76 Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors von Marusiak, A.A, Edwards, Z.C, Hugo, W, Trotter, E.W, Girotti, M.R, Stephenson, N.L, Kong, X, Gartside, M.G, Fawdar, S, Hudson, A, Breitwieser, W, Hayward, N.K, Marais, R, Lo, R.S, Brognard, J

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Abstract A10: Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer von Fawdar, Shameem, Trotter, Eleanor W., Li, Yaoyong, Miller, Crispin, Brognard, John

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Druggable drivers of lung cancer von Fawdar, Shameem, Edwards, Zoe C, Brognard, John

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Abstract A2-18: The challenges of using large-scale genomics data to identify novel drivers of lung cancer von Hudson, Andrew M., Yates, Tim, Wirth, Chris, Li, Yaoyong, Trotter, Wendy, Fawdar, Shameem, Miller, Crispin, Brognard, John

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Abstract 2999: Targeted depletion of all somatically mutated genes in lung cancer cells facilitates identification of mutationally activated novel drivers of lung cancer von Fawdar, Shameem, Trotter, Eleanor W., Li, Yaoyong, Ientile, Sara, Miller, Crispin, Brognard, John

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Phytopharmaceuticals for Brain Health von Subhan, Shahnaz, Bagchi, Manashi

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Anti-Neurodegenerating Activity: Structure–Activity Relationship Analysis of Flavonoids von Preet, Gagan, Haj Hasan, Ahlam, Ramlagan, Piteesha, Fawdar, Shameem, Boulle, Fabien, Jaspars, Marcel

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Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors von Marusiak, Anna A., Edwards, Zoe C., Hugo, Willy, Trotter, Eleanor W., Girotti, Maria R., Stephenson, Natalie L., Kong, Xiangju, Gartside, Michael G., Fawdar, Shameem, Hudson, Andrew, Breitwieser, Wolfgang, Hayward, Nicholas K., Marais, Richard, Lo, Roger S., Brognard, John

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Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer von Fawdar, Shameem, Trotter, Eleanor W., Li, Yaoyong, Stephenson, Natalie L., Hanke, Franziska, Marusiak, Anna A., Edwards, Zoe C., Ientile, Sara, Waszkowycz, Bohdan, Miller, Crispin J., Brognard, John

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Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery von Hudson, Andrew M, Yates, Tim, Li, Yaoyong, Trotter, Eleanor W, Fawdar, Shameem, Chapman, Phil, Lorigan, Paul, Biankin, Andrew, Miller, Crispin J, Brognard, John

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Protein Kinase Cδ Deficiency Causes Mendelian Systemic Lupus Erythematosus With B Cell‐Defective Apoptosis and Hyperproliferation von Belot, Alexandre, Kasher, Paul R., Trotter, Eleanor W., Foray, Anne‐Perrine, Debaud, Anne‐Laure, Rice, Gillian I., Szynkiewicz, Marcin, Zabot, Marie‐Therese, Rouvet, Isabelle, Bhaskar, Sanjeev S., Daly, Sarah B., Dickerson, Jonathan E., Mayer, Josephine, O'Sullivan, James, Juillard, Laurent, Urquhart, Jill E., Fawdar, Shameem, Marusiak, Anna A., Stephenson, Natalie, Waszkowycz, Bohdan, Beresford, Michael W., Biesecker, Leslie G., Black, Graeme C. M., René, Céline, Eliaou, Jean‐François, Fabien, Nicole, Ranchin, Bruno, Cochat, Pierre, Gaffney, Patrick M., Rozenberg, Flore, Lebon, Pierre, Malcus, Christophe, Crow, Yanick J., Brognard, John, Bonnefoy, Nathalie

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Using large-scale genomics data to identify driver mutations in lung cancer: methods and challenges von Hudson, Andrew M, Wirth, Christopher, Stephenson, Natalie L, Fawdar, Shameem, Brognard, John, Miller, Crispin J

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Punica granatum L. mesocarp suppresses advanced glycation end products (AGEs)- and H2O2-induced oxidative stress and pro-inflammatory biomarkers von Ramlagan, Piteesha, Rondeau, Philippe, Planesse, Cynthia, Neergheen-Bhujun, Vidushi S., Fawdar, Shameem, Bourdon, Emmanuel, Bahorun, Theeshan

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Protein Kinase C[delta] Deficiency Causes Mendelian Systemic Lupus Erythematosus With B Cell-Defective Apoptosis and Hyperproliferation von Belot, Alexandre, Kasher, Paul R, Trotter, Eleanor W, ay, Anne-Perrine, Debaud, Anne-Laure, Rice, Gillian I, Szynkiewicz, Marcin, Zabot, Marie-Therese, Rouvet, Isabelle, Bhaskar, Sanjeev S, Daly, Sarah B, Dickerson, Jonathan E, Mayer, Josephine, O'Sullivan, James, Juillard, Laurent, Urquhart, Jill E, Fawdar, Shameem, Marusiak, Anna A, Stephenson, Natalie, Waszkowycz, Bohdan, W. Beresford, Michael, Biesecker, Leslie G, C. M. Black, Graeme, René, Céline, Eliaou, Jean-François, Fabien, Nicole, Ranchin, Bruno, Cochat, Pierre, Gaffney, Patrick M, Rozenberg, Flore, Lebon, Pierre, Malcus, Christophe, Crow, Yanick J, Brognard, John, Bonnefoy, Nathalie

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Punica granatum L. mesocarp suppresses advanced glycation end products (AGEs)- and H 2 O 2 -induced oxidative stress and pro-inflammatory biomarkers von Ramlagan, Piteesha, Rondeau, Philippe, Planesse, Cynthia, Neergheen-Bhujun, Vidushi S., Fawdar, Shameem, Bourdon, Emmanuel, Bahorun, Theeshan

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Deconstructing the Mechanisms of Bioactives from Food Plants in the Management of Alzheimer’s Disease von Ruhomally, Zaina Bibi, Fawdar, Shameem, Neergheen-Bhujun, Vidushi Shradha, Bahorun, Theeshan

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The neglected element of hand hygiene - significance of hand drying, efficiency of different methods and clinical implication: A review von Gammon, John, Hunt, Julian

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MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road von Caunt, Christopher J., Sale, Matthew J., Smith, Paul D., Cook, Simon J.

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Promoter methylation-regulated miR-148a-3p inhibits lung adenocarcinoma (LUAD) progression by targeting MAP3K9 von Liang, Lu, Xu, Wen-yan, Shen, Ao, Cen, Hui-yu, Chen, Zhi-jun, Tan, Lin, Zhang, Ling-min, Zhang, Yu, Fu, Ji-jun, Qin, Ai-ping, Lei, Xue-ping, Li, Song-pei, Qin, Yu-yan, Huang, Jiong-hua, Yu, Xi-yong

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The Hygienic Efficacy of Different Hand-Drying Methods: A Review of the Evidence von Huang, Cunrui, MMed, MSPH, Ma, Wenjun, MD, MPH, Stack, Susan, BBus

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