“Go upstream, young man”: lessons learned from the p38 saga von Hammaker, D, Firestein, G S

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The p38 mitogen-activated protein kinase (MAPK) pathway in rheumatoid arthritis von Schett, G, Zwerina, J, Firestein, G

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Evolving concepts of rheumatoid arthritis von Firestein, Gary S

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The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis von Boyle, D L, Soma, K, Hodge, J, Kavanaugh, A, Mandel, D, Mease, P, Shurmur, R, Singhal, A K, Wei, N, Rosengren, S, Kaplan, I, Krishnaswami, S, Luo, Z, Bradley, J, Firestein, G S

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Choline kinase inhibition in rheumatoid arthritis von Guma, M, Sanchez-Lopez, E, Lodi, A, Garcia-Carbonell, R, Tiziani, S, Karin, M, Lacal, J C, Firestein, G S

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Assessment of rituximab’s immunomodulatory synovial effects (ARISE trial). 1: clinical and synovial biomarker results von Kavanaugh, A, Rosengren, S, Lee, S J, Hammaker, D, Firestein, G S, Kalunian, K, Wei, N, Boyle, D L

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c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis von Han, Z, Boyle, D L, Chang, L, Bennett, B, Karin, M, Yang, L, Manning, A M, Firestein, G S

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Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging p... von Buch, M H, Boyle, D L, Rosengren, S, Saleem, B, Reece, R J, Rhodes, L A, Radjenovic, A, English, A, Tang, H, Vratsanos, G, O’Connor, P, Firestein, G S, Emery, P

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Mitogen activated protein kinase inhibitors: where are we now and where are we going? von Sweeney, S E, Firestein, G S

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Signal transduction networks in rheumatoid arthritis von Hammaker, D, Sweeney, S, Firestein, G S

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Cellular electrophysiological principles that modulate secretion from synovial fibroblasts von Clark, R. B., Schmidt, T. A., Sachse, F. B., Boyle, D., Firestein, G. S., Giles, W. R.

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Starving the synovium: angiogenesis and inflammation in rheumatoid arthritis von Firestein, G S

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MKK3, an upstream activator of p38, contributes to formalin phase 2 and late allodynia in mice von Sorkin, L.S, Boyle, D.L, Hammaker, D, Herman, D.S, Vail, E, Firestein, G.S

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Enhanced gene transfer to arthritic joints using adeno-associated virus type 5: implications for intra-articular gene therapy von Adriaansen, J, Tas, S W, Klarenbeek, P L, Bakker, A C, Apparailly, F, Firestein, G S, Jorgensen, C, Vervoordeldonk, M J B M, Tak, P P

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HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation von Cramer, Thorsten, Yamanishi, Yuji, Clausen, Björn E., Förster, Irmgard, Pawlinski, Rafal, Mackman, Nigel, Haase, Volker H., Jaenisch, Rudolf, Corr, Maripat, Nizet, Victor, Firestein, Gary S., Gerber, Hans-Peter, Ferrara, Napoleone, Johnson, Randall S.

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Validated gene expression biomarker analysis for biopsy‐based clinical trials in ulcerative colitis von Boland, B. S., Boyle, D. L., Sandborn, W. J., Firestein, G. S., Levesque, B. G., Hillman, J., Zhang, B., Proudfoot, J., Eckmann, L., Ernst, P. B., Rivera‐Nieves, J., Pola, S., Copur‐Dahi, N., Chang, J. T.

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NF-kappa B regulation by I kappa B kinase-2 in rheumatoid arthritis synoviocytes von Aupperle, K, Bennett, B, Han, Z, Boyle, D, Manning, A, Firestein, G

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Synergistic benefit in inflammatory arthritis by targeting IκB kinase ϵ and interferon β von Corr, M, Boyle, D L, Ronacher, L, Flores, N, Firestein, G S

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TLR2 Signaling in Chondrocytes Drives Calcium Pyrophosphate Dihydrate and Monosodium Urate Crystal-Induced Nitric Oxide Generation von Liu-Bryan, Ru, Pritzker, Kenneth, Firestein, Gary S, Terkeltaub, Robert

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Expression and Function of Wingless and Frizzled Homologs in Rheumatoid Arthritis von Sen, M, Lauterbach, K, El-Gabalawy, H, Firestein, G S, Corr, M, Carson, D A

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