Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE von Parhizkar, Samira, Arzberger, Thomas, Brendel, Matthias, Kleinberger, Gernot, Deussing, Maximilian, Focke, Carola, Nuscher, Brigitte, Xiong, Monica, Ghasemigharagoz, Alireza, Katzmarski, Natalie, Krasemann, Susanne, Lichtenthaler, Stefan F., Müller, Stephan A., Colombo, Alessio, Monasor, Laura Sebastian, Tahirovic, Sabina, Herms, Jochen, Willem, Michael, Pettkus, Nadine, Butovsky, Oleg, Bartenstein, Peter, Edbauer, Dieter, Rominger, Axel, Ertürk, Ali, Grathwohl, Stefan A., Neher, Jonas J., Holtzman, David M., Meyer-Luehmann, Melanie, Haass, Christian

Volltext

The FTD‐like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism von Kleinberger, Gernot, Brendel, Matthias, Mracsko, Eva, Wefers, Benedikt, Groeneweg, Linda, Xiang, Xianyuan, Focke, Carola, Deußing, Maximilian, Suárez‐Calvet, Marc, Mazaheri, Fargol, Parhizkar, Samira, Pettkus, Nadine, Wurst, Wolfgang, Feederle, Regina, Bartenstein, Peter, Mueggler, Thomas, Arzberger, Thomas, Knuesel, Irene, Rominger, Axel, Haass, Christian

Volltext

Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study von Brendel, Matthias, Focke, Carola, Blume, Tanja, Peters, Finn, Deussing, Maximilian, Probst, Federico, Jaworska, Anna, Overhoff, Felix, Albert, Nathalie, Lindner, Simon, von Ungern-Sternberg, Barbara, Bartenstein, Peter, Haass, Christian, Kleinberger, Gernot, Herms, Jochen, Rominger, Axel

Volltext

Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study von Blume, Tanja, Focke, Carola, Peters, Finn, Deussing, Maximilian, Albert, Nathalie L, Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Ozmen, Laurence, Baumann, Karlheinz, Bartenstein, Peter, Rominger, Axel, Herms, Jochen, Brendel, Matthias

Volltext

Expression of Translocator Protein and [18F]-GE180 Ligand Uptake in Multiple Sclerosis Animal Models von Nack, Anne, Brendel, Matthias, Nedelcu, Julia, Daerr, Markus, Nyamoya, Stella, Beyer, Cordian, Focke, Carola, Deussing, Maximilian, Hoornaert, Chloé, Ponsaerts, Peter, Schmitz, Christoph, Bartenstein, Peter, Rominger, Axel, Kipp, Markus

Volltext

Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition von Blume, Tanja, Deussing, Maximilian, Biechele, Gloria, Peters, Finn, Zott, Benedikt, Schmidt, Claudio, Franzmeier, Nicolai, Wind, Karin, Eckenweber, Florian, Sacher, Christian, Shi, Yuan, Ochs, Katharina, Kleinberger, Gernot, Xiang, Xianyuan, Focke, Carola, Lindner, Simon, Gildehaus, Franz-Josef, Beyer, Leonie, von Ungern-Sternberg, Barbara, Bartenstein, Peter, Baumann, Karlheinz, Adelsberger, Helmuth, Rominger, Axel, Cumming, Paul, Willem, Michael, Dorostkar, Mario M, Herms, Jochen, Brendel, Matthias

Volltext

Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology von Brendel, Matthias, Yousefi, Behrooz H., Blume, Tanja, Herz, Michael, Focke, Carola, Deussing, Maximilian, Peters, Finn, Lindner, Simon, von Ungern-Sternberg, Barbara, Drzezga, Alexander, Bartenstein, Peter, Haass, Christian, Okamura, Nobuyuki, Herms, Jochen, Yakushev, Igor, Rominger, Axel

Volltext

Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium von Deussing, Maximilian, Blume, Tanja, Vomacka, Lena, Mahler, Christoph, Focke, Carola, Todica, Andrei, Unterrainer, Marcus, Albert, Nathalie L., Lindner, Simon, von Ungern-Sternberg, Barbara, Baumann, Karlheinz, Zwergal, Andreas, Bartenstein, Peter, Herms, Jochen, Rominger, Axel, Brendel, Matthias

Volltext

Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice von Focke, Carola, Blume, Tanja, Zott, Benedikt, Shi, Yuan, Deussing, Maximilian, Peters, Finn, Schmidt, Claudio, Kleinberger, Gernot, Lindner, Simon, Gildehaus, Franz-Josef, Beyer, Leonie, von Ungern-Sternberg, Barbara, Bartenstein, Peter, Ozmen, Laurence, Baumann, Karlheinz, Dorostkar, Mario M, Haass, Christian, Adelsberger, Helmuth, Herms, Jochen, Rominger, Axel, Brendel, Matthias

Volltext

Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models von Sacher, Christian, Blume, Tanja, Beyer, Leonie, Biechele, Gloria, Sauerbeck, Julia, Eckenweber, Florian, Deussing, Maximilian, Focke, Carola, Parhizkar, Samira, Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Baumann, Karlheinz, Tahirovic, Sabina, Kleinberger, Gernot, Willem, Michael, Haass, Christian, Bartenstein, Peter, Cumming, Paul, Rominger, Axel, Herms, Jochen, Brendel, Matthias

