Pharmacokinetic Benefits of 3,4-Dimethoxy Substitution of a Phenyl Ring and Design of Isosteres Yielding Orally Available Cathepsin K Inhibitors von Crawford, James J, Kenny, Peter W, Bowyer, Jonathan, Cook, Calum R, Finlayson, Jonathan E, Heyes, Christine, Highton, Adrian J, Hudson, Julian A, Jestel, Anja, Krapp, Stephan, Martin, Scott, MacFaul, Philip A, McDermott, Benjamin P, McGuire, Thomas M, Morley, Andrew D, Morris, Jeffrey J, Page, Ken M, Ribeiro, Lyn Rosenbrier, Sawney, Helen, Steinbacher, Stefan, Smith, Caroline, Dossetter, Alexander G

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Isosteric replacements for benzothiazoles and optimisation to potent Cathepsin K inhibitors free from hERG channel inhibition von Dossetter, Alexander G., Bowyer, Jonathan, Cook, Calum R., Crawford, James J., Finlayson, Jonathan E., Heron, Nicola M., Heyes, Christine, Highton, Adrian J., Hudson, Julian A., Jestel, Anja, Krapp, Stephan, MacFaul, Philip A., McGuire, Thomas M., Morley, Andrew D., Morris, Jeffrey J., Page, Ken M., Ribeiro, Lyn Rosenbrier, Sawney, Helen, Steinbacher, Stefan, Smith, Caroline

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(1R,2R)-N-(1-Cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): A Potent and Highly Selective Cathepsin K Inhibitor f... von Dossetter, Alexander G, Beeley, Howard, Bowyer, Jonathan, Cook, Calum R, Crawford, James J, Finlayson, Jonathan E, Heron, Nicola M, Heyes, Christine, Highton, Adrian J, Hudson, Julian A, Jestel, Anja, Kenny, Peter W, Krapp, Stephan, Martin, Scott, MacFaul, Philip A, McGuire, Thomas M, Gutierrez, Pablo Morentin, Morley, Andrew D, Morris, Jeffrey J, Page, Ken M, Ribeiro, Lyn Rosenbrier, Sawney, Helen, Steinbacher, Stefan, Smith, Caroline, Vickers, Madeleine

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4-OXOQUINAZOLIN-3-YL BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CYTOKINE MEDIATED DISEASES von FINLAYSON, JONATHAN E, THOMPSON, CAROLINE R, NASH, IAN A

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Improvements to the Wetland Extent Trends (WET) index as a tool for monitoring natural and human-made wetlands von Darrah, Sarah E., Shennan-Farpón, Yara, Loh, Jonathan, Davidson, Nick C., Finlayson, C. Max, Gardner, Royal C., Walpole, Matt J.

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Delayed versus Immediate Cord Clamping in Preterm Infants von Tarnow-Mordi, William, Morris, Jonathan, Kirby, Adrienne, Robledo, Kristy, Askie, Lisa, Brown, Rebecca, Evans, Nicholas, Finlayson, Sarah, Fogarty, Michael, Gebski, Val, Ghadge, Alpana, Hague, Wendy, Isaacs, David, Jeffery, Michelle, Keech, Anthony, Kluckow, Martin, Popat, Himanshu, Sebastian, Lucille, Aagaard, Kjersti, Belfort, Michael, Pammi, Mohan, Abdel-Latif, Mohamed, Reynolds, Graham, Ariff, Shabina, Sheikh, Lumaan, Chen, Yan, Colditz, Paul, Liley, Helen, Pritchard, Margo, de Luca, Daniele, de Waal, Koert, Forder, Peta, Duley, Lelia, El-Naggar, Walid, Gill, Andrew, Newnham, John, Simmer, Karen, Groom, Katie, Weston, Philip, Gullam, Joanna, Patel, Harshad, Koh, Guan, Lui, Kei, Marlow, Neil, Morris, Scott, Sehgal, Arvind, Wallace, Euan, Soll, Roger, Young, Leslie, Sweet, David, Walker, Susan, Watkins, Andrew, Wright, Ian, Osborn, David, Simes, John

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Willingness to Take, Use of, and Indications for Pre-exposure Prophylaxis Among Men Who Have Sex With Men—20 US Cities, 2014 von Hoots, Brooke E., Finlayson, Teresa, Nerlander, Lina, Paz-Bailey, Gabriela

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Hyperpycnal plume-derived fans in the Santa Barbara Channel, California von Warrick, Jonathan A., Simms, Alexander R., Ritchie, Andy, Steel, Elisabeth, Dartnell, Pete, Conrad, James E., Finlayson, David P.

