Differential maturation and chaperone dependence of the paralogous protein kinases DYRK1A and DYRK1B von Papenfuss, Marco, Lützow, Svenja, Wilms, Gerrit, Babendreyer, Aaron, Flaßhoff, Maren, Kunick, Conrad, Becker, Walter

Volltext

A novel inhibitor rescues cerebellar defects in a zebrafish model of Down syndrome–associated kinase Dyrk1A overexpression von Buchberger, Astrid, Schepergerdes, Lena, Flaßhoff, Maren, Kunick, Conrad, Köster, Reinhard W.

Volltext

[ b ]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors von Lechner, Christian, Flaßhoff, Maren, Falke, Hannes, Preu, Lutz, Loaëc, Nadége, Meijer, Laurent, Knapp, Stefan, Chaikuad, Apirat, Kunick, Conrad

Volltext

Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S von Lategahn, Jonas, Keul, Marina, Klvekorn, Philip, Tumbrink, Hannah L, Niggenaber, Janina, Mller, Matthias P, Hodson, Luke, Flahoff, Maren, Hardick, Julia, Grabe, Tobias, Engel, Julian, Schultz-Fademrecht, Carsten, Baumann, Matthias, Ketzer, Julia, Mhlenberg, Thomas, Hiller, Wolf, Gnther, Georgia, Unger, Anke, Mller, Heiko, Heimsoeth, Alena, Golz, Christopher, Blank-Landeshammer, Bernhard, Kollipara, Laxmikanth, Zahedi, Ren P, Strohmann, Carsten, Hengstler, Jan G, van Otterlo, Willem A. L, Bauer, Sebastian, Rauh, Daniel

Volltext

A novel inhibitor rescues cerebellar defects in a zebrafish model of Down syndrome–associated kinase Dyrk1A overexpression von Buchberger, Astrid, Schepergerdes, Lena, Flaßhoff, Maren, Kunick, Conrad, Köster, Reinhard W.

Volltext

Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S† †Electronic supplementary information (ESI) available. CCDC 1876852. For ESI and crystallogra... von Lategahn, Jonas, Keul, Marina, Klövekorn, Philip, Tumbrink, Hannah L., Niggenaber, Janina, Müller, Matthias P., Hodson, Luke, Flaßhoff, Maren, Hardick, Julia, Grabe, Tobias, Engel, Julian, Schultz-Fademrecht, Carsten, Baumann, Matthias, Ketzer, Julia, Mühlenberg, Thomas, Hiller, Wolf, Günther, Georgia, Unger, Anke, Müller, Heiko, Heimsoeth, Alena, Golz, Christopher, Blank-Landeshammer, Bernhard, Kollipara, Laxmikanth, Zahedi, René P., Strohmann, Carsten, Hengstler, Jan G., van Otterlo, Willem A. L., Bauer, Sebastian, Rauh, Daniel

Volltext

Expanding the Chemical Space of Transforming Growth Factor‑β (TGFβ) Receptor Type II Degraders with 3,4-Disubstituted Indole Derivatives von Längle, Daniel, Wojtowicz-Piotrowski, Stephanie, Priegann, Till, Keller, Niklas, Wesseler, Fabian, Reckzeh, Elena S., Steffens, Karsten, Grathwol, Christoph, Lemke, Jana, Flasshoff, Maren, Näther, Christian, Jonson, Anna C., Link, Andreas, Koch, Oliver, Di Guglielmo, Gianni M., Schade, Dennis

Volltext