From somatic mutation to early detection: insights from molecular characterization of pancreatic cancer precursor lesions von Fischer, Catherine G, Wood, Laura D

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The 2019 US medical genetics workforce: a focus on clinical genetics von Jenkins, Brittany D., Fischer, Catherine G., Polito, Curt A., Maiese, Deborah R., Keehn, Alisha S., Lyon, Megan, Edick, Mathew J., Taylor, Matthew R.G., Andersson, Hans C., Bodurtha, Joann N., Blitzer, Miriam G., Muenke, Maximilian, Watson, Michael S.

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IPMNs with co-occurring invasive cancers: neighbours but not always relatives von Felsenstein, Matthäus, Noë, Michaël, Masica, David L, Hosoda, Waki, Chianchiano, Peter, Fischer, Catherine G, Lionheart, Gemma, Brosens, Lodewijk A A, Pea, Antonio, Yu, Jun, Gemenetzis, Georgios, Groot, Vincent P, Makary, Martin A, He, Jin, Weiss, Matthew J, Cameron, John L, Wolfgang, Christopher L, Hruban, Ralph H, Roberts, Nicholas J, Karchin, Rachel, Goggins, Michael G, Wood, Laura D

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Intraductal Papillary Mucinous Neoplasms Arise From Multiple Independent Clones, Each With Distinct Mutations von Fischer, Catherine G., Beleva Guthrie, Violeta, Braxton, Alicia M., Zheng, Lily, Wang, Pei, Song, Qianqian, Griffin, James F., Chianchiano, Peter E., Hosoda, Waki, Niknafs, Noushin, Springer, Simeon, Dal Molin, Marco, Masica, David, Scharpf, Robert B., Thompson, Elizabeth D., He, Jin, Wolfgang, Christopher L., Hruban, Ralph H., Roberts, Nicholas J., Lennon, Anne Marie, Jiao, Yuchen, Karchin, Rachel, Wood, Laura D.

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Single‐cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions von Kuboki, Yuko, Fischer, Catherine G, Beleva Guthrie, Violeta, Huang, Wenjie, Yu, Jun, Chianchiano, Peter, Hosoda, Waki, Zhang, Hao, Zheng, Lily, Shao, Xiaoshan, Thompson, Elizabeth D, Waters, Kevin, Poling, Justin, He, Jin, Weiss, Matthew J, Wolfgang, Christopher L, Goggins, Michael G, Hruban, Ralph H, Roberts, Nicholas J, Karchin, Rachel, Wood, Laura D

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Optimizing Insertion and Deletion Detection Using Next-Generation Sequencing in the Clinical Laboratory von Craven, Kelly E., Fischer, Catherine G., Jiang, LiQun, Pallavajjala, Aparna, Lin, Ming-Tseh, Eshleman, James R.

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3D genomic mapping reveals multifocality of human pancreatic precancers von Braxton, Alicia M., Kiemen, Ashley L., Grahn, Mia P., Forjaz, André, Parksong, Jeeun, Mahesh Babu, Jaanvi, Lai, Jiaying, Zheng, Lily, Niknafs, Noushin, Jiang, Liping, Cheng, Haixia, Song, Qianqian, Reichel, Rebecca, Graham, Sarah, Damanakis, Alexander I., Fischer, Catherine G., Mou, Stephanie, Metz, Cameron, Granger, Julie, Liu, Xiao-Ding, Bachmann, Niklas, Zhu, Yutong, Liu, YunZhou, Almagro-Pérez, Cristina, Jiang, Ann Chenyu, Yoo, Jeonghyun, Kim, Bridgette, Du, Scott, Foster, Eli, Hsu, Jocelyn Y., Rivera, Paula Andreu, Chu, Linda C., Liu, Fengze, Fishman, Elliot K., Yuille, Alan, Roberts, Nicholas J., Thompson, Elizabeth D., Scharpf, Robert B., Cornish, Toby C., Jiao, Yuchen, Karchin, Rachel, Hruban, Ralph H., Wu, Pei-Hsun, Wirtz, Denis, Wood, Laura D.

