Identification of Selective Inhibitors of Plasmodium N‑Myristoyltransferase by High-Throughput Screening von Harupa, Anke, De Las Heras, Laura, Colmenarejo, Gonzalo, Lyons-Abbott, Sally, Reers, Alexandra, Caballero Hernandez, Iván, Chung, Chun-Wa, Charter, David, Myler, Peter J, Fernández-Menéndez, Raquel M, Calderón, Félix, Palomo, Sara, Rodríguez, Beatriz, Berlanga, Manuela, Herreros-Avilés, Esperanza, Staker, Bart L, Fernández Álvaro, Elena, Kaushansky, Alexis

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Identification of and Structural Insights into Hit Compounds Targeting N‑Myristoyltransferase for Cryptosporidium Drug Development von Fenwick, Michael K., Reers, Alexandra R., Liu, Yi, Zigweid, Rachael, Sankaran, Banumathi, Shin, Janis, Hulverson, Matthew A., Hammerson, Bradley, Fernández Álvaro, Elena, Myler, Peter J., Kaushansky, Alexis, Van Voorhis, Wesley C., Fan, Erkang, Staker, Bart L.

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The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp von Fernández Álvaro, Elena, Voong Vinh, Phat, de Cozar, Cristina, Willé, David R, Urones, Beatriz, Cortés, Alvaro, Price, Alan, Tran Do Hoang, Nhu, Ha Thanh, Tuyen, McCloskey, Molly, Shaheen, Shareef, Dayao, Denise, Martinot, Amanda, de Mercado, Jaime, Castañeda, Pablo, García-Perez, Adolfo, Singa, Benson, Pavlinac, Patricia, Walson, Judd, Martínez-Martínez, Maria Santos, Arnold, Samuel L M, Tzipori, Saul, Ballell Pages, Lluis, Baker, Stephen

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Correction: The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp von Fernández Álvaro, Elena, Voong Vinh, Phat, de Cozar, Cristina, Willé, David R, Urones, Beatriz, Cortés, Alvaro, Price, Alan, Tran Do Hoang, Nhu, Ha Thanh, Tuyen, McCloskey, Molly, Shaheen, Shareef, Dayao, Denise, Martinot, Amanda, de Mercado, Jaime, Castañeda, Pablo, García-Perez, Adolfo, Singa, Benson, Pavlinac, Patricia, Walson, Judd, Martínez-Martínez, Maria Santos, Arnold, Samuel LM, Tzipori, Saul, Pages, Lluis Ballell, Baker, Stephen

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Antimalarial Chemotherapy: Natural Product Inspired Development of Preclinical and Clinical Candidates with Diverse Mechanisms of Action von Fernández-Álvaro, Elena, Hong, W David, Nixon, Gemma L, O'Neill, Paul M, Calderón, Félix

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Tebipenem as an oral alternative for the treatment of typhoid caused by XDR Salmonella Typhi von Mylona, Elli, Voong Vinh, Phat, Qureshi, Sonia, Karkey, Abhilasha, Dongol, Sabina, Ha Thanh, Tuyen, Walson, Judd, Ballell, Lluis, Fernández Álvaro, Elena, Qamar, Farah, Baker, Stephen

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Lead Optimization of Dehydroemetine for Repositioned Use in Malaria von Panwar, Priyanka, Burusco, Kepa K, Abubaker, Muna, Matthews, Holly, Gutnov, Andrey, Fernández-Álvaro, Elena, Bryce, Richard A, Wilkinson, James, Nirmalan, Niroshini

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Antimalarial Chemotherapy: Natural Product Inspired Development of Preclinical and Clinical Candidates with Diverse Mechanisms of Action: Miniperspective von Fernández-Álvaro, Elena, Hong, W. David, Nixon, Gemma L, O’Neill, Paul M, Calderón, Félix

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Assessing biocatalysis for the synthesis of optically active tetrahydropyrazolo[1,5-α]pyrimidines (THPPs) as novel therapeutic agents von Fernández-Álvaro, Elena, Esquivias, Jorge, Pérez-Sánchez, María, Domínguez de María, Pablo, Remuiñán-Blanco, Modesto J.

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Eine Kombination aus In-vivo-Selektion und Zellsortierung zur Identifizierung enantioselektiver Biokatalysatoren von Fernández-Álvaro, Elena, Snajdrova, Radka, Jochens, Helge, Davids, Timo, Böttcher, Dominique, Bornscheuer, Uwe T.

