Biosensor reveals multiple sources for mitochondrial NAD von Cambronne, Xiaolu A., Stewart, Melissa L., Kim, DongHo, Jones-Brunette, Amber M., Morgan, Rory K., Farrens, David L., Cohen, Michael S., Goodman, Richard H.

Volltext

Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex von Krishna Kumar, Kaavya, Shalev-Benami, Moran, Robertson, Michael J., Hu, Hongli, Banister, Samuel D., Hollingsworth, Scott A., Latorraca, Naomi R., Kato, Hideaki E., Hilger, Daniel, Maeda, Shoji, Weis, William I., Farrens, David L., Dror, Ron O., Malhotra, Sanjay V., Kobilka, Brian K., Skiniotis, Georgios

Volltext

Structural dynamics and energetics underlying allosteric inactivation of the cannabinoid receptor CB1 von Fay, Jonathan F, Farrens, David L

Volltext

A Constitutively Activating Mutation Alters the Dynamics and Energetics of a Key Conformational Change in a Ligand-free G Protein-coupled Receptor von Tsukamoto, Hisao, Farrens, David L.

Volltext

Distance Mapping in Proteins Using Fluorescence Spectroscopy: Tyrosine, like Tryptophan, Quenches Bimane Fluorescence in a Distance-Dependent Manner von Jones Brunette, Amber M, Farrens, David L

Volltext

Decay of an active GPCR: Conformational dynamics govern agonist rebinding and persistence of an active, yet empty, receptor state von Schafer, Christopher T., Fay, Jonathan F., Janz, Jay M., Farrens, David L.

Volltext

The Membrane Proximal Region of the Cannabinoid Receptor CB1 N‑Terminus Can Allosterically Modulate Ligand Affinity von Fay, Jonathan F, Farrens, David L

Volltext

Conformational Selection and Equilibrium Governs the Ability of Retinals to Bind Opsin von Schafer, Christopher T., Farrens, David L.

Volltext

Distance Mapping in Proteins Using Fluorescence Spectroscopy: The Tryptophan-Induced Quenching (TrIQ) Method von Mansoor, Steven E, DeWitt, Mark A, Farrens, David L

Volltext

Monomeric Rhodopsin Is the Minimal Functional Unit Required for Arrestin Binding von Tsukamoto, Hisao, Sinha, Abhinav, DeWitt, Mark, Farrens, David L.

Volltext

Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry von Arttamangkul, Seksiri, Plazek, Andrew, Platt, Emily J, Jin, Haihong, Murray, Thomas F, Birdsong, William T, Rice, Kenner C, Farrens, David L, Williams, John T

Volltext

Purification of Functional CB1 and Analysis by Site-Directed Fluorescence Labeling Methods von Fay, Jonathan F, Farrens, David L

Volltext

Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes von Mathiasen, Signe, Christensen, Sune M, Fung, Juan José, Rasmussen, Søren G F, Fay, Jonathan F, Jorgensen, Sune K, Veshaguri, Salome, Farrens, David L, Kiskowski, Maria, Kobilka, Brian, Stamou, Dimitrios

Volltext

Retinal Attachment Instability Is Diversified among Mammalian Melanopsins von Tsukamoto, Hisao, Kubo, Yoshihiro, Farrens, David L., Koyanagi, Mitsumasa, Terakita, Akihisa, Furutani, Yuji

Volltext

What site-directed labeling studies tell us about the mechanism of rhodopsin activation and G-protein binding von Farrens, David L

Volltext

Fluorescence spectroscopy of rhodopsins: Insights and approaches von Alexiev, Ulrike, Farrens, David L.

Volltext

The Magnitude of the Light-induced Conformational Change in Different Rhodopsins Correlates with Their Ability to Activate G Proteins von Tsukamoto, Hisao, Farrens, David L., Koyanagi, Mitsumasa, Terakita, Akihisa

Volltext

A rapid, tag-free way to purify functional GPCRs von Shumate, Anthony D, Farrens, David L

Volltext

Requirement of Rigid-Body Motion of Transmembrane Helices for Light Activation of Rhodopsin von Farrens, David L., Altenbach, Christian, Yang, Ke, Hubbell, Wayne L., Khorana, H. Gobind

Volltext

Rhodopsin Self-Associates in Asolectin Liposomes von Mansoor, Steven E., Palczewski, Krzysztof, Farrens, David L.

Volltext