Formation of DNA Adducts by the Anticancer Drug Carboplatin: Different Nucleotide Sequence Preferences in Vitro and in Cells von Blommaert, Frank A, van Dijk-Knijnenburg, Helma C. M, Dijt, Fransje J, den Engelse, Leo, Baan, Robert A, Berends, Frits, Fichtinger-Schepman, Anne Marie J

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Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation von Fichtinger-Schepman, Anne Marie J, Van der Veer, Johannis L, Den Hartog, Jeroen H. J, Lohman, Paul H. M, Reedijk, Jan

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cis-diamminedichloroplatinum(II)-induced DNA adducts in peripheral leukocytes from seven cancer patients: quantitative immunochemical detection of the adduct induction and removal... von FICHTINGER-SCHEPMAN, A. M. J, VAN OOSTEROM, A. T, LOHMAN, P. H. M, BERENDS, F

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Formation and repair of cisplatin-induced adducts to DNA in cultured normal and repair-deficient human fibroblasts von DIJT, F. J, FICHTINGER-SCHEPMAN, M. J, BERENDS, F, REEDIJK, J

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Kinetics of the formation and removal of cisplatin-DNA adducts in blood cells and tumor tissue of cancer patients receiving chemotherapy : comparison with in vitro adduct formation von FICHTINGER-SCHEPMAN, A. M. J, VAN DER VELDE-VISSER, S. D, VAN DIJK-KNIJNENBURG, H. C. M, VAN OOSTEROM, A. T, BAAN, R. A, BERENDS, F

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Relationship between the parameters cellular differentiation, doubling time and platinum accumulation and cisplatin sensitivity in a panel of head and neck cancer cell lines von Welters, Marij J.P., Fichtinger‐Schepman, Anne Marie J., Baan, Robert A., Hermsen, Mario A.J.A., van der Vijgh, Wim J.F., Cloos, Jacqueline, Braakhuis, Boudewijn J.M.

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Effect of cisplatin exposure on platinum accumulation and growth inhibition in human neoplastic and normal squamous epithelial cells of the mucosa of the upper-aerodigestive tract von Braakhuis, Boudewijn J.M, Welters, Marij J.P, Cloos, Jacqueline, Pankras, Jeannette E, Smeets, Serge J, Fichtinger-Schepman, Anne-Marie J

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The formation and repair of cisplatin-DNA adducts in wild-type and cisplatin-resistant L1210 cells: comparison of immunocytochemical determination with detection in isolated DNA von Blommaert, Frank A, Floot, Ben G.J, van Dijk-Knijnenburg, Helma C.M, Berends, Frits, Baan, Robert A, Schornagel, Jan H, den Engelse, Leo, Fichtinger-Schepman, Anne Marie J

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Immunocytochemical detection of interaction products of cis-diamminedichloroplatinum(II) and cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II) with DNA in rodent tissue sectio... von TERHEGGEN, P. M. A. B, FLOOT, B. G. J, SCHERER, E, BEGG, A. C, FICHTINGER-SCHEPMAN, A. M. J, DEN ENGELSE, L

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Characterization of a cisplatin-resistant human ovarian carcinoma cell line expressing cross-resistance to 5-fluorouracil but collateral sensitivity to methotrexate von HILL, B. T, SHELLARD, S. A, HOSKING, L. K, DEMPKE, W. C. M, FICHTINGER, A. M. J, TAKESHI, S, TONE, T, SCANLON, K. J, WHELAN, R. D. H

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Cisplatin–DNA adduct formation in rat spermatozoa and its effect on fetal development von Hooser, Stephen B., van Dijk-Knijnenburg, Wilhelmina C.M., Waalkens-Berendsen, Ine D.H., Smits-van Prooije, Annette E., Snoeij, Niek J., Baan, Robert A., Fichtinger-Schepman, Anne Marie J.

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Platinum concentrations and DNA adduct levels in tumors and organs of cisplatin-treated LOU/M rats inoculated with cisplatin-sensitive or -resistant immunoglobulin M immunocytoma von FICHTINGER-SCHEPMAN, A. M. J, VENDRIK, C. P. J, SCHORNAGEL, J. H, BERENDS, F, VAN DIJK-KNIJNENBURG, W. C. M, DE JONG, W. H, VAN DER MINNEN, A. C. E, CLAESSEN, A. M. E, VAN DER VELDE-VISSER, S. D, DE GROOT, G, WUBS, K. L, STEERENBERG, P. A

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Influence of amifostine on the pharmacokinetics of cisplatin in cancer patients von Korst, A E, van der Sterre, M L, Gall, H E, Fichtinger-Schepman, A M, Vermorken, J B, van der Vijgh, W J

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Effects of the modulating agent WR2721 and its main metabolites on the formation and stability of cisplatin-DNA adducts in vitro in comparison to the effects of thiosulphate and di... von Treskes, Marco, Nijtmans, Leo G.J., J. Fichtinger-Schepman, Anne Marie, van der Vijgh, Wim J.F.

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Differential repair of platinum-DNA adducts in human bladder and testicular tumor continuous cell lines von BEDFORD, P, FICHTINGER-SCHEPMAN, A. M. J, SHELLARD, S. A, WALKER, M. C, MASTERS, J. R. W, HILL, B. T

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Pharmacokinetics of carboplatin with and without amifostine in patients with solid tumors von KORST, A. E. C, VAN DER STERRE, M. L. T, EELTINK, C. M, FICHTINGER-SCHEPMAN, A. M. J, VERMORKEN, J. B, VAN DER VIJGH, W. J. F

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The formation and persistence of carboplatin-DNA adducts in rats von BLOMMAERT, F. A, MICHAEL, C, VAN DIJK-KNIJNENBURG, H. C. M, SCHORNAGEL, J. H, DEN ENGELSE, L, FICHTINGER-SCHEPMAN, A. M. J

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Enhanced dna repair and tolerance of DNA damage associated with resistance to cis-diammine-dichloroplatinum (II) after in vitro exposure of a human teratoma cell line to fractionat... von Hill, Bridget T., Shellard, Sharon A., Hosking, Louise K., Fichtinger-Schepman, Anne Marie J., Bedford, Philip

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Mechanisms associated with the expression of cisplatin resistance in a human ovarian tumor cell line following exposure to fractionated X-irradiation in vitro von Dempke, Wolfram C.M., Shellard, Sharon A., Hosking, Louise K., Fichtinger-Schepman, Anne Marie J., Hill, Bridget T.

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Reaction of the antitumor drug cis-diamminedichloroplatinum(II) with the trinucleotide d(GpApG): identification of the two main products and kinetic aspects of their formation von Van der Veer, Johannis L, Van den Elst, Hans, Den Hartog, Jeroen H. J, Fichtinger-Schepman, Anne Marie J, Reedijk, Jan

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