Mapping of SARS-CoV-2 IgM and IgG in gingival crevicular fluid: Antibody dynamics and linkage to severity of COVID-19 in hospital inpatients von Ijaz, Samreen, Dicks, Steve, Jegatheesan, Keerthana, Parker, Eleanor, Katsanovskaja, Ksenia, Vink, Elen, McClure, Myra O., Shute, J., Hope, Joshua, Cook, Nicola, Cherepanov, Peter, Turtle, Lance, Paxton, William A., Pollakis, Georgios, Ho, Antonia, Openshaw, Peter J.M., Baillie, J. Kenneth, Semple, Malcolm G., Tedder, Richard S.

Volltext

Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study von Knight, Stephen R, Holden, Karl A, Merson, Laura, Russell, Clark D, Solomon, Tom, Carson, Gail, Olliaro, Piero, Semple, Malcolm G, Alex, Beatrice, Bach, Benjamin, Dunning, Jake, da Silva Filipe, Ana, Horby, Peter W, Law, Andrew, Price, Nicholas, Rambaut, Andrew, Robertson, David L, Scott, Janet T, de Silva, Thushan, Sigfrid, Louise, Tedder, Richard S, Thwaites, Ryan S, Turtle, Lance CW, Andrikopoulos, Petros, Liggi, Sonia, Sands, Caroline, Fairfield, Cameron J, Shaw, Catherine A, Dalton, Jo, Girvan, Michelle, Hendry, Ross, Greenhalf, William, McDonald, Sarah E, Booth, Laura, Catterall, Benjamin WA, Clarke, Emily A, Dincarslan, Oslem, Dyer, Philip, Gunning, Philip, Hartley, Catherine, Jensen, Rebecca L, Jones, Christopher B, Khandaker, Shadia, Lefteri, Daniella, Livoti, Lucia A, Middleton, Joanna, Reynolds, Will, Ridley, P. Matthew, Shaw, Victoria E, Tanianis-Hughes, Jolanta, Trochu, Erwan, Flaherty, Lisa, Massey, Hannah, Aldera, Erin L., Alegria, Ana, Barnass, Stella, Barrett, Nicholas, Basude, Sneha, Baxter, David, Beadsworth, Michael, Best, Nicola, Burden, Tom, Chukkambotla, Srikanth, Cutino-Moguel, Maria-Teresa, Douthwaite, Sam, Fullerton, Duncan, Garg, Atul, Hawcutt, Daniel B, Jennings, Paul, Kaliappan, Agilan, Kasipandian, Vidya, Koduri, Gouri, Laird, Steven, Leiner, Tamas, Little, Jeff, McEwen, Ruth, Morris, Craig, Moses, Samuel, Norris, Lillian, Panchatsharam, Selva, Pattison, Natalie, Peters, Mark, Price, David, Prout, Rachel, Richardson, Neil, Rousseau, Guy, Ryan, Brendan, Sharma, Anil, Stambach, Tom, Stewart, Richard, Thompson, Robert, Tridente, Ascanio, Vuylsteke, Alan, Waddy, Sam, Wake, Rachel, Wilson, Lawrence, Wiselka, Martin, Wootton, Daniel G, Workman, Andrew, Young, Peter

Volltext

Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID‐19 von Siggins, Matthew K., Davies, Kate, Fellows, Rosie, Thwaites, Ryan S., Baillie, J. Kenneth, Semple, Malcolm G., Openshaw, Peter J. M., Zelek, Wioleta M., Harris, Claire L., Morgan, B. Paul

Volltext

IL-33 is associated with alveolar dysfunction in patients with viral lower respiratory tract disease von Scott, Ian C, Zuydam, Natalie van, Cann, Jennifer A, Negri, Victor Augusti, Tsafou, Kalliopi, Killick, Helen, Liu, Zhi, McCrae, Christopher, Rees, D Gareth, England, Elizabeth, Guscott, Molly A, Houslay, Kirsty, McCormick, Dominique, Freeman, Anna, Schofield, Darren, Freeman, Adrian, Cohen, E Suzanne, Thwaites, Ryan, Brohawn, Zach, Platt, Adam, Openshaw, Peter J M, Semple, Malcom G, Baillie, J Kenneth, Wilkinson, Tom