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Artificial Intelligence-Assisted Serial Analysis of Clinical Cancer Genomics Data Identifies Changing Treatment Recommendations and Therapeutic Targets von Fischer, Catherine G, Pallavajjala, Aparna, Jiang, LiQun, Anagnostou, Valsamo, Tao, Jessica, Adams, Emily, Eshleman, James R, Gocke, Christopher D, Lin, Ming-Tseh, Platz, Elizabeth A, Xian, Rena R

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Multiregion whole-exome sequencing of intraductal papillary mucinous neoplasms reveals frequent somatic KLF4 mutations predominantly in low-grade regions von Fujikura, Kohei, Hosoda, Waki, Felsenstein, Matthäus, Song, Qianqian, Reiter, Johannes G, Zheng, Lily, Beleva Guthrie, Violeta, Rincon, Natalia, Dal Molin, Marco, Dudley, Jonathan, Cohen, Joshua D, Wang, Pei, Fischer, Catherine G, Braxton, Alicia M, Noë, Michaël, Jongepier, Martine, Fernández-del Castillo, Carlos, Mino-Kenudson, Mari, Schmidt, C Max, Yip-Schneider, Michele T, Lawlor, Rita T, Salvia, Roberto, Roberts, Nicholas J, Thompson, Elizabeth D, Karchin, Rachel, Lennon, Anne Marie, Jiao, Yuchen, Wood, Laura D

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Genomic characterization of malignant progression in neoplastic pancreatic cysts von Noë, Michaël, Niknafs, Noushin, Fischer, Catherine G., Hackeng, Wenzel M., Beleva Guthrie, Violeta, Hosoda, Waki, Debeljak, Marija, Papp, Eniko, Adleff, Vilmos, White, James R., Luchini, Claudio, Pea, Antonio, Scarpa, Aldo, Butturini, Giovanni, Zamboni, Giuseppe, Castelli, Paola, Hong, Seung-Mo, Yachida, Shinichi, Hiraoka, Nobuyoshi, Gill, Anthony J., Samra, Jaswinder S., Offerhaus, G. Johan A., Hoorens, Anne, Verheij, Joanne, Jansen, Casper, Adsay, N. Volkan, Jiang, Wei, Winter, Jordan, Albores-Saavedra, Jorge, Terris, Benoit, Thompson, Elizabeth D., Roberts, Nicholas J., Hruban, Ralph H., Karchin, Rachel, Scharpf, Robert B., Brosens, Lodewijk A. A., Velculescu, Victor E., Wood, Laura D.

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Abstract 237: Coincidence of InDels with missense mutations: 0, 1 or 2 artifacts von Craven, Kelly E., Fischer, Catherine G., Jiang, LiQun, Pallavajjala, Aparna, Lin, Ming-Tseh, Eshleman, James R.

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Multi-region Whole Exome Sequencing of Intraductal Papillary Mucinous Neoplasms Reveals Frequent Somatic KLF4 Mutations Predominantly in Low-Grade Regions von Fujikura, Kohei, Hosoda, Waki, Felsenstein, Matthäus, Song, Qianqian, Reiter, Johannes G., Zheng, Lily, Beleva Guthrie, Violeta, Rincon, Natalia, Dal Molin, Marco, Dudley, Jonathan, Cohen, Joshua D., Wang, Pei, Fischer, Catherine G., Braxton, Alicia M., Noë, Michaël, Jongepier, Martine, Fernández-del Castillo, Carlos, Mino-Kenudson, Mari, Schmidt, C. Max, Yip-Schneider, Michele T., Lawlor, Rita T., Salvia, Roberto, Roberts, Nicholas J., Thompson, Elizabeth D., Karchin, Rachel, Lennon, Anne Marie, Jiao, Yuchen, Wood, Laura D.

