Protein Kinase C Isoforms ζ and ι Mediate Collagenase Expression and Cartilage Destruction via STAT3- and ERK-dependent c-fos Induction von Litherland, Gary J., Elias, Martina S., Hui, Wang, Macdonald, Christopher D., Catterall, Jonathon B., Barter, Matt J., Farren, Matthew J., Jefferson, Matthew, Rowan, Andrew D.

Volltext

Protein Kinase C Isoforms I and I[sup1 Mediate Collagenase Expression and Cartilage Destruction via STAT3- and ERK-dependent c-fos Induction von Litherland, Gary J, Elias, Martina S, Hui, Wang, Macdonald, Christopher D, Catterall, Jonathon B, Barter, Matt J, Farren, Matthew J, Jefferson, Matthew, Rowan, Andrew D

Volltext

The Genome Project–Write von Boeke, Jef D., Church, George, Hessel, Andrew, Kelley, Nancy J., Arkin, Adam, Cai, Yizhi, Carlson, Rob, Chakravarti, Aravinda, Cornish, Virginia W., Holt, Liam, Isaacs, Farren J., Kuiken, Todd, Lajoie, Marc, Lessor, Tracy, Lunshof, Jeantine, Maurano, Matthew T., Mitchell, Leslie A., Rine, Jasper, Rosser, Susan, Sanjana, Neville E., Silver, Pamela A., Valle, David, Wang, Harris, Way, Jeffrey C., Yang, Luhan

Volltext

Robust production of recombinant phosphoproteins using cell-free protein synthesis von Oza, Javin P., Aerni, Hans R., Pirman, Natasha L., Barber, Karl W., ter Haar, Charlotte M., Rogulina, Svetlana, Amrofell, Matthew B., Isaacs, Farren J., Rinehart, Jesse, Jewett, Michael C.

Volltext

Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor von Ye, Qinda, Shvartsbart, Artem, Li, Zhenwu, Gan, Pei, Policarpo, Rocco L, Qi, Chao, Roach, Jeremy J, Zhu, Wenyu, McCammant, Matthew S, Hu, Bin, Li, Gencheng, Yin, Haolin, Carlsen, Peter, Hoang, Gia, Zhao, Le, Susick, Robert, Zhang, Fenglei, Lai, Cheng-Tsung, Allali Hassani, Abdellah, Epling, Leslie B, Gallion, Alexandra, Kurzeja-Lipinski, Kerri, Gallagher, Karen, Roman, Valerie, Farren, Matthew R, Kong, Weixi, Deller, Marc C, Zhang, Guofeng, Covington, Maryanne, Diamond, Sharon, Kim, Sunkyu, Yao, Wenqing, Sokolsky, Alexander, Wang, Xiaozhao

Volltext

A multi-center, single-arm, phase Ib study of pembrolizumab (MK-3475) in combination with chemotherapy for patients with advanced colorectal cancer: HCRN GI14-186 von Herting, Cameron J., Farren, Matthew R., Tong, Yan, Liu, Ziyue, O’Neil, Bert, Bekaii-Saab, Tanios, Noonan, Anne, McQuinn, Christopher, Mace, Thomas A., Shaib, Walid, Wu, Christina, El-Rayes, Bassel F., Shahda, Safi, Lesinski, Gregory B.

Volltext

Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell- and CXCR3-dependent manner von Ware, Michael Brandon, Phillips, Maggie, McQuinn, Christopher, Zaidi, Mohammad Y, Knochelmann, Hannah M, Greene, Emily, Robinson, Brian, Herting, Cameron J, Mace, Thomas A, Chen, Zhengjia, Zhang, Chao, Farren, Matthew R, Ruggieri, Amanda N, Bowers, Jacob S, Shakya, Reena, Farris, Alton B, Young, Gregory, Carson, 3rd, William E, El-Rayes, Bassel, Paulos, Chrystal M, Lesinski, Gregory B

