Inhibitors of TLR-9 Act on Multiple Cell Subsets in Mouse and Man In Vitro and Prevent Death In Vivo from Systemic Inflammation von Duramad, Omar, Fearon, Karen L, Chang, Bonnie, Chan, Jean H, Gregorio, Josh, Coffman, Robert L, Barrat, Franck J

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IL-10 regulates plasmacytoid dendritic cell response to CpG-containing immunostimulatory sequences von Duramad, Omar, Fearon, Karen L., Chan, Jean H., Kanzler, Holger, Marshall, Jason D., Coffman, Robert L., Barrat, Franck J.

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Superior activity of the type C class of ISS in vitro and in vivo across multiple species von Marshall, Jason D, Fearon, Karen L, Higgins, Debbie, Hessel, Edith M, Kanzler, Holger, Abbate, Christi, Yee, Priscilla, Gregorio, Josh, Cruz, Tracy Dela, Lizcano, Jennifer O, Zolotorev, Alya, McClure, Hazel M, Brasky, Kathleen M, Murthy, Krishna K, Coffman, Robert L, Nest, Gary Van

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Novel chimeric immunomodulatory compounds containing short CpG oligodeoxyribonucleotides have differential activities in human cells von Marshall, Jason D., Hessel, Edith M., Gregorio, Josh, Abbate, Christina, Yee, Priscilla, Chu, Mabel, Nest, Gary Van, Coffman, Robert L., Fearon, Karen L.

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N3‘→P5‘ Oligodeoxyribonucleotide Phosphoramidates:  A New Method of Synthesis Based on a Phosphoramidite Amine-Exchange Reaction von Nelson, Jeffrey S, Fearon, Karen L, Nguyen, Mark Q, McCurdy, Sarah N, Frediani, Jeff E, Foy, Michael F, Hirschbein, Bernard L

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Synthesis of Oligo(Deoxyribonucleoside Phosphorodithioate)s by the Dithiaphospholane Approach von Okruszek, Andrzej, Sierzcha-la, Agnieszka, Fearon, Karen L, Stec, Wojciech J

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Polymyxin B enhances ISS-mediated immune responses across multiple species von Marshall, Jason D., Higgins, Debbie, Abbate, Christi, Yee, Priscilla, Teshima, Glen, Ott, Gary, dela Cruz, Tracy, Passmore, David, Fearon, Karen L., Tuck, Stephen, Van Nest, Gary

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IMMUNOSTIMULATORY SEQUENCE OLIGONUCLEOTIDES AND METHODS OF USING THE SAME von Dina, Dino, Fearon, Karen L, Marshall, Jason

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Immunostimulatory sequence oligonucleotides and methods of using the same von Dina, Dino, Fearon, Karen L, Marshall, Jason

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IMMUNOSTIMULATORY SEQUENCE OLIGONUCLEOTIDES AND METHODS OF USING THE SAME von DINA, Dino, MARSHALL, Jason, FEARON, Karen L

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Immunostimulatory sequence oligonucleotides and methods of using the same von Dina, Dino, Fearon, Karen L, Marshall, Jason

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Bis(O,O-diisopropoxy phosphinothioyl) disulfide - a highly efficient sulfurizing reagent for cost-effective synthesis of oligo(nucleoside phosphorothioate)s von Stec, Wojciech J., Uznanski, Bogdan, Wilk, Andrzej, Hirschbein, Bernard L., Fearon, Karen L., Bergot, B.John

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Human toll-like receptor inhibitors and methods of use thereof von Guiducci Cristiana, Barrat Franck, Fearon Karen L

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Investigation of the ‘n–1’ impurity in phosphorothioate oligodeoxynucleotides synthesized by the solid-phase β-cyanoethyl phosphoramidite method using stepwise sulfurization von Fearon, Karen L., Stults, John T., Bergot, B.John, Christensen, Laura M., Raible, Annette M.

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HUMAN TOLL-LIKE RECEPTOR INHIBITORS AND METHODS OF USE THEREOF von GUIDUCCI, Cristiana, FEARON, Karen, L, BARRAT, Franck

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COMPLEXES OF A SHORT CPG-CONTAINING OLIGONUCLEOTIDE BOUND TO THE SURFACE OF A SOLID PHASE MICROCARRIER AND METHODS FOR USE THEREOF von FEARON, KAREN L, DINA, DINO

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IMMUNOSTIMULATORY SEQUENCE OLIGONUCLEOTIDES AND METHODS OF USING THE SAME von FEARON Karen L, DINA Dino, MARSHALL Jason

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An improved synthesis of oligodeoxynucleotide N3′→P5′ phosphoramidates and their chimera using hindered phosphoramidite monomers and a novel handle for reverse phase purification... von Fearon, Karen L., Hirschbein, Bernard L., Nelson, Jeffrey S., Foy, Michael F., Nguyen, Mark Q., McCurdy, Sarah N., Frediani, Jeff E., DeDionisio, Lawrence A., Raible, Annette M., Cagle, E. Neil, Okruszek, Andrzej, Boyd, Vicky

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IMMUNOSTIMULATORY SEQUENCE OLIGONUCLEOTIDES AND METHODS OF USING THE SAME von DINO DINA, KAREN L. FEARON, JASON MARSHALL

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An improved method for the synthesis of N3′→P5′ phosphoramidate oligonucleotides von McCurdy, Sarah N., Nelson, Jeffrey S., Hirschbein, Bernard L., Fearon, Karen L.

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