The CRTC1-SIK1 Pathway Regulates Entrainment of the Circadian Clock von Jagannath, Aarti, Butler, Rachel, Godinho, Sofia I.H., Couch, Yvonne, Brown, Laurence A., Vasudevan, Sridhar R., Flanagan, Kevin C., Anthony, Daniel, Churchill, Grant C., Wood, Matthew J.A., Steiner, Guido, Ebeling, Martin, Hossbach, Markus, Wettstein, Joseph G., Duffield, Giles E., Gatti, Silvia, Hankins, Mark W., Foster, Russell G., Peirson, Stuart N.

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Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis von Ruhland, Megan K., Loza, Andrew J., Capietto, Aude-Helene, Luo, Xianmin, Knolhoff, Brett L., Flanagan, Kevin C., Belt, Brian A., Alspach, Elise, Leahy, Kathleen, Luo, Jingqin, Schaffer, Andras, Edwards, John R., Longmore, Gregory, Faccio, Roberta, DeNardo, David G., Stewart, Sheila A.

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Analytical performance of OncoPrism-HNSCC, an RNA-based assay to inform immune checkpoint inhibitor treatment decisions for recurrent/metastatic head and neck squamous cell carcino... von Hiken, Jeffrey, Earls, Jon, Flanagan, Kevin C, Wellinghoff, Rachel L, Ponder, Michelle, Messina, David N, Glasscock, Jarret I, Duncavage, Eric J

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p38MAPK plays a crucial role in stromal-mediated tumorigenesis von Alspach, Elise, Flanagan, Kevin C, Luo, Xianmin, Ruhland, Megan K, Huang, Hui, Pazolli, Ermira, Donlin, Maureen J, Marsh, Timothy, Piwnica-Worms, David, Monahan, Joseph, Novack, Deborah V, McAllister, Sandra S, Stewart, Sheila A

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T cell subtype profiling measures exhaustion and predicts anti-PD-1 response von Schillebeeckx, Ian, Earls, Jon, Flanagan, Kevin C., Hiken, Jeffrey, Bode, Alex, Armstrong, Jon R., Messina, David N., Adkins, Douglas, Ley, Jessica, Alborelli, Ilaria, Jermann, Philip, Glasscock, Jarret I.

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Multidimensional biomarker predicts disease control in response to immunotherapy in recurrent or metastatic head and neck squamous-cell carcinoma von Flanagan, Kevin C., Earls, Jon, Schillebeeckx, Ian, Hiken, Jeffrey, Wellinghoff, Rachel L., LaFranzo, Natalie A., Bradley, Zachary S., Babbitt, Joey, Westra, William H., Hsu, Raymond, Nadauld, Lincoln, Mcleod, Howard, Firth, Sean D., Sharp, Brittany, Fuller, Josh, Vavinskaya, Vera, Sutton, Leisa, Deichaite, Ida, Bailey, Samuel D., Sandulache, Vlad C., Rendo, Matthew J., Macdonald, Orlan K., Welaya, Karim, Wade, James L., Pippas, Andrew W., Slim, Jennifer, Bank, Bruce, Saccaro, Steven J., Sui, Xingwei, Akhtar, Adil, Balaraman, Savitha, Kossman, Steven E., Sonnier, Scott A., Shenkenberg, Todd D., Alexander, Warren L., Price, Katherine A., Bane, Charles L., Ley, Jessica, Messina, David N., Glasscock, Jarret I., Cohen, Ezra E. W., Adkins, Douglas R., Duncavage, Eric J.

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CD4+ T cell and M2 macrophage infiltration predict dedifferentiated liposarcoma patient outcomes von Schroeder, Brett A, LaFranzo, Natalie A, LaFleur, Bonnie J, Gittelman, Rachel M, Vignali, Marissa, Zhang, Shihong, Flanagan, Kevin C, Rytlewski, Julie, Riolobos, Laura, Schulte, Brian C, Kim, Teresa S, Chen, Eleanor, Smythe, Kimberly S, Wagner, Michael J, Mantilla, Jose G, Campbell, Jean S, Pierce, Robert H, Jones, Robin L, Cranmer, Lee D, Pollack, Seth M

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Multicenter validation of an RNA-based assay to predict anti-PD-1 disease control in patients with recurrent or metastatic head and neck squamous cell carcinoma: the PREDAPT study von Flanagan, Kevin C, Earls, Jon, Hiken, Jeffrey, Wellinghoff, Rachel L, Ponder, Michelle M, McLeod, Howard L, Westra, William H, Vavinskaya, Vera, Sutton, Leisa, Deichaite, Ida, Macdonald, Orlan K, Welaya, Karim, Wade, James, Azzi, Georges, Pippas, Andrew W, Slim, Jennifer, Bank, Bruce, Sui, Xingwei, Kossman, Steven E, Shenkenberg, Todd D, Alexander, Warren L, Price, Katharine A, Ley, Jessica, Messina, David N, Glasscock, Jarret I, Colevas, A Dimitrios, Cohen, Ezra E W, Adkins, Douglas, Duncavage, Eric J

