389 Combining transcriptomic- and tissue-based immune biomarkers to evaluate GB1275, a CD11b modulator, as a single agent or with pembrolizumab in patients with advanced solid tumo... von Messersmith, Wells, Rasco, Drew, Bono, Johann De, Wang-Gillam, Andrea, Park, Wungki, Nickle, David, Galkin, Anna, Ferguson, Beatrice, Carter, Laura, Zhou, Lei, Dupont, Jakob, Chaney, Marya, Bendell, Johanna, Bruey, Jean-Marie

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Factors Associated With Histologic Response in Adult Patients With Nonalcoholic Steatohepatitis von Loomba, Rohit, Sanyal, Arun J., Kowdley, Kris V., Terrault, Norah, Chalasani, Naga P., Abdelmalek, Manal F., McCullough, Arthur J., Shringarpure, Reshma, Ferguson, Beatrice, Lee, Lois, Chen, Jianfen, Liberman, Alexander, Shapiro, David, Neuschwander-Tetri, Brent A.

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Relationship between three commonly used non‐invasive fibrosis biomarkers and improvement in fibrosis stage in patients with non‐alcoholic steatohepatitis von Chalasani, Naga, Abdelmalek, Manal F., Loomba, Rohit, Kowdley, Kris V., McCullough, Arthur J., Dasarathy, Srinivasan, Neuschwander‐Tetri, Brent A., Terrault, Norah, Ferguson, Beatrice, Shringarpure, Reshma, Shapiro, David, Sanyal, Arun J., Tacke, Frank

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A phase I/II study of GB1275, a first-in-class oral CD11b modulator, alone, and combined with pembrolizumab in specified advanced solid tumors or with chemotherapy in metastatic pa... von Rasco, Drew W., Bendell, Johanna C., Wang-Gillam, Andrea, Park, Wungki, O'Reilly, Eileen Mary, Zhou, Lei, Galkin, Anna, Carter, Laura L, Nickle, David, Li, Jack, Ferguson, Beatrice, Chaney, Marya F., Dupont, Jakob, Messersmith, Wells A.

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Abstract CT247: A phase 1/2 study of GB1275, a first-in-class CD11b modulator, as monotherapy and with an anti-PD-1 antibody in specified advanced solid tumors or with chemotherapy... von Wang-Gillam, Andrea, Rasco, Drew W., Park, Wungki, O'Reilly, Eileen, Messersmith, Wells, DeNardo, David G., Gupta, Vineet, Zhou, Lei, Galkin, Anna, Slee, Debbie, Carter, Laura L., Nickle, David, Tran, Rebecca, Li, Jack, Ferguson, Beatrice, Chaney, Marya F., Salter-Cid, Luisa, Dupont, Jakob, Bendell, Johanna C.

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Relationship Between Three Commonly Used Non-invasive Fibrosis Biomarkers and Improvement in Fibrosis Stage in Patients With NASH von Chalasani, Naga, Abdelmalek, Manal F., Loomba, Rohit, Kowdley, Kris V., McCullough, Arthur J., Dasarathy, Srinivasan, Neuschwander-Tetri, Brent A., Terrault, Norah, Ferguson, Beatrice, Shringarpure, Reshma, Shapiro, David, Sanyal, Arun J.

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388 Preliminary results from KEYNOTE-A36, a study of GB1275, a first-in-class oral CD11b modulator, alone and with pembrolizumab or chemotherapy in specified advanced solid tumors... von Bendell, Johanna, Messersmith, Wells, Rasco, Drew, Wang-Gillam, Andrea, Park, Wungki, Zhou, Lei, Carter, Laura, Bruey, Jean-Marie, Li, Jack, Ferguson, Beatrice, Dupont, Jakob, Chaney, Marya, Bono, Johann De

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880: EVALUATION OF CONTINUOUS-INFUSION HALOPERIDOL FOR REFRACTORY AGITATION/DELIRIUM IN ICU PATIENTS von Adams, Beatrice, Ferguson, Kevin

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Osteosarcoma and soft-tissue sarcomas with an immune infiltrate express PD-L1: relation to clinical outcome and Th1 pathway activation von Wunder, Jay S., Lee, Minji J., Nam, Junghyun, Lau, Beatrice Y., Dickson, Brendan C., Pinnaduwage, Dushanthi, Bull, Shelley B., Ferguson, Peter C., Seto, Andrew, Gokgoz, Nalan, Andrulis, Irene L.

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Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo von Lavezzo, Enrico, Franchin, Elisa, Ciavarella, Constanze, Cuomo-Dannenburg, Gina, Barzon, Luisa, Del Vecchio, Claudia, Rossi, Lucia, Manganelli, Riccardo, Loregian, Arianna, Navarin, Nicolò, Abate, Davide, Sciro, Manuela, Merigliano, Stefano, De Canale, Ettore, Vanuzzo, Maria Cristina, Besutti, Valeria, Saluzzo, Francesca, Onelia, Francesco, Pacenti, Monia, Parisi, Saverio G., Carretta, Giovanni, Donato, Daniele, Flor, Luciano, Cocchio, Silvia, Masi, Giulia, Sperduti, Alessandro, Cattarino, Lorenzo, Salvador, Renato, Nicoletti, Michele, Caldart, Federico, Castelli, Gioele, Nieddu, Eleonora, Labella, Beatrice, Fava, Ludovico, Drigo, Matteo, Gaythorpe, Katy A. M., Brazzale, Alessandra R., Toppo, Stefano, Trevisan, Marta, Baldo, Vincenzo, Donnelly, Christl A., Ferguson, Neil M., Dorigatti, Ilaria, Crisanti, Andrea

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Dextromethorphan as a novel nonopioid adjunctive agent for pain control with medication abortion: A randomized controlled trial von Ferguson, Grace P., Achilles, Sharon L., Meyn, Leslie A., Krajewski, Colleen M., Chappell, Catherine A., Vinekar, Kavita, Chen, Beatrice A.

