IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling von Sheng, Xia, Nenseth, Hatice Zeynep, Qu, Su, Kuzu, Omer F., Frahnow, Turid, Simon, Lukas, Greene, Stephanie, Zeng, Qingping, Fazli, Ladan, Rennie, Paul S., Mills, Ian G., Danielsen, Håvard, Theis, Fabian, Patterson, John B., Jin, Yang, Saatcioglu, Fahri

Volltext

Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer von Vandekerkhove, Gillian, Lavoie, Jean-Michel, Annala, Matti, Murtha, Andrew J., Sundahl, Nora, Walz, Simon, Sano, Takeshi, Taavitsainen, Sinja, Ritch, Elie, Fazli, Ladan, Hurtado-Coll, Antonio, Wang, Gang, Nykter, Matti, Black, Peter C., Todenhöfer, Tilman, Ost, Piet, Gibb, Ewan A., Chi, Kim N., Eigl, Bernhard J., Wyatt, Alexander W.

Volltext

ONECUT2 is a driver of neuroendocrine prostate cancer von Guo, Haiyang, Ci, Xinpei, Ahmed, Musaddeque, Hua, Junjie Tony, Soares, Fraser, Lin, Dong, Puca, Loredana, Vosoughi, Aram, Xue, Hui, Li, Estelle, Su, Peiran, Chen, Sujun, Nguyen, Tran, Liang, Yi, Zhang, Yuzhe, Xu, Xin, Xu, Jing, Sheahan, Anjali V., Ba-Alawi, Wail, Zhang, Si, Mahamud, Osman, Vellanki, Ravi N., Gleave, Martin, Bristow, Robert G., Haibe-Kains, Benjamin, Poirier, John T., Rudin, Charles M., Tsao, Ming-Sound, Wouters, Bradly G., Fazli, Ladan, Feng, Felix Y., Ellis, Leigh, van der Kwast, Theo, Berlin, Alejandro, Koritzinsky, Marianne, Boutros, Paul C., Zoubeidi, Amina, Beltran, Himisha, Wang, Yuzhuo, He, Housheng Hansen

Volltext

High fibroblast-activation-protein expression in castration-resistant prostate cancer supports the use of FAPI-molecular theranostics von Kesch, Claudia, Yirga, Leubet, Dendl, Katharina, Handke, Analena, Darr, Christopher, Krafft, Ulrich, Radtke, Jan Philipp, Tschirdewahn, Stephan, Szarvas, Tibor, Fazli, Ladan, Gleave, Martin, Giesel, Frederik L., Haberkorn, Uwe, Hadaschik, Boris

Volltext

A noncanonical AR addiction drives enzalutamide resistance in prostate cancer von He, Yundong, Wei, Ting, Ye, Zhenqing, Orme, Jacob J., Lin, Dong, Sheng, Haoyue, Fazli, Ladan, Jeffrey Karnes, R., Jimenez, Rafael, Wang, Liguo, Wang, Liewei, Gleave, Martin E., Wang, Yuzhuo, Shi, Lei, Huang, Haojie

Volltext

A PRC2-independent function for EZH2 in regulating rRNA 2′-O methylation and IRES-dependent translation von Yi, Yang, Li, Yanqiang, Meng, Qingshu, Li, Qiaqia, Li, Fuxi, Lu, Bing, Shen, Jiangchuan, Fazli, Ladan, Zhao, Dongyu, Li, Chao, Jiang, Weihua, Wang, Rui, Liu, Qipeng, Szczepanski, Aileen, Li, Qianru, Qin, Wei, Weiner, Adam B., Lotan, Tamara L., Ji, Zhe, Kalantry, Sundeep, Wang, Lu, Schaeffer, Edward M., Niu, Hengyao, Dong, Xuesen, Zhao, Wei, Chen, Kaifu, Cao, Qi

