A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome von Wiseman, Frances K., Al-Janabi, Tamara, Hardy, John, Karmiloff-Smith, Annette, Nizetic, Dean, Tybulewicz, Victor L. J., Fisher, Elizabeth M. C., Strydom, André

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Is SOD1 loss of function involved in amyotrophic lateral sclerosis? von SACCON, Rachele A, BUNTON-STASYSHYN, Rosie K. A, FISHER, Elizabeth M. C, FRATTA, Pietro

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Recent introduction of a chytrid fungus endangers Western Palearctic salamanders von Martel, A., Blooi, M., Adriaensen, C., Van Rooij, P., Beukema, W., Fisher, M. C., Farrer, R. A., Schmidt, B. R., Tobler, U., Goka, K., Lips, K. R., Muletz, C., Zamudio, K. R., Bosch, J., Lötters, S., Wombwell, E., Garner, T. W. J., Cunningham, A. A., Spitzen-van der Sluijs, A., Salvidio, S., Ducatelle, R., Nishikawa, K., Nguyen, T. T., Kolby, J. E., Van Bocxlaer, I., Bossuyt, F., Pasmans, F.

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Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia von Fratta, Pietro, Poulter, Mark, Lashley, Tammaryn, Rohrer, Jonathan D., Polke, James M., Beck, Jon, Ryan, Natalie, Hensman, Davina, Mizielinska, Sarah, Waite, Adrian J., Lai, Mang-Ching, Gendron, Tania F., Petrucelli, Leonard, Fisher, Elizabeth M. C., Revesz, Tamas, Warren, Jason D., Collinge, John, Isaacs, Adrian M., Mead, Simon

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Humanising the mouse genome piece by piece von Zhu, Fei, Nair, Remya R., Fisher, Elizabeth M. C., Cunningham, Thomas J.

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Species-Specific Transcription in Mice Carrying Human Chromosome 21 von Wilson, Michael D, Barbosa-Morais, Nuno L, Schmidt, Dominic, Conboy, Caitlin M, Vanes, Lesley, Tybulewicz, Victor L.J, Fisher, Elizabeth M.C, Tavaré, Simon, Odom, Duncan T

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SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments von Joyce, Peter I., Fratta, Pietro, Fisher, Elizabeth M. C., Acevedo-Arozena, Abraham

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Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome von Cannavo, Claudia, Cleverley, Karen, Maduro, Cheryl, Mumford, Paige, Moulding, Dale, Fisher, Elizabeth M C, Wiseman, Frances K

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Genetic analysis of the cytoplasmic dynein subunit families von Pfister, K Kevin, Shah, Paresh R, Hummerich, Holger, Russ, Andreas, Cotton, James, Annuar, Azlina Ahmad, King, Stephen M, Fisher, Elizabeth M C

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Correlation of clinical and molecular features in spinal bulbar muscular atrophy von Fratta, Pietro, Nirmalananthan, Niranjanan, Masset, Luc, Skorupinska, Iwona, Collins, Toby, Cortese, Andrea, Pemble, Sally, Malaspina, Andrea, Fisher, Elizabeth M.C, Greensmith, Linda, Hanna, Michael G

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point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice von Becker, Esther B.E, Oliver, Peter L, Glitsch, Maike D, Banks, Gareth T, Achilli, Francesca, Hardy, Andrea, Nolan, Patrick M, Fisher, Elizabeth M.C, Davies, Kay E

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Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia von Sørensen, Sven Asger, Gade, Anders, Lloyd, Sarah L, Spillantini, Maria Grazia, Hodges, John R, Johannsen, Peter, Parkinson, Nicholas J, Hummerich, Holger, Gydesen, Susanne, Chakrabarti, Lisa, Brun, Arne, Brown, Jeremy M, Brandner, Sebastian, Collinge, John, Skibinski, Gaia, Rossor, Martin N, Fisher, Elizabeth MC, Nielsen, Jørgen E, Thusgaard, Tove

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Aneuploid Mouse Strain Carrying Human Chromosome 21 with Down Syndrome Phenotypes von O'Doherty, Aideen, Ruf, Sandra, Mulligan, Claire, Hildreth, Victoria, Errington, Mick L, Cooke, Sam, Sesay, Abdul, Modino, Sonie, Vanes, Lesley, Hernandez, Diana, Linehan, Jacqueline M, Sharpe, Paul T, Brandner, Sebastian, Bliss, Timothy V. P, Henderson, Deborah J, Nizetic, Dean, Tybulewicz, Victor L. J, Fisher, Elizabeth M. C

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Down syndrome—recent progress and future prospects von Wiseman, Frances K., Alford, Kate A., Tybulewicz, Victor L.J., Fisher, Elizabeth M.C.

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ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B) von PARKINSON, N, INCE, P. G, SHAW, P. J, FISHER, E. M. C, SMITH, M. O, HIGHLEY, R, SKIBINSKI, G, ANDERSEN, P. M, MORRISON, K. E, PALL, H. S, HARDIMAN, O, COLLINGE, J

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Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration von Watson-Scales, Sheona, Kalmar, Bernadett, Lana-Elola, Eva, Gibbins, Dorota, La Russa, Federica, Wiseman, Frances, Williamson, Matthew, Saccon, Rachele, Slender, Amy, Olerinyova, Anna, Mahmood, Radma, Nye, Emma, Cater, Heather, Wells, Sara, Yu, Y Eugene, Bennett, David L H, Greensmith, Linda, Fisher, Elizabeth M C, Tybulewicz, Victor L J

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Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice von GHAZI-NOORI, Shabnam, FROUD, Kristina E, ASANTE, Emmanuel A, BRANDNER, Sebastian, COLLINGE, John, ISAACS, Adrian M, MIZIELINSKA, Sarah, POWELL, Caroline, SMIDAK, Michelle, DE MARCO, Mar Fernandez, O'MALLEY, Catherine, FARMER, Michael, PARKINSON, Nick, FISHER, Elizabeth M. C

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Rodent models in Down syndrome research: impact and future opportunities von Herault, Yann, Delabar, Jean M, Fisher, Elizabeth M C, Tybulewicz, Victor L J, Yu, Eugene, Brault, Veronique

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Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome von Gribble, Susan M, Wiseman, Frances K, Clayton, Stephen, Prigmore, Elena, Langley, Elizabeth, Yang, Fengtang, Maguire, Sean, Fu, Beiyuan, Rajan, Diana, Sheppard, Olivia, Scott, Carol, Hauser, Heidi, Stephens, Philip J, Stebbings, Lucy A, Ng, Bee Ling, Fitzgerald, Tomas, Quail, Michael A, Banerjee, Ruby, Rothkamm, Kai, Tybulewicz, Victor L J, Fisher, Elizabeth M C, Carter, Nigel P

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Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations von Urwin, Hazel, Authier, Astrid, Nielsen, Jorgen E., Metcalf, Daniel, Powell, Caroline, Froud, Kristina, Malcolm, Denise S., Holm, Ida, Johannsen, Peter, Brown, Jeremy, Fisher, Elizabeth M.C., van der Zee, Julie, Bruyland, Marc, Van Broeckhoven, Christine, Collinge, John, Brandner, Sebastian, Futter, Clare, Isaacs, Adrian M.

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