Volltext

Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo [mu]PET-study von Blume, Tanja, Focke, Carola, Peters, Finn, Deussing, Maximilian, Albert, Nathalie L, Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Ozmen, Laurence, Baumann, Karlheinz, Bartenstein, Peter, Rominger, Axel, Herms, Jochen, Brendel, Matthias

Volltext

Author Correction: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE von Parhizkar, Samira, Arzberger, Thomas, Brendel, Matthias, Kleinberger, Gernot, Deussing, Maximilian, Focke, Carola, Nuscher, Brigitte, Xiong, Monica, Ghasemigharagoz, Alireza, Katzmarski, Natalie, Krasemann, Susanne, Lichtenthaler, Stefan F., Müller, Stephan A., Colombo, Alessio, Monasor, Laura Sebastian, Tahirovic, Sabina, Herms, Jochen, Willem, Michael, Pettkus, Nadine, Butovsky, Oleg, Bartenstein, Peter, Edbauer, Dieter, Rominger, Axel, Ertürk, Ali, Grathwohl, Stefan A., Neher, Jonas J., Holtzman, David M., Meyer-Luehmann, Melanie, Haass, Christian

Volltext

Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [18F]GE180 PET quantification von Deussing, Maximilian, Blume, Tanja, Vomacka, Lena, Mahler, Christoph, Focke, Carola, Todica, Andrei, Unterrainer, Marcus, Albert, Nathalie L., Lindner, Simon, von Ungern-Sternberg, Barbara, Baumann, Karlheinz, Zwergal, Andreas, Bartenstein, Peter, Herms, Jochen, Rominger, Axel, Brendel, Matthias

Volltext

Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice von Overhoff, Felix, Brendel, Matthias, Jaworska, Anna, Korzhova, Viktoria, Delker, Andreas, Probst, Federico, Focke, Carola, Gildehaus, Franz-Josef, Carlsen, Janette, Baumann, Karlheinz, Haass, Christian, Bartenstein, Peter, Herms, Jochen, Rominger, Axel

Volltext

Neuroinflammation und ihr prädiktiver Einfluss auf die kognitive Leistung im Alzheimer-Mausmodell von Focke, Carola

Volltext bestellen

Increasing fibrillar amyloidosis is associated with improved cognition and synaptic preservation caused by microglia modulation von Deussing, Maximilian, Blume, Tanja, Zott, Benedikt, Shi, Yuan, Kleinberger, Gernot, Focke, Carola, Lindner, Simon, Gildehaus, Franz-Josef, Beyer, Leonie, von Ungern-Sternberg, Barbara, Bartenstein, Peter, Ozmen, Laurence, Baumann, Karlheinz, Dorostkar, Mario, Haass, Christian, Adelsberger, Helmuth, Rominger, Axel, Herms, Jochen, Brendel, Matthias

Volltext

Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation von Biechele, Gloria, Blume, Tanja, Deussing, Maximilian, Zott, Benedikt, Shi, Yuan, Xiang, Xianyuan, Franzmeier, Nicolai, Kleinberger, Gernot, Peters, Finn, Ochs, Katharina, Focke, Carola, Sacher, Christian, Wind, Karin, Schmidt, Claudio, Lindner, Simon, Gildehaus, Franz-Josef, Eckenweber, Florian, Beyer, Leonie, von Ungern-Sternberg, Barbara, Bartenstein, Peter, Baumann, Karlheinz, Dorostkar, Mario M, Rominger, Axel, Cumming, Paul, Willem, Michael, Adelsberger, Helmuth, Herms, Jochen, Brendel, Matthias

Volltext

Early and longitudinal microglial activation but not fibrillar amyloid accumulation predict cognitive outcome in PS2APP mice von Brendel, Matthias, Focke, Carola, Deussing, Maximilian, Zott, Benedikt, Blume, Tanja, Shi, Yuan, Beyer, Leonie, Kleinberger, Gernot, Lindner, Simon, Gildehaus, Franz-Josef, Bartenstein, Peter, Haass, Christian, Herms, Jochen, Adelsberger, Helmuth, Rominger, Axel

Volltext

Microglial Response to Increasing Amyloidosis Saturates During Aging of an Alzheimer's Disease Mouse Model von Brendel, Matthias, Blume, Tanja, Focke, Carola, Peters, Finn, Deussing, Maximilian, Beyer, Leonie, Albert, Nathalie, Lindner, Simon, Gildehaus, Franz Josef, Ungern-Sternberg, Barbara Von, Bartenstein, Peter, Herms, Jochen, Rominger, Axel

Volltext

Asymmetry of plaque burden in amyloid mouse models von Biechele, Gloria, Sacher, Christian, Blume, Tanja, Beyer, Leonie, Sauerbeck, Julia, Eckenweber, Florian, Deussing, Maximilian, Focke, Carola, Parhizkar, Samira, Lindner, Simon, Gildehaus, Franz Josef, von Ungern‐Sternberg, Barbara, Baumann, Karlheinz, Tahirovic, Sabina, Kleinberger, Gernot, Willem, Michael, Haass, Christian, Bartenstein, Peter, Cumming, Paul, Rominger, Axel, Herms, Jochen, Brendel, Matthias

Volltext