Calcium channel ITPR2 and mitochondria–ER contacts promote cellular senescence and aging von Ziegler, Dorian V., Vindrieux, David, Goehrig, Delphine, Jaber, Sara, Collin, Guillaume, Griveau, Audrey, Wiel, Clotilde, Bendridi, Nadia, Djebali, Sophia, Farfariello, Valerio, Prevarskaya, Natacha, Payen, Léa, Marvel, Jacqueline, Aubert, Sébastien, Flaman, Jean-Michel, Rieusset, Jennifer, Martin, Nadine, Bernard, David

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Revisiting Li-Fraumeni Syndrome From TP53 Mutation Carriers von Bougeard, Gaëlle, Renaux-Petel, Mariette, Flaman, Jean-Michel, Charbonnier, Camille, Fermey, Pierre, Belotti, Muriel, Gauthier-Villars, Marion, Stoppa-Lyonnet, Dominique, Consolino, Emilie, Brugières, Laurence, Caron, Olivier, Benusiglio, Patrick R, Bressac-de Paillerets, Brigitte, Bonadona, Valérie, Bonaïti-Pellié, Catherine, Tinat, Julie, Baert-Desurmont, Stéphanie, Frebourg, Thierry

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NF‐κB‐dependent secretome of senescent cells can trigger neuroendocrine transdifferentiation of breast cancer cells von Raynard, Clotilde, Ma, Xingjie, Huna, Anda, Tessier, Nolwenn, Massemin, Amélie, Zhu, Kexin, Flaman, Jean‐Michel, Moulin, Florentin, Goehrig, Delphine, Medard, Jean‐Jacques, Vindrieux, David, Treilleux, Isabelle, Hernandez‐Vargas, Hector, Ducreux, Sylvie, Martin, Nadine, Bernard, David

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Loss of Pla2r1 decreases cellular senescence and age‐related alterations caused by aging and Western diets von Massemin, Amélie, Goehrig, Delphine, Flaman, Jean‐Michel, Jaber, Sara, Griveau, Audrey, Djebali, Sophia, Marcos, Elisabeth, Payen, Léa, Marvel, Jacqueline, Parent, Romain, Adnot, Serge, Bertolino, Philippe, Rieusset, Jennifer, Tortereau, Antonin, Vindrieux, David, Bernard, David

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Transformed cells after senescence give rise to more severe tumor phenotypes than transformed non-senescent cells von Palazzo, Alberta, Hernandez-Vargas, Hector, Goehrig, Delphine, Médard, Jean-Jacques, Vindrieux, David, Flaman, Jean-Michel, Bernard, David

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Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A von Zhao, Yajie, Wu, Zhichong, Chanal, Marie, Guillaumond, Fabienne, Goehrig, Delphine, Bachy, Sophie, Principe, Moitza, Ziverec, Audrey, Flaman, Jean-Michel, Collin, Guillaume, Tomasini, Richard, Pasternack, Arja, Ritvos, Olli, Vasseur, Sophie, Bernard, David, Hennino, Ana, Bertolino, Philippe

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The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway von Warnier, Marine, Flaman, Jean‐Michel, Chouabe, Christophe, Wiel, Clotilde, Gras, Baptiste, Griveau, Audrey, Blanc, Elena, Foy, Jean‐Philippe, Mathot, Pauline, Saintigny, Pierre, Van Coppenolle, Fabien, Vindrieux, David, Martin, Nadine, Bernard, David

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PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging von Huna, Anda, Griveau, Audrey, Vindrieux, David, Jaber, Sara, Flaman, Jean-Michel, Goehrig, Delphine, Azzi, Lamia, Médard, Jean-Jacques, Djebali, Sophia, Hernandez-Vargas, Hector, Dante, Robert, Payen, Léa, Marvel, Jacqueline, Bertolino, Philippe, Aubert, Sébastien, Dubus, Pierre, Bernard, David

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RSK3 switches cell fate: from stress-induced senescence to malignant progression von Huna, Anda, Flaman, Jean-Michel, Lodillinsky, Catalina, Zhu, Kexin, Makulyte, Gabriela, Pakulska, Victoria, Coute, Yohann, Ruisseaux, Clémence, Saintigny, Pierre, Hernandez-Vargas, Hector, Defossez, Pierre-Antoine, Boissan, Mathieu, Martin, Nadine, Bernard, David