Volltext

Confronting risks of mirror life von Adamala, Katarzyna P, Agashe, Deepa, Belkaid, Yasmine, Bittencourt, Daniela Matias de C, Cai, Yizhi, Chang, Matthew W, Chen, Irene A, Church, George M, Cooper, Vaughn S, Davis, Mark M, Devaraj, Neal K, Endy, Drew, Esvelt, Kevin M, Glass, John I, Hand, Timothy W, Inglesby, Thomas V, Isaacs, Farren J, James, Wilmot G, Jones, Jonathan D G, Kay, Michael S, Lenski, Richard E, Liu, Chenli, Medzhitov, Ruslan, Nicotra, Matthew L, Oehm, Sebastian B, Pannu, Jaspreet, Relman, David A, Schwille, Petra, Smith, James A, Suga, Hiroaki, Szostak, Jack W, Talbot, Nicholas J, Tiedje, James M, Venter, J Craig, Winter, Gregory, Zhang, Weiwen, Zhu, Xinguang, Zuber, Maria T

Volltext

Evaluation of Antibacterial Functionalized Dihydropyrimidine Photoaffinity Probes Toward Mechanism of Action Studies von Russo, Christopher M., Boyer, Zachary W., Scheunemann, Kaitlyn, Farren, Jonathan, Minich, Alexandra, Wenthur, Cody J., O’Reilly, Matthew C.

Volltext

Stressful presentations: mild cold stress in laboratory mice influences phenotype of dendritic cells in naïve and tumor-bearing mice von Kokolus, Kathleen M, Spangler, Haley M, Povinelli, Benjamin J, Farren, Matthew R, Lee, Kelvin P, Repasky, Elizabeth A

Volltext

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis von Madireddy, Lohith, Patsopoulos, Nikolaos A., Cotsapas, Chris, Bos, Steffan D., Beecham, Ashley, McCauley, Jacob, Kim, Kicheol, Jia, Xiaoming, Santaniello, Adam, Caillier, Stacy J., Andlauer, Till F. M., Barcellos, Lisa F., Berge, Tone, Bernardinelli, Luisa, Martinelli-Boneschi, Filippo, Booth, David R., Briggs, Farren, Celius, Elisabeth G., Comabella, Manuel, Comi, Giancarlo, Cree, Bruce A. C., D’Alfonso, Sandra, Dedham, Katrina, Duquette, Pierre, Dardiotis, Efthimios, Esposito, Federica, Fontaine, Bertrand, Gasperi, Christiane, Goris, An, Dubois, Bénédicte, Gourraud, Pierre-Antoine, Hadjigeorgiou, Georgios, Haines, Jonathan, Hawkins, Clive, Hemmer, Bernhard, Hintzen, Rogier, Horakova, Dana, Isobe, Noriko, Kalra, Seema, Kira, Jun-ichi, Khalil, Michael, Kockum, Ingrid, Lill, Christina M., Lincoln, Matthew R., Luessi, Felix, Martin, Roland, Oturai, Annette, Palotie, Aarno, Pericak-Vance, Margaret A., Henry, Roland, Saarela, Janna, Ivinson, Adrian, Olsson, Tomas, Taylor, Bruce V., Stewart, Graeme J., Harbo, Hanne F., Compston, Alastair, Hauser, Stephen L., Hafler, David A., Zipp, Frauke, De Jager, Philip, Sawcer, Stephen, Oksenberg, Jorge R., Baranzini, Sergio E.

