Caspases as therapeutic targets von Howley, B., Fearnhead, H.O.

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TPCK targets elements of mitotic spindle and induces cell cycle arrest in prometaphase von Fabian, Z., Fearnhead, H.O.

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Small molecule inhibitors of Apaf-1-related caspase- 3/-9 activation that control mitochondrial-dependent apoptosis von Malet, G, Martín, A G, Orzáez, M, Vicent, M J, Masip, I, Sanclimens, G, Ferrer-Montiel, A, Mingarro, I, Messeguer, A, Fearnhead, H O, Pérez-Payá, E

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Selective repression of the oncogene cyclin D1 by the tumor suppressor miR-206 in cancers von Elliman, S J, Howley, B V, Mehta, D S, Fearnhead, H O, Kemp, D M, Barkley, L R

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TPCK-induced apoptosis and labelling of the largest subunit of RNA polymerase II in Jurkat cells von Fabian, Z, O'Brien, P, Pajęcka, K, Fearnhead, H. O

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Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9 von Noori, Ali-Reza, Tashakor, Amin, Nikkhah, Maryam, Eriksson, Leif A., Hosseinkhani, Saman, Fearnhead, Howard O.

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Molecular Cloning of ILP-2, a Novel Member of the Inhibitor of Apoptosis Protein Family von Richter, Bettina W. M., Mir, Samy S., Eiben, Lisa J., Lewis, Jennifer, Reffey, Stephanie Birkey, Frattini, Annalisa, Tian, Lan, Frank, Stephan, Youle, Richard J., Nelson, David L., Notarangelo, Luigi D., Vezzoni, Paolo, Fearnhead, Howard O., Duckett, Colin S.

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Oncogene-Dependent Apoptosis is Mediated by Caspase-9 von Fearnhead, Howard O., Rodriguez, Joe, Govek, Eve-Ellen, Guo, Wenjun, Kobayashi, Ryuji, Hannon, Greg, Lazebnik, Yuri A.

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Assay for Ubiquitin Ligase Activity: High-Throughput Screen for Inhibitors of HDM2 von Davydov, I.V., Woods, D., Safiran, Y.J., Oberoi, P., Fearnhead, H.O., Fang, S., Jensen, J.P., Weissman, A.M., Kenten, J.H., Vousden, K.H.

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Apoptosome Formation through Disruption of the K192-D616 Salt Bridge in the Apaf‑1 Closed Form von Sahebazzamani, Fatemeh, Hosseinkhani, Saman, Eriksson, Leif A, Fearnhead, Howard O

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Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes von Cohen, GM, Sun, XM, Fearnhead, H, MacFarlane, M, Brown, DG, Snowden, RT, Dinsdale, D

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A new split‐luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation von Tashakor, Amin, H‐Dehkordi, Mahshid, O'Connell, Enda, Gomez Ganau, Sergi, Gozalbes, Rafael, Eriksson, Leif A., Hosseinkhani, Saman, Fearnhead, Howard O.

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An ICE-like protease is a common mediator of apoptosis induced by diverse stimuli in human monocytic THP.1 cells von Zhu, Huijun, Fearnhead, Howard O., Cohen, Gerald M.

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An interleukin-1β-converting enzyme-like protease is a common mediator of apoptosis in thymocytes von Fearnhead, Howard O., Dinsdale, David, Cohen, Gerald M.

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Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells von Faleiro, Lavina, Kobayashi, Ryuji, Fearnhead, Howard, Lazebnik, Yuri

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CDC2 Activation Is Not Required for Thymocyte Apoptosis von Norbury, C., Macfarlane, M., Fearnhead, H., Cohen, G.M.

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Oncogene-dependent apoptosis in extracts from drug-resistant cells von Fearnhead, H O, McCurrach, M E, O'Neill, J, Zhang, K, Lowe, S W, Lazebnik, Y A

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Dexamethasone and etoposide induce apoptosis in rat thymocytes from different phases of the cell cycle von Fearnhead, Howard O., Chwalinski, Maciej, Snowden, Roger T., Ormerod, Michael G., Cohen, Gerald M.

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DNA degradation and proteolysis in thymocyte apoptosis von Fearnhead, Howard O., MacFarlane, Marion, Dinsdale, David, Cohen, Gerald M.

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A pre-existing protease is a common effector of thymocyte apoptosis mediated by diverse stimuli von Fearnhead, Howard O., Rivett, A.Jennifer, Dinsdale, David, Cohen, Gerald M.

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