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A non-canonical role of ELN protects from cellular senescence by limiting iron-dependent regulation of gene expression von Czarnecka-Herok, Joanna, Zhu, Kexin, Flaman, Jean-Michel, Goehrig, Delphine, Vernier, Mathieu, Makulyte, Gabriela, Lamboux, Aline, Dragic, Helena, Rhinn, Muriel, Médard, Jean-Jacques, Faury, Gilles, Bertolino, Philippe, Balter, Vincent, Debret, Romain, Adnot, Serge, Martin, Nadine, Bernard, David

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Role of the LytSR Two-Component Regulatory System in Staphylococcus lugdunensis Biofilm Formation and Pathogenesis von Dahyot, Sandrine, Oxaran, Virginie, Niepceron, Maite, Dupart, Eddy, Legris, Stephanie, Destruel, Laurie, Didi, Jennifer, Clamens, Thomas, Lesouhaitier, Olivier, Zerdoumi, Yasmine, Flaman, Jean-Michel, Pestel-Caron, Martine

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PACAP Protects the Adolescent and Adult Mice Brain from Ethanol Toxicity and Modulates Distinct Sets of Genes Regulating Similar Networks von Lacaille, Hélène, Duterte-Boucher, Dominique, Vaudry, Hubert, Zerdoumi, Yasmine, Flaman, Jean-Michel, Hashimoto, Hitoshi, Vaudry, David

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Drastic Effect of Germline TP53 Missense Mutations in Li-Fraumeni Patients von Zerdoumi, Yasmine, Aury-Landas, Juliette, Bonaïti-Pellié, Catherine, Derambure, Céline, Sesboüé, Richard, Renaux-Petel, Mariette, Frebourg, Thierry, Bougeard, Gaëlle, Flaman, Jean-Michel

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Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression von Born, Emmanuelle, Lipskaia, Larissa, Breau, Marielle, Houssaini, Amal, Beaulieu, Delphine, Marcos, Elisabeth, Pierre, Remi, Do Cruzeiro, Marcio, Lefevre, Marine, Derumeaux, Genevieve, Bulavin, Dmitry V., Delcroix, Marion, Quarck, Rozenn, Reen, Virinder, Gil, Jesus, Bernard, David, Flaman, Jean-Michel, Adnot, Serge, Abid, Shariq

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Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence von Collin, Guillaume, Huna, Anda, Warnier, Marine, Flaman, Jean-Michel, Bernard, David

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Evidence That SARS-CoV-2 Induces Lung Cell Senescence: Potential Impact on COVID-19 Lung Disease von Lipskaia, Larissa, Maisonnasse, Pauline, Fouillade, Charles, Sencio, Valentin, Pascal, Quentin, Flaman, Jean-Michel, Born, Emmanuelle, Londono-Vallejo, Arturo, Le Grand, Roger, Bernard, David, Trottein, François, Adnot, Serge

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Contribution of genotoxic anticancer treatments to the development of multiple primary tumours in the context of germline TP53 mutations von Kasper, Edwige, Angot, Emilie, Colasse, Elodie, Nicol, Lionel, Sabourin, Jean-Christophe, Adriouch, Sahil, Lacoume, Yann, Charbonnier, Camille, Raad, Sabine, Frebourg, Thierry, Flaman, Jean-Michel, Bougeard, Gaëlle

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Germline TP53 mutations result into a constitutive defect of p53 DNA binding and transcriptional response to DNA damage von Zerdoumi, Yasmine, Lanos, Raphaël, Raad, Sabine, Flaman, Jean-Michel, Bougeard, Gaëlle, Frebourg, Thierry, Tournier, Isabelle

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Expression of the Calcium-Binding Protein CALB1 Is Induced and Controls Intracellular Ca2+ Levels in Senescent Cells von Raynard, Clotilde, Tessier, Nolwenn, Huna, Anda, Warnier, Marine, Flaman, Jean-Michel, Van Coppenolle, Fabien, Ducreux, Sylvie, Martin, Nadine, Bernard, David

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Inactivation of the RRB1-Pescadillo pathway involved in ribosome biogenesis induces chromosomal instability von KILLIAN, Audrey, LE MEUR, Nathalie, SESBOÜE, Richard, BOURGUIGNON, Jeannette, BOUGEARD, Gaëlle, GAUTHEROT, Julien, BASTARD, Christian, FREBOURG, Thierry, FLAMAN, Jean-Michel

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