Volltext

Histone demethylase JMJD1A promotes alternative splicing of AR variant 7 (AR-V7) in prostate cancer cells von Fan, Lingling, Zhang, Fengbo, Xu, Songhui, Cui, Xiaolu, Hussain, Arif, Fazli, Ladan, Gleave, Martin, Dong, Xuesen, Qi, Jianfei

Volltext

Circulating Tumor DNA Abundance and Potential Utility in De Novo Metastatic Prostate Cancer von Vandekerkhove, Gillian, Struss, Werner J., Annala, Matti, Kallio, Heini M.L., Khalaf, Daniel, Warner, Evan W., Herberts, Cameron, Ritch, Elie, Beja, Kevin, Loktionova, Yulia, Hurtado-Coll, Antonio, Fazli, Ladan, So, Alan, Black, Peter C., Nykter, Matti, Tammela, Teuvo, Chi, Kim N., Gleave, Martin E., Wyatt, Alexander W.

Volltext

Selective targeting of PARP-2 inhibits androgen receptor signaling and prostate cancer growth through disruption of FOXA1 function von Gui, Bin, Gui, Fu, Takai, Tomoaki, Feng, Chao, Bai, Xiao, Fazli, Ladan, Dong, Xuesen, Liu, Shuai, Zhang, Xiaofeng, Zhang, Wei, Kibel, Adam S., Jia, Li

Volltext

The Master Neural Transcription Factor BRN2 Is an Androgen Receptor-Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer von Bishop, Jennifer L, Thaper, Daksh, Vahid, Sepideh, Davies, Alastair, Ketola, Kirsi, Kuruma, Hidetoshi, Jama, Randy, Nip, Ka Mun, Angeles, Arkhjamil, Johnson, Fraser, Wyatt, Alexander W, Fazli, Ladan, Gleave, Martin E, Lin, Dong, Rubin, Mark A, Collins, Colin C, Wang, Yuzhuo, Beltran, Himisha, Zoubeidi, Amina

Volltext

Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity von Cherif, Chaïma, Nguyen, Dang Tan, Paris, Clément, Le, Thi Khanh, Sefiane, Thibaud, Carbuccia, Nadine, Finetti, Pascal, Chaffanet, Max, kaoutari, Abdessamad El, Vernerey, Julien, Fazli, Ladan, Gleave, Martin, Manai, Mohamed, Barthélémy, Philippe, Birnbaum, Daniel, Bertucci, François, Taïeb, David, Rocchi, Palma

Volltext

An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer von Davies, Alastair, Nouruzi, Shaghayegh, Ganguli, Dwaipayan, Namekawa, Takeshi, Thaper, Daksh, Linder, Simon, Karaoğlanoğlu, Fatih, Omur, Meltem E., Kim, Soojin, Kobelev, Maxim, Kumar, Sahil, Sivak, Olena, Bostock, Chiara, Bishop, Jennifer, Hoogstraat, Marlous, Talal, Amina, Stelloo, Suzan, van der Poel, Henk, Bergman, Andries M., Ahmed, Musaddeque, Fazli, Ladan, Huang, Haojie, Tilley, Wayne, Goodrich, David, Feng, Felix Y., Gleave, Martin, He, Housheng Hansen, Hach, Faraz, Zwart, Wilbert, Beltran, Himisha, Selth, Luke, Zoubeidi, Amina

Volltext

Automatic grading of prostate cancer in digitized histopathology images: Learning from multiple experts von Nir, Guy, Hor, Soheil, Karimi, Davood, Fazli, Ladan, Skinnider, Brian F., Tavassoli, Peyman, Turbin, Dmitry, Villamil, Carlos F., Wang, Gang, Wilson, R. Storey, Iczkowski, Kenneth A., Lucia, M. Scott, Black, Peter C., Abolmaesumi, Purang, Goldenberg, S. Larry, Salcudean, Septimiu E.

