The kinome 'at large' in cancer von Fleuren, Emmy D. G., Zhang, Luxi, Wu, Jianmin, Daly, Roger J.

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ATR Is a Therapeutic Target in Synovial Sarcoma von Jones, Samuel E, Fleuren, Emmy D G, Frankum, Jessica, Konde, Asha, Williamson, Chris T, Krastev, Dragomir B, Pemberton, Helen N, Campbell, James, Gulati, Aditi, Elliott, Richard, Menon, Malini, Selfe, Joanna L, Brough, Rachel, Pettitt, Stephen J, Niedzwiedz, Wojciech, van der Graaf, Winette T A, Shipley, Janet, Ashworth, Alan, Lord, Christopher J

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Targeted Therapy-based Combination Treatment in Rhabdomyosarcoma von van Erp, Anke E M, Versleijen-Jonkers, Yvonne M H, van der Graaf, Winette T A, Fleuren, Emmy D G

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Phosphoproteomic Profiling Reveals ALK and MET as Novel Actionable Targets across Synovial Sarcoma Subtypes von Fleuren, Emmy D G, Vlenterie, Myrella, van der Graaf, Winette T A, Hillebrandt-Roeffen, Melissa H S, Blackburn, James, Ma, Xiuquan, Chan, Howard, Magias, Mandy C, van Erp, Anke, van Houdt, Laurens, Cebeci, Sabri A S, van de Ven, Amy, Flucke, Uta E, Heyer, Erin E, Thomas, David M, Lord, Christopher J, Marini, Kieren D, Vaghjiani, Vijesh, Mercer, Tim R, Cain, Jason E, Wu, Jianmin, Versleijen-Jonkers, Yvonne M H, Daly, Roger J

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Expression and clinical relevance of MET and ALK in Ewing sarcomas von Fleuren, Emmy D.G., Roeffen, Melissa H.S., Leenders, William P., Flucke, Uta E., Vlenterie, Myrella, Schreuder, Hendrik W., Boerman, Otto C., Graaf, Winette T.A., Versleijen‐Jonkers, Yvonne M.H.

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The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma von Fleuren, Emmy D G, Hillebrandt-Roeffen, Melissa H S, Flucke, Uta E, Te Loo, D Maroeska W M, Boerman, Otto C, van der Graaf, Winette T A, Versleijen-Jonkers, Yvonne M H

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Theranostic applications of antibodies in oncology von Fleuren, Emmy D.G., Versleijen-Jonkers, Yvonne M.H., Heskamp, Sandra, van Herpen, Carla M.L., Oyen, Wim J.G., van der Graaf, Winette T.A., Boerman, Otto C.

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Overexpression of the oncogenic signal transducer Gab2 occurs early in breast cancer development von Fleuren, Emmy D.G., O'Toole, Sandra, Millar, Ewan K., McNeil, Catriona, Lopez‐Knowles, Elena, Boulghourjian, Alice, Croucher, David R., Schramek, Daniel, Brummer, Tilman, Penninger, Josef M., Sutherland, Robert L., Daly, Roger J.

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The strength of small: Improved targeting of Insulin-like Growth Factor-1 Receptor (IGF-1R) with F(ab′)2 -R1507 fragments in Ewing sarcomas von Fleuren, Emmy D.G, Versleijen-Jonkers, Yvonne M.H, Heskamp, Sandra, Roeffen, Melissa H.S, Bouwman, Wilbert H, Molkenboer-Kuenen, Janneke D.M, van Laarhoven, Hanneke W.M, Oyen, Wim J.G, Boerman, Otto C, van der Graaf, Winette T.A

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Biological and clinical implications of FGFR aberrations in paediatric and young adult cancers von Brown, Lauren M., Ekert, Paul G., Fleuren, Emmy D. G.