Volltext

A Pilot Study of a Collaborative Palliative and Oncology Care Intervention for Patients with Head and Neck Cancer von Bauman, Jessica R, Panick, Jessie R, Galloway, Thomas J, Ridge, John A, Chwistek, Marcin A, Collins, Molly E, Kinczewski, Leigh, Murphy, Kathleen, Welsh, Marie, Farren, Matthew A, Clark Omilak, Mollie, Kelly, Jacqueline, Schuster, Katherine A, Lucas, Lauren A, Amrhein, Sheila, Bender, Florence P, Temel, Jennifer S, Egleston, Brian L, El-Jawahri, Areej, Fang, Carolyn Y

Volltext

The Atacama Cosmology Telescope: Two-Season ACTPol Extragalactic Point Sources and Their Polarization Properties von Datta, Rahul, Aiola, Simone, Choi, Steve K, Devlin, Mark, Dunkley, Joanna, Dünner, Rolando, Gallardo, Patricio A, Gralla, Megan, Halpern, Mark, Hasselfield, Matthew, Hilton, Matt, Hincks, Adam D., Ho, Shuay-Pwu P, Hubmayr, Johannes, Huffenberger, Kevin M, Hughes, John P, Kosowsky, Arthur, López-Caraballo, Carlos H, Louis, Thibaut, Lungu, Marius, Marriage, Tobias, Maurin, Loïc, McMahon, Jeff, Moodley, Kavilan, Naess, Sigurd K, Nati, Federico, Niemack, Michael D, Page, Lyman, Partridge, Bruce, Prince, Heather, Staggs, Suzanne T, Switzer, Eric R, Wollack, Edward J, Farren, Gerrit

Volltext

RNA-Seq Differentiates Tumour and Host mRNA Expression Changes Induced by Treatment of Human Tumour Xenografts with the VEGFR Tyrosine Kinase Inhibitor Cediranib von Bradford, James R, Farren, Matthew, Powell, Steve J, Runswick, Sarah, Weston, Susie L, Brown, Helen, Delpuech, Oona, Wappett, Mark, Smith, Neil R, Carr, T Hedley, Dry, Jonathan R, Gibson, Neil J, Barry, Simon T

Volltext

Leptin, BMI, and a Metabolic Gene Expression Signature Associated with Clinical Outcome to VEGF Inhibition in Colorectal Cancer von Pommier, Aurélien J.C., Farren, Matthew, Patel, Bhavika, Wappett, Mark, Michopoulos, Filippos, Smith, Neil R., Kendrew, Jane, Frith, Jeremy, Huby, Russell, Eberlein, Catherine, Campbell, Hayley, Womack, Christopher, Smith, Paul D., Robertson, Jane, Morgan, Shethah, Critchlow, Susan E., Barry, Simon T.

Volltext

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis (vol 10, 2236, 2019) von Madireddy, L, Patsopoulos, NA, Cotsapas, C, Bos, SD, Beecham, A, McCauley, J, Kim, K, Jia, X, Santaniello, A, Caillier, SJ

Volltext

Author Correction: A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis von Madireddy, Lohith, Patsopoulos, Nikolaos A., Cotsapas, Chris, Bos, Steffan D., Beecham, Ashley, McCauley, Jacob, Kim, Kicheol, Jia, Xiaoming, Santaniello, Adam, Caillier, Stacy J., Andlauer, Till F. M., Barcellos, Lisa F., Berge, Tone, Bernardinelli, Luisa, Martinelli-Boneschi, Filippo, Booth, David R., Briggs, Farren, Celius, Elisabeth G., Comabella, Manuel, Comi, Giancarlo, Cree, Bruce A. C., D’Alfonso, Sandra, Dedham, Katrina, Duquette, Pierre, Dardiotis, Efthimios, Esposito, Federica, Fontaine, Bertrand, Gasperi, Christiane, Goris, An, Dubois, Bénédicte, Gourraud, Pierre-Antoine, Hadjigeorgiou, Georgios, Haines, Jonathan, Hawkins, Clive, Hemmer, Bernhard, Hintzen, Rogier, Horakova, Dana, Isobe, Noriko, Kalra, Seema, Kira, Jun-ichi, Khalil, Michael, Kockum, Ingrid, Lill, Christina M., Lincoln, Matthew R., Luessi, Felix, Martin, Roland, Oturai, Annette, Palotie, Aarno, Pericak-Vance, Margaret A., Henry, Roland, Saarela, Janna, Ivinson, Adrian, Olsson, Tomas, Taylor, Bruce V., Stewart, Graeme J., Harbo, Hanne F., Compston, Alastair, Hauser, Stephen L., Hafler, David A., Zipp, Frauke, De Jager, Philip, Sawcer, Stephen, Oksenberg, Jorge R., Baranzini, Sergio E.