Volltext

Moving Towards Precision Urologic Oncology: Targeting Enzalutamide-resistant Prostate Cancer and Mutated Forms of the Androgen Receptor Using the Novel Inhibitor Darolutamide (ODM-... von Borgmann, Hendrik, Lallous, Nada, Ozistanbullu, Deniz, Beraldi, Eliana, Paul, Naman, Dalal, Kush, Fazli, Ladan, Haferkamp, Axel, Lejeune, Pascale, Cherkasov, Artem, Gleave, Martin E.

Volltext

Hsp27 Regulates Epithelial Mesenchymal Transition, Metastasis, and Circulating Tumor Cells in Prostate Cancer von SHIOTA, Masaki, BISHOP, Jennifer L, GLEAVE, Martin, ZOUBEIDI, Amina, MUN NIP, Ka, ZARDAN, Anousheh, TAKEUCHI, Ario, CORDONNIER, Thomas, BERALDI, Eliana, BAZOV, Jenny, FAZLI, Ladan, CHI, Kim

Volltext

High Fidelity Patient-Derived Xenografts for Accelerating Prostate Cancer Discovery and Drug Development von DONG LIN, WYATT, Alexander W, BELL, Robert H, ANDERSON, Shawn, HURTADO-COLL, Antonio, FAZLI, Ladan, SHARMA, Manju, BELTRAN, Himisha, RUBIN, Mark, COX, Michael, GOUT, Peter W, MORRIS, James, HUI XUE, GOLDENBERG, Larry, VOLIK, Stanislav V, GLEAVE, Martin E, COLLINS, Colin C, YUZHUO WANG, YUWEI WANG, XIN DONG, HAEGERT, Anne, WU, Rebecca, BRAHMBHATT, Sonal, FAN MO, JONG, Lina

Volltext

CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer von Tsujino, Takuya, Takai, Tomoaki, Hinohara, Kunihiko, Gui, Fu, Tsutsumi, Takeshi, Bai, Xiao, Miao, Chenkui, Feng, Chao, Gui, Bin, Sztupinszki, Zsofia, Simoneau, Antoine, Xie, Ning, Fazli, Ladan, Dong, Xuesen, Azuma, Haruhito, Choudhury, Atish D., Mouw, Kent W., Szallasi, Zoltan, Zou, Lee, Kibel, Adam S., Jia, Li

Volltext

Methylation-dependent and -independent roles of EZH2 synergize in CDCA8 activation in prostate cancer von Yi, Yang, Li, Yanqiang, Li, Chao, Wu, Longxiang, Zhao, Dongyu, Li, Fuxi, Fazli, Ladan, Wang, Rui, Wang, Long, Dong, Xuesen, Zhao, Wei, Chen, Kaifu, Cao, Qi

Volltext

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis von Massie, Charles E, Lynch, Andy, Ramos-Montoya, Antonio, Boren, Joan, Stark, Rory, Fazli, Ladan, Warren, Anne, Scott, Helen, Madhu, Basetti, Sharma, Naomi, Bon, Helene, Zecchini, Vinny, Smith, Donna-Michelle, DeNicola, Gina M, Mathews, Nik, Osborne, Michelle, Hadfield, James, MacArthur, Stewart, Adryan, Boris, Lyons, Scott K, Brindle, Kevin M, Griffiths, John, Gleave, Martin E, Rennie, Paul S, Neal, David E, Mills, Ian G

Volltext

Identification of Hypermutation and Defective Mismatch Repair in ctDNA from Metastatic Prostate Cancer von Ritch, Elie, Fu, Simon Y. F., Herberts, Cameron, Wang, Gang, Warner, Evan W., Schonlau, Elena, Taavitsainen, Sinja, Murtha, Andrew J., Vandekerkhove, Gillian, Beja, Kevin, Loktionova, Yulia, Khalaf, Daniel, Fazli, Ladan, Kushnir, Igal, Ferrario, Cristiano, Hotte, Sebastien, Annala, Matti, Chi, Kim N., Wyatt, Alexander W.

Volltext