Radiation-Induced Energy Migration within Solid DNA: The Role of Misonidazole as an Electron Trap von Al-Kazwini, Akeel T., O'Neill, Peter, Adams, Gerald E., Fielden, E. Martin

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Radiation-Induced Luminescence in DNA: Evidence for Long-Range Electron Migration von Al-Kazwini, Akeel T., Adams, Gerald E., O'Neill, Peter, Naylor, Matthew A., Fielden, E. Martin

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The effects of pH and various salts upon the activity of a series of superoxide dismutases von O'Neill, P, Davies, S, Fielden, E M, Calabrese, L, Capo, C, Marmocchi, F, Natoli, G, Rotilio, G

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Dual-Function 2-Nitroimidazoles as Hypoxic Cell Radiosensitizers and Bioreductive Cytotoxins: In Vivo Evaluation in KHT Murine Sarcomas von Cole, Shirley, Stratford, Ian J., Adams, Gerald E., Fielden, E. Martin, Jenkins, Terence C.

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Dual function nitroimidazoles less toxic than RSU 1069: selection of candidate drugs for clinical trial (RB 6145 and/or PD 130908) von Cole, S., Stratford, I.J., Fielden, E.M., Adams, G.E., Leopold, W., Elliott, W., Suto, M., Sebolt-Leopold, J.

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Radiolytic and photochemical reduction of the hypoxic cytotoxin 1,2-dihydro-8-(4-methylpiperazinyl)-4-phenylimidazo [1,2- a] pyrido [3,2- e] pyrazine 5-oxide (RB90740) and a potent... von Naylor, Matthew A., Sutton, Bridget M., Nolan, John, O'Neill, Peter, Martin Fielden, E., Adams, Gerald E., Stratford, Ian J.

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Assessment of a range of novel nitro-aromatic radiosensitizers and bioreductive drugs von Fielden, E.M., Adams, G.E., Cole, S., Naylor, M.A., O'Neill, P., Stephens, M.A., Stratford, I.T.

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2-Nitroimidazole dual-function bioreductive drugs: studies on the effects of regioisomerism and side-chain structural modifications on differential cytotoxicity and radiosensitizat... von Naylor, Matthew A, Threadgill, Michael D, Webb, Paul, Stratford, Ian J, Stephens, Miriam A, Fielden, E. Martin, Adams, Gerald E

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Synthesis and evaluation of novel electrophilic nitrofuran carboxamides and carboxylates as radiosensitizers and bioreductively activated cytotoxins von Naylor, Matthew A, Stephens, Miriam A, Cole, Shirley, Threadgill, Michael D, Stratford, Ian J, O'Neill, Peter, Fielden, E. Martin, Adams, Gerald E

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Mechanism of action of superoxide dismutase from pulse radiolysis and electron paramagnetic resonance. Evidence that only half the active sites function in catalysis von Fielden, E M, Roberts, P B, Bray, R C, Lowe, D J, Mautner, G N, Rotilio, G, Calabrese, L

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Pharmacokinetics, metabolism and distribution of 1,2-dihydro-8-(4-methylpiperazinyl)-4-phenylimidazo [1,2-A] pyrido [3,2-E] pyrazine-5-oxide in C3H mice von SUTTON, B. M, REEVES, N. J, NAYLOR, M. A, FIELDEN, E. M, COLE, S, ADAMS, G. E, STRATFORD, I. J

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Synthesis of a series of nitrothiophenes with basic or electrophilic substituents and evaluation as radiosensitizers and as bioreductively activated cytotoxins von Threadgill, Michael D, Webb, Paul, O'Neill, Peter, Naylor, Matthew A, Stephens, Miriam A, Stratford, Ian J, Cole, Shirley, Adams, Gerald E, Fielden, E. Martin

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An Effect of Elevated Postirradiation pH on the Yield of Double-Strand Breaks in DNA from Irradiated Bacterial Cells von Tilby, Michael J., Loverock, Pamela S., Fielden, E. Martin

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A pulse-radiolysis study of the manganese-containing superoxide dismutase from Bacillus stearothermophilus. A kinetic model for the enzyme action von McAdam, M E, Fox, R A, Lavelle, F, Fielden, E M

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Nitroheterocyclic compounds as radiation sensitizers and bioreductive drugs von Adams, G.E., Stratford, I.J., Bremner, J.C.M., Cole, S., Edwards, H.S., Fielden, E.M.

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Enhancement of DNA damage in mammalian cells upon bioreduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131 von Jenner, Terry J., Sapora, Orazio, O'Neill, Peter, Martin Fielden, E.

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A pulse-radiolysis study of the catalytic mechanism of the iron-containing superoxide dismutase from Photobacterium leiognathi von Lavelle, F, McAdam, M E, Fielden, E M, Roberts, P B

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A comparison of the techniques of alkaline filter elution and alkaline sucrose sedimentation used to assess DNA damage induced by 2-nitroimidazoles von Crump, Paul W., Fielden, E.Martin, Jenner, Terry J., O'neill, Peter

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The repair of DNA damage induced in V79 mammalian cells by the nitroimidazole-aziridine, RSU-1069: Implications for radiosensitization von Jenner, Terry J., O'neill, Peter, Crump, Paul W., Fielden, E.Martin, Sapora, Orazio, Santodonato, Laura

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Synthesis and evaluation of .alpha.-[[(2-haloethyl)amino]methyl]-2-nitro-1H-imidazole-1-ethanols as prodrugs of .alpha.-[(1-aziridinyl)methyl]-2-nitro-1H-imidazole-1-ethanol (RSU-1... von Jenkins, Terence C, Naylor, Matthew A, O'Neill, Peter, Threadgill, Michael D, Cole, Shirley, Stratford, Ian J, Adams, Gerald E, Fielden, E. Martin, Suto, Mark J, Stier, Michael A

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