Physiological control for left ventricular assist devices based on deep reinforcement learning von Fernández‐Zapico, Diego, Peirelinck, Thijs, Deconinck, Geert, Donker, Dirk W., Fresiello, Libera

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Physiological control for left ventricular assist devices based on deep reinforcement learning von Fernández-Zapico, Diego, Peirelinck, Thijs, Deconinck, Geert, Donker, Dirk W, Fresiello, Libero

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Translational relevance of SOS1 targeting for KRAS‐mutant colorectal cancer von Alem, Diego, Yang, Xinrui, Beato, Francisca, Sarcar, Bhaswati, Tassielli, Alexandra F., Dai, Ruifan, Hogenson, Tara L., Park, Margaret A., Jiang, Kun, Cai, Jianfeng, Yuan, Yu, Fernandez‐Zapico, Martin E., Tan, Aik Choon, Fleming, Jason B., Xie, Hao

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RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis von Carr, Ryan M., Vorobyev, Denis, Lasho, Terra, Marks, David L., Tolosa, Ezequiel J., Vedder, Alexis, Almada, Luciana L., Yurcheko, Andrey, Padioleau, Ismael, Alver, Bonnie, Coltro, Giacomo, Binder, Moritz, Safgren, Stephanie L., Horn, Isaac, You, Xiaona, Solary, Eric, Balasis, Maria E., Berger, Kurt, Hiebert, James, Witzig, Thomas, Buradkar, Ajinkya, Graf, Temeida, Valent, Peter, Mangaonkar, Abhishek A., Robertson, Keith D., Howard, Matthew T., Kaufmann, Scott H., Pin, Christopher, Fernandez-Zapico, Martin E., Geissler, Klaus, Droin, Nathalie, Padron, Eric, Zhang, Jing, Nikolaev, Sergey, Patnaik, Mrinal M.

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Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB von Mott, Justin L., Kurita, Satoshi, Cazanave, Sophie C., Bronk, Steven F., Werneburg, Nathan W., Fernandez-Zapico, Martin E.

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ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism von Liu, Mingyang, Yang, Jingxuan, Zhang, Yuqing, Zhou, Zhijun, Cui, Xiaobo, Zhang, Liyang, Fung, Kar-Ming, Zheng, Wei, Allard, Felicia D, Yee, Eric U, Ding, Kai, Wu, Huanwen, Liang, Zhiyong, Zheng, Lei, Fernandez-Zapico, Martin E, Li, Yi-Ping, Bronze, Michael S, Morris, Katherine T, Postier, Russell G, Houchen, Courtney W, Yang, Jing, Li, Min

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Evidence for the existence of an HP1-mediated subcode within the histone code von Lomberk, Gwen, Bensi, Debora, Fernandez-Zapico, Martín E., Urrutia, Raul

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LPCAT1-TERT fusions are uniquely recurrent in epithelioid trophoblastic tumors and positively regulate cell growth von Oliver, Gavin R, Marcano-Bonilla, Sofia, Quist, Jonathan, Tolosa, Ezequiel J, Iguchi, Eriko, Swanson, Amy A, Hoppman, Nicole L, Schwab, Tanya, Sigafoos, Ashley, Prodduturi, Naresh, Voss, Jesse S, Knight, Shannon M, Zhang, Jin, Fadra, Numrah, Urrutia, Raul, Zimmerman, Michael, Egan, Jan B, Bilyeu, Anthony G, Jen, Jin, Veras, Ema, Al-Safi, Rema'a, Block, Matthew, Kerr, Sarah, Fernandez-Zapico, Martin E, Schoolmeester, John K, Klee, Eric W

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ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL von Pietrobono, Silvia, Anichini, Giulia, Sala, Cesare, Manetti, Fabrizio, Almada, Luciana L., Pepe, Sara, Carr, Ryan M., Paradise, Brooke D., Sarkaria, Jann N., Davila, Jaime I., Tofani, Lorenzo, Battisti, Ilaria, Arrigoni, Giorgio, Ying, Li, Zhang, Cheng, Li, Hu, Meves, Alexander, Fernandez-Zapico, Martin E., Stecca, Barbara

