1392 EVOLVE-104, a novel ULBP2-targeted T cell engager that integrates CD2 costimulation for the treatment of basal and squamous lineage tumors von Tam, Eric M, Sarkar, Mohosin, Jin, Guixian, Sergeeva, Oksana A, Abulizi, Abudukadier, Lai, Zengzu, Karp, Hayden, Rodriguez, Julio, Hackett, Maria, Martomo, Stella, Dhindwal, Sonali, Teran, Evelyn, Klaskin, Danielle, Lichter, Tracy, Zeiger, Jennifer, Fearnley, Amber, Yuan, Changqing, An, Xingyue, Matis, Louis, Fine, Jay S, Myers, Jeremy S

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1386 EVOLVE-106, a T cell engager with integrated CD2 costimulation targeting B7-H4, is a precision therapy for estrogen and Her2 receptor low breast cancers von Sergeeva, Oksana A, Fearnley, Amber, Zeiger, Jennifer, Tam, Eric M, Sarkar, Mohosin, Lai, Zengzu, Jin, Guixian, Dhindwal, Sonali, Teran, Evelyn, Abulizi, Abudukadier, Sabrin, Afsana, Karp, Hayden, Rodriguez, Julio, Klaskin, Danielle, Lichter, Tracy, Metzler, Kristen, Joinville, Kyla, Martomo, Stella, Matis, Louis, Fine, Jay S, Myers, Jeremy Sh

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Population origin and heritable effects mediate road salt toxicity and thermal stress in an amphibian von Conner, Lauren M., Goedert, Debora, Fitzpatrick, Sarah W., Fearnley, Amber, Gallagher, Emma L., Peterman, Jessica D., Forgione, Mia E., Kokosinska, Sophia, Hamilton, Malik, Masala, Lydia A., Merola, Neil, Rico, Hennesy, Samma, Eman, Brady, Steven P.

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Abstract B44: EVOLVE: A novel costimulatory T cell engager platform engineered for the treatment of solid tumors von Chin, Mandy Shu Shien, Sarkar, Mohosin, Tam, Eric, Abulizi, Abudukadier, Jin, Guixian, An, Xingyue, Teran, Evelyn, Klaskin, Danielle M, Pels, Nana Adjoa, Hackett, Maria, Sergeeva, Oksana A, Karp, Hayden, Rodriguez, Julio, Dhindwal, Sonali, Yuan, Changqing, Lai, Zengzu, Zeiger, Jennifer, Fearnley, Amber, Matis, Louis, Fine, Jay, Myers, Jeremy S

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Abstract 4094: Enhanced CRISPR-Cas9 edited CAR-T cells through simultaneous inactivation of multiple T cell exhaustion pathways von Sergeeva, Oksana, Fearnley, Amber, Chin, Shu Shien, An, Xingyue, Pels, Nana Adjoa, Metzler, Kristen, Joinville, Kyla, Calderon, Lizet Aquino, Abulizi, Abudukadier, Karp, Hayden, Rodriguez, Julio, Matis, Louis, Fine, Jay, Myers, Jeremy

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Abstract 2971: EVOLVETM: A novel T cell engager platform with integrated CD2 costimulation engineered for the treatment of immune suppressive tumors von Sarkar, Mohosin, Tam, Eric M., Jin, Guixian, Chin, Shu Shien, Abulizi, Abudukadier, Sergeeva, Oksana A., Lai, Zengzu, Teran, Evelyn, Karp, Hayden, Klaskin, Danielle, Pels, Nana Adjoa, An, Xingyue, Ziegler, Jennifer, Yuan, Changqing, Hackettt, Maria, Dhindwal, Sonali, Fearnley, Amber, Rodriguez, Julio, Matis, Louis, Fine, Jay S., Myers, Jeremy S.

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1060 EVOLVETM: a novel costimulatory T cell engager platform engineered for the treatment of immune suppressive tumors von Myers, Jeremy, Sarkar, Mohosin, Abulizi, Abudukadier, Tam, Eric, Jin, Guixian, An, Xingyue, Teran, Evelyn, Chin, Shu Shien, Klaskin, Danielle, Pels, Nana Adjoa, Hackett, Maria, Sergeeva, Oksana, Karp, Hayden, Rodriguez, Julio, Dhindwal, Sonali, Yuan, Changqing, Lai, Zengzu, Zeiger, Jennifer, Fearnley, Amber, Matis, Louis, Fine, Jay

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