Mre11 Nuclease Activity Has Essential Roles in DNA Repair and Genomic Stability Distinct from ATM Activation von Buis, Jeffrey, Wu, Yipin, Deng, Yibin, Leddon, Jennifer, Westfield, Gerwin, Eckersdorff, Mark, Sekiguchi, JoAnn M., Chang, Sandy, Ferguson, David O.

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Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors von Hartlerode, Andrea J, Morgan, Mary J, Wu, Yipin, Buis, Jeffrey, Ferguson, David O

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Multiple functions of MRN in end-joining pathways during isotype class switching von Stoneham, Trina, Spehalski, Elizabeth, Sekiguchi, JoAnn M, Ferguson, David O, Buis, Jeffrey, Dinkelmann, Maria, Wu, Yipin

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Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation von HINOI, Takao, AKYOL, Aytekin, THEISEN, Brian K, FERGUSON, David O, GREENSON, Joel K, WILLIAMS, Bart O, CHO, Kathleen R, FEARONT, Eric R

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Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution von Li, Yinghua, Li, Bo, Li, Wei, Wang, Yuan, Akgül, Seçkin, Treisman, Daniel M., Heist, Kevin A., Pierce, Brianna R., Hoff, Benjamin, Ho, Cheng-Ying, Ferguson, David O., Rehemtulla, Alnawaz, Zheng, Siyuan, Ross, Brian D., Li, Jun Z., Zhu, Yuan

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Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms von Regal, Joshua A, Festerling, Todd A, Buis, Jeffrey M, Ferguson, David O

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The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation von Yu, Zhenbao, Vogel, Gillian, Coulombe, Yan, Dubeau, Danielle, Spehalski, Elizabeth, Hébert, Josée, Ferguson, David O, Masson, Jean Yves, Richard, Stéphane

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The role of DNA breaks in genomic instability and tumorigenesis von Mills, Kevin D., Ferguson, David O., Alt, Frederick W.

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DNA double strand break repair and chromosomal translocation: lessons from animal models von Ferguson, D O, Alt, F W

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The Essential DNA Damage Response Complex MRN Is Dispensable for the Survival and Function of Purkinje Neurons von Ding, Mingmei, Qing, Xiaobing, Zhang, Guangyu, Baade-Büttner, Carolin, Gruber, Ralph, Lu, Haizhen, Ferguson, David O, Geis, Christian, Wang, Zhao-Qi, Zhou, Zhong-Wei

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Increased Ionizing Radiation Sensitivity and Genomic Instability in the Absence of Histone H2AX von Bassing, Craig H., Chua, Katrin F., Sekiguchi, JoAnn, Suh, Heikyung, Whitlow, Scott R., Fleming, James C., Monroe, Brianna C., Ciccone, David N., Yan, Catherine, Vlasakova, Katerina, Livingston, David M., Ferguson, David O., Scully, Ralph, Alt, Frederick W.

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Unrepaired DNA Breaks in p53-Deficient Cells Lead to Oncogenic Gene Amplification Subsequent to Translocations von Zhu, Chengming, Mills, Kevin D., Ferguson, David O., Lee, Charles, Manis, John, Fleming, James, Gao, Yijie, Morton, Cynthia C., Alt, Frederick W.

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Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation von Jones, Morgan, Osawa, Gail, Regal, Joshua A, Weinberg, Daniel N, Taggart, James, Kocak, Hande, Friedman, Ann, Ferguson, David O, Keegan, Catherine E, Maillard, Ivan

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Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development von Alt, Frederick W, Gao, Yijie, Ferguson, David O, Xie, Wei, Manis, John P, Sekiguchi, JoAnn, Frank, Karen M, Chaudhuri, Jayanta, Horner, James, DePinho, Ronald A

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DNA Ligase IV Deficiency in Mice Leads to Defective Neurogenesis and Embryonic Lethality via the p53 Pathway von Frank, Karen M, Sharpless, Norman E, Gao, Yijie, Sekiguchi, JoAnn M, Ferguson, David O, Zhu, Chengming, Manis, John P, Horner, James, DePinho, Ronald A, Alt, Frederick W

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Multiple roles for MRE11 at uncapped telomeres von Deng, Yibin, Guo, Xiaolan, Chang, Sandy, Ferguson, David O

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The Nonhomologous End-Joining Pathway of DNA Repair Is Required for Genomic Stability and the Suppression of Translocations von Ferguson, David O., Sekiguchi, JoAnn M., Chang, Sandy, Frank, Karen M., Gao, Yijie, DePinho, Ronald A., Alt, Frederick W.

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Mre11 regulates CtIP-dependent double-strand break repair by interaction with CDK2 von Buis, Jeffrey, Stoneham, Trina, Spehalski, Elizabeth, Ferguson, David O

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Defective DNA repair and increased genomic instability in Artemis-deficient murine cells von Rooney, Sean, Alt, Frederick W, Lombard, David, Whitlow, Scott, Eckersdorff, Mark, Fleming, James, Fugmann, Sebastian, Ferguson, David O, Schatz, David G, Sekiguchi, JoAnn

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Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability von Mills, Kevin D, Ferguson, David O, Essers, Jeroen, Eckersdorff, Mark, Kanaar, Roland, Alt, Frederick W

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