Total Syntheses of Epothilones A and B via a Macrolactonization-Based Strategy von Nicolaou, K. C, Ninkovic, S, Sarabia, F, Vourloumis, D, He, Y, Vallberg, H, Finlay, M. R. V, Yang, Z

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Chemistry, biology and medicine of selected tubulin polymerizing agents von Nicolaou, K. C., Hepworth, David, King, N. P., Finlay, M. R. V.

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Total synthesis of Epothilone E and related side-chain modified analogues via a stille coupling based strategy von Nicolaou, K.C., King, N.P., Finlay, M.R.V., He, Y., Roschangar, F., Vourloumis, D., Vallberg, H., Sarabia, F., Ninkovic, S., Hepworth, D.

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Defining a Healthy Human Gut Microbiome: Current Concepts, Future Directions, and Clinical Applications von Bäckhed, Fredrik, Fraser, Claire M., Ringel, Yehuda, Sanders, Mary Ellen, Sartor, R. Balfour, Sherman, Philip M., Versalovic, James, Young, Vincent, Finlay, B. Brett

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Preclinical Comparison of the Blood-brain barrier Permeability of Osimertinib with Other EGFR TKIs von Colclough, Nicola, Chen, Kan, Johnström, Peter, Strittmatter, Nicole, Yan, Yumei, Wrigley, Gail L, Schou, Magnus, Goodwin, Richard, Varnäs, Katarina, Adua, Sally J, Zhao, Minghui, Nguyen, Don X, Maglennon, Gareth, Barton, Peter, Atkinson, James, Zhang, Lin, Janefeldt, Annika, Wilson, Joanne, Smith, Aaron, Takano, Akihiro, Arakawa, Ryosuke, Kondrashov, Mikhail, Malmquist, Jonas, Revunov, Evgeny, Vazquez-Romero, Ana, Moein, Mohammad Mahdi, Windhorst, Albert D, Karp, Natasha A, Finlay, M Raymond V, Ward, Richard A, Yates, James W T, Smith, Paul D, Farde, Lars, Cheng, Zack, Cross, Darren A E

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Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy von Willoughby, Catherine E, Jiang, Yanyan, Thomas, Huw D, Willmore, Elaine, Kyle, Suzanne, Wittner, Anita, Phillips, Nicole, Zhao, Yan, Tudhope, Susan J, Prendergast, Lisa, Junge, Gesa, Lourenco, Luiza Madia, Finlay, M Raymond V, Turner, Paul, Munck, Joanne M, Griffin, Roger J, Rennison, Tommy, Pickles, James, Cano, Celine, Newell, David R, Reeves, Helen L, Ryan, Anderson J, Wedge, Stephen R

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Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions von Floc'h, Nicolas, Martin, Matthew J, Riess, Jonathan W, Orme, Jonathan P, Staniszewska, Anna D, Ménard, Ludovic, Cuomo, Maria Emanuela, O'Neill, Daniel J, Ward, Richard A, Finlay, M Raymond V, McKerrecher, Darren, Cheng, Mingshan, Vang, Daniel P, Burich, Rebekah A, Keck, James G, Gandara, David R, Mack, Philip C, Cross, Darren A E

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The Discovery of 7‑Methyl-2-[(7-methyl[1,2,4]triazolo[1,5‑a]pyridin-6-yl)amino]-9-(tetrahydro‑2H‑pyran-4-yl)-7,9-dihydro‑8H‑purin-8-one (AZD7648), a Potent and Selective DNA-Depend... von Goldberg, Frederick W, Finlay, M. Raymond V, Ting, Attilla K. T, Beattie, David, Lamont, Gillian M, Fallan, Charlene, Wrigley, Gail L, Schimpl, Marianne, Howard, Martin R, Williamson, Beth, Vazquez-Chantada, Mercedes, Barratt, Derek G, Davies, Barry R, Cadogan, Elaine B, Ramos-Montoya, Antonio, Dean, Emma

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AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity von Fok, Jacqueline H. L., Ramos-Montoya, Antonio, Vazquez-Chantada, Mercedes, Wijnhoven, Paul W. G., Follia, Valeria, James, Neil, Farrington, Paul M., Karmokar, Ankur, Willis, Sophie E., Cairns, Jonathan, Nikkilä, Jenni, Beattie, David, Lamont, Gillian M., Finlay, M. Raymond V., Wilson, Joanne, Smith, Aaron, O’Connor, Lenka Oplustil, Ling, Stephanie, Fawell, Stephen E., O’Connor, Mark J., Hollingsworth, Simon J., Dean, Emma, Goldberg, Frederick W., Davies, Barry R., Cadogan, Elaine B.

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ChemInform Abstract: Total Synthesis of 26-Hydroxy-epothilone B and Related Analogues via a Macrolactonization Based Strategy von NICOLAOU, K. C., FINLAY, M. R. V., NINKOVIC, S., SARABIA, F.

