Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal von Turajlic, Samra, Xu, Hang, Litchfield, Kevin, Rowan, Andrew, Horswell, Stuart, Chambers, Tim, O’Brien, Tim, Lopez, Jose I., Watkins, Thomas B.K., Nicol, David, Stares, Mark, Challacombe, Ben, Hazell, Steve, Chandra, Ashish, Mitchell, Thomas J., Au, Lewis, Eichler-Jonsson, Claudia, Jabbar, Faiz, Soultati, Aspasia, Chowdhury, Simon, Rudman, Sarah, Lynch, Joanna, Fernando, Archana, Stamp, Gordon, Nye, Emma, Stewart, Aengus, Xing, Wei, Smith, Jonathan C., Escudero, Mickael, Huffman, Adam, Matthews, Nik, Elgar, Greg, Phillimore, Ben, Costa, Marta, Begum, Sharmin, Ward, Sophia, Salm, Max, Boeing, Stefan, Fisher, Rosalie, Spain, Lavinia, Navas, Carolina, Grönroos, Eva, Hobor, Sebastijan, Sharma, Sarkhara, Aurangzeb, Ismaeel, Lall, Sharanpreet, Polson, Alexander, Varia, Mary, Horsfield, Catherine, Fotiadis, Nicos, Pickering, Lisa, Schwarz, Roland F., Silva, Bruno, Herrero, Javier, Luscombe, Nick M., Jamal-Hanjani, Mariam, Rosenthal, Rachel, Birkbak, Nicolai J., Wilson, Gareth A., Pipek, Orsolya, Ribli, Dezso, Krzystanek, Marcin, Csabai, Istvan, Szallasi, Zoltan, Gore, Martin, McGranahan, Nicholas, Van Loo, Peter, Campbell, Peter, Larkin, James, Swanton, Charles

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Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing von Gerlinger, Marco, Horswell, Stuart, Larkin, James, Rowan, Andrew J, Salm, Max P, Varela, Ignacio, Fisher, Rosalie, McGranahan, Nicholas, Matthews, Nicholas, Santos, Claudio R, Martinez, Pierre, Phillimore, Benjamin, Begum, Sharmin, Rabinowitz, Adam, Spencer-Dene, Bradley, Gulati, Sakshi, Bates, Paul A, Stamp, Gordon, Pickering, Lisa, Gore, Martin, Nicol, David L, Hazell, Steven, Futreal, P Andrew, Stewart, Aengus, Swanton, Charles

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Targeted therapy and immunotherapy in advanced melanoma: an evolving paradigm von Khattak, Muhammad, Fisher, Rosalie, Turajlic, Samra, Larkin, James

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Metastatic mucinous tubular and spindle cell carcinoma of the kidney responding to sunitinib von Larkin, James, Fisher, Rosalie, Pickering, Lisa, Thway, Khin, Livni, Naomi, Fisher, Cyril, Gore, Martin

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Inter and intratumour heterogeneity: a barrier to individualized medical therapy in renal cell carcinoma? von Fisher, Rosalie, Larkin, James, Swanton, Charles

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Current and future systemic treatments for renal cell carcinoma von Fisher, Rosalie, Gore, Martin, Larkin, James

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Mixed Messages: I. The Consequences of Communicating Negative Statements Within Emotional Support Messages to Cancer Patients von Ray, Colter D, Floyd, Kory, Tietsort, Cris J, Veluscek, Alaina M, Otmar, Christopher D, Hashi, Emi C, Fisher, Rosalie

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Chromophobe renal cell carcinoma with prolonged response to sequential sunitinib and everolimus von Larkin, James M G, Fisher, Rosalie A, Pickering, Lisa M, Sohaib, S Aslam, Ghosn, Marwan, Christmas, Tim, Cordiner, Ruth L M, Gore, Martin E

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Endobronchial metastases from renal cell carcinoma: A late manifestation of the disease with an increasing incidence von Khattak, Muhammad A., Fisher, Rosalie A., Pickering, Lisa M., Gore, Martin E., Larkin, James M.

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Combined BRAF and MEK inhibition with PD-1 blockade immunotherapy in BRAF-mutant melanoma von Ribas, Antoni, Lawrence, Donald, Atkinson, Victoria, Agarwal, Sachin, Miller, Wilson H., Carlino, Matteo S., Fisher, Rosalie, Long, Georgina V., Hodi, F. Stephen, Tsoi, Jennifer, Grasso, Catherine S., Mookerjee, Bijoyesh, Zhao, Qing, Ghori, Razi, Moreno, Blanca Homet, Ibrahim, Nageatte, Hamid, Omid

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Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma von Ascierto, Paolo Antonio, Ferrucci, Pier Francesco, Fisher, Rosalie, Del Vecchio, Michele, Atkinson, Victoria, Schmidt, Henrik, Schachter, Jacob, Queirolo, Paola, Long, Georgina V., Di Giacomo, Anna Maria, Svane, Inge Marie, Lotem, Michal, Bar-Sela, Gil, Couture, Felix, Mookerjee, Bijoyesh, Ghori, Razi, Ibrahim, Nageatte, Moreno, Blanca Homet, Ribas, Antoni

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Treatment of brain metastases in patients with melanoma von Fisher, Rosalie, Larkin, James

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Subsidised access to new melanoma drugs : in need of further innovation? von Fisher, Rosalie, Wonder, Michael

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Malignant melanoma (metastatic) von Fisher, Rosalie Anne, Larkin, James

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Revised Choi imaging criteria correlate with clinical outcomes in patients with metastatic renal cell carcinoma treated with sunitinib von Thian, Yeeliang, Gutzeit, Andreas, Koh, Dow-Mu, Fisher, Rosalie, Lote, Hazel, Larkin, James, Sohaib, Aslam

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Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution von Kovac, Michal, Navas, Carolina, Horswell, Stuart, Salm, Max, Bardella, Chiara, Rowan, Andrew, Stares, Mark, Castro-Giner, Francesc, Fisher, Rosalie, de Bruin, Elza C., Kovacova, Monika, Gorman, Maggie, Makino, Seiko, Williams, Jennet, Jaeger, Emma, Jones, Angela, Howarth, Kimberley, Larkin, James, Pickering, Lisa, Gore, Martin, Nicol, David L., Hazell, Steven, Stamp, Gordon, O’Brien, Tim, Challacombe, Ben, Matthews, Nik, Phillimore, Benjamin, Begum, Sharmin, Rabinowitz, Adam, Varela, Ignacio, Chandra, Ashish, Horsfield, Catherine, Polson, Alexander, Tran, Maxine, Bhatt, Rupesh, Terracciano, Luigi, Eppenberger-Castori, Serenella, Protheroe, Andrew, Maher, Eamonn, El Bahrawy, Mona, Fleming, Stewart, Ratcliffe, Peter, Heinimann, Karl, Swanton, Charles, Tomlinson, Ian

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Parallel evolution of tumour subclones mimics diversity between tumours von Martinez, Pierre, Birkbak, Nicolai Juul, Gerlinger, Marco, McGranahan, Nicholas, Burrell, Rebecca A, Rowan, Andrew J, Joshi, Tejal, Fisher, Rosalie, Larkin, James, Szallasi, Zoltan, Swanton, Charles

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Crossover and rechallenge with pembrolizumab in recurrent patients from the EORTC 1325-MG/Keynote-054 phase III trial, pembrolizumab versus placebo after complete resection of high... von Eggermont, Alexander MM, Meshcheryakov, Andrey, Atkinson, Victoria, Blank, Christian U., Mandala, Mario, Long, Georgina V., Barrow, Catherine, Di Giacomo, Anna Maria, Fisher, Rosalie, Sandhu, Shahneen, Kudchadkar, Ragini, Ortiz Romero, Pablo Luis, Svane, Inge Marie, Larkin, James, Puig, Susana, Hersey, Peter, Quaglino, Pietro, Queirolo, Paola, Stroyakovskiy, Daniil, Bastholt, Lars, Mohr, Peter, Hernberg, Micaela, Chiarion-Sileni, Vanna, Strother, Matthew, Hauschild, Axel, Yamazaki, Naoya, van Akkooi, Alexander CJ, Lorigan, Paul, Krepler, Clemens, Ibrahim, Nageatte, Marreaud, Sandrine, Kicinski, Michal, Suciu, Stefan, Robert, Caroline

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Vemurafenib: a new treatment for BRAF-V600 mutated advanced melanoma von Fisher, Rosalie, Larkin, James

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Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas von Gerlinger, Marco, Quezada, Sergio A, Peggs, Karl S, Furness, Andrew JS, Fisher, Rosalie, Marafioti, Teresa, Shende, Vishvesh H, McGranahan, Nicholas, Rowan, Andrew J, Hazell, Steven, Hamm, David, Robins, Harlan S, Pickering, Lisa, Gore, Martin, Nicol, David L, Larkin, James, Swanton, Charles

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