Volltext

Fewer COVID‐19 Neurological Complications with Dexamethasone and Remdesivir von Grundmann, Alexander, Wu, Chieh‐Hsi, Hardwick, Marc, Baillie, J. Kenneth, Openshaw, Peter J M, Semple, Malcolm G., Böhning, Dankmar, Pett, Sarah, Michael, Benedict D., Thomas, Rhys H., Galea, Ian

Volltext

Genetic mechanisms of critical illness in COVID-19 von Pairo-Castineira, Erola, Clohisey, Sara, Klaric, Lucija, Bretherick, Andrew D., Rawlik, Konrad, Pasko, Dorota, Walker, Susan, Parkinson, Nick, Fourman, Max Head, Russell, Clark D., Furniss, James, Richmond, Anne, Gountouna, Elvina, Wrobel, Nicola, Harrison, David, Wang, Bo, Wu, Yang, Meynert, Alison, Griffiths, Fiona, Oosthuyzen, Wilna, Kousathanas, Athanasios, Moutsianas, Loukas, Yang, Zhijian, Zhai, Ranran, Zheng, Chenqing, Grimes, Graeme, Beale, Rupert, Millar, Jonathan, Shih, Barbara, Keating, Sean, Zechner, Marie, Haley, Chris, Porteous, David J., Hayward, Caroline, Yang, Jian, Knight, Julian, Summers, Charlotte, Shankar-Hari, Manu, Klenerman, Paul, Turtle, Lance, Ho, Antonia, Moore, Shona C., Hinds, Charles, Horby, Peter, Nichol, Alistair, Maslove, David, Ling, Lowell, McAuley, Danny, Montgomery, Hugh, Walsh, Timothy, Pereira, Alexandre C., Renieri, Alessandra, Shen, Xia, Ponting, Chris P., Fawkes, Angie, Tenesa, Albert, Caulfield, Mark, Scott, Richard, Rowan, Kathy, Murphy, Lee, Openshaw, Peter J. M., Semple, Malcolm G., Law, Andrew, Vitart, Veronique, Wilson, James F., Baillie, J. Kenneth

Volltext

Comparison of UK paediatric SARS-CoV-2 admissions across the first and second pandemic waves von Swann, Olivia V., Pollock, Louisa, Holden, Karl A., Munro, Alasdair P. S., Bennett, Aisleen, Williams, Thomas C., Turtle, Lance, Fairfield, Cameron J., Drake, Thomas M., Faust, Saul N., Sinha, Ian P., Roland, Damian, Whittaker, Elizabeth, Ladhani, Shamez N., Nguyen-Van-Tam, Jonathan S., Girvan, Michelle, Donohue, Chloe, Donegan, Cara, Spencer, Rebecca G., Hardwick, Hayley E., Openshaw, Peter J. M., Baillie, J. Kenneth, Harrison, Ewen M., Docherty, Annemarie B., Semple, Malcolm G.

Volltext

Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study von Docherty, Annemarie B, Harrison, Ewen M, Green, Christopher A, Hardwick, Hayley E, Pius, Riinu, Norman, Lisa, Holden, Karl A, Read, Jonathan M, Dondelinger, Frank, Carson, Gail, Merson, Laura, Lee, James, Plotkin, Daniel, Sigfrid, Louise, Halpin, Sophie, Jackson, Clare, Gamble, Carrol, Horby, Peter W, Nguyen-Van-Tam, Jonathan S, Ho, Antonia, Russell, Clark D, Dunning, Jake, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G

Volltext

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score von Knight, Stephen R, Ho, Antonia, Pius, Riinu, Buchan, Iain, Carson, Gail, Drake, Thomas M, Dunning, Jake, Fairfield, Cameron J, Gamble, Carrol, Green, Christopher A, Gupta, Rishi, Halpin, Sophie, Hardwick, Hayley E, Holden, Karl A, Horby, Peter W, Jackson, Clare, Mclean, Kenneth A, Merson, Laura, Nguyen-Van-Tam, Jonathan S, Norman, Lisa, Noursadeghi, Mahdad, Olliaro, Piero L, Pritchard, Mark G, Russell, Clark D, Shaw, Catherine A, Sheikh, Aziz, Solomon, Tom, Sudlow, Cathie, Swann, Olivia V, Turtle, Lance CW, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G, Docherty, Annemarie B, Harrison, Ewen M