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HIV-1 DNA predicts disease progression and post-treatment virological control von Williams, James P, Hurst, Jacob, Stöhr, Wolfgang, Robinson, Nicola, Brown, Helen, Fisher, Martin, Kinloch, Sabine, Cooper, David, Schechter, Mauro, Tambussi, Giuseppe, Fidler, Sarah, Carrington, Mary, Babiker, Abdel, Weber, Jonathan, Koelsch, Kersten K, Kelleher, Anthony D, Phillips, Rodney E, Frater, John

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Short-Course Antiretroviral Therapy in Primary HIV Infection von Fidler, Sarah, Porter, Kholoud, Ewings, Fiona, Frater, John, Ramjee, Gita, Cooper, David, Rees, Helen, Fisher, Martin, Schechter, Mauro, Kaleebu, Pontiano, Tambussi, Giuseppe, Kinloch, Sabine, Miro, Jose M, Kelleher, Anthony, McClure, Myra, Kaye, Steve, Gabriel, Michelle, Phillips, Rodney, Weber, Jonathan, Babiker, Abdel

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Synthesis of Indole-Dihydroisoquinoline Sulfonyl Ureas via Three-Component Reactions von Pearson, Stuart E., Fillery, Shaun M., Goldberg, Kristin, Demeritt, Julie E., Eden, Jonathan, Finlayson, Jonathan, Patel, Anil

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The internal structure of poly(methyl methacrylate) latexes in nonpolar solvents von Smith, Gregory N., Finlayson, Samuel D., Gillespie, David A.J., Peach, Jocelyn, Pegg, Jonathan C., Rogers, Sarah E., Shebanova, Olga, Terry, Ann E., Armes, Steven P., Bartlett, Paul, Eastoe, Julian

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Threats to food production and water quality in the Murray–Darling Basin of Australia von Holland, Jonathan E., Luck, Gary W., Max Finlayson, C.

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Postprandial glycaemic dips predict appetite and energy intake in healthy individuals von Wyatt, Patrick, Berry, Sarah E., Finlayson, Graham, O’Driscoll, Ruairi, Hadjigeorgiou, George, Drew, David A., Khatib, Haya Al, Nguyen, Long H., Linenberg, Inbar, Chan, Andrew T., Spector, Tim D., Franks, Paul W., Wolf, Jonathan, Blundell, John, Valdes, Ana M.

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Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors von Wilkinson, Andrew J., Ooi, Nicola, Finlayson, Jonathan, Lee, Victoria E., Lyth, David, Maskew, Kathryn S., Newman, Rebecca, Orr, David, Ansell, Keith, Birchall, Kristian, Canning, Peter, Coombs, Peter, Fusani, Lucia, McIver, Ed, Pisco, João, Ireland, Philip M., Jenkins, Christopher, Norville, Isobel H., Southern, Stephanie J., Cowan, Richard, Hall, Gareth, Kettleborough, Catherine, Savage, Victoria J., Cooper, Ian R.

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Apyrase (Nucleoside Triphosphate-Diphosphohydrolase) and Extracellular Nucleotides Regulate Cotton Fiber Elongation in Cultured Ovules von Clark, Greg, Torres, Jonathan, Finlayson, Scott, Guan, Xueying, Handley, Craig, Lee, Jinsuk, Kays, Julia E, Chen, Z. Jeffery, Roux, Stanley J

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Structured observations reveal slow HIV-1 CTL escape von Roberts, Hannah E, Hurst, Jacob, Robinson, Nicola, Brown, Helen, Flanagan, Peter, Vass, Laura, Fidler, Sarah, Weber, Jonathan, Babiker, Abdel, Phillips, Rodney E, McLean, Angela R, Frater, John

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Assessment of current methane emission quantification techniques for natural gas midstream applications von Liu, Yunsong, Paris, Jean-Daniel, Broquet, Gregoire, Bescós Roy, Violeta, Meixus Fernandez, Tania, Andersen, Rasmus, Russu Berlanga, Andrés, Christensen, Emil, Courtois, Yann, Dominok, Sebastian, Dussenne, Corentin, Eckert, Travis, Finlayson, Andrew, Fernández de la Fuente, Aurora, Gunn, Catlin, Hashmonay, Ram, Grigoleto Hayashi, Juliano, Helmore, Jonathan, Honsel, Soeren, Innocenti, Fabrizio, Irjala, Matti, Log, Torgrim, Lopez, Cristina, Cortés Martínez, Francisco, Martinez, Jonathan, Massardier, Adrien, Nygaard, Helle Gottschalk, Agregan Reboredo, Paula, Rousset, Elodie, Scherello, Axel, Ulbricht, Matthias, Weidmann, Damien, Williams, Oliver, Yarrow, Nigel, Zarea, Murès, Ziegler, Robert, Sciare, Jean, Vrekoussis, Mihalis, Bousquet, Philippe

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Plasma HIV viral rebound following protocol-indicated cessation of ART commenced in primary and chronic HIV infection von Hamlyn, Elizabeth, Ewings, Fiona M, Porter, Kholoud, Cooper, David A, Tambussi, Giuseppe, Schechter, Mauro, Pedersen, Court, Okulicz, Jason F, McClure, Myra, Babiker, Abdel, Weber, Jonathan, Fidler, Sarah

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The effect of short-course antiretroviral therapy initiated in primary HIV-1 infection on interleukin-6 and D-dimer levels von Hamlyn, Elizabeth, Stöhr, Wolfgang, Cooper, David A, Fisher, Martin, Tambussi, Giuseppe, Schechter, Mauro, Miro, Jose M, Vanobberghen, Fiona, Babiker, Abdel, Weber, Jonathan, Mcclure, Myra, Porter, Kholoud, Fidler, Sarah

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