Canakinumab (ACZ885, a fully human IgG1 anti-IL-1β mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS) von Kuemmerle-Deschner, Jasmin B, Ramos, Eduardo, Blank, Norbert, Roesler, Joachim, Felix, Sandra D, Jung, Thomas, Stricker, Kirstin, Chakraborty, Abhijit, Tannenbaum, Stacey, Wright, Andrew M, Rordorf, Christiane

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Canakinumab von Kuemmerle-Deschner, Jasmin B, Ramos, Eduardo, Blank, Norbert, Roesler, Joachim, Felix, Sandra D, Jung, Thomas, Stricker, Kirstin, Chakraborty, Abhijit, Tannenbaum, Stacey, Wright, Andrew M, Rordorf, Christiane

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Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain von Kramer, Jan S, Woltersdorf, Stefano, Duflot, Thomas, Hiesinger, Kerstin, Lillich, Felix F, Knöll, Felix, Wittmann, Sandra K, Klingler, Franca-M, Brunst, Steffen, Chaikuad, Apirat, Morisseau, Christophe, Hammock, Bruce D, Buccellati, Carola, Sala, Angelo, Rovati, G. Enrico, Leuillier, Matthieu, Fraineau, Sylvain, Rondeaux, Julie, Hernandez-Olmos, Victor, Heering, Jan, Merk, Daniel, Pogoryelov, Denys, Steinhilber, Dieter, Knapp, Stefan, Bellien, Jeremy, Proschak, Ewgenij

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Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy von Prondzynski, Maksymilian, Lemoine, Marc D, Zech, Antonia TL, Horváth, András, Di Mauro, Vittoria, Koivumäki, Jussi T, Kresin, Nico, Busch, Josefine, Krause, Tobias, Krämer, Elisabeth, Schlossarek, Saskia, Spohn, Michael, Friedrich, Felix W, Münch, Julia, Laufer, Sandra D, Redwood, Charles, Volk, Alexander E, Hansen, Arne, Mearini, Giulia, Catalucci, Daniele, Meyer, Christian, Christ, Torsten, Patten, Monica, Eschenhagen, Thomas, Carrier, Lucie

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Unpacking ecosystem service bundles: Towards predictive mapping of synergies and trade-offs between ecosystem services von Spake, Rebecca, Lasseur, Rémy, Crouzat, Emilie, Bullock, James M., Lavorel, Sandra, Parks, Katherine E., Schaafsma, Marije, Bennett, Elena M., Maes, Joachim, Mulligan, Mark, Mouchet, Maud, Peterson, Garry D., Schulp, Catharina J.E., Thuiller, Wilfried, Turner, Monica G., Verburg, Peter H., Eigenbrod, Felix

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Spectral Domain Optical Coherence Tomography Imaging of Geographic Atrophy Margins von Bearelly, Srilaxmi, MD, MHS, Chau, Felix Y., MD, Koreishi, Anjum, BSE, Stinnett, Sandra S., DrPH, Izatt, Joseph A., PhD, Toth, Cynthia A., MD

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Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation von Healey, Jeff S., Lopes, Renato D., Granger, Christopher B., Alings, Marco, Rivard, Lena, McIntyre, William F., Atar, Dan, Birnie, David H., Boriani, Giuseppe, Camm, A. John, Conen, David, Erath, Julia W., Gold, Michael R., Hohnloser, Stefan H., Ip, John, Kautzner, Josef, Kutyifa, Valentina, Linde, Cecilia, Mabo, Philippe, Mairesse, Georges, Benezet Mazuecos, Juan, Cosedis Nielsen, Jens, Philippon, Francois, Proietti, Marco, Sticherling, Christian, Wong, Jorge A., Wright, David J., Zarraga, Ignatius G., Coutts, Shelagh B., Kaplan, Andrew, Pombo, Marta, Ayala-Paredes, Felix, Xu, Lizhen, Simek, Kim, Nevills, Sandra, Mian, Rajibul, Connolly, Stuart J.

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The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress von Backes, Sandra, Bykov, Yury S., Flohr, Tamara, Räschle, Markus, Zhou, Jialin, Lenhard, Svenja, Krämer, Lena, Mühlhaus, Timo, Bibi, Chen, Jann, Cosimo, Smith, Justin D., Steinmetz, Lars M., Rapaport, Doron, Storchová, Zuzana, Schuldiner, Maya, Boos, Felix, Herrmann, Johannes M.

