The Conserved Misshapen-Warts-Yorkie Pathway Acts in Enteroblasts to Regulate Intestinal Stem Cells in Drosophila von Li, Qi, Li, Shuangxi, Mana-Capelli, Sebastian, Roth Flach, Rachel J., Danai, Laura V., Amcheslavsky, Alla, Nie, Yingchao, Kaneko, Satoshi, Yao, Xiaohao, Chen, Xiaochu, Cotton, Jennifer L., Mao, Junhao, McCollum, Dannel, Jiang, Jin, Czech, Michael P., Xu, Lan, Ip, Y. Tony

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IL-1 signaling in obesity-induced hepatic lipogenesis and steatosis von Negrin, Kimberly A, Roth Flach, Rachel J, DiStefano, Marina T, Matevossian, Anouch, Friedline, Randall H, Jung, DaeYoung, Kim, Jason K, Czech, Michael P

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Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition von Roth Flach, Rachel J, Su, Chunyan, Bollinger, Eliza, Cortes, Christian, Robertson, Andrew W, Opsahl, Alan C, Coskran, Timothy M, Maresca, Kevin P, Keliher, Edmund J, Yates, Phillip D, Kim, Albert M, Kalgutkar, Amit S, Buckbinder, Leonard

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Hepatic Mitogen-Activated Protein Kinase Phosphatase 1 Selectively Regulates Glucose Metabolism and Energy Homeostasis von Lawan, Ahmed, Zhang, Lei, Gatzke, Florian, Min, Kisuk, Jurczak, Michael J., Al-Mutairi, Mashael, Richter, Patric, Camporez, Joao Paulo G., Couvillon, Anthony, Pesta, Dominik, Roth Flach, Rachel J., Shulman, Gerald I., Bennett, Anton M.

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Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels von Roth Flach, Rachel J., Bollinger, Eliza, Reyes, Allan R., Laforest, Brigitte, Kormos, Bethany L., Liu, Shenping, Reese, Matthew R., Martinez Alsina, Luis A., Buzon, Leanne, Zhang, Yuan, Bechle, Bruce, Rosado, Amy, Sahasrabudhe, Parag V., Knafels, John, Bhattacharya, Samit K., Omoto, Kiyoyuki, Stansfield, John C., Hurley, Liam D., Song, LouJin, Luo, Lina, Breitkopf, Susanne B., Monetti, Mara, Cunio, Teresa, Tierney, Brendan, Geoly, Frank J., Delmore, Jake, Siddall, C. Parker, Xue, Liang, Yip, Ka N., Kalgutkar, Amit S., Miller, Russell A., Zhang, Bei B., Filipski, Kevin J.

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Targeting lymphatic function in cardiovascular-kidney-metabolic syndrome: preclinical methods to analyze lymphatic function and therapeutic opportunities von Fowler, Joseph Wayne M, Song, LouJin, Tam, Kelly, Roth Flach, Rachel J

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β3-Adrenergic Receptor Stimulation Induces E-Selectin-mediated Adipose Tissue Inflammation von Roth Flach, Rachel J., Matevossian, Anouch, Akie, Thomas E., Negrin, Kimberly A., Paul, Marina T., Czech, Michael P.

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Identification of Map4k4 as a Novel Suppressor of Skeletal Muscle Differentiation von Wang, Mengxi, Amano, Shinya U., Flach, Rachel J. Roth, Chawla, Anil, Aouadi, Myriam, Czech, Michael P.

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NETs and traps delay wound healing in diabetes von Roth Flach, Rachel J, Czech, Michael P

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The Lipid Droplet Protein Hypoxia-inducible Gene 2 Promotes Hepatic Triglyceride Deposition by Inhibiting Lipolysis von DiStefano, Marina T., Danai, Laura V., Roth Flach, Rachel J., Chawla, Anil, Pedersen, David J., Guilherme, Adilson, Czech, Michael P.

