Discovery and SAR of JTE-151: A Novel RORγ Inhibitor for Clinical Development von Maeba, Takaki, Hirata, Kazuyuki, Kotoku, Masayuki, Seki, Noriyoshi, Maeda, Katsuya, Hirashima, Shintaro, Yamanaka, Hiroshi, Sakai, Takayuki, Obika, Shingo, Hori, Akimi, Hara, Yoshinori, Noji, Satoru, Suwa, Yoshihiro, Yokota, Masahiro, Fujioka, Shingo, Yamaguchi, Takayuki, Katsuda, Yoshiaki, Hata, Takahiro, Miyagawa, Naoki, Arita, Kojo, Nomura, Yukihiro, Taniguchi, Toshio, Asahina, Kota, Aratsu, Yusuke, Naka, Yuichi, Adachi, Tsuyoshi, Nomura, Akihiro, Akai, Shota, Oshida, Shin-ichi, Pai, Sudhakar, Crowe, Paul, Bradley, Erin, Steensma, Ruo, Tao, Haiyan, Fenn, Morgan, Babine, Robert, Li, Xiaolin, Thacher, Scott, Soeta, Takahiro, Ukaji, Yutaka, Shiozaki, Makoto

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SAR Exploration Guided by LE and Fsp(3): Discovery of a Selective and Orally Efficacious RORγ Inhibitor von Hirata, Kazuyuki, Kotoku, Masayuki, Seki, Noriyoshi, Maeba, Takaki, Maeda, Katsuya, Hirashima, Shintaro, Sakai, Takayuki, Obika, Shingo, Hori, Akimi, Hase, Yasunori, Yamaguchi, Takayuki, Katsuda, Yoshiaki, Hata, Takahiro, Miyagawa, Naoki, Arita, Kojo, Nomura, Yukihiro, Asahina, Kota, Aratsu, Yusuke, Kamada, Masafumi, Adachi, Tsuyoshi, Noguchi, Masato, Doi, Satoki, Crowe, Paul, Bradley, Erin, Steensma, Ruo, Tao, Haiyan, Fenn, Morgan, Babine, Robert, Li, Xiaolin, Thacher, Scott, Hashimoto, Hiromasa, Shiozaki, Makoto

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Ternary complex of human ROR[gamma] ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment von Noguchi, Masato, Nomura, Akihiro, Murase, Ken, Doi, Satoki, Yamaguchi, Keishi, Hirata, Kazuyuki, Shiozaki, Makoto, Hirashima, Shintaro, Kotoku, Masayuki, Yamaguchi, Takayuki, Katsuda, Yoshiaki, Steensma, Ruo, Li, Xioalin, Tao, Haiyan, Tse, Bruno, Fenn, Morgan, Babine, Robert, Bradley, Erin, Crowe, Paul, Thacher, Scott, Adachi, Tsuyoshi, Kamada, Masafumi

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Ternary complex of human RORγ ligand‐binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment von Noguchi, Masato, Nomura, Akihiro, Murase, Ken, Doi, Satoki, Yamaguchi, Keishi, Hirata, Kazuyuki, Shiozaki, Makoto, Hirashima, Shintaro, Kotoku, Masayuki, Yamaguchi, Takayuki, Katsuda, Yoshiaki, Steensma, Ruo, Li, Xioalin, Tao, Haiyan, Tse, Bruno, Fenn, Morgan, Babine, Robert, Bradley, Erin, Crowe, Paul, Thacher, Scott, Adachi, Tsuyoshi, Kamada, Masafumi

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SAR Exploration Guided by LE and Fsp3: Discovery of a Selective and Orally Efficacious RORγ Inhibitor von Hirata, Kazuyuki, Kotoku, Masayuki, Seki, Noriyoshi, Maeba, Takaki, Maeda, Katsuya, Hirashima, Shintaro, Sakai, Takayuki, Obika, Shingo, Hori, Akimi, Hase, Yasunori, Yamaguchi, Takayuki, Katsuda, Yoshiaki, Hata, Takahiro, Miyagawa, Naoki, Arita, Kojo, Nomura, Yukihiro, Asahina, Kota, Aratsu, Yusuke, Kamada, Masafumi, Adachi, Tsuyoshi, Noguchi, Masato, Doi, Satoki, Crowe, Paul, Bradley, Erin, Steensma, Ruo, Tao, Haiyan, Fenn, Morgan, Babine, Robert, Li, Xiaolin, Thacher, Scott, Hashimoto, Hiromasa, Shiozaki, Makoto

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SAR Exploration Guided by LE and Fsp 3 : Discovery of a Selective and Orally Efficacious RORγ Inhibitor von Hirata, Kazuyuki, Kotoku, Masayuki, Seki, Noriyoshi, Maeba, Takaki, Maeda, Katsuya, Hirashima, Shintaro, Sakai, Takayuki, Obika, Shingo, Hori, Akimi, Hase, Yasunori, Yamaguchi, Takayuki, Katsuda, Yoshiaki, Hata, Takahiro, Miyagawa, Naoki, Arita, Kojo, Nomura, Yukihiro, Asahina, Kota, Aratsu, Yusuke, Kamada, Masafumi, Adachi, Tsuyoshi, Noguchi, Masato, Doi, Satoki, Crowe, Paul, Bradley, Erin, Steensma, Ruo, Tao, Haiyan, Fenn, Morgan, Babine, Robert, Li, Xiaolin, Thacher, Scott, Hashimoto, Hiromasa, Shiozaki, Makoto