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Germline C1GALT1C1 mutation causes a multisystem chaperonopathy von Erger, Florian, Aryal, Rajindra P, Reusch, Björn, Matsumoto, Yasuyuki, Meyer, Robert, Zeng, Junwei, Knopp, Cordula, Noel, Maxence, Muerner, Lukas, Wenzel, Andrea, Kohl, Stefan, Tschernoster, Nikolai, Rappl, Gunter, Rouvet, Isabelle, Schröder-Braunstein, Jutta, Seibert, Felix S, Thiele, Holger, Häusler, Martin G, Weber, Lutz T, Büttner-Herold, Maike, Elbracht, Miriam, Cummings, Sandra F, Altmüller, Janine, Habbig, Sandra, Cummings, Richard D, Beck, Bodo B

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Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy von Prondzynski, Maksymilian, Lemoine, Marc D, Zech, Antonia TL, Horváth, András, Di Mauro, Vittoria, Koivumäki, Jussi T, Kresin, Nico, Busch, Josefine, Krause, Tobias, Krämer, Elisabeth, Schlossarek, Saskia, Spohn, Michael, Friedrich, Felix W, Münch, Julia, Laufer, Sandra D, Redwood, Charles, Volk, Alexander E, Hansen, Arne, Mearini, Giulia, Catalucci, Daniele, Meyer, Christian, Christ, Torsten, Patten, Monica, Eschenhagen, Thomas, Carrier, Lucie

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A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1 von Hai, Ling, Hoffmann, Dirk C., Wagener, Robin J., Azorin, Daniel D., Hausmann, David, Xie, Ruifan, Huppertz, Magnus-Carsten, Hiblot, Julien, Sievers, Philipp, Heuer, Sophie, Ito, Jakob, Cebulla, Gina, Kourtesakis, Alexandros, Kaulen, Leon D., Ratliff, Miriam, Mandelbaum, Henriette, Jung, Erik, Jabali, Ammar, Horschitz, Sandra, Ernst, Kati J., Reibold, Denise, Warnken, Uwe, Venkataramani, Varun, Will, Rainer, Suvà, Mario L., Herold-Mende, Christel, Sahm, Felix, Winkler, Frank, Schlesner, Matthias, Wick, Wolfgang, Kessler, Tobias

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Consensus for EGFR Mutation Testing in Non-small Cell Lung Cancer: Results from a European Workshop von Pirker, Robert, Herth, Felix J.F., Kerr, Keith M., Filipits, Martin, Taron, Miquel, Gandara, David, Hirsch, Fred R., Grunenwald, Dominique, Popper, Helmut, Smit, Egbert, Dietel, Manfred, Marchetti, Antonio, Manegold, Christian, Schirmacher, Peter, Thomas, Michael, Rosell, Rafael, Cappuzzo, Federico, Stahel, Rolf

