Redundant Sources of Wnt Regulate Intestinal Stem Cells and Promote Formation of Paneth Cells von Farin, Henner F, Van Es, Johan H, Clevers, Hans

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Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters von Tetteh, Paul W., Basak, Onur, Farin, Henner F., Wiebrands, Kay, Kretzschmar, Kai, Begthel, Harry, van den Born, Maaike, Korving, Jeroen, de Sauvage, Frederic, van Es, Johan H., van Oudenaarden, Alexander, Clevers, Hans

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Visualization of a short-range Wnt gradient in the intestinal stem-cell niche von Farin, Henner F., Jordens, Ingrid, Mosa, Mohammed H., Basak, Onur, Korving, Jeroen, Tauriello, Daniele V. F., de Punder, Karin, Angers, Stephane, Peters, Peter J., Maurice, Madelon M., Clevers, Hans

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Strategies for genetic manipulation of adult stem cell-derived organoids von Menche, Constantin, Farin, Henner F.

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Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids von Michels, Birgitta E., Mosa, Mohammed H., Streibl, Barbara I., Zhan, Tianzuo, Menche, Constantin, Abou-El-Ardat, Khalil, Darvishi, Tahmineh, Członka, Ewelina, Wagner, Sebastian, Winter, Jan, Medyouf, Hind, Boutros, Michael, Farin, Henner F.

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Plasticity within stem cell hierarchies in mammalian epithelia von Tetteh, Paul W, Farin, Henner F, Clevers, Hans

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Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny von Yin, Xiaolei, Farin, Henner F, van Es, Johan H, Clevers, Hans, Langer, Robert, Karp, Jeffrey M

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3D model for CAR‐mediated cytotoxicity using patient‐derived colorectal cancer organoids von Schnalzger, Theresa E, de Groot, Marnix HP, Zhang, Congcong, Mosa, Mohammed H, Michels, Birgitta E, Röder, Jasmin, Darvishi, Tahmineh, Wels, Winfried S, Farin, Henner F

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A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer von Mosa, Mohammed H., Michels, Birgitta E., Menche, Constantin, Nicolas, Adele M., Darvishi, Tahmineh, Greten, Florian R., Farin, Henner F.

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Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung von Lüdtke, Timo H., Rudat, Carsten, Wojahn, Irina, Weiss, Anna-Carina, Kleppa, Marc-Jens, Kurz, Jennifer, Farin, Henner F., Moon, Anne, Christoffels, Vincent M., Kispert, Andreas

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STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis von Heichler, Christina, Scheibe, Kristina, Schmied, Anabel, Geppert, Carol I, Schmid, Benjamin, Wirtz, Stefan, Thoma, Oana-Maria, Kramer, Viktoria, Waldner, Maximilian J, Büttner, Christian, Farin, Henner F, Pešić, Marina, Knieling, Ferdinand, Merkel, Susanne, Grüneboom, Anika, Gunzer, Matthias, Grützmann, Robert, Rose-John, Stefan, Koralov, Sergei B, Kollias, George, Vieth, Michael, Hartmann, Arndt, Greten, Florian R, Neurath, Markus F, Neufert, Clemens

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Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy von Denk, Dominic, Petrocelli, Valentina, Conche, Claire, Drachsler, Moritz, Ziegler, Paul K., Braun, Angela, Kress, Alena, Nicolas, Adele M., Mohs, Kathleen, Becker, Christoph, Neurath, Markus F., Farin, Henner F., Buchholz, Christian J., Andreux, Pénélope A., Rinsch, Chris, Greten, Florian R.

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Human colon organoids reveal distinct physiologic and oncogenic Wnt responses von Michels, Birgitta E, Mosa, Mohammed H, Grebbin, Britta M, Yepes, Diego, Darvishi, Tahmineh, Hausmann, Johannes, Urlaub, Henning, Zeuzem, Stefan, Kvasnicka, Hans M, Oellerich, Thomas, Farin, Henner F

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Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b von Lüdtke, Timo H-W, Farin, Henner F, Rudat, Carsten, Schuster-Gossler, Karin, Petry, Marianne, Barnett, Phil, Christoffels, Vincent M, Kispert, Andreas

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Actin dynamics regulation by TTC7A/PI4KIIIα limits DNA damage and cell death under confinement von Gajardo, Tania, Bernard, Mathilde, Lô, Marie, Turck, Elisa, Leveau, Claire, El-Daher, Marie-Thérèse, Deslys, Alexandre, Panikulam, Patricia, Menche, Constantin, Kurowska, Mathieu, Le Lay, Gregoire, Barbier, Lucie, Moshous, Despina, Neven, Bénédicte, Farin, Henner F., Fischer, Alain, Ménasché, Gaël, de Saint Basile, Geneviève, Vargas, Pablo, Sepulveda, Fernando E.

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Controlled gene expression in primary Lgr5 organoid cultures von Koo, Bon-Kyoung, Stange, Daniel E, Sato, Toshiro, Karthaus, Wouter, Farin, Henner F, Huch, Meritxell, van Es, Johan H, Clevers, Hans

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Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ von Farin, Henner F, Karthaus, Wouter R, Kujala, Pekka, Rakhshandehroo, Maryam, Schwank, Gerald, Vries, Robert G J, Kalkhoven, Eric, Nieuwenhuis, Edward E S, Clevers, Hans

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YAP–IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis von Taniguchi, Koji, Moroishi, Toshiro, de Jong, Petrus R., Krawczyk, Michal, Grebbin, Britta Moyo, Luo, Huiyan, Xu, Rui-hua, Golob-Schwarzl, Nicole, Schweiger, Caroline, Wang, Kepeng, Di Caro, Giuseppe, Feng, Ying, Fearon, Eric R., Raz, Eyal, Kenner, Lukas, Farin, Henner F., Guan, Kun-Liang, Haybaeck, Johannes, Datz, Christian, Zhang, Kang, Karin, Michael

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AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer von Varga, Julia, Nicolas, Adele, Petrocelli, Valentina, Pesic, Marina, Mahmoud, Abdelrahman, Michels, Birgitta E., Etlioglu, Emre, Yepes, Diego, Haeupl, Bjoern, Ziegler, Paul K., Bankov, Katrin, Wild, Peter J., Wanninger, Stefan, Medyouf, Hind, Farin, Henner F., Tejpar, Sabine, Oellerich, Thomas, Ruland, Juergen, Siebel, Christian W., Greten, Florian R.

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Intestinal Inflammation and Dysregulated Immunity in Patients With Inherited Caspase-8 Deficiency von Lehle, Anna S., Farin, Henner F., Marquardt, Benjamin, Michels, Birgitta E., Magg, Thomas, Li, Yue, Liu, Yanshan, Ghalandary, Maryam, Lammens, Katja, Hollizeck, Sebastian, Rohlfs, Meino, Hauck, Fabian, Conca, Raffaele, Walz, Christoph, Weiss, Batia, Lev, Atar, Simon, Amos J., Groß, Olaf, Gaidt, Moritz M., Hornung, Veit, Clevers, Hans, Yazbeck, Nadine, Hanna-Wakim, Rima, Shouval, Dror S., Warner, Neil, Somech, Raz, Muise, Aleixo M., Snapper, Scott B., Bufler, Philip, Koletzko, Sibylle, Klein, Christoph, Kotlarz, Daniel

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