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Updates in the treatment of asthma in pediatrics: A review for pharmacists von Smith, Tara, Mills, Kimberly, Cober, M Petrea, Fenn, 3rd, Norman E, Hill, Carolyn, King, Morgan, Pauley, Jennifer L, Eiland, Lea, Sierra, Caroline, Omecene, Nicole E

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Effect of Differing Orientation and Magnitude of Femoral Torsion on Outcomes and Achievement of the MCID and PASS at 5 Years After Hip Arthroscopy for Femoroacetabular Impingement... von Alter, Thomas D., Fenn, Thomas W., Kaplan, Daniel J., Rice, Morgan W., Nho, Shane J.

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Labral Augmentation With Either Iliotibial Band Allograft or Dermis Allograft Perform Similarly Regarding Peak Force, Displacement, and Work to Labral Repair in Suction Seal Restor... von Kaplan, Daniel J., Fenn, Thomas W., Gursoy, Safa, Mameri, Enzo S., Rice, Morgan W., Chapman, Reagan S., Shewman, Elizabeth F., Nho, Shane J.

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Female and Male Patients Achieve Similar Improvement, Outcomes, and Survivorship After Hip Arthroscopy With Labral and Capsular Repair for Femoroacetabular Impingement Syndrome at... von Larson, Jordan H., Kazi, Omair, Beals, Corey, Alvero, Alexander, Kaplan, Daniel J., Fenn, Thomas W., Brusalis, Christopher, Allahabadi, Sachin, Morgan, Vince, Nho, Shane J.

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Just DOAC: Use of direct-acting oral anticoagulants in pediatrics von Mills, Kimberly, Hill, Carolyn, King, Morgan, Pauley, Jennifer L, Cober, M Petrea, Fenn, Norman E, Omecene, Nicole E, Smith, Tara, Sierra, Caroline M

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The Influence Of Habitual, Device-Measured Sleep Duration On Baseline Computerized Neurocognitive Performance And Concussion Symptoms: 263 von Anderson, Morgan, Kuenze, Christopher, Pivarnik, James M., Fenn, Kimberly M., Covassin, Tracey

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The Influence Of Habitual, Device-Measured Sleep Duration On Baseline Computerized Neurocognitive Performance And Concussion Symptoms: 263 von Anderson, Morgan, Kuenze, Christopher, Pivarnik, James M., Fenn, Kimberly M., Covassin, Tracey

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Defining the Minimal Clinically Important Difference (MCID) and Patient Acceptable Symptom State (PASS) at 2 years following open gluteus medius and/or minimus repair von Rice, Morgan W, Browning, Robert B, Fenn, Thomas W, Hevesi, Mario, Nho, Shane J

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Three-Grade Magnetic Resonance Imaging–Based Gluteus Medius and/or Minimus Tear Classification System Provides Excellent Inter-Rater Reliability von Browning, Robert B., Fenn, Thomas W., Allahabadi, Sachin, Rice, Morgan W., Swindell, Hasani W., Ebersole, John W., Nho, Shane J.

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A role for STEAP2 in prostate cancer progression von Whiteland, Helen, Spencer-Harty, Samantha, Morgan, Claire, Kynaston, Howard, Thomas, David Hywel, Bose, Pradeep, Fenn, Neil, Lewis, Paul, Jenkins, Spencer, Doak, Shareen H.

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CD200 is overexpressed in the pancreatic tumor microenvironment and predictive of overall survival von Wedig, Jessica, Jasani, Shrina, Mukherjee, Debasmita, Lathrop, Hannah, Matreja, Priya, Pfau, Timothy, D’Alesio, Liliana, Guenther, Abigail, Fenn, Lexie, Kaiser, Morgan, Torok, Molly A., McGue, Jake, Sizemore, Gina M., Noonan, Anne M., Dillhoff, Mary E., Blaser, Bradley W., Frankel, Timothy L., Culp, Stacey, Hart, Phil A., Cruz-Monserrate, Zobeida, Mace, Thomas A.

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Determinants of survival following pelvic exenteration for primary rectal cancer von Radwan, R. W., Jones, H. G., Rawat, N., Davies, M., Evans, M. D., Harris, D. A., Beynon, J.

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Multivisceral resection for primary locally advanced rectal carcinoma von Harris, D. A., Davies, M., Lucas, M. G., Drew, P., Carr, N. D., Beynon, J.

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Putative prognostic epithelial-to-mesenchymal transition biomarkers for aggressive prostate cancer von Whiteland, Helen, Spencer-Harty, Samantha, Thomas, David Hywel, Davies, Christine, Morgan, Claire, Kynaston, Howard, Bose, Pradeep, Fenn, Neil, Lewis, Paul D., Bodger, Owen, Jenkins, Spencer, Doak, Shareen H.

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