Uncovering the role of 5-hydroxymethylcytosine in the epigenome von Branco, Miguel R., Ficz, Gabriella, Reik, Wolf

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Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution von Booth, Michael J., Branco, Miguel R., Ficz, Gabriella, Oxley, David, Krueger, Felix, Reik, Wolf, Balasubramanian, Shankar

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Loss of 5-hydroxymethylcytosine in cancer: Cause or consequence? von Ficz, Gabriella, Gribben, John G.

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Resetting transcription factor control circuitry toward ground-state pluripotency in human von Takashima, Yasuhiro, Guo, Ge, Loos, Remco, Nichols, Jennifer, Ficz, Gabriella, Krueger, Felix, Oxley, David, Santos, Fatima, Clarke, James, Mansfield, William, Reik, Wolf, Bertone, Paul, Smith, Austin

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Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism von Hahn, Oliver, Grönke, Sebastian, Stubbs, Thomas M, Ficz, Gabriella, Hendrich, Oliver, Krueger, Felix, Andrews, Simon, Zhang, Qifeng, Wakelam, Michael J, Beyer, Andreas, Reik, Wolf, Partridge, Linda

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Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation von Ficz, Gabriella, Branco, Miguel R., Seisenberger, Stefanie, Santos, Fátima, Krueger, Felix, Hore, Timothy A., Marques, C. Joana, Andrews, Simon, Reik, Wolf

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Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms von Hore, Timothy Alexander, von Meyenn, Ferdinand, Ravichandran, Mirunalini, Bachman, Martin, Ficz, Gabriella, Oxley, David, Santos, Fátima, Balasubramanian, Shankar, Jurkowski, Tomasz P., Reik, Wolf

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Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation von Patani, Hemalvi, Rushton, Michael D., Higham, Jonathan, Teijeiro, Saul A., Oxley, David, Cutillas, Pedro, Sproul, Duncan, Ficz, Gabriella

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FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency von Ficz, Gabriella, Hore, Timothy A., Santos, Fátima, Lee, Heather J., Dean, Wendy, Arand, Julia, Krueger, Felix, Oxley, David, Paul, Yu-Lee, Walter, Jörn, Cook, Simon J., Andrews, Simon, Branco, Miguel R., Reik, Wolf

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Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle von Halsall, John A., Andrews, Simon, Krueger, Felix, Rutledge, Charlotte E., Ficz, Gabriella, Reik, Wolf, Turner, Bryan M.

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Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors von Saunderson, Emily A., Stepper, Peter, Gomm, Jennifer J., Hoa, Lily, Morgan, Adrienne, Allen, Michael D., Jones, J. Louise, Gribben, John G., Jurkowski, Tomasz P., Ficz, Gabriella

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Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes von Farthing, Cassandra R, Ficz, Gabriella, Ng, Ray Kit, Chan, Chun-Fung, Andrews, Simon, Dean, Wendy, Hemberger, Myriam, Reik, Wolf

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An shRNA kinase screen identifies regulators of UHRF1 stability and activity in mouse embryonic stem cells von Rushton, Michael D., Saunderson, Emily A., Patani, Hemalvi, Green, Michael R., Ficz, Gabriella

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New insights into mechanisms that regulate DNA methylation patterning von Ficz, Gabriella

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Genome-wide Bisulfite Sequencing in Zygotes Identifies Demethylation Targets and Maps the Contribution of TET3 Oxidation von Peat, Julian R., Dean, Wendy, Clark, Stephen J., Krueger, Felix, Smallwood, Sébastien A., Ficz, Gabriella, Kim, Jong Kyoung, Marioni, John C., Hore, Timothy A., Reik, Wolf

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The Influence of Hydroxylation on Maintaining CpG Methylation Patterns: A Hidden Markov Model Approach von Giehr, Pascal, Kyriakopoulos, Charalampos, Ficz, Gabriella, Wolf, Verena, Walter, Jörn

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Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription von Edelmann, Jennifer, Holzmann, Karlheinz, Tausch, Eugen, Saunderson, Emily A., Jebaraj, Billy M. C., Steinbrecher, Daniela, Dolnik, Anna, Blaette, Tamara J., Landau, Dan A., Saub, Jenny, Estenfelder, Sven, Ibach, Stefan, Cymbalista, Florence, Leblond, Veronique, Delmer, Alain, Bahlo, Jasmin, Robrecht, Sandra, Fischer, Kirsten, Goede, Valentin, Bullinger, Lars, Wu, Catherine J., Mertens, Daniel, Ficz, Gabriella, Gribben, John G., Hallek, Michael, Doehner, Hartmut, Stilgenbauer, Stephan

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A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation von Iurlaro, Mario, Ficz, Gabriella, Oxley, David, Raiber, Eun-Ang, Bachman, Martin, Booth, Michael J, Andrews, Simon, Balasubramanian, Shankar, Reik, Wolf

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Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human von Takashima, Yasuhiro, Guo, Ge, Loos, Remco, Nichols, Jennifer, Ficz, Gabriella, Krueger, Felix, Oxley, David, Santos, Fatima, Clarke, James, Mansfield, William, Reik, Wolf, Bertone, Paul, Smith, Austin

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Low HER2 expression in normal breast epithelium enables dedifferentiation and malignant transformation via chromatin opening von Hayat, Ateequllah, Carter, Edward P, King, Hamish W, Ors, Aysegul, Doe, Aaron, Teijeiro, Saul A, Charrot, Sarah, Godinho, Susana, Cutillas, Pedro, Mohammed, Hisham, Grose, Richard P, Ficz, Gabriella

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