Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq von Venteicher, Andrew S., Tirosh, Itay, Hebert, Christine, Yizhak, Keren, Neftel, Cyril, Filbin, Mariella G., Hovestadt, Volker, Escalante, Leah E., Shaw, McKenzie L., Rodman, Christopher, Gillespie, Shawn M., Dionne, Danielle, Luo, Christina C., Ravichandran, Hiranmayi, Mylvaganam, Ravindra, Mount, Christopher, Onozato, Maristela L., Nahed, Brian V., Wakimoto, Hiroaki, Curry, William T., Iafrate, A. John, Rivera, Miguel N., Frosch, Matthew P., Golub, Todd R., Brastianos, Priscilla K., Getz, Gad, Patel, Anoop P., Monje, Michelle, Cahill, Daniel P., Rozenblatt-Rosen, Orit, Louis, David N., Bernstein, Bradley E., Regev, Aviv, Suvà, Mario L.

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Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma von Lin, Grant L, Nagaraja, Surya, Filbin, Mariella G, Suvà, Mario L, Vogel, Hannes, Monje, Michelle

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Why haven't we solved intracranial pediatric ependymoma? Current questions and barriers to treatment advances von Hwang, Eugene I., Hanson, Derek, Filbin, Mariella G., Mack, Stephen C.

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Bromodomain and Extra-Terminal Protein Inhibitors: Biologic Insights and Therapeutic Potential in Pediatric Brain Tumors von Groves, Andrew, Clymer, Jessica, Filbin, Mariella G.

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Molecular and clinicopathologic features of gliomas harboring NTRK fusions von Torre, Matthew, Vasudevaraja, Varshini, Serrano, Jonathan, DeLorenzo, Michael, Malinowski, Seth, Blandin, Anne-Florence, Pages, Melanie, Ligon, Azra H., Dong, Fei, Meredith, David M., Nasrallah, MacLean P., Horbinski, Craig, Dahiya, Sonika, Ligon, Keith L., Santi, Mariarita, Ramkissoon, Shakti H., Filbin, Mariella G., Snuderl, Matija, Alexandrescu, Sanda

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Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells von Reitman, Zachary J., Paolella, Brenton R., Bergthold, Guillaume, Pelton, Kristine, Becker, Sarah, Jones, Robert, Sinai, Claire E., Malkin, Hayley, Huang, Ying, Grimmet, Leslie, Herbert, Zachary T., Sun, Yu, Weatherbee, Jessica L., Alberta, John A., Daley, John F., Rozenblatt-Rosen, Orit, Condurat, Alexandra L., Qian, Kenin, Khadka, Prasidda, Segal, Rosalind A., Haas-Kogan, Daphne, Filbin, Mariella G., Suva, Mario L., Regev, Aviv, Stiles, Charles D., Kieran, Mark W., Goumnerova, Liliana, Ligon, Keith L., Shalek, Alex K., Bandopadhayay, Pratiti, Beroukhim, Rameen

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Immunotherapy approaches for the treatment of diffuse midline gliomas von Bernstock, Joshua D., Hoffman, Samantha E., Kappel, Ari D., Valdes, Pablo A., Essayed, Walid Ibn, Klinger, Neil V., Kang, Kyung-Don, Totsch, Stacie K., Olsen, Hannah E., Schlappi, Charles W., Filipski, Katharina, Gessler, Florian A., Baird, Lissa, Filbin, Mariella G., Hashizume, Rintaro, Becher, Oren J., Friedman, Gregory K.

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Of Brains and Blood: Developmental Origins of Glioma Diversity? von Filbin, Mariella G., Stiles, Charles D.

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Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways von Pun, Matthew, Pratt, Drew, Nano, Patricia R, Joshi, Piyush K, Jiang, Li, Englinger, Bernhard, Rao, Arvind, Cieslik, Marcin, Chinnaiyan, Arul M, Aldape, Kenneth, Pfister, Stefan, Filbin, Mariella G, Bhaduri, Aparna, Venneti, Sriram

