ABT-538 is a Potent Inhibitor of Human Immunodeficiency Virus Protease and has High Oral Bioavailability in Humans von Kempf, Dale J., Marsh, Kennan C., Denissen, Jon F., McDonald, Edith, Vasavanonda, Sudthida, Flentge, Charles A., Green, Brian E., Fino, Lynnmarie, Park, Chang H., Kong, Xiang-Peng, Wideburg, Norman E., Saldivar, Ayda, Ruiz, Lisa, Kati, Warren M., Sham, Hing L., Robins, Terry, Stewart, Kent D., Hsu, Ann, Plattner, Jacob J., Leonard, John M., Norbeck, Daniel W.

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Discovery of Ritonavir, a Potent Inhibitor of HIV Protease with High Oral Bioavailability and Clinical Efficacy von Kempf, Dale J, Sham, Hing L, Marsh, Kennan C, Flentge, Charles A, Betebenner, David, Green, Brian E, McDonald, Edith, Vasavanonda, Sudthida, Saldivar, Ayda, Wideburg, Norman E, Kati, Warren M, Ruiz, Lisa, Zhao, Chen, Fino, LynnMarie, Patterson, Jean, Molla, Akhteruzzaman, Plattner, Jacob J, Norbeck, Daniel W

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953 CHARACTERIZATION OF RESISTANCE MUTATIONS SELECTED IN VITRO BY THE NON-NUCLEOSIDE HCV POLYMERASE INHIBITORS ABT-333 AND ABT-072 von Koev, G, Mondal, R, Beyer, J, Reisch, T, Masse, S, Kati, W, Hutchinson, D, Flentge, C, Randolph, J, Donner, P, Krueger, A, Wagner, R, Yan, P, Lin, T, Maring, C, Molla, A

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955 PRECLINICAL POTENCY, PHARMACOKINETIC AND ADME CHARACTERIZATION OF ABT-333, A NOVEL NON-NUCLEOSIDE HCV POLYMERASE INHIBITOR von Maring, C, Wagner, R, Hutchinson, D, Flentge, C, Kati, W, Koev, G, Liu, Y, Beno, D, Shen, J, Lau, Y.Y, Gao, Y, Fischer, J, Vaidyanathan, S, Lim, B.H, Beyer, J, Mondal, R, Molla, A

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Oximinoarylsulfonamides as potent HIV protease inhibitors von Yeung, Clinton M., Klein, Larry L., Flentge, Charles A., Randolph, John T., Zhao, Chen, Sun, MingHua, Dekhtyar, Tatyana, Stoll, Vincent S., Kempf, Dale J.

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Lack of stereospecificity in the binding of the P2 amino acid of ritonavir to HIV protease von Kempf, Dale J., Molla, Akhteruzzaman, Marsh, Kennan C., Park, Chang, Rodrigues, A.David, Korneyeva, Marina, Vasavanonda, Sudthida, McDonald, Edith, Flentge, Charles A., Muchmore, Steven, Wideburg, Norman E., Saldivar, Ayda, Cooper, Art, Kati, Warren M., Stewart, Kent D., Norbeck, Daniel W.

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Evaluation of substituted benzamides as P2 ligands for symmetry-based inhibitors of HIV protease von Kempf, Dale J., Flentge, Charles A., Wideburg, Norman E., Saldivar, Ayda, Vasavanonda, Sudthida, Norbeck, Daniel W.

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Decomposition of solid peroxydisulfates von House, J.E., Flentge, Charles

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A study of propellant decomposition by differential scanning calorimetry von House, J.E., Flentge, Charles, Zack, Paul J.

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NOUVEAUX SELS DE THEOPHYLLINE 8-SUBSTITUEE UTILES COMME REACTIFS DANS DES DOSAGE IMMUNOLOGIQUE AVEC INHIBITEUR ENZYMATIQUE COMPETITIF IRREVERSIBLE von KIRKEMO C L, FLENTGE C A

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AGENTES ANTI-INFECCIOSOS CONTRA EL VIRUS HCV von HUANG, LEI, STEWART, K, PRATT, J, BETEBENNER, D, FLENTGE, C, LONGENECKER, K, MARING, C, TUFANO, M, HENGEVELD, J, BARNES, D, MOTTER, C, LIU, HUAQUING, ROCKWAY, T, FRANCZYK II, T, ZHANG, G, LIU, D, HENRY, R, DEGOEY, D, WAGNER, ROLF, GAO, JIAN, KRUEGER, A, LOU, X, SARRIS, K, DONNER, P, KATI, W, HUTCHINSON, D, CHEN, SHU-PING, RANDOLPH, J, HAIGHT, A, KOTECKI, B

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ANTI-INFECTIVE PYRIMIDINES AND USES THEREOF von RANDOLPH, JOHN, T. JT, FRANCZYK, THADDEUS, S., II TS, KATI, WARREN, M. WM, HENGEVELD, JOHN, E. JE, HUTCHINSON, DOUGLAS, K. DK, CHEN, SHUANG S, MOTTER, CHRISTOPHER, E. CE, PRATT, JOHN, K. JK, LOU, XIAOCHUN X, LONGENECKER, KENTON, L. KL, KOTECKI, BRIAN, J. BJ, FLENTGE, CHARLES, A. CA, KRUEGER, ALLAN, C. AC, BETEBENNER, DAVID, A. DA, HAIGHT, ANTHONY, R. AR, ZHANG, GEOFF, G., Z. GGZ, WAGNER, ROLF R, DONNER, PAMELA, L. PL, LIU, YAYA Y, MARING, CLARENCE, J. CJ, ROCKWAY, TODD, W. TW, BARNES, DAVID, M. DM, LIU, DACHUN D, STEWART, KENT, D. KD, DEGOEY, DAVID, A. DA, GAO, YI Y