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Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer von Wong, Marie, Mayoh, Chelsea, Lau, Loretta M. S., Khuong-Quang, Dong-Anh, Pinese, Mark, Kumar, Amit, Barahona, Paulette, Wilkie, Emilie E., Sullivan, Patricia, Bowen-James, Rachel, Syed, Mustafa, Martincorena, Iñigo, Abascal, Federico, Sherstyuk, Alexandra, Bolanos, Noemi A., Baber, Jonathan, Priestley, Peter, Dolman, M. Emmy M., Fleuren, Emmy D. G., Gauthier, Marie-Emilie, Mould, Emily V. A., Gayevskiy, Velimir, Gifford, Andrew J., Grebert-Wade, Dylan, Strong, Patrick A., Manouvrier, Elodie, Warby, Meera, Thomas, David M., Kirk, Judy, Tucker, Katherine, O’Brien, Tracey, Alvaro, Frank, McCowage, Geoffry B., Dalla-Pozza, Luciano, Gottardo, Nicholas G., Tapp, Heather, Wood, Paul, Khaw, Seong-Lin, Hansford, Jordan R., Moore, Andrew S., Norris, Murray D., Trahair, Toby N., Lock, Richard B., Tyrrell, Vanessa, Haber, Michelle, Marshall, Glenn M., Ziegler, David S., Ekert, Paul G., Cowley, Mark J.

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Precision medicine and phosphoproteomics for the identification of novel targeted therapeutic avenues in sarcomas von Fordham, Ashleigh M., Ekert, Paul G., Fleuren, Emmy D.G.

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Systemic Treatment for Adults with Synovial Sarcoma von Desar, Ingrid M. E., Fleuren, Emmy D. G., van der Graaf, Winette T. A.

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Recent advances on anti-angiogenic multi-receptor tyrosine kinase inhibitors in osteosarcoma and Ewing sarcoma von Fleuren, Emmy D G, Vlenterie, Myrella, van der Graaf, Winette T A

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Olaparib and temozolomide in desmoplastic small round cell tumors: a promising combination in vitro and in vivo von van Erp, Anke E. M., van Houdt, Laurens, Hillebrandt-Roeffen, Melissa H. S., van Bree, Niek F. H. N., Flucke, Uta E., Mentzel, Thomas, Shipley, Janet, Desar, Ingrid M. E., Fleuren, Emmy D. G., Versleijen-Jonkers, Yvonne M. H., van der Graaf, Winette T. A.

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Chimeric Antigen Receptor T cell Therapy and the Immunosuppressive Tumor Microenvironment in Pediatric Sarcoma von Terry, Rachael L., Meyran, Deborah, Fleuren, Emmy D. G., Mayoh, Chelsea, Zhu, Joe, Omer, Natacha, Ziegler, David S., Haber, Michelle, Darcy, Phillip K., Trapani, Joseph A., Neeson, Paul J., Ekert, Paul G.

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Targeting receptor tyrosine kinases in osteosarcoma and Ewing sarcoma: Current hurdles and future perspectives von Fleuren, Emmy D.G., Versleijen-Jonkers, Yvonne M.H., Boerman, Otto C., van der Graaf, Winette T.A.

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Temsirolimus combined with cisplatin or bevacizumab is active in osteosarcoma models von Fleuren, Emmy D.G., Versleijen‐Jonkers, Yvonne M.H., Roeffen, Melissa H.S., Franssen, Gerben M., Flucke, Uta E., Houghton, Peter J., Oyen, Wim J.G., Boerman, Otto C., Graaf, Winette T.A.

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Enhancing the Potential of Immunotherapy in Paediatric Sarcomas: Breaking the Immunosuppressive Barrier with Receptor Tyrosine Kinase Inhibitors von Fleuren, Emmy D G, Terry, Rachael L, Meyran, Deborah, Omer, Natacha, Trapani, Joseph A, Haber, Michelle, Neeson, Paul J, Ekert, Paul G

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Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness von Holme, Harriett, Gulati, Aditi, Brough, Rachel, Fleuren, Emmy D. G., Bajrami, Ilirjana, Campbell, James, Chong, Irene Y., Costa-Cabral, Sara, Elliott, Richard, Fenton, Tim, Frankum, Jessica, Jones, Samuel E., Menon, Malini, Miller, Rowan, Pemberton, Helen N., Postel-Vinay, Sophie, Rafiq, Rumana, Selfe, Joanna L., von Kriegsheim, Alex, Munoz, Amaya Garcia, Rodriguez, Javier, Shipley, Janet, van der Graaf, Winette T. A., Williamson, Chris T., Ryan, Colm J., Pettitt, Stephen, Ashworth, Alan, Strauss, Sandra J., Lord, Christopher J.

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