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An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma von Neftel, Cyril, Laffy, Julie, Filbin, Mariella G., Hara, Toshiro, Shore, Marni E., Rahme, Gilbert J., Richman, Alyssa R., Silverbush, Dana, Shaw, McKenzie L., Hebert, Christine M., Dewitt, John, Gritsch, Simon, Perez, Elizabeth M., Gonzalez Castro, L. Nicolas, Lan, Xiaoyang, Druck, Nicholas, Rodman, Christopher, Dionne, Danielle, Kaplan, Alexander, Bertalan, Mia S., Small, Julia, Pelton, Kristine, Becker, Sarah, Bonal, Dennis, Nguyen, Quang-De, Servis, Rachel L., Fung, Jeremy M., Mylvaganam, Ravindra, Mayr, Lisa, Gojo, Johannes, Haberler, Christine, Geyeregger, Rene, Czech, Thomas, Slavc, Irene, Nahed, Brian V., Curry, William T., Carter, Bob S., Wakimoto, Hiroaki, Brastianos, Priscilla K., Batchelor, Tracy T., Stemmer-Rachamimov, Anat, Martinez-Lage, Maria, Frosch, Matthew P., Stamenkovic, Ivan, Riggi, Nicolo, Rheinbay, Esther, Monje, Michelle, Rozenblatt-Rosen, Orit, Cahill, Daniel P., Patel, Anoop P., Hunter, Tony, Verma, Inder M., Ligon, Keith L., Louis, David N., Regev, Aviv, Bernstein, Bradley E., Tirosh, Itay, Suvà, Mario L.

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GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas von Majzner, Robbie G., Ramakrishna, Sneha, Yeom, Kristen W., Patel, Shabnum, Chinnasamy, Harshini, Schultz, Liora M., Richards, Rebecca M., Jiang, Li, Barsan, Valentin, Mancusi, Rebecca, Geraghty, Anna C., Good, Zinaida, Mochizuki, Aaron Y., Gillespie, Shawn M., Toland, Angus Martin Shaw, Mahdi, Jasia, Reschke, Agnes, Nie, Esther H., Chau, Isabelle J., Rotiroti, Maria Caterina, Mount, Christopher W., Baggott, Christina, Mavroukakis, Sharon, Egeler, Emily, Moon, Jennifer, Erickson, Courtney, Green, Sean, Kunicki, Michael, Fujimoto, Michelle, Ehlinger, Zach, Reynolds, Warren, Kurra, Sreevidya, Warren, Katherine E., Prabhu, Snehit, Vogel, Hannes, Rasmussen, Lindsey, Cornell, Timothy T., Partap, Sonia, Fisher, Paul G., Campen, Cynthia J., Filbin, Mariella G., Grant, Gerald, Sahaf, Bita, Davis, Kara L., Feldman, Steven A., Mackall, Crystal L., Monje, Michelle

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VRK1 as a synthetic lethal target in VRK2 promoter-methylated cancers of the nervous system von So, Jonathan, Mabe, Nathaniel W, Englinger, Bernhard, Chow, Kin-Hoe, Moyer, Sydney M, Yerrum, Smitha, Trissal, Maria C, Marques, Joana G, Kwon, Jason J, Shim, Brian, Pal, Sangita, Panditharatna, Eshini, Quinn, Thomas, Schaefer, Daniel A, Jeong, Daeun, Mayhew, David L, Hwang, Justin, Beroukhim, Rameen, Ligon, Keith L, Stegmaier, Kimberly, Filbin, Mariella G, Hahn, William C

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Stalled developmental programs at the root of pediatric brain tumors von Jessa, Selin, Blanchet-Cohen, Alexis, Krug, Brian, Vladoiu, Maria, Coutelier, Marie, Faury, Damien, Poreau, Brice, De Jay, Nicolas, Hébert, Steven, Monlong, Jean, Farmer, W. Todd, Donovan, Laura K., Hu, Yixing, McConechy, Melissa K., Cavalli, Florence M. G., Mikael, Leonie G., Ellezam, Benjamin, Richer, Maxime, Allaire, Andréa, Weil, Alexander G., Atkinson, Jeffrey, Farmer, Jean-Pierre, Dudley, Roy W. R., Larouche, Valerie, Crevier, Louis, Albrecht, Steffen, Filbin, Mariella G., Sartelet, Hervé, Lutz, Pierre-Eric, Nagy, Corina, Turecki, Gustavo, Costantino, Santiago, Dirks, Peter B., Murai, Keith K., Bourque, Guillaume, Ragoussis, Jiannis, Garzia, Livia, Taylor, Michael D., Jabado, Nada, Kleinman, Claudia L.

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Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State von Nagaraja, Surya, Quezada, Michael A., Gillespie, Shawn M., Arzt, Marlene, Lennon, James J., Woo, Pamelyn J., Hovestadt, Volker, Kambhampati, Madhuri, Filbin, Mariella G., Suva, Mario L., Nazarian, Javad, Monje, Michelle

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The imitation game: How glioblastoma outmaneuvers immune attack von Liu, Ilon, Hack, Olivia A., Filbin, Mariella G.