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Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites von Matralis, Alexios N, Malik, Adnan, Penzo, Maria, Moreno, Inmaculada, Almela, Maria J, Camino, Isabel, Crespo, Benigno, Saadeddin, Anas, Ghidelli-Disse, Sonja, Rueda, Lourdes, Calderon, Felix, Osborne, Simon A, Drewes, Gerard, Böesche, Markus, Fernández-Álvaro, Elena, Martin Hernando, Jose Ignacio, Baker, David A

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A Combination of In Vivo Selection and Cell Sorting for the Identification of Enantioselective Biocatalysts von Fernández-Álvaro, Elena, Snajdrova, Radka, Jochens, Helge, Davids, Timo, Böttcher, Dominique, Bornscheuer, Uwe T.

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The crystal structure of an esterase from the hyperthermophilic microorganism Pyrobaculum calidifontis VA1 explains its enantioselectivity von Palm, Gottfried J., Fernández-Álvaro, Elena, Bogdanović, Xenia, Bartsch, Sebastian, Sczodrok, Jaroslaw, Singh, Rajesh K., Böttcher, Dominique, Atomi, Haruyuki, Bornscheuer, Uwe T., Hinrichs, Winfried

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Reductases: From Natural Diversity to Established Biocatalysis and to Emerging Enzymatic Activities von Fernández‐Álvaro, Elena, de María, Pablo Domínguez

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Eine Kombination aus In‐vivo‐Selektion und Zellsortierung zur Identifizierung enantioselektiver Biokatalysatoren von Fernández‐Álvaro, Elena, Snajdrova, Radka, Jochens, Helge, Davids, Timo, Böttcher, Dominique, Bornscheuer, Uwe T.

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Animal models of efficacy to accelerate drug discovery in malaria von JIMÉNEZ-DÍAZ, MARÍA BELÉN, VIERA, SARA, FERNÁNDEZ-ALVARO, ELENA, ANGULO-BARTUREN, IÑIGO

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Novel inhibitors that target bacterial virulence identified via HTS against intra-macrophage survival of Shigella flexneri von Miljkovic, Marija, Lozano, Sonia, Castellote, Isabel, de Cózar, Cristina, Villegas-Moreno, Ana I, Gamallo, Pablo, Jimenez-Alfaro Martinez, Dolores, Fernández-Álvaro, Elena, Ballell, Lluis, Garcia, George A

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Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites von Matralis, Alexios N, Malik, Adnan, Penzo, Maria, Moreno, Inmaculada, Almela, Maria J, Camino, Isabel, Crespo, Benigno, Saadeddin, Anas, Ghidelli-Disse, Sonja, Rueda, Lourdes, Calderon, Felix, Osborne, Simon A, Drewes, Gerard, Böesche, Markus, Fernández-Álvaro, Elena, Martin Hernando, Jose Ignacio, Baker, David A

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Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target von Alam, Mahmood M., Sanchez-Azqueta, Ana, Janha, Omar, Flannery, Erika L., Mahindra, Amit, Mapesa, Kopano, Char, Aditya B., Sriranganadane, Dev, Brancucci, Nicolas M. B., Antonova-Koch, Yevgeniya, Crouch, Kathryn, Simwela, Nelson Victor, Millar, Scott B., Akinwale, Jude, Mitcheson, Deborah, Solyakov, Lev, Dudek, Kate, Jones, Carolyn, Zapatero, Cleofé, Doerig, Christian, Nwakanma, Davis C., Vázquez, Maria Jesús, Colmenarejo, Gonzalo, Lafuente-Monasterio, Maria Jose, Leon, Maria Luisa, Godoi, Paulo H. C., Elkins, Jon M., Waters, Andrew P., Jamieson, Andrew G., Álvaro, Elena Fernández, Ranford-Cartwright, Lisa C., Marti, Matthias, Winzeler, Elizabeth A., Gamo, Francisco Javier, Tobin, Andrew B.

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Efforts Aimed To Reduce Attrition in Antimalarial Drug Discovery: A Systematic Evaluation of the Current Antimalarial Targets Portfolio von Chaparro, María Jesús, Calderón, Félix, Castañeda, Pablo, Fernández-Alvaro, Elena, Gabarró, Raquel, Gamo, Francisco Javier, Gómez-Lorenzo, María G, Martín, Julio, Fernández, Esther

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