Volltext

Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study von Halpin, Sophie, Donohue, Chloe, Ladhani, Shamez, Horby, Peter W, Docherty, Annemarie B, Semple, Malcolm G, Openshaw, Peter J M, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Horby, Peter W, Klenerman, Paul, Law, Andrew, Moore, Shona C, Palmarini, Massimo, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Thomson, Emma C, Oosthuyzen, Wilna, Norman, Lisa, Pius, Riinu, Mclean, Kenneth A, Saviciute, Egle, Leeming, Gary, Hendry, Ross, Greenhalf, William, Ahmed, Katie A, Asiimwe, Innocent G, Brennan, Benjamin, Catterall, Benjamin WA, Clark, Jordan J, Cole, Sarah, Cox, Helen, Elliott, Angela, Foster, Terry, Greenhalf, Willliam, Jones, Trevor R, Murphy, Ellen G, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis, Jolanta, Trochu, Erwan, van Tonder, Libby, Wilcock, Eve, Agranoff, Daniel, Angus, Brian, Atkinson, Dougal, Barlow, Gavin, Barrett, Nicholas, Bassford, Christopher, Beadsworth, Michael, Best, Nicola, Burden, Tom, Chukkambotla, Srikanth, Cupitt, Jason, Dark, Paul, Dushianthan, Ahilanadan, Dyer, Tristan, Evans, Cariad, Fegan, Christopher, Finn, Adam, Fullerton, Duncan, Goldsmith, Arthur, Hardy, Elaine, Havalda, Peter, Holme, Anita, Kendall, Jason, Kerrison, Caroline, Larkin, Susan, Leiner, Tamas, Lillie, Patrick, MacNaughton, Emily, McCullough, Katherine, Moore, Elinoor, Morgan, Patrick, Morris, Craig, Nelson, Mark, Panchatsharam, Selva, Pintus, Stefania, Prout, Rachel, Rousseau, Guy, Ryan, Brendan, Saluja, Taranprit, Shanmuga, Prad, Sharma, Anil, Sizer, Jeremy, Smith, Richard, Snelson, Catherine, Spittle, Nick, Stambach, Tom, Tridente, Ascanio, Ustianowski, Andrew, Waddy, Sam, Whittaker, Paul, Williams, Martin, Wiselka, Martin, Young, Peter

Volltext

SARS-CoV-2 co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses von Swets, Maaike C, Russell, Clark D, Harrison, Ewen M, Docherty, Annemarie B, Lone, Nazir, Girvan, Michelle, Hardwick, Hayley E, Visser, Leonardus G, Openshaw, Peter J M, Groeneveld, Geert H, Semple, Malcolm G, Baillie, J Kenneth

Volltext

Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity von Thomson, Emma C., Rosen, Laura E., Shepherd, James G., Spreafico, Roberto, da Silva Filipe, Ana, Wojcechowskyj, Jason A., Davis, Chris, Piccoli, Luca, Pascall, David J., Dillen, Josh, Lytras, Spyros, Czudnochowski, Nadine, Shah, Rajiv, Meury, Marcel, Jesudason, Natasha, De Marco, Anna, Li, Kathy, Bassi, Jessica, O’Toole, Aine, Pinto, Dora, Colquhoun, Rachel M., Culap, Katja, Jackson, Ben, Zatta, Fabrizia, Rambaut, Andrew, Jaconi, Stefano, Sreenu, Vattipally B., Nix, Jay, Zhang, Ivy, Jarrett, Ruth F., Glass, William G., Beltramello, Martina, Nomikou, Kyriaki, Pizzuto, Matteo, Tong, Lily, Cameroni, Elisabetta, Croll, Tristan I., Johnson, Natasha, Di Iulio, Julia, Wickenhagen, Arthur, Ceschi, Alessandro, Harbison, Aoife M., Mair, Daniel, Ferrari, Paolo, Smollett, Katherine, Sallusto, Federica, Carmichael, Stephen, Garzoni, Christian, Nichols, Jenna, Galli, Massimo, Hughes, Joseph, Riva, Agostino, Ho, Antonia, Schiuma, Marco, Semple, Malcolm G., Openshaw, Peter J.M., Fadda, Elisa, Baillie, J. Kenneth, Chodera, John D., Rihn, Suzannah J., Lycett, Samantha J., Virgin, Herbert W., Telenti, Amalio, Corti, Davide, Robertson, David L., Snell, Gyorgy