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2-Pyridyl P1′-Substituted Symmetry-Based Human Immunodeficiency Virus Protease Inhibitors (A-792611 and A-790742) with Potential for Convenient Dosing and Reduced Side Effects von DeGoey, David A, Grampovnik, David J, Flentge, Charles A, Flosi, William J, Chen, Hui-ju, Yeung, Clinton M, Randolph, John T, Klein, Larry L, Dekhtyar, Tatyana, Colletti, Lynn, Marsh, Kennan C, Stoll, Vincent, Mamo, Mulugeta, Morfitt, David C, Nguyen, Bach, Schmidt, James M, Swanson, Sue J, Mo, Hongmei, Kati, Warren M, Molla, Akhteruzzaman, Kempf, Dale J

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Synthesis and evaluation of inhibitors of cytochrome P450 3A (CYP3A) for pharmacokinetic enhancement of drugs von Flentge, Charles A., Randolph, John T., Huang, Peggy P., Klein, Larry L., Marsh, Kennan C., Harlan, John E., Kempf, Dale J.

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Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors von Randolph, John T., Huang, Peggy P., Flosi, William J., DeGoey, David, Klein, Larry L., Yeung, Clinton M., Flentge, Charles, Sun, Mingua, Zhao, Chen, Dekhtyar, Tatyana, Mo, Hongmei, Colletti, Lynn, Kati, Warren, Marsh, Kennan C., Molla, Akhteruzzaman, Kempf, Dale J.

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Compuestos derivados de dihidropirimidina-2,4-(1h,3h)-diona; formas cristalinas, compuestos intermediarios; procedimiento de preparación de los compuestos intermediarios, composici... von MICHAEL D. TUFANO, KENT D. STEWART, TODD W. ROCKWAY, JOHN K. PRATT, BRIAN J. KOTECKI, ROLF WAGNER, CLARENCE J.MARING, KENTON L. LONGENECKER, KENTON L. LONGENECKER, YAYA LIU, DACHUN LIU, ALLAN C. KRUEGER, WARREN M. KATI, DOUGLAS K. HUTCHINSON, PEGGY P. HUANG, CHARLES A. FLENTGE, PAMELA L. DONNER, DAVID A. DeGOEY, DAVID A. BETEBENNER, DAVID M. BARNES, SHUANG CHEN, THADDEUS S.FRANCZYK II, YI GAO, ANTHONY R. HAIGHT, JOHN E. HENGEVELD, XIAOCHUN LOU, KATHY SARRIS, GEOFF G. Z. ZHANG, JOHN T. RANDOLPH, RODGER F. HENRY

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Anti-Viral Compounds von Sarris, Kathy, Wagaw, Seble H, Hutchins, Charles W, Carroll, William A, Li, Wenke, Randolph, John T, Jinkerson, Tammie K, Patel, Sachin V, Califano, Jean-Christophe C, Krueger, Allan C, Matulenko, Mark A, Betebenner, David A, Liu, Dachun, Tufano, Michael D, Kati, Warren M, Keddy, Ryan G, Flentge, Charles A, Maring, Clarence J, Bellizzi, Mary E, Pratt, John K, Hutchinson, Douglas K, Wagner, Rolf, Caspi, Daniel D, Rockway, Todd W, Donner, Pamela L, DeGoey, David A, Motter, Christopher E, Gao, Yi, Woller, Kevin R, Nelson, Lissa T

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HETEROCYCLIC COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS (HCV) von PATEL, SACHIN V, KEDDY, RYAN G, HUTCHINS, CHARLES W, LIU, DACHUN, DONNER, PAMELA L, RANDOLPH, JOHN T, ROCKWAY, TODD W, TUFANO, MICHAEL D, KATI, WARREN M, YI GAO, HUTCHINSON, DOUGLAS K, KRUEGER, ALLAN C, FLENTGE, CHARLES A, BETEBENNER, DAVID A, BELLIZZI, MARY E, JINKERSON, TAMMIE K, SARRIS, KATHY, MARING, CLARENCE J, WAGAW, SEBLE H, LI, WENKE, DEGOEY, DAVID A, WAGNER, ROLF, CALIFANO, JEAN C, CASPI, DANIEL D, WOLLER, KEVIN R, PRATT, JOHN K, NELSON, LISSA T, MOTTER, CHRISTOPHER E, MATULENKO, MARK A

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ANTI-VIRAL COMPOUNDS von HUTCHINS CHARLES W, WOLLER KEVIN R, BETEBENNER DAVID A, HUTCHINSON DOUGLAS K, ROCKWAY TODD W, FLENTGE CHARLES A, PATEL SACHIN V, SARRIS KATHY, JINKERSON TAMMIE K, GAO YI, DEGOEY DAVID A, KEDDY RYAN G, KATI WARREN M, MATULENKO MARK A, CALIFANO JEAN C, CASPI DANIEL D, MARING CLARENCE J, PRATT JOHN K, DONNER PAMELA L, NELSON LISSA T, WAGNER ROLF, RANDOLPH JOHN T, CARROLL WILLIAM A, TUFANO MICHAEL D, KRUEGER ALLAN C, MOTTER CHRISTOPHER E, LIU DACHUN, LI WENKE, WAGAW SEBLE H, BELLIZZI MARY E

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Towards a standardised cross-sector information exchange on present risk factors von Flentge, F, Beyel, C, Rome, E

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