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Endoplasmic Reticulum Stress-Activated Transcription Factor ATF6α Requires the Disulfide Isomerase PDIA5 To Modulate Chemoresistance von Higa, Arisa, Taouji, Said, Lhomond, Stéphanie, Jensen, Devon, Fernandez-Zapico, Martin E., Simpson, Jeremy C., Pasquet, Jean-Max, Schekman, Randy, Chevet, Eric

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Tumor-derived GLI1 promotes remodeling of the immune tumor microenvironment in melanoma von Giammona, Alessandro, De Vellis, Chiara, Crivaro, Enrica, Maresca, Luisa, Amoriello, Roberta, Ricci, Federica, Anichini, Giulia, Pietrobono, Silvia, Pease, David R, Fernandez-Zapico, Martin E, Ballerini, Clara, Stecca, Barbara

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Parallel functional annotation of cancer-associated missense mutations in histone methyltransferases von Canning, Ashley J., Viggiano, Susan, Fernandez-Zapico, Martin E., Cosgrove, Michael S.

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Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia von Binder, Moritz, Carr, Ryan M., Lasho, Terra L., Finke, Christy M., Mangaonkar, Abhishek A., Pin, Christopher L., Berger, Kurt R., Mazzone, Amelia, Potluri, Sandeep, Ordog, Tamas, Robertson, Keith D., Marks, David L., Fernandez-Zapico, Martin E., Gaspar-Maia, Alexandre, Patnaik, Mrinal M.

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Reconstitution of human PDAC using primary cells reveals oncogenic transcriptomic features at tumor onset von Xu, Yi, Nipper, Michael H., Dominguez, Angel A., Ye, Zhenqing, Akanuma, Naoki, Lopez, Kevin, Deng, Janice J., Arenas, Destiny, Sanchez, Ava, Sharkey, Francis E., Court, Colin M., Singhi, Aatur D., Wang, Huamin, Fernandez-Zapico, Martin E., Sun, Lu-Zhe, Zheng, Siyuan, Chen, Yidong, Liu, Jun, Wang, Pei

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Mutant K-Ras increases GSK-3β gene expression via an ETS-p300 transcriptional complex in pancreatic cancer von Zhang, J-S, Koenig, A, Harrison, A, Ugolkov, A V, Fernandez-Zapico, M E, Couch, F J, Billadeau, D D

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EGFR Reloaded: Finding New Ways to Shape Pancreatic Cancer Epigenome von LaRue, Kayla C., Fernandez-Zapico, Martin E.

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The transcription factor GLI1 mediates TGFβ1 driven EMT in hepatocellular carcinoma via a SNAI1-dependent mechanism von Zheng, Xin, Vittar, Natalia B Rumie, Gai, Xiaohong, Fernandez-Barrena, Maite G, Moser, Catherine D, Hu, Chunling, Almada, Luciana L, McCleary-Wheeler, Angela L, Elsawa, Sherine F, Vrabel, Anne M, Shire, Abdirashid M, Comba, Andrea, Thorgeirsson, Snorri S, Kim, Youngsoo, Liu, Qingguang, Fernandez-Zapico, Martin E, Roberts, Lewis R

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Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6) von Mazzone, Amelia, Gibbons, Simon J., Bernard, Cheryl E., Nowsheen, Somaira, Middha, Sumit, Almada, Luciana L., Ordog, Tamas, Kendrick, Michael L., Lombardo, KMarie Reid, Shen, K. Robert, Galietta, Luis J. V., Fernandez‐Zapico, Martin E., Farrugia, Gianrico

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GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis von Kurita, S, Mott, J L, Almada, L L, Bronk, S F, Werneburg, N W, Sun, S-Y, Roberts, L R, Fernandez-Zapico, M E, Gores, G J

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Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma von Pereira, Thiago de Almeida, Witek, Rafal P, Syn, Wing-Kin, Choi, Steve S, Bradrick, Shelton, Karaca, Gamze F, Agboola, Kolade M, Jung, Youngmi, Omenetti, Alessia, Moylan, Cynthia A, Yang, Liu, Fernandez-Zapico, Martin E, Jhaveri, Ravi, Shah, Vijay H, Pereira, Fausto E, Diehl, Anna M

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