Antiviral prodrugs – the development of successful prodrug strategies for antiviral chemotherapy von De Clercq, Erik, Field, Hugh J

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Recent developments in anti-herpesvirus drugs von Field, Hugh J, Vere Hodge, R Anthony

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Antiviral drug resistance and helicase–primase inhibitors of herpes simplex virus von Field, Hugh J, Biswas, Subhajit

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AVCC 1990–2015 – A journal to combine antiviral biology and antiviral chemistry enters the third era von Field, Hugh J

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Baseline sensitivity of HSV-1 and HSV-2 clinical isolates and defined acyclovir-resistant strains to the helicase–primase inhibitor pritelivir von Field, Hugh J., Huang, Meei-Li, Lay, Elizabeth M., Mickleburgh, Ian, Zimmermann, Holger, Birkmann, Alexander

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Detection of HSV-1 variants highly resistant to the helicase–primase inhibitor BAY 57-1293 at high frequency in 2 of 10 recent clinical isolates of HSV-1 von Biswas, Subhajit, Smith, Christopher, Field, Hugh J.

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Pharmacokinetics-Pharmacodynamics of the Helicase-Primase Inhibitor Pritelivir following Treatment of Wild-Type or Pritelivir-Resistant Virus Infection in a Murine Herpes Simplex V... von BISWAS, Subhajit, SUKLA, Soumi, GOLDNER, Thomas, FIELD, Hugh J, KROPEIT, Dirk, PAULSEN, Daniela, WELBERS, André, RUEBSAMEN-SCHAEFF, Helga, ZIMMERMANN, Holger, BIRKMANN, Alexander

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A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predict... von Biswas, Subhajit, Miguel, Ricardo Nunez, Sukla, Soumi, Field, Hugh J

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Mismatch primer-based PCR reveals that helicase–primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubat... von Sukla, Soumi, Biswas, Subhajit, Birkmann, Alexander, Lischka, Peter, Zimmermann, Holger, Field, Hugh J.

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The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1 von Biswas, Subhajit, Jennens, Lyn, Field, Hugh J.

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Herpes Simplex Virus Helicase—Primase Inhibitors: Recent Findings from the Study of Drug Resistance Mutations von Biswas, Subhajit, Field, Hugh J

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Effects of therapy using a helicase–primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant von Sukla, Soumi, Biswas, Subhajit, Birkmann, Alexander, Lischka, Peter, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Field, Hugh J.

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The effect of passive immunization on the acute phase of infection in a murine model of EHV‐1 von Awan, Aftab, Tulp, Orien, Field, Hugh

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Antiviral Chemistry & Chemotherapy's Current Antiviral Agents FactFile (2nd Edition) von Field, Hugh J

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A single drug-resistance mutation in HSV-1 UL52 primase points to a difference between two helicase–primase inhibitors in their mode of interaction with the antiviral target von Biswas, Subhajit, Kleymann, Gerald, Swift, Mihaiela, Tiley, Laurence S., Lyall, Jonathan, Aguirre-Hernández, Jesús, Field, Hugh J.

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High frequency of spontaneous helicase-primase inhibitor (BAY 57-1293) drug-resistant variants in certain laboratory isolates of HSV-1 von BISWAS, Subhajit, SWIFT, Mihaiela, FIELD, Hugh J

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Development of a quantitative real-time TaqMan PCR assay for testing the susceptibility of feline herpesvirus-1 to antiviral compounds von Hussein, Islam T.M., Field, Hugh J.

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Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase–primase inhibitors, variously affect virus growth rate and pathogenicity von Biswas, Subhajit, Tiley, Laurence S., Zimmermann, Holger, Birkmann, Alexander, Field, Hugh J.

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Penciclovir is a potent inhibitor of feline herpesvirus-1 with susceptibility determined at the level of virus-encoded thymidine kinase von Hussein, Islam T.M., Menashy, Rebecca V., Field, Hugh J.

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Immunopathology in Lungs after Intranasal Challenge with Live Virus in an EHV‐1 Murine Model: Lessons Learned from Unexpected Findings von Awan, Aftab, Tulp, Orien Lee, Einstein, George P., Field, Hugh

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