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Genomic characterization of malignant progression in neoplastic pancreatic cysts von Noë, Michaël, Niknafs, Noushin, Fischer, Catherine G, Hackeng, Wenzel M, Beleva Guthrie, Violeta, Hosoda, Waki, Debeljak, Marija, Papp, Eniko, Adleff, Vilmos, White, James R, Luchini, Claudio, Pea, Antonio, Scarpa, Aldo, Butturini, Giovanni, Zamboni, Giuseppe, Castelli, Paola, Hong, Seung-Mo, Yachida, Shinichi, Hiraoka, Nobuyoshi, Gill, Anthony J, Samra, Jaswinder S, Offerhaus, G Johan A, Hoorens, Anne, Verheij, Joanne, Jansen, Casper, Adsay, N Volkan, Jiang, Wei, Winter, Jordan, Albores-Saavedra, Jorge, Terris, Benoit, Thompson, Elizabeth D, Roberts, Nicholas J, Hruban, Ralph H, Karchin, Rachel, Scharpf, Robert B, Brosens, Lodewijk A A, Velculescu, Victor E, Wood, Laura D

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Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models von Daniels, Michael J. D., Rivers-Auty, Jack, Schilling, Tom, Spencer, Nicholas G., Watremez, William, Fasolino, Victoria, Booth, Sophie J., White, Claire S., Baldwin, Alex G., Freeman, Sally, Wong, Raymond, Latta, Clare, Yu, Shi, Jackson, Joshua, Fischer, Nicolas, Koziel, Violette, Pillot, Thierry, Bagnall, James, Allan, Stuart M., Paszek, Pawel, Galea, James, Harte, Michael K., Eder, Claudia, Lawrence, Catherine B., Brough, David

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A framework for community and ecosystem genetics: from genes to ecosystems von Whitham, Thomas G., Bailey, Joseph K., Schweitzer, Jennifer A., Shuster, Stephen M., Bangert, Randy K., LeRoy, Carri J., Lonsdorf, Eric V., Allan, Gery J., DiFazio, Stephen P., Potts, Brad M., Fischer, Dylan G., Gehring, Catherine A., Lindroth, Richard L., Marks, Jane C., Hart, Stephen C., Wimp, Gina M., Wooley, Stuart C.

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Community and Ecosystem Genetics: A Consequence of the Extended Phenotype von Whitham, Thomas G., Young, William P., Martinsen, Gregory D., Gehring, Catherine A., Schweitzer, Jennifer A., Shuster, Stephen M., Wimp, Gina M., Fischer, Dylan G., Bailey, Joseph K., Lindroth, Richard L., Woolbright, Scott, Kuske, Cheryl R.

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Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis von Levis, Brooke, Benedetti, Andrea, Thombs, Brett D, Riehm, Kira E, Saadat, Nazanin, Levis, Alexander W, Azar, Marleine, Rice, Danielle B, Chiovitti, Matthew J, Sanchez, Tatiana A, Boruff, Jill, Cuijpers, Pim, Gilbody, Simon, Ioannidis, John P A, Kloda, Lorie A, McMillan, Dean, Patten, Scott B, Shrier, Ian, Ziegelstein, Roy C, Akena, Dickens H, Arroll, Bruce, Ayalon, Liat, Baradaran, Hamid R, Baron, Murray, Bombardier, Charles H, Butterworth, Peter, Carter, Gregory, Chagas, Marcos H, Chan, Juliana C N, Clover, Kerrie, Conwell, Yeates, de Man-van Ginkel, Janneke M, Delgadillo, Jaime, Fann, Jesse R, Fischer, Felix H, Fung, Daniel, Gelaye, Bizu, Goodyear-Smith, Felicity, Greeno, Catherine G, Hall, Brian J, Hambridge, John, Harrison, Patricia A, Härter, Martin, Hegerl, Ulrich, Hides, Leanne, Hobfoll, Stevan E, Hudson, Marie, Inagaki, Masatoshi, Ismail, Khalida, Jetté, Nathalie, Khamseh, Mohammad E, Kiely, Kim M, Kwan, Yunxin, Liu, Shen-Ing, Lotrakul, Manote, Loureiro, Sonia R, Löwe, Bernd, Marsh, Laura, McGuire, Anthony, Mohd Sidik, Sherina, Munhoz, Tiago N, Muramatsu, Kumiko, Osório, Flávia L, Patel, Vikram, Pence, Brian W, Persoons, Philippe, Picardi, Angelo, Reuter, Katrin, Rooney, Alasdair G., Santos, Iná S, Shaaban, Juwita, Sidebottom, Abbey, Simning, Adam, Stafford, Lesley, Sung, Sharon C, Tan, Pei Lin Lynnette, Turner, Alyna, van der Feltz-Cornelis, Christina M, van Weert, Henk C, Vöhringer, Paul A, White, Jennifer, Whooley, Mary A, Winkley, Kirsty, Yamada, Mitsuhiko, Zhang, Yuying