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Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss von Murali, Bhavna, Ren, Qihao, Luo, Xianmin, Faget, Douglas V, Wang, Chun, Johnson, Radia Marie, Gruosso, Tina, Flanagan, Kevin C, Fu, Yujie, Leahy, Kathleen, Alspach, Elise, Su, Xinming, Ross, Michael H, Burnette, Barry, Weilbaecher, Katherine N, Park, Morag, Mbalaviele, Gabriel, Monahan, Joseph B, Stewart, Sheila A

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Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice von Luyendyk, James P., Flanagan, Kevin C., Williams, C. David, Jaeschke, Hartmut, Slusser, Joyce G., Mackman, Nigel, Cantor, Glenn H.

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Predictive Immune Modeling of Solid Tumors von LaFranzo, Natalie A, Flanagan, Kevin C, Quintanilha, Danielle

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Neoadjuvant Therapy Induces a Potent Immune Response to Sarcoma, Dominated by Myeloid and B Cells von Goff, Peter H, Riolobos, Laura, LaFleur, Bonnie J, Spraker, Matthew B, Seo, Y David, Smythe, Kimberly S, Campbell, Jean S, Pierce, Robert H, Zhang, Yuzheng, He, Qianchuan, Kim, Edward Y, Schaub, Stephanie K, Kane, Gabrielle M, Mantilla, Jose G, Chen, Eleanor Y, Ricciotti, Robert, Thompson, Matthew J, Cranmer, Lee D, Wagner, Michael J, Loggers, Elizabeth T, Jones, Robin L, Murphy, Erin, Blumenschein, Wendy M, McClanahan, Terrill K, Earls, Jon, Flanagan, Kevin C, LaFranzo, Natalie A, Kim, Teresa S, Pollack, Seth M

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p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells von Nickless, Andrew, Cheruiyot, Abigael, Flanagan, Kevin C., Piwnica-Worms, David, Stewart, Sheila A., You, Zhongsheng

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c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors von Flanagan, Kevin C, Alspach, Elise, Pazolli, Ermira, Parajuli, Shankar, Ren, Qihao, Arthur, Laura L, Tapia, Roberto, Stewart, Sheila A

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Analytical Performance of an Immunoprofiling Assay Based on RNA Models von Schillebeeckx, Ian, Armstrong, Jon R., Forys, Jason T., Hiken, Jeffrey, Earls, Jon, Flanagan, Kevin C., Cui, Tiange, Glasscock, Jarret I., Messina, David N., Duncavage, Eric J.

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Abstract 3864: A single-center retrospective study of the immune landscape in patients with untreated liposarcoma (LS) with long-term follow-up von Schroeder, Brett A., LaFranzo, Natalie A., LaFleur, Bonnie J., Flanagan, Kevin C., Gittelman, Rachel M., Rytlewski, Julie, Pollack, Seth M.

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Predictive Immune Modeling of Solid Tumors von LaFranzo, Natalie A., Flanagan, Kevin C., Quintanilha, Danielle

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Additional file 4 of Analytical performance of OncoPrism-HNSCC, an RNA-based assay to inform immune checkpoint inhibitor treatment decisions for recurrent/metastatic head and neck... von Hiken, Jeffrey, Earls, Jon, Flanagan, Kevin C., Wellinghoff, Rachel L., Ponder, Michelle, Messina, David N., Glasscock, Jarret I., Duncavage, Eric J.

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Additional file 3 of Analytical performance of OncoPrism-HNSCC, an RNA-based assay to inform immune checkpoint inhibitor treatment decisions for recurrent/metastatic head and neck... von Hiken, Jeffrey, Earls, Jon, Flanagan, Kevin C., Wellinghoff, Rachel L., Ponder, Michelle, Messina, David N., Glasscock, Jarret I., Duncavage, Eric J.

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Additional file 2 of Analytical performance of OncoPrism-HNSCC, an RNA-based assay to inform immune checkpoint inhibitor treatment decisions for recurrent/metastatic head and neck... von Hiken, Jeffrey, Earls, Jon, Flanagan, Kevin C., Wellinghoff, Rachel L., Ponder, Michelle, Messina, David N., Glasscock, Jarret I., Duncavage, Eric J.

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