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Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma von Tirosh, Itay, Venteicher, Andrew S., Hebert, Christine, Escalante, Leah E., Patel, Anoop P., Yizhak, Keren, Fisher, Jonathan M., Rodman, Christopher, Mount, Christopher, Filbin, Mariella G., Neftel, Cyril, Desai, Niyati, Nyman, Jackson, Izar, Benjamin, Luo, Christina C., Francis, Joshua M., Patel, Aanand A., Onozato, Maristela L., Riggi, Nicolo, Livak, Kenneth J., Gennert, Dave, Satija, Rahul, Nahed, Brian V., Curry, William T., Martuza, Robert L., Mylvaganam, Ravindra, Iafrate, A. John, Frosch, Matthew P., Golub, Todd R., Rivera, Miguel N., Getz, Gad, Rozenblatt-Rosen, Orit, Cahill, Daniel P., Monje, Michelle, Bernstein, Bradley E., Louis, David N., Regev, Aviv, Suvà, Mario L.

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Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG von Anastas, Jamie N., Zee, Barry M., Kalin, Jay H., Kim, Mirhee, Guo, Robyn, Alexandrescu, Sanda, Blanco, Mario Andres, Giera, Stefanie, Gillespie, Shawn M., Das, Jayanta, Wu, Muzhou, Nocco, Sarah, Bonal, Dennis M., Nguyen, Quang-De, Suva, Mario L., Bernstein, Bradley E., Alani, Rhoda, Golub, Todd R., Cole, Philip A., Filbin, Mariella G., Shi, Yang

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Resolving medulloblastoma cellular architecture by single-cell genomics von Hovestadt, Volker, Smith, Kyle S., Bihannic, Laure, Filbin, Mariella G., Shaw, McKenzie L., Baumgartner, Alicia, DeWitt, John C., Groves, Andrew, Mayr, Lisa, Weisman, Hannah R., Richman, Alyssa R., Shore, Marni E., Goumnerova, Liliana, Rosencrance, Celeste, Carter, Robert A., Phoenix, Timothy N., Hadley, Jennifer L., Tong, Yiai, Houston, Jim, Ashmun, Richard A., DeCuypere, Michael, Sharma, Tanvi, Flasch, Diane, Silkov, Antonina, Ligon, Keith L., Pomeroy, Scott L., Rivera, Miguel N., Rozenblatt-Rosen, Orit, Rusert, Jessica M., Wechsler-Reya, Robert J., Li, Xiao-Nan, Peyrl, Andreas, Gojo, Johannes, Kirchhofer, Dominik, Lötsch, Daniela, Czech, Thomas, Dorfer, Christian, Haberler, Christine, Geyeregger, Rene, Halfmann, Angela, Gawad, Charles, Easton, John, Pfister, Stefan M., Regev, Aviv, Gajjar, Amar, Orr, Brent A., Slavc, Irene, Robinson, Giles W., Bernstein, Bradley E., Suvà, Mario L., Northcott, Paul A.

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Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis von Chen, Carol C.L., Deshmukh, Shriya, Jessa, Selin, Hadjadj, Djihad, Lisi, Véronique, Andrade, Augusto Faria, Faury, Damien, Jawhar, Wajih, Dali, Rola, Suzuki, Hiromichi, Pathania, Manav, A, Deli, Dubois, Frank, Woodward, Eleanor, Hébert, Steven, Coutelier, Marie, Karamchandani, Jason, Albrecht, Steffen, Brandner, Sebastian, De Jay, Nicolas, Gayden, Tenzin, Bajic, Andrea, Harutyunyan, Ashot S., Marchione, Dylan M., Mikael, Leonie G., Juretic, Nikoleta, Zeinieh, Michele, Russo, Caterina, Maestro, Nicola, Bassenden, Angelia V., Hauser, Peter, Virga, József, Bognar, Laszlo, Klekner, Almos, Zapotocky, Michal, Vicha, Ales, Krskova, Lenka, Vanova, Katerina, Zamecnik, Josef, Sumerauer, David, Ekert, Paul G., Ziegler, David S., Ellezam, Benjamin, Filbin, Mariella G., Blanchette, Mathieu, Hansford, Jordan R., Khuong-Quang, Dong-Anh, Berghuis, Albert M., Weil, Alexander G., Garcia, Benjamin A., Garzia, Livia, Mack, Stephen C., Beroukhim, Rameen, Ligon, Keith L., Taylor, Michael D., Bandopadhayay, Pratiti, Kramm, Christoph, Pfister, Stefan M., Korshunov, Andrey, Sturm, Dominik, Jones, David T.W., Salomoni, Paolo, Kleinman, Claudia L., Jabado, Nada

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Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas von Harpaz, Nofar, Mittelman, Tamir, Beresh, Olga, Griess, Ofir, Furth, Noa, Salame, Tomer-Meir, Oren, Roni, Fellus-Alyagor, Liat, Harmelin, Alon, Alexandrescu, Sanda, Marques, Joana Graca, Filbin, Mariella G., Ron, Guy, Shema, Efrat

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