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Pharmacologic Management of Alcohol Withdrawal Syndrome in Intensive Care Units von Adams, Beatrice, Ferguson, Kevin

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Early Active Mobilization during Mechanical Ventilation in the ICU von Hodgson, Carol L, Bailey, Michael, Bellomo, Rinaldo, Brickell, Kathy, Broadley, Tessa, Buhr, Heidi, Gabbe, Belinda J, Gould, Doug W, Harrold, Meg, Higgins, Alisa M, Hurford, Sally, Iwashyna, Theodore J, Serpa Neto, Ary, Nichol, Alistair D, Presneill, Jeffrey J, Schaller, Stefan J, Sivasuthan, Janani, Tipping, Claire J, Webb, Steven, Young, Paul J

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Identifying actionable variants using next generation sequencing in patients with a historical diagnosis of undifferentiated pleomorphic sarcoma von Lewin, Jeremy, Garg, Swati, Lau, Beatrice Y., Dickson, Brendan C., Traub, Frank, Gokgoz, Nalan, Griffin, Anthony M., Ferguson, Peter C., Andrulis, Irene L., Sim, Hao‐Wen, Kamel‐Reid, Suzanne, Stockley, Tracy L., Siu, Lillian L., Wunder, Jay S., Razak, Albiruni R.A.

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Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologi... von Bielack, Stefan S, Smeland, Sigbjørn, Whelan, Jeremy S, Marina, Neyssa, Jovic, Gordana, Hook, Jane M, Krailo, Mark D, Gebhardt, Mark, Pápai, Zsuzsanna, Meyer, James, Nadel, Helen, Randall, R Lor, Deffenbaugh, Claudia, Nagarajan, Rajaram, Brennan, Bernadette, Letson, G Douglas, Teot, Lisa A, Goorin, Allen, Baumhoer, Daniel, Kager, Leo, Werner, Mathias, Lau, Ching C, Sundby Hall, Kirsten, Gelderblom, Hans, Meyers, Paul, Gorlick, Richard, Windhager, Reinhard, Helmke, Knut, Eriksson, Mikael, Hoogerbrugge, Peter M, Schomberg, Paula, Tunn, Per-Ulf, Kühne, Thomas, Jürgens, Heribert, van den Berg, Henk, Böhling, Tom, Picton, Susan, Renard, Marleen, Reichardt, Peter, Gerss, Joachim, Butterfass-Bahloul, Trude, Morris, Carol, Hogendoorn, Pancras C W, Seddon, Beatrice, Calaminus, Gabriele, Michelagnoli, Maria, Dhooge, Catharina, Sydes, Matthew R, Bernstein, Mark

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Harnessing the diversity of small-scale actors is key to the future of aquatic food systems von Short, Rebecca E., Gelcich, Stefan, Little, David C., Micheli, Fiorenza, Allison, Edward H., Basurto, Xavier, Belton, Ben, Brugere, Cecile, Bush, Simon R., Cao, Ling, Crona, Beatrice, Cohen, Philippa J., Defeo, Omar, Edwards, Peter, Ferguson, Caroline E., Franz, Nicole, Golden, Christopher D., Halpern, Benjamin S., Hazen, Lucie, Hicks, Christina, Johnson, Derek, Kaminski, Alexander M., Mangubhai, Sangeeta, Naylor, Rosamond L., Reantaso, Melba, Sumaila, U. Rashid, Thilsted, Shakuntala H., Tigchelaar, Michelle, Wabnitz, Colette C. C., Zhang, Wenbo

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HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling von Demos-Davies, Kimberly M, Ferguson, Bradley S, Cavasin, Maria A, Mahaffey, Jennifer H, Williams, Sarah M, Spiltoir, Jessica I, Schuetze, Katherine B, Horn, Todd R, Chen, Bo, Ferrara, Claudia, Scellini, Beatrice, Piroddi, Nicoletta, Tesi, Chiara, Poggesi, Corrado, Jeong, Mark Y, McKinsey, Timothy A

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Drosophila Yemanuclein and HIRA cooperate for de novo assembly of H3.3-containing nucleosomes in the male pronucleus von Orsi, Guillermo A, Algazeery, Ahmed, Meyer, Régis E, Capri, Michèle, Sapey-Triomphe, Laure M, Horard, Béatrice, Gruffat, Henri, Couble, Pierre, Aït-Ahmed, Ounissa, Loppin, Benjamin

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Role of the phosphoinositide phosphatase FIG4 gene in familial epilepsy with polymicrogyria von Baulac, Stéphanie, Lenk, Guy M, Dufresnois, Béatrice, Ouled Amar Bencheikh, Bouchra, Couarch, Philippe, Renard, Julie, Larson, Peter A, Ferguson, Cole J, Noé, Eric, Poirier, Karine, Hubans, Christine, Ferreira, Stéphanie, Guerrini, Renzo, Ouazzani, Reda, El Hachimi, Khalid Hamid, Meisler, Miriam H, Leguern, Eric

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Understanding the performance and reliability of NLP tools: a comparison of four NLP tools predicting stroke phenotypes in radiology reports von Casey, Arlene, Davidson, Emma, Grover, Claire, Tobin, Richard, Grivas, Andreas, Zhang, Huayu, Schrempf, Patrick, O'Neil, Alison Q, Lee, Liam, Walsh, Michael, Pellie, Freya, Ferguson, Karen, Cvoro, Vera, Wu, Honghan, Whalley, Heather, Mair, Grant, Whiteley, William, Alex, Beatrice

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