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Circulation of non-polio enteroviruses in 24 EU and EEA countries between 2015 and 2017: a retrospective surveillance study von Bubba, Laura, Broberg, Eeva K, Jasir, Aftab, Simmonds, Peter, Harvala, Heli, Redlberger-Fritz, Monika, Nikolaeva-Glomb, Lubomira, Havlíčková, Martina, Rainetova, Petra, Fischer, Thea K, Midgley, Sofie E., Epštein, Jevgenia, Blomqvist, Soile, Böttcher, Sindy, Keeren, Kathrin, Bujaki, Erika, Farkas, Ágnes, Baldvinsdóttir, Guôrún Erna, Morley, Ursula, De Gascun, Cillian, Pellegrinelli, Laura, Piralla, Antonio, Martinuka, Oksana, Zamjatina, Natālija, Griškevičius, Algirdas, Nguyen, Trung, Dudman, Susanne G., Numanovic, Sanela, Wieczorek, Magdalena, Guiomar, Raquel, Costa, Inês, Cristina, Tecu, Bopegamage, Shubhada, Pastuchova, Katarina, Berginc, Nataša, Cabrerizo, María, González-Sanz, Rubén, Zakikhany, Katherina, Hauzenberger, Elenor, Benschop, Kimberley, Duizer, Erwin, Dunning, Jake, Celma, Cristina, McKenna, James, Feeney, Susan, Templeton, Kate, Moore, Catherine, Cottrell, Simon

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Past, present, and future of global health financing: a review of development assistance, government, out-of-pocket, and other private spending on health for 195 countries, 1995–20... von Chang, Angela Y., Cowling, Krycia, Micah, Angela E., Chen, Catherine S., Ikilezi, Gloria, Tsakalos, Golsum, Wu, Junjie, Zlavog, Bianca S., Ahmed, Anwar E, Alam, Khurshid, Alvis-Guzman, Nelson, Ammar, Walid, Andrei, Catalina Liliana, Arabloo, Jalal, Aremu, Olatunde, Avila-Burgos, Leticia, Ayanore, Martin Amogre, Azari, Samad, Bärnighausen, Till Winfried, Belay, Yared Belete, Berman, Adam E., Busse, Reinhard, Crowe, Christopher Stephen, Cucu, Alexandra, De Neve, Jan-Walter, Deiparine, Selina, Dubey, Manisha, Eskandarieh, Sharareh, Fischer, Florian, Fukumoto, Takeshi, Ghajar, Alireza, Goginashvili, Ketevan, Haakenstad, Annie, Haghparast Bidgoli, Hassan, Harb, Hilda L., Hasanpoor, Edris, Hassen, Hamid Yimam, Henok, Andualem, Heredia-Pi, Ileana, Herteliu, Claudiu, Hoang, Chi Linh, Hole, Michael K., Hosseinzadeh, Mehdi, Hostiuc, Sorin, Ilesanmi, Olayinka Stephen, Irvani, Seyed Sina Naghibi, Jalali, Amir, Jonas, Jost B., Karami Matin, Behzad, Kasaeian, Amir, Kasaye, Habtamu Kebebe, Kazemi Karyani, Ali, Khang, Young-Ho, Kisa, Adnan, Kohler, Stefan, Koyanagi, Ai, Lim, Lee-Ling, Majeed, Azeem, Malekzadeh, Reza, Mehta, Varshil, Milevska Kostova, Neda, Miller, Ted R, Mohajer, Bahram, Mohammad Darwesh, Aso, Mokdad, Ali H, Morrison, Shane Douglas, Mousavi, Seyyed Meysam, Nagarajan, Ahamarshan Jayaraman, Nguyen, Cuong Tat, Nguyen, Son Hoang, Oladimeji, Olanrewaju, Olgiati, Stefano, Olusanya, Jacob Olusegun, Pana, Adrian, Pereira, David M., Piroozi, Bakhtiar, Prada, Sergio I, Rabiee, Mohammad, Rahim, Fakher, Rahimi-Movaghar, Vafa, Roro, Elias Merdassa, Samy, Abdallah M., Sao Jose, Bruno Piassi, Sepanlou, Sadaf G., Sepehrimanesh, Masood, Sisay, Solomon, Torre, Anna, Tovani-Palone, Marcos Roberto, Tran, Khanh Bao, Vargas, Veronica, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vollmer, Sebastian, Yonemoto, Naohiro, Younis, Mustafa Z., Yousefifard, Mahmoud, Zegeye, Elias Asfaw, Ziapour, Arash, Murray, Christopher J L, Dieleman, Joseph L