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Lymphangiogenic therapy prevents cardiac dysfunction by ameliorating inflammation and hypertension von Song, LouJin, Chen, Xian, Swanson, Terri A., LaViolette, Brianna, Pang, Jincheng, Cunio, Teresa, Nagle, Michael W., Asano, Shoh, Hales, Katherine, Shipstone, Arun, Sobon, Hanna, Al-Harthy, Sabra D., Ahn, Youngwook, Kreuser, Steven, Robertson, Andrew, Ritenour, Casey, Voigt, Frank, Boucher, Magalie, Sun, Furong, Sessa, William C., Flach, Rachel J. Roth

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Discovery of First Branched-Chain Ketoacid Dehydrogenase Kinase (BDK) Inhibitor Clinical Candidate PF-07328948 von Filipski, Kevin J, Martinez-Alsina, Luis A, Reese, Matthew R, Evrard, Edelweiss, Buzon, Leanne M, Cameron, Kimberly O, Zhang, Yuan, Coffman, Karen J, Bradow, James, Kormos, Bethany L, Liu, Shenping, Knafels, John D, Sahasrabudhe, Parag V, Chen, Jie, Kalgutkar, Amit S, Bessire, Andrew J, Orozco, Christine C, Balesano, Amanda, Cerny, Matthew A, Bollinger, Eliza, Reyes, Allan R, Laforest, Brigitte, Rosado, Amy, Williams, George, Marshall, Mackenzie, Tam Neale, Kelly, Chen, Xian, Hirenallur-Shanthappa, Dinesh, Stansfield, John C, Groarke, John, Qiu, Ruolun, Karas, Spinel, Roth Flach, Rachel J, Esler, William P

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Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function von Roth Flach, Rachel J., Guo, Chang-An, Danai, Laura V., Yawe, Joseph C., Gujja, Sharvari, Edwards, Yvonne J. K., Czech, Michael P.

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Map4k4 impairs energy metabolism in endothelial cells and promotes insulin resistance in obesity von Roth Flach, Rachel J, DiStefano, Marina T, Danai, Laura V, Senol-Cosar, Ozlem, Yawe, Joseph C, Kelly, Mark, Garcia Menendez, Lorena, Czech, Michael P

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Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia von Roth Flach, Rachel J., Danai, Laura V., DiStefano, Marina T., Kelly, Mark, Menendez, Lorena Garcia, Jurczyk, Agata, Sharma, Rohit B., Jung, Dae Young, Kim, Jong Hun, Kim, Jason K., Bortell, Rita, Alonso, Laura C., Czech, Michael P.

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Peripartum Cardiomyopathy: Is It All in the Timing? von Roth Flach, Rachel J., Khankin, Eliyahu V.

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Branched-chain amino acid catabolism in muscle affects systemic BCAA levels but not insulin resistance von Blair, Megan C., Neinast, Michael D., Jang, Cholsoon, Chu, Qingwei, Jung, Jae Woo, Axsom, Jessie, Bornstein, Marc R., Thorsheim, Chelsea, Li, Kristina, Hoshino, Atsushi, Yang, Steven, Roth Flach, Rachel J., Zhang, Bei B., Rabinowitz, Joshua D., Arany, Zoltan

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Abstract 12466: Targeted Quantitative Plasma Metabolomics Identifies Metabolite Signatures That Distinguish Heart Failure With Reduced and Preserved Ejection Fraction von Naeem, Fawaz, Leone, Teresa, Petucci, Christopher, Groarke, John D, Bennett, Donald, Mancuso, Jessica, Tzameli, Iphigenia, Roth Flach, Rachel J, Rader, Daniel J, Kelly, Daniel P

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Abstract 15241: Mixed Meal Tolerance Test Elicits Distinct Metabolite Kinetics for Individuals With and Without Diabetes von Mi, Michael Y, Whitlock, Mark, shi, xu, Farrell, Laurie A, Bhambhani, Victoria M, Quadir, Juweria, Blatnik, Matthew, Wald, Kyle P, Tierney, Brendan, Kim, Albert, loudon, peter, Chen, Zsu-Zsu, Roth Flach, Rachel J, Gerszten, Robert E

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Abstract 644: Enhancing Lymphangiogenesis Ameliorates Chronic Heart Failure von Song, Loujin, Swanson, Terri, Chen, Xian, Cunio, Teresa, LaViolette, Brianna, Asano, Shoh, Hales, Katherine, Pang, Jincheng, Robertson, Andrew, Ritenour, Casey, Boucher, Magalie, Roth Flach, Rachel J

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