Volltext

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis von Madireddy, Lohith, Patsopoulos, Niklaos A, Cotsapas, Chris, Bos, Steffan D, Beecham, Ashley, McCauley, Jacob, Kim, Kicheol, Jia, Xiaoming, Santaniello, Adam, Caillier, Stacy J, Andlauer, Till F.M, Barcellos, Lisa F, Berge, Tone, Bernardinelli, Luisa, Martinelli-Boneschi, Filippo, Booth, David R, Briggs, Farren, Celius, Elisabeth G, Comabella, Manuel, Comi, Giancarlo, Cree, Bruce A.C, D'Alfonso, Sandra, Dedham, Katrina, Duquette, Pierre, Efthimios, Dardiotis, Esposito, Federica, Fontaine, Bertrand, Gasperi, Christiane, Goris, An, Dubois, Benedicte, Gourraud, Pierre-Antoine, Hadjigeorgiou, Georgios, Haines, Jonathan, Hawkins, Clive, Hemmer, Bernhard, Hintzen, Rogier, Horakova, Dana, Isobe, Noriko, Kalra, Seema, Kira, Jun-ichi, Khalil, Michael, Kockum, Ingrid, Lill, Christina M, Lincoln, Matthew R, Luessi, Felix, Martin, Roland, Oturai, Annette, Palotie, Aarno, Pericak-Vance, Margaret A, Henry, Roland, Saarela, Janna, Ivinson, Adrian, Olsson, Tomas, Taylor, Bruce V, Stewart, Graeme J, Harbo, Hanne F, Compston, Alastair, Hauser, Stephen L, Hafler, David A, Zipp, Frauke, De Jager, Philip, Sawcer, Stephen, Oksenberg, Jorge R, Baranzini, Sergio E

Volltext

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis von Madireddy, Lohith, Patsopoulos, Nikolaos A., Cotsapas, Chris, Bos, Steffan Daniel, Beecham, Ashley, McCauley, Jacob, Kim, Kicheol, Jia, Xiaoming, Santaniello, Adam, Caillier, Stacy J., Andlauer, Till F.M., Barcellos, Lisa F., Berge, Tone, Bernardinelli, Luisa, Martinelli-Boneschi, Filippo, Booth, David R., Briggs, Farren, Celius, Elisabeth Gulowsen, Comabella, Manuel, Comi, Giancarlo, Cree, Bruce A.C., D'Alfonso, Sandra, Dedham, Katrina, Duquette, Pierre, Efthimios, Dardiotis, Esposito, Federica, Fontaine, Bertrand, Gasperi, Christiane, Goris, An, Dubois, Bénédicte, Gourraud, Pierre-Antoine, Hadjigeorgiou, Georgios, Haines, Jonathan, Hawkins, Clive, Hemmer, Bernhard, Hintzen, Rogier, Horakova, Dana, Isobe, Noriko, Kalra, Seema, Kira, Jun-ichi, Khalil, Michael, Kockum, Ingrid, Lill, Christina M., Lincoln, Matthew R, Luessi, Felix, Martin, Roland, Oturai, Annette, Palotie, Aarno, Pericak-Vance, Margaret A., Henry, Roland, Saarela, Janna, Ivinson, Adrian, Olsson, Tomas, Taylor, Bruce V., Stewart, Graeme J., Harbo, Hanne Flinstad, Compston, Alastair, Hauser, Stephen L., Hafler, David A., Zipp, Frauke, De Jager, Philip, Sawcer, Stephen, Oksenberg, Jorge R., Baranzini, Sergio E.

Volltext

Enabling equitable and affordable access to novel therapeutics for pandemic preparedness and response via creative intellectual property agreements von Griffen, Ed J, Boulet, Pascale

Volltext