, Maria Antonia, Ravassa, Susana, Fortuño, Ana, Zalba, Guillermo, Díez, Javier

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Multicentric study of the effect of pre-analytical variables in the quality of plasma samples stored in biobanks using different complementary proteomic methods von Mateos, Jesús, Carneiro, Isabel, Corrales, Fernando, Elortza, Felix, Paradela, Alberto, del Pino, Manuel Sánchez, Iloro, Ibon, Marcilla, Miguel, Mora, Maria Isabel, Valero, Luz, Ciordia, Sergio, Fernández, Verónica, Fortuño, Maria Antonia, García-Sánchez, Isabel, Martínez, Rosario, Muñoz, Maria Angeles, Rodriguez, Clara, Doménech, Nieves

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A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone von López-Andrés, Natalia, Martin-Fernandez, Beatriz, Rossignol, Patrick, Zannad, Faiez, Lahera, Vicente, Fortuno, Maria Antonia, Cachofeiro, Victoria, Díez, Javier

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Aldosterone Induces Cardiotrophin-1 Expression in HL-1 Adult Cardiomyocytes von López-Andrés, Natalia, Iñigo, Carmen, Gallego, Idoia, Díez, Javier, Fortuño, María Antonia

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Cardiotrophin-1 is expressed in adipose tissue and upregulated in the metabolic syndrome von Natal, Cristina, Fortuno, Maria Antonia, Restituto, Patricia, Bazan, Antonio, Colina, Immaculada, Diez, Javier, Varo, Nerea

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Mechanisms of Increased Susceptibility to Angiotensin II–Induced Apoptosis in Ventricular Cardiomyocytes of Spontaneously Hypertensive Rats von Ravassa, Susana, Fortuño, María Antonia, González, Arantxa, López, Begoña, Zalba, Guillermo, Fortuño, Ana, Díez, Javier

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Cardiomyocyte Apoptosis and Cardiac Angiotensin-Converting Enzyme in Spontaneously Hypertensive Rats von Diez, Javier, Panizo, Angel, Hernandez, Marta, Vega, Francisco, Sola, Iosu, Fortuno, Maria Antonia, Pardo, Javier

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Differential hypertrophic effects of cardiotrophin-1 on adult cardiomyocytes from normotensive and spontaneously hypertensive rats von López, Natalia, Díez, Javier, Fortuño, María Antonia

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Minimal Residual Disease Detection By Single Cell DNA Sequencing Technology: A Feasible Approach for Clinical Application and Identification of the Landscape of MRD Clones von Pierola, Ana Alfonso, Ariceta, Beñat, Vilas-Zornoza, Amaia, Aguirre-Ruiz, Paula, Sarvide, Sarai, San-Martin, Patxi, Fortuño, Maria-Antonia, Simoes, Catia, Burgos, Leire, Larrayoz, Maria Jose, Chillon, Carmen, Arce, Olga, Bernal Del Castillo, Teresa, Colorado, Mercedes, Cuevas Palomares, Laida, Marchante, Inmaculada, Mateos, Maria Carmen, Olave, Mayte, Pérez-Simón, Jose A., Calasanz, Maria Jose, Garcia-Sanz, Ramon, Paiva, Bruno, Montesinos, Pau, Prosper, Felipe

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Deep Characterization of Immune Dysfunction in Patients with Multiple Myeloma (MM) and Identification of Cellular Biomarkers for Tailored Vaccination Strategies von Martín-Sánchez, Esperanza, Guerrero, Camila, Tamariz-Amador, Luis-Esteban, Zherniakova, Anastasiia, Zabaleta, Aintzane, Maia, Catarina, Blanco, Laura, Fortuño, Maria-Antonia, Grande, Carlos, Manubens, Andrea, Arguiñano, Jose Maria, Gomez, Clara, Perez-Persona, Ernesto, Olazabal, Iñigo, Oiartzabal, Itziar, Panizo, Carlos, Prosper, Felipe, San Miguel, Jesús, Rodriguez Otero, Paula, Paiva, Bruno, Asovasna, Basque-Navarre Association of Hematology and Hemotherapy

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PSP/DEGESCO: A Progressive Supranuclear Palsy Genome‐Wide Association Study in the Spanish Population von García‐González, Pablo, de Rojas, Itziar, Rabano, Alberto, Bullido, María J., Puerta, Raquel, Olivé, Clàudia, Álvarez‐Martínez, Victoria, Perez‐Tur, Jordi, Mendioroz, Maite, Fortuño, Maria Antonia, Belbin, Olivia, Compta, Yaroslau, Sanchez‐Juan, Pascual, Tárraga, Lluís, Boada, Mercè, Ruiz, Agustin

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Loss of myocardial LIF receptor in experimental heart failure reduces cardiotrophin-1 cytoprotection. A role for neurohumoral agonists? von LOPEZ, Natalia, VARO, Nerea, DIEZ, Javier, FORTUNO, Maria Antonia

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P-400 An immune atlas of the dysfunctional cellular and antibody response to COVID-19 vaccination in patients with multiple myeloma von Martin-Sanchez, Esperanza, Guerrero, Camila, Tamariz-Amador, Luis-Esteban, Zherniakova, Anastasiia, Zabaleta, Aintzane, Maia, Catarina, Blanco, Laura, Fortuño, Maria-Antonia, Grande, Carlos, Manubens, Andrea, Arguiñano, Jose-Maria, Gomez, Clara, Perez-Persona, Ernesto, Olazabal, Iñigo, Oiartzabal, Itziar, Panizo, Carlos, Prosper, Felipe, San-Miguel, Jesús, Rodriguez-Otero, Paula, Paiva, Bruno, (ASOVASNA), Asociación Vasco-Navarra de Hematología y Hemoterapia

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Overexpression of Bax Protein and Enhanced Apoptosis in the Left Ventricle of Spontaneously Hypertensive Rats: Effects of AT1 Blockade With Losartan von Fortuno, Maria Antonia, Ravassa, Susana, Etayo, Juan Carlos, Diez, Javier

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p53-Mediated Upregulation of BAX Gene Transcription Is Not Involved in Bax-alpha Protein Overexpression in the Left Ventricle of Spontaneously Hypertensive Rats von Fortuno, Maria Antonia, Zalba, Guillermo, Ravassa, Susana, D'Elom, Eva, Beaumont, Francisco J, Fortuno, Ana, Diez, Javier

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Apoptosis in hypertensive heart disease von Díez, Javier, Fortuño, Maria Antonia, Ravassa, Susana

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Aldosterone and the cardiovascular system: a dangerous association von Cachofeiro, Victoria, López-Andrés, Natalia, Miana, Maria, Martín-Fernández, Beatriz, de las Heras, Natalia, Martínez, Ernesto, Lahera, Vicente, Fortuño, María Antonia

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