Inhibitors of TLR-9 Act on Multiple Cell Subsets in Mouse and Man In Vitro and Prevent Death In Vivo from Systemic Inflammation von Duramad, Omar, Fearon, Karen L, Chang, Bonnie, Chan, Jean H, Gregorio, Josh, Coffman, Robert L, Barrat, Franck J

Volltext

IL-10 regulates plasmacytoid dendritic cell response to CpG-containing immunostimulatory sequences von Duramad, Omar, Fearon, Karen L., Chan, Jean H., Kanzler, Holger, Marshall, Jason D., Coffman, Robert L., Barrat, Franck J.

Volltext

Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions von Marshall, Jason D., Fearon, Karen, Abbate, Christi, Subramanian, Sandhya, Yee, Priscilla, Gregorio, Josh, Coffman, Robert L., Van Nest, Gary

Volltext

Superior activity of the type C class of ISS in vitro and in vivo across multiple species von Marshall, Jason D, Fearon, Karen L, Higgins, Debbie, Hessel, Edith M, Kanzler, Holger, Abbate, Christi, Yee, Priscilla, Gregorio, Josh, Cruz, Tracy Dela, Lizcano, Jennifer O, Zolotorev, Alya, McClure, Hazel M, Brasky, Kathleen M, Murthy, Krishna K, Coffman, Robert L, Nest, Gary Van

Volltext

Novel chimeric immunomodulatory compounds containing short CpG oligodeoxyribonucleotides have differential activities in human cells von Marshall, Jason D., Hessel, Edith M., Gregorio, Josh, Abbate, Christina, Yee, Priscilla, Chu, Mabel, Nest, Gary Van, Coffman, Robert L., Fearon, Karen L.

Volltext

Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays von Brenner, Sydney, Johnson, Maria, Bridgham, John, Golda, George, Lloyd, David H, Johnson, Davida, Luo, Shujun, McCurdy, Sarah, Foy, Michael, Ewan, Mark, Roth, Rithy, George, Dave, Eletr, Sam, Albrecht, Glenn, Vermaas, Eric, Williams, Steven R, Moon, Keith, Burcham, Timothy, Pallas, Michael, DuBridge, Robert B, Kirchner, James, Fearon, Karen, Mao, Jen-i, Corcoran, Kevin

Volltext

N3‘→P5‘ Oligodeoxyribonucleotide Phosphoramidates:  A New Method of Synthesis Based on a Phosphoramidite Amine-Exchange Reaction von Nelson, Jeffrey S, Fearon, Karen L, Nguyen, Mark Q, McCurdy, Sarah N, Frediani, Jeff E, Foy, Michael F, Hirschbein, Bernard L

Volltext

Synthesis of Oligo(Deoxyribonucleoside Phosphorodithioate)s by the Dithiaphospholane Approach von Okruszek, Andrzej, Sierzcha-la, Agnieszka, Fearon, Karen L, Stec, Wojciech J

Volltext

Polymyxin B enhances ISS-mediated immune responses across multiple species von Marshall, Jason D., Higgins, Debbie, Abbate, Christi, Yee, Priscilla, Teshima, Glen, Ott, Gary, dela Cruz, Tracy, Passmore, David, Fearon, Karen L., Tuck, Stephen, Van Nest, Gary

Volltext

Synthesis of sulfur-substituted phospholipid analogs as mechanistic probes of phospholipase A2 catalysis von Yuan, Wei, Fearon, Karen, Gelb, Michael H

Volltext

Fluoro ketone containing peptides as inhibitors of human renin von Fearon, Karen, Spaltenstein, Andreas, Hopkins, Paul B., Gelb, Michael H.

Volltext

A minimal human immunostimulatory CpG motif that potently induces IFN‐γ and IFN‐α production von Fearon, Karen, Marshall, Jason D., Abbate, Christi, Subramanian, Sandhya, Yee, Priscilla, Gregorio, Josh, Teshima, Glen, Ott, Gary, Tuck, Stephen, Van Nest, Gary, Coffman, Robert L.

Volltext

IMMUNOSTIMULATORY SEQUENCE OLIGONUCLEOTIDES AND METHODS OF USING THE SAME von Dina, Dino, Fearon, Karen L, Marshall, Jason

Volltext bestellen

Immunostimulatory sequence oligonucleotides and methods of using the same von Dina, Dino, Fearon, Karen L, Marshall, Jason

Volltext bestellen

IMMUNOSTIMULATORY SEQUENCE OLIGONUCLEOTIDES AND METHODS OF USING THE SAME von DINA, Dino, MARSHALL, Jason, FEARON, Karen L

Volltext bestellen

Immunostimulatory sequence oligonucleotides and methods of using the same von Dina, Dino, Fearon, Karen L, Marshall, Jason

Volltext bestellen

Bis(O,O-diisopropoxy phosphinothioyl) disulfide - a highly efficient sulfurizing reagent for cost-effective synthesis of oligo(nucleoside phosphorothioate)s von Stec, Wojciech J., Uznanski, Bogdan, Wilk, Andrzej, Hirschbein, Bernard L., Fearon, Karen L., Bergot, B.John

Volltext

Human toll-like receptor inhibitors and methods of use thereof von Guiducci Cristiana, Barrat Franck, Fearon Karen L

Volltext bestellen

HUMAN TOLL-LIKE RECEPTOR INHIBITORS AND METHODS OF USE THEREOF von GUIDUCCI, Cristiana, FEARON, Karen, L, BARRAT, Franck

Volltext bestellen

Investigation of the ‘n–1’ impurity in phosphorothioate oligodeoxynucleotides synthesized by the solid-phase β-cyanoethyl phosphoramidite method using stepwise sulfurization von Fearon, Karen L., Stults, John T., Bergot, B.John, Christensen, Laura M., Raible, Annette M.

Volltext