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Lymphangioleiomyomatosis Diagnosis and Management: High-Resolution Chest Computed Tomography, Transbronchial Lung Biopsy, and Pleural Disease Management. An Official American Thora... von Gupta, Nishant, Finlay, Geraldine A, Kotloff, Robert M, Strange, Charlie, Wilson, Kevin C, Young, Lisa R, Taveira-DaSilva, Angelo M, Johnson, Simon R, Cottin, Vincent, Sahn, Steven A, Ryu, Jay H, Seyama, Kuniaki, Inoue, Yoshikazu, Downey, Gregory P, Han, MeiLan K, Colby, Thomas V, Wikenheiser-Brokamp, Kathryn A, Meyer, Cristopher A, Smith, Karen, Moss, Joel, McCormack, Francis X

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European Evidence-based (S3) Guidelines for the Treatment of Acne von Nast, A., Dréno, B., Bettoli, V., Degitz, K., Erdmann, R., Finlay, A. Y., Ganceviciene, R., Haedersdal, M., Layton, A., López-Estebaranz, J.L., Ochsendorf, F., Oprica, C., Rosumeck, S., Rzany, B., Sammain, A., Simonart, T., Veien, N.K., Živković, M.V., Zouboulis, C.C., Gollnick, H.

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ChemInform Abstract: Total Synthesis of 26-Hydroxyepothilone B and Related Analogues von NICOLAOU, K. C., NINKOVIC, S., FINLAY, M. R. V., SARABIA, F., LI, T.

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ChemInform Abstract: Probing the Ring Size of Epothilones: Total Synthesis of [14]-, [15]-, [17]-, and [18]Epothilones A von NICOLAOU, K. C., SARABIA, F., NINKOVIC, S., FINLAY, M. R. V., BODDY, C. N. C.

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ChemInform Abstract: Studies Towards the Synthesis of the Zaragozic Acids: A Novel Epoxide Cyclization Approach to the Formation of the Bicyclic Acetal Core von PATERSON, I., FESSNER, K., FINLAY, M. R. V., JACOBS, M. F.

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ChemInform Abstract: Total Synthesis of Oxazole- and Cyclopropane-Containing Epothilone B Analogues by the Macrolactonization Approach von NICOLAOU, K. C., SARABIA, F., FINLAY, M. R. V., NINKOVIC, S., KING, N. P., VOURLOUMIS, D., HE, Y.

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AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer von Cross, Darren A E, Ashton, Susan E, Ghiorghiu, Serban, Eberlein, Cath, Nebhan, Caroline A, Spitzler, Paula J, Orme, Jonathon P, Finlay, M Raymond V, Ward, Richard A, Mellor, Martine J, Hughes, Gareth, Rahi, Amar, Jacobs, Vivien N, Red Brewer, Monica, Ichihara, Eiki, Sun, Jing, Jin, Hailing, Ballard, Peter, Al-Kadhimi, Katherine, Rowlinson, Rachel, Klinowska, Teresa, Richmond, Graham H P, Cantarini, Mireille, Kim, Dong-Wan, Ranson, Malcolm R, Pao, William

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Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor von Finlay, M. Raymond V, Anderton, Mark, Ashton, Susan, Ballard, Peter, Bethel, Paul A, Box, Matthew R, Bradbury, Robert H, Brown, Simon J, Butterworth, Sam, Campbell, Andrew, Chorley, Christopher, Colclough, Nicola, Cross, Darren A. E, Currie, Gordon S, Grist, Matthew, Hassall, Lorraine, Hill, George B, James, Daniel, James, Michael, Kemmitt, Paul, Klinowska, Teresa, Lamont, Gillian, Lamont, Scott G, Martin, Nathaniel, McFarland, Heather L, Mellor, Martine J, Orme, Jonathon P, Perkins, David, Perkins, Paula, Richmond, Graham, Smith, Peter, Ward, Richard A, Waring, Michael J, Whittaker, David, Wells, Stuart, Wrigley, Gail L

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Dawning of the N=32 Shell Closure Seen through Precision Mass Measurements of Neutron-Rich Titanium Isotopes von Leistenschneider, E, Reiter, M P, Ayet San Andrés, S, Kootte, B, Holt, J D, Navrátil, P, Babcock, C, Barbieri, C, Barquest, B R, Bergmann, J, Bollig, J, Brunner, T, Dunling, E, Finlay, A, Geissel, H, Graham, L, Greiner, F, Hergert, H, Hornung, C, Jesch, C, Klawitter, R, Lan, Y, Lascar, D, Leach, K G, Lippert, W, McKay, J E, Paul, S F, Schwenk, A, Short, D, Simonis, J, Somà, V, Steinbrügge, R, Stroberg, S R, Thompson, R, Wieser, M E, Will, C, Yavor, M, Andreoiu, C, Dickel, T, Dillmann, I, Gwinner, G, Plaß, W R, Scheidenberger, C, Kwiatkowski, A A, Dilling, J

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Evaluation of candidate models for the 13th generation International Geomagnetic Reference Field von Alken, P., Thébault, E., Beggan, C. D., Aubert, J., Baerenzung, J., Brown, W. J., Califf, S., Chulliat, A., Cox, G. A., Finlay, C. C., Fournier, A., Gillet, N., Hammer, M. D., Holschneider, M., Hulot, G., Korte, M., Lesur, V., Livermore, P. W., Lowes, F. J., Macmillan, S., Nair, M., Olsen, N., Ropp, G., Rother, M., Schnepf, N. R., Stolle, C., Toh, H., Vervelidou, F., Vigneron, P., Wardinski, I.

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