Volltext

A prenylated dsRNA sensor protects against severe COVID-19 von Wickenhagen, Arthur, Sugrue, Elena, Lytras, Spyros, Kuchi, Srikeerthana, Noerenberg, Marko, Turnbull, Matthew L, Loney, Colin, Herder, Vanessa, Allan, Jay, Jarmson, Innes, Cameron-Ruiz, Natalia, Varjak, Margus, Pinto, Rute M, Lee, Jeffrey Y, Iselin, Louisa, Palmalux, Natasha, Stewart, Douglas G, Swingler, Simon, Greenwood, Edward J D, Crozier, Thomas W M, Gu, Quan, Davies, Emma L, Clohisey, Sara, Wang, Bo, Trindade Maranhão Costa, Fabio, Freire Santana, Monique, de Lima Ferreira, Luiz Carlos, Murphy, Lee, Fawkes, Angie, Meynert, Alison, Grimes, Graeme, Da Silva Filho, Joao Luiz, Marti, Matthias, Hughes, Joseph, Stanton, Richard J, Wang, Eddie C Y, Ho, Antonia, Davis, Ilan, Jarrett, Ruth F, Castello, Alfredo, Robertson, David L, Semple, Malcolm G, Openshaw, Peter J M, Palmarini, Massimo, Lehner, Paul J, Baillie, J Kenneth, Rihn, Suzannah J, Wilson, Sam J

Volltext

Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease. An International Multicenter Study von Drake, Thomas M, Docherty, Annemarie B, Harrison, Ewen M, Quint, Jennifer K, Adamali, Huzaifa, Agnew, Sarah, Babu, Suresh, Barber, Christopher M, Barratt, Shaney, Bendstrup, Elisabeth, Bianchi, Stephen, Villegas, Diego Castillo, Chaudhuri, Nazia, Chua, Felix, Coker, Robina, Chang, William, Crawshaw, Anjali, Crowley, Louise E, Dosanjh, Davinder, Fiddler, Christine A, Forrest, Ian A, George, Peter M, Gibbons, Michael A, Groom, Katherine, Haney, Sarah, Hart, Simon P, Heiden, Emily, Henry, Michael, Ho, Ling-Pei, Hoyles, Rachel K, Hutchinson, John, Hurley, Killian, Jones, Mark, Jones, Steve, Kokosi, Maria, Kreuter, Michael, MacKay, Laura S, Mahendran, Siva, Margaritopoulos, George, Molina-Molina, Maria, Molyneaux, Philip L, O'Brien, Aiden, O'Reilly, Katherine, Packham, Alice, Parfrey, Helen, Poletti, Venerino, Porter, Joanna C, Renzoni, Elisabetta, Rivera-Ortega, Pilar, Russell, Anne-Marie, Saini, Gauri, Spencer, Lisa G, Stella, Giulia M, Stone, Helen, Sturney, Sharon, Thickett, David, Thillai, Muhunthan, Wallis, Tim, Ward, Katie, Wells, Athol U, West, Alex, Wickremasinghe, Melissa, Woodhead, Felix, Hearson, Glenn, Howard, Lucy, Baillie, J Kenneth, Openshaw, Peter J M, Semple, Malcolm G, Stewart, Iain, Jenkins, R Gisli

Volltext

Hospital-acquired SARS-CoV-2 infection in the UK's first COVID-19 pandemic wave von Read, Jonathan M, Green, Chris A, Harrison, Ewen M, Docherty, Annemarie B, Funk, Sebastian, Harrison, Janet, Girvan, Michelle, Hardwick, Hayley E, Turtle, Lance, Dunning, Jake, Nguyen-Van-Tam, Jonathan S, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G

Volltext

Estimating distribution of length of stay in a multi-state model conditional on the pathway, with an application to patients hospitalised with Covid-19 von Keogh, Ruth H., Diaz-Ordaz, Karla, Jewell, Nicholas P., Semple, Malcolm G., de Wreede, Liesbeth C., Putter, Hein

Volltext

Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, pr... von Fairfield, Cameron J, Drake, Thomas M, Sigfrid, Louise, Docherty, Annemarie B, Girvan, Michelle, Dunning, Jake, Openshaw, Peter J M, Openshaw, Peter JM, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Law, Andrew, Merson, Laura, Moore, Shona C, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Tedder, Richard S, Palmieri, Carlo, Knight, Stephen R, Shaw, Catherine A, Marsh, Laura, Shaw, Victoria, McDonald, Sarah E, Keating, Seán, Armstrong, Jane A, Ashworth, Milton, Booth, Laura, Brennan, Benjamin, Bullock, Katie, Cooper, Louise, Davis, Christopher, Dincarslan, Oslem, Dunn, Chris, Evans, Anthony, Garcia-Dorival, Isabel, Jones, Christopher B, Khandaker, Shadia, Lant, Suzannah, Lavelle-Langham, Lara, Lefteri, Daniella, Lett, Lauren, Livoti, Lucia A, Mancini, Maria, McLauchlan, John, Murphy, Ellen G, Penrice-Randal, Rebekah, Pilgrim, Jack, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis-Hughes, Jolanta, van Tonder, Libby, Wilcock, Eve, Flaherty, Lisa, MacLean, Alan, Agranoff, Daniel, Aldera, Erin L., Alegria, Ana, Bari, Shahedal, Barlow, Gavin, Barnass, Stella, Basude, Sneha, Chadwick, David, Chee, Nigel, Chukkambotla, Srikanth, Cutino-Moguel, Maria-Teresa, Dark, Paul, Donnison, Phil, Douthwaite, Sam, Dushianthan, Ahilanadan, Eziefula, Chi, Fegan, Chrisopher, Garg, Atul, Hawcutt, Daniel B, Hobrok, Maria, Jennings, Paul, Koduri, Gouri, Laha, Shondipon, Laird, Steven, MacNaughton, Emily, Mankregod, Ravish, Masson, Huw, McCullough, Katherine, Mirfenderesky, Mariyam, Mohandas, Kavya, Morris, Craig, Nagel, Megan, Papakonstantino, Danai, Pintus, Stefania, Singh Pooni, Jagtur, Prout, Rachel, Roberts, Devender, Rose, Alistair, Shawcross, Anna, Tatham, Kate, Vuylsteke, Alan, Whittaker, Paul, Wiselka, Martin

Volltext

Plasma steroid concentrations reflect acute disease severity and normalise during recovery in people hospitalised with COVID‐19 von Devine, Kerri, Russell, Clark D., Blanco, Giovanny R., Walker, Brian R., Homer, Natalie Z. M., Denham, Scott G., Simpson, Joanna P., Leavy, Olivia C., Elneima, Omer, McAuley, Hamish J. C., Shikotra, Aarti, Singapuri, Amisha, Sereno, Marco, Saunders, Ruth M., Harris, Victoria C., Houchen‐Wolloff, Linzy, Greening, Neil J., Lone, Nazir I., Thorpe, Mathew, Greenhalf, William, Chalmers, James D., Ho, Ling‐Pei, Horsley, Alex, Marks, Michael, Raman, Betty, Moore, Shona C., Dunning, Jake, Semple, Malcolm G., Andrew, Ruth, Wain, Louise V., Evans, Rachael A., Brightling, Christopher E., Kenneth Baillie, John, Reynolds, Rebecca M.

Volltext

Outcome of COVID-19 in hospitalised immunocompromised patients: An analysis of the WHO ISARIC CCP-UK prospective cohort study von Turtle, Lance, Thorpe, Mathew, Drake, Thomas M, Swets, Maaike, Palmieri, Carlo, Russell, Clark D, Ho, Antonia, Aston, Stephen, Wootton, Daniel G, Richter, Alex, de Silva, Thushan I, Hardwick, Hayley E, Leeming, Gary, Law, Andy, Openshaw, Peter J M, Harrison, Ewen M, Baillie, J Kenneth, Semple, Malcolm G, Docherty, Annemarie B

Volltext

Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: a prospective, multicentre cohort study von Sullivan, Michael K, Lees, Jennifer S, Drake, Thomas M, Docherty, Annemarie B, Oates, Georgia, Hardwick, Hayley E, Russell, Clark D, Merson, Laura, Dunning, Jake, Nguyen-Van-Tam, Jonathan S, Openshaw, Peter, Harrison, Ewen M, Baillie, J Kenneth, Semple, Malcolm G, Ho, Antonia, Mark, Patrick B

Volltext