Most mammalian mRNAs are conserved targets of microRNAs von Friedman, Robin C, Farh, Kyle Kai-How, Burge, Christopher B, Bartel, David P

Volltext

Genetic and epigenetic fine mapping of causal autoimmune disease variants von Farh, Kyle Kai-How, Marson, Alexander, Zhu, Jiang, Kleinewietfeld, Markus, Housley, William J., Beik, Samantha, Shoresh, Noam, Whitton, Holly, Ryan, Russell J. H., Shishkin, Alexander A., Hatan, Meital, Carrasco-Alfonso, Marlene J., Mayer, Dita, Luckey, C. John, Patsopoulos, Nikolaos A., De Jager, Philip L., Kuchroo, Vijay K., Epstein, Charles B., Daly, Mark J., Hafler, David A., Bernstein, Bradley E.

Volltext

Genome-wide identification and characterization of functional neuronal activity–dependent enhancers von Malik, Athar N, Vierbuchen, Thomas, Hemberg, Martin, Rubin, Alex A, Ling, Emi, Couch, Cameron H, Stroud, Hume, Spiegel, Ivo, Farh, Kyle Kai-How, Harmin, David A, Greenberg, Michael E

Volltext

MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing von Grimson, Andrew, Farh, Kyle Kai-How, Johnston, Wendy K., Garrett-Engele, Philip, Lim, Lee P., Bartel, David P.

Volltext

Variation in predicted COVID‐19 risk among lemurs and lorises von Melin, Amanda D., Orkin, Joseph D., Janiak, Mareike C., Valenzuela, Alejandro, Kuderna, Lukas, Marrone, Frank, Ramangason, Hasinala, Horvath, Julie E., Roos, Christian, Kitchener, Andrew C., Khor, Chiea Chuen, Lim, Weng Khong, Lee, Jessica G. H., Tan, Patrick, Umapathy, Govindhaswamy, Raveendran, Muthuswamy, Alan Harris, R., Gut, Ivo, Gut, Marta, Lizano, Esther, Nadler, Tilo, Zinner, Dietmar, Le, Minh D., Manu, Sivakumara, Rabarivola, Clément J., Zaramody, Alphonse, Andriaholinirina, Nicole, Johnson, Steig E., Jarvis, Erich D., Fedrigo, Olivier, Wu, Dongdong, Zhang, Guojie, Farh, Kyle Kai‐How, Rogers, Jeffrey, Marques‐Bonet, Tomas, Navarro, Arcadi, Juan, David, Arora, Paramjit S., Higham, James P.

Volltext

Identification of constrained sequence elements across 239 primate genomes von Kuderna, Lukas F. K., Ulirsch, Jacob C., Rashid, Sabrina, Ameen, Mohamed, Sundaram, Laksshman, Hickey, Glenn, Cox, Anthony J., Gao, Hong, Kumar, Arvind, Aguet, Francois, Christmas, Matthew J., Clawson, Hiram, Haeussler, Maximilian, Janiak, Mareike C., Kuhlwilm, Martin, Orkin, Joseph D., Bataillon, Thomas, Manu, Shivakumara, Valenzuela, Alejandro, Bergman, Juraj, Rouselle, Marjolaine, Silva, Felipe Ennes, Agueda, Lidia, Blanc, Julie, Gut, Marta, de Vries, Dorien, Goodhead, Ian, Harris, R. Alan, Raveendran, Muthuswamy, Jensen, Axel, Chuma, Idriss S., Horvath, Julie E., Hvilsom, Christina, Juan, David, Frandsen, Peter, Schraiber, Joshua G., de Melo, Fabiano R., Bertuol, Fabrício, Byrne, Hazel, Sampaio, Iracilda, Farias, Izeni, Valsecchi, João, Messias, Malu, da Silva, Maria N. F., Trivedi, Mihir, Rossi, Rogerio, Hrbek, Tomas, Andriaholinirina, Nicole, Rabarivola, Clément J., Zaramody, Alphonse, Jolly, Clifford J., Phillips-Conroy, Jane, Wilkerson, Gregory, Abee, Christian, Simmons, Joe H., Fernandez-Duque, Eduardo, Kanthaswamy, Sree, Shiferaw, Fekadu, Wu, Dongdong, Zhou, Long, Shao, Yong, Zhang, Guojie, Keyyu, Julius D., Knauf, Sascha, Le, Minh D., Lizano, Esther, Merker, Stefan, Navarro, Arcadi, Nadler, Tilo, Khor, Chiea Chuen, Lee, Jessica, Tan, Patrick, Lim, Weng Khong, Kitchener, Andrew C., Zinner, Dietmar, Gut, Ivo, Melin, Amanda D., Guschanski, Katerina, Schierup, Mikkel Heide, Beck, Robin M. D., Karakikes, Ioannis, Wang, Kevin C., Umapathy, Govindhaswamy, Roos, Christian, Boubli, Jean P., Siepel, Adam, Kundaje, Anshul, Paten, Benedict, Lindblad-Toh, Kerstin, Rogers, Jeffrey, Marques Bonet, Tomas, Farh, Kyle Kai-How

Volltext

Clinical impact of splicing in neurodevelopmental disorders von Sanders, Stephan J, Schwartz, Grace B, Farh, Kyle Kai-How

Volltext

Predicting Splicing from Primary Sequence with Deep Learning von Jaganathan, Kishore, Kyriazopoulou Panagiotopoulou, Sofia, McRae, Jeremy F., Darbandi, Siavash Fazel, Knowles, David, Li, Yang I., Kosmicki, Jack A., Arbelaez, Juan, Cui, Wenwu, Schwartz, Grace B., Chow, Eric D., Kanterakis, Efstathios, Gao, Hong, Kia, Amirali, Batzoglou, Serafim, Sanders, Stephan J., Farh, Kyle Kai-How

Volltext

Predicting the clinical impact of human mutation with deep neural networks von Sundaram, Laksshman, Gao, Hong, Padigepati, Samskruthi Reddy, McRae, Jeremy F., Li, Yanjun, Kosmicki, Jack A., Fritzilas, Nondas, Hakenberg, Jörg, Dutta, Anindita, Shon, John, Xu, Jinbo, Batzoglou, Serafim, Li, Xiaolin, Farh, Kyle Kai-How

Volltext

Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing von Shin, Chanseok, Nam, Jin-Wu, Farh, Kyle Kai-How, Chiang, H. Rosaria, Shkumatava, Alena, Bartel, David P.

Volltext

Fine-mapping inflammatory bowel disease loci to single-variant resolution von Huang, Hailiang, Fang, Ming, Jostins, Luke, Umićević Mirkov, Maša, Boucher, Gabrielle, Anderson, Carl A., Andersen, Vibeke, Cleynen, