P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study von Abdulqawi, Rayid, PhD, Dockry, Rachel, MSc, Holt, Kimberley, BSc, Layton, Gary, MSc, McCarthy, Bruce G, MD, Ford, Anthony P, PhD, Smith, Jaclyn A, Prof

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Action of MK‐7264 (gefapixant) at human P2X3 and P2X2/3 receptors and in vivo efficacy in models of sensitisation von Richards, David, Gever, Joel R., Ford, Anthony P., Fountain, Samuel J.

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Purinergic receptors in the carotid body as a new drug target for controlling hypertension von Pijacka, Wioletta, Moraes, Davi J A, Ratcliffe, Laura E K, Nightingale, Angus K, Hart, Emma C, da Silva, Melina P, Machado, Benedito H, McBryde, Fiona D, Abdala, Ana P, Ford, Anthony P, Paton, Julian F R

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Transient receptor potential cation channel, subfamily V, member 4 and airway sensory afferent activation: Role of adenosine triphosphate von Bonvini, Sara J., PhD, Birrell, Mark A., PhD, Grace, Megan S., PhD, Maher, Sarah A., PhD, Adcock, John J., PhD, Wortley, Michael A., PhD, Dubuis, Eric, PhD, Ching, Yee-Man, MRes, Ford, Anthony P., PhD, Shala, Fisnik, MD, Miralpeix, Montserrat, PhD, Tarrason, Gema, PhD, Smith, Jaclyn A., PhD, Belvisi, Maria G., PhD

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In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization von Ford, Anthony P.

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P2X3 receptor antagonism attenuates the progression of heart failure von Lataro, Renata M., Moraes, Davi J. A., Gava, Fabio N., Omoto, Ana C. M., Silva, Carlos A. A., Brognara, Fernanda, Alflen, Lais, Brazão, Vânia, Colato, Rafaela Pravato, do Prado, José Clóvis, Ford, Anthony P., Salgado, Helio C., Paton, Julian F. R.

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The therapeutic promise of ATP antagonism at P2X3 receptors in respiratory and urological disorders von Ford, Anthony P, Undem, Bradley J

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Isoproterenol acts as a biased agonist of the alpha-1A-adrenoceptor that selectively activates the MAPK/ERK pathway von Copik, Alicja J, Baldys, Aleksander, Nguyen, Khanh, Sahdeo, Sunil, Ho, Hoangdung, Kosaka, Alan, Dietrich, Paul J, Fitch, Bill, Raymond, John R, Ford, Anthony P D W, Button, Donald, Milla, Marcos E

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Purinoceptors as therapeutic targets for lower urinary tract dysfunction von Ford, Anthony P D W., Gever, Joel R., Nunn, Philip A., Zhong, Yu, Cefalu, Joseph S., Dillon, Michael P., Cockayne, Debra A.

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Pivotal Role of Nucleotide P2X2 Receptor Subunit of the ATP-Gated Ion Channel Mediating Ventilatory Responses to Hypoxia von Rong, Weifang, Gourine, Alexander V, Cockayne, Debra A, Xiang, Zhenghua, Ford, Anthony P. D. W, Spyer, K. Michael, Burnstock, Geoffrey

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Modulation of bladder afferent signals in normal and spinal cord‐injured rats by purinergic P2X3 and P2X2/3 receptors von Munoz, Alvaro, Somogyi, George T., Boone, Timothy B., Ford, Anthony P., Smith, Christopher P.

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Overexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function von Schnegelsberg, Birthe, Sun, Tung-Tien, Cain, Gary, Bhattacharya, Anindya, Nunn, Philip A, Ford, Anthony P D W, Vizzard, Margaret A, Cockayne, Debra A

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P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP von Cockayne, Debra A., Dunn, Philip M., Zhong, Yu, Rong, Weifang, Hamilton, Sara G., Knight, Gillian E., Ruan, Huai‐Zhen, Ma, Bei, Yip, Ping, Nunn, Philip, McMahon, Stephen B., Burnstock, Geoffrey, Ford, Anthony P. D. W.

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The effect of gefapixant, a P2X3 antagonist, on cough reflex sensitivity: a randomised placebo-controlled study von Morice, Alyn H, Kitt, Michael M, Ford, Anthony P, Tershakovec, Andrew M, Wu, Wen-Chi, Brindle, Kayleigh, Thompson, Rachel, Thackray-Nocera, Susannah, Wright, Caroline

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Gefapixant in two randomised dose-escalation studies in chronic cough von Smith, Jaclyn A., Kitt, Michael M., Butera, Peter, Smith, Steven A., Li, Yuping, Xu, Zhi Jin, Holt, Kimberley, Sen, Shilpi, Sher, Mandel R., Ford, Anthony P.

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Expression and function of bradykinin B1 and B2 receptors in normal and inflamed rat urinary bladder urothelium von Chopra, Bikramjit, Barrick, Stacey R., Meyers, Susan, Beckel, Jonathan M., Zeidel, Mark L., Ford, Anthony P. D. W., De Groat, William C., Birder, Lori A.

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Expression and function of rat urothelial P2Y receptors von Chopra, Bikramjit, Gever, Joel, Barrick, Stacey R, Hanna-Mitchell, Ann T, Beckel, Jonathan M, Ford, Anthony P. D. W, Birder, Lori A

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P2X2 subunits contribute to fast synaptic excitation in myenteric neurons of the mouse small intestine von Ren, Jianhua, Bian, Xiaochun, DeVries, Matthew, Schnegelsberg, Birthe, Cockayne, Debra A., Ford, Anthony P. D. W., Galligan, James J.

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Gefapixant, a P2X3 receptor antagonist, for the treatment of refractory or unexplained chronic cough: a randomised, double-blind, controlled, parallel-group, phase 2b trial von Smith, Jaclyn A, Kitt, Michael M, Morice, Alyn H, Birring, Surinder S, McGarvey, Lorcan P, Sher, Mandel R, Li, Yu-Ping, Wu, Wen-Chi, Xu, Zhi Jin, Muccino, David R, Ford, Anthony P, Smith, Jaclyn, McGarvey, Lorcan, Birring, Surinder, Hull, James, Carr, Warner W, Goldsobel, Alan B, Gross, Gary N, Holcomb, John R, Hussain, Iftikhar, Sher, Mandel, Spangenthal, Selwyn, Storms, William, Morice, Alyn, Elkayam, David, Steven, Gary C, Krainson, James, Fakih, Faisal Alfonso, Matz, Jonathan, Brooks, Gregory Daniel, Casale, Thomas, Berman, Gary D, Condemi, John J, Greos, Leon S, Gogate, Shaila U, Sher, Ellen R, Friesen, Jason H, Schenkel, Eric J, Bernstein, David Isaac, Corren, Jonathan, Sundar, Krishna, Gotfried, Mark H, Montanaro, Anthony, Lumry, William R, Amar, Niran J, Kaplan, Michael S, Prenner, Bruce M, Murphy, Thomas R, Good, James S, Parker, Sean, Harrison, Tim, Pavord, Ian, Brightling, Christopher, Djukanovic, Ratko, McQuaid, Douglas, Denenberg, Michael, Ettinger, Neil A, Iyer, Vivek

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Postsynaptic P2X3‐containing receptors in gustatory nerve fibres mediate responses to all taste qualities in mice von Vandenbeuch, Aurelie, Larson, Eric D., Anderson, Catherine B., Smith, Steven A., Ford, Anthony P., Finger, Thomas E., Kinnamon, Sue C.

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