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Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly von Li, Hongjie, Janssens, Jasper, De Waegeneer, Maxime, Kolluru, Sai Saroja, Davie, Kristofer, Gardeux, Vincent, Saelens, Wouter, David, Fabrice P A, Brbić, Maria, Spanier, Katina, Leskovec, Jure, McLaughlin, Colleen N, Xie, Qijing, Jones, Robert C, Brueckner, Katja, Shim, Jiwon, Tattikota, Sudhir Gopal, Schnorrer, Frank, Rust, Katja, Nystul, Todd G, Carvalho-Santos, Zita, Ribeiro, Carlos, Pal, Soumitra, Mahadevaraju, Sharvani, Przytycka, Teresa M, Allen, Aaron M, Goodwin, Stephen F, Berry, Cameron W, Fuller, Margaret T, White-Cooper, Helen, Matunis, Erika L, DiNardo, Stephen, Galenza, Anthony, O'Brien, Lucy Erin, Dow, Julian A T, Jasper, Heinrich, Oliver, Brian, Perrimon, Norbert, Deplancke, Bart, Quake, Stephen R, Luo, Liqun, Aerts, Stein, Agarwal, Devika, Ahmed-Braimah, Yasir, Arbeitman, Michelle, Ariss, Majd M, Augsburger, Jordan, Ayush, Kumar, Baker, Catherine C, Banisch, Torsten, Birker, Katja, Bodmer, Rolf, Bolival, Benjamin, Brantley, Susanna E, Brill, Julie A, Brown, Nora C, Buehner, Norene A, Cai, Xiaoyu Tracy, Cardoso-Figueiredo, Rita, Casares, Fernando, Chang, Amy, Clandinin, Thomas R, Crasta, Sheela, Desplan, Claude, Detweiler, Angela M, Dhakan, Darshan B, Donà, Erika, Engert, Stefanie, Floc'hlay, Swann, George, Nancy, González-Segarra, Amanda J, Groves, Andrew K, Gumbin, Samantha, Guo, Yanmeng, Harris, Devon E, Heifetz, Yael, Holtz, Stephen L, Horns, Felix, Hudry, Bruno, Hung, Ruei-Jiun, Jan, Yuh Nung, Jaszczak, Jacob S, Jefferis, Gregory S X E, Karkanias, Jim, Karr, Timothy L, Katheder, Nadja Sandra, Kezos, James, Kim, Anna A, Kim, Seung K, Kockel, Lutz, Konstantinides, Nikolaos, Kornberg, Thomas B, Krause, Henry M, Labott, Andrew Thomas, Laturney, Meghan, Lehmann, Ruth, Leinwand, Sarah, Li, Jiefu, Li, Joshua Shing Shun, Li, Kai

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Autonomous rhythmic activity in glioma networks drives brain tumour growth von Hausmann, David, Hoffmann, Dirk C., Venkataramani, Varun, Jung, Erik, Horschitz, Sandra, Tetzlaff, Svenja K., Jabali, Ammar, Hai, Ling, Kessler, Tobias, Azoŕin, Daniel D., Weil, Sophie, Kourtesakis, Alexandros, Sievers, Philipp, Habel, Antje, Breckwoldt, Michael O., Karreman, Matthia A., Ratliff, Miriam, Messmer, Julia M., Yang, Yvonne, Reyhan, Ekin, Wendler, Susann, Löb, Cathrin, Mayer, Chanté, Figarella, Katherine, Osswald, Matthias, Solecki, Gergely, Sahm, Felix, Garaschuk, Olga, Kuner, Thomas, Koch, Philipp, Schlesner, Matthias, Wick, Wolfgang, Winkler, Frank

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Impact of intracoronary bone marrow cell therapy on left ventricular function in the setting of ST-segment elevation myocardial infarction: a collaborative meta-analysis von Delewi, Ronak, Hirsch, Alexander, Tijssen, Jan G, Schächinger, Volker, Wojakowski, Wojciech, Roncalli, Jérôme, Aakhus, Svend, Erbs, Sandra, Assmus, Birgit, Tendera, Michal, Goekmen Turan, R, Corti, Roberto, Henry, Tim, Lemarchand, Patricia, Lunde, Ketil, Cao, Feng, Huikuri, Heikki V, Sürder, Daniel, Simari, Robert D, Janssens, Stefan, Wollert, Kai C, Plewka, Michal, Grajek, Stefan, Traverse, Jay H, Zijlstra, Felix, Piek, Jan J

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Non-bee insects are important contributors to global crop pollination von Rader, Romina, Bartomeus, Ignasi, Garibaldi, Lucas A., Garratt, Michael P. D., Howlett, Brad G., Winfree, Rachael, Cunningham, Saul A., Mayfield, Margaret M., Arthur, Anthony D., Andersson, Georg K. S., Bommarco, Riccardo, Brittain, Claire, Carvalheiro, Luísa G., Chacoff, Natacha P., Entling, Martin H., Foully, Benjamin, Freitas, Breno M., Gemmill-Herren, Barbara, Ghazoul, Jaboury, Griffin, Sean R., Gross, Caroline L., Herbertsson, Lina, Herzog, Felix, Hipólito, Juliana, Jaggar, Sue, Jauker, Frank, Klein, Alexandra-Maria, Kleijn, David, Krishnan, Smitha, Lemos, Camila Q., Lindström, Sandra A. M., Mandelik, Yael, Monteiro, Victor M., Nelson, Warrick, Nilsson, Lovisa, Pattemore, David E., de O. Pereira, Natália, Pisanty, Gideon, Potts, Simon G., Reemer, Menno, Rundlöf, Maj, Sheffield, Cory S., Scheper, Jeroen, Schüepp, Christof, Smith, Henrik G., Stanley, Dara A., Stout, Jane C., Szentgyörgyi, Hajnalka, Taki, Hisatomo, Vergara, Carlos H., Viana, Blandina F., Woyciechowski, Michal

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Focal Irradiation and Systemic TGFβ Blockade in Metastatic Breast Cancer von Formenti, Silvia C, Lee, Percy, Adams, Sylvia, Goldberg, Judith D, Li, Xiaochun, Xie, Mike W, Ratikan, Josephine A, Felix, Carol, Hwang, Lin, Faull, Kym F, Sayre, James W, Hurvitz, Sara, Glaspy, John A, Comin-Anduix, Begoña, Demaria, Sandra, Schaue, Dörthe, McBride, William H

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Changes in the tumour microenvironment mark the transition from serous borderline tumour to low‐grade serous carcinoma von Vallejos, Rodrigo, Zhantuyakova, Almira, Negri, Gian Luca, Martin, Spencer D, Spencer, Sandra E, Thornton, Shelby, Leung, Samuel, Lynch, Branden, Qin, Yimei, Chow, Christine, Liang, Brooke, Zdravko, Sabrina, Douglas, J Maxwell, Milne, Katy, Mateyko, Bridget, Nelson, Brad H, Howitt, Brooke E, Kommoss, Felix KF, Horn, Lars‐Christian, Hoang, Lien, Singh, Naveena, Morin, Gregg B, Huntsman, David G, Cochrane, Dawn

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Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity von Cyrta, Joanna, Augspach, Anke, De Filippo, Maria Rosaria, Prandi, Davide, Thienger, Phillip, Benelli, Matteo, Cooley, Victoria, Bareja, Rohan, Wilkes, David, Chae, Sung-Suk, Cavaliere, Paola, Dephoure, Noah, Uldry, Anne-Christine, Lagache, Sophie Braga, Roma, Luca, Cohen, Sandra, Jaquet, Muriel, Brandt, Laura P., Alshalalfa, Mohammed, Puca, Loredana, Sboner, Andrea, Feng, Felix, Wang, Shangqian, Beltran, Himisha, Lotan, Tamara, Spahn, Martin, Kruithof-de Julio, Marianna, Chen, Yu, Ballman, Karla V., Demichelis, Francesca, Piscuoglio, Salvatore, Rubin, Mark A.

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Genomic mechanisms of climate adaptation in polyploid bioenergy switchgrass von Lovell, John T., MacQueen, Alice H., Mamidi, Sujan, Bonnette, Jason, Jenkins, Jerry, Napier, Joseph D., Sreedasyam, Avinash, Healey, Adam, Session, Adam, Shu, Shengqiang, Barry, Kerrie, Bonos, Stacy, Boston, LoriBeth, Daum, Christopher, Deshpande, Shweta, Ewing, Aren, Grabowski, Paul P., Haque, Taslima, Harrison, Melanie, Jiang, Jiming, Kudrna, Dave, Lipzen, Anna, Pendergast, Thomas H., Plott, Chris, Qi, Peng, Saski, Christopher A., Shakirov, Eugene V., Sims, David, Sharma, Manoj, Sharma, Rita, Stewart, Ada, Singan, Vasanth R., Tang, Yuhong, Thibivillier, Sandra, Webber, Jenell, Weng, Xiaoyu, Williams, Melissa, Wu, Guohong Albert, Yoshinaga, Yuko, Zane, Matthew, Zhang, Li, Zhang, Jiyi, Behrman, Kathrine D., Boe, Arvid R., Fay, Philip A., Fritschi, Felix B., Jastrow, Julie D., Lloyd-Reilley, John, Martínez-Reyna, Juan Manuel, Matamala, Roser, Mitchell, Robert B., Rouquette, Francis M., Ronald, Pamela, Saha, Malay, Tobias, Christian M., Udvardi, Michael, Wing, Rod A., Wu, Yanqi, Bartley, Laura E., Casler, Michael, Devos, Katrien M., Lowry, David B., Rokhsar, Daniel S., Grimwood, Jane, Juenger, Thomas E., Schmutz, Jeremy

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