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Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 von Stark, Benjamin A, Roth, Gregory A, Adebayo, Oladimeji M, Akbarpour, Samaneh, Aljunid, Syed Mohamed, Alvis-Guzman, Nelson, Ansar, Adnan, Antonazzo, Ippazio Cosimo, Ärnlöv, Johan, Artanti, Kurnia Dwi, Athar, Mohammad, Ausloos, Marcel, Baltatu, Ovidiu Constantin, Béjot, Yannick, Bijani, Ali, Bikbov, Boris, Birhanu, Mulugeta M, Brauer, Michael, Butt, Zahid A, Campos-Nonato, Ismael R, Cantu-Brito, Carlos, Carrero, Juan J, Castañeda-Orjuela, Carlos A, Chowdhury, Enayet Karim, D'Amico, Emanuele, Darega Gela, Jiregna, Dhimal, Mandira Lamichhane, Dichgans, Martin, Eftekharzadeh, Sahar, Elgendy, Islam Y, Endres, Matthias, Erku, Daniel Asfaw, Faraon, Emerito Jose A, Feroze, Abdullah Hamid, Gaidhane, Shilpa, Hafezi-Nejad, Nima, Hassan, Treska S, Hayat, Khezar, Huang, Junjie, Ilic, Milena D, Irvani, Seyed Sina Naghibi, Iso, Hiroyasu, Jacob, Louis, Jayawardena, Ranil, Jonas, Jost B, Jozwiak, Jacek Jerzy, Kalkonde, Yogeshwar, Kanchan, Tanuj, Kandel, Himal, Katoto, Patrick DMC, Kayode, Gbenga A, Keshavarz, Pedram, Khan, Maseer, Khubchandani, Jagdish, Kim, Gyu Ri, Kivimäki, Mika, Krishan, Kewal, Krishnamoorthy, Vijay, Lasrado, Savita, Lucchetti, Giancarlo, Lutzky Saute, Ricardo, Magdy Abd El Razek, Hassan, Mahajan, Preetam Bhalchandra, Majeed, Azeem, Malekzadeh, Reza, Martini, Santi, Mehndiratta, Man Mohan, Menezes, Ritesh G, Mersha, Amanual Getnet, Michalek, Irmina Maria, Mohammadian-Hafshejani, Abdollah, Moni, Mohammad Ali, Morze, Jakub, Muruet, Walter, Negoi, Ruxandra Irina, Norrving, Bo, Parekh, Tarang, Polinder, Suzanne, Rezapour, Aziz, Rodriguez, Jefferson Antonio Buendia, Roever, Leonardo, Sha, Feng, Shannawaz, Mohammed, Stortecky, Stefan, Tran, Bach Xuan, Unim, Brigid, Valadan Tahbaz, Sahel, Venketasubramanian, Narayanaswamy, Vo, Bay, Vu, Giang Thu, Vu, Linh Gia, Yadav, Lalit, Yahyazadeh Jabbari, Seyed Hossein, Zaman, Sojib Bin, Zamanian, Maryam, Zhang, Yunquan, Zhang, Zhi-Jiang, Zhong, Chenwen, Zuniga, Yves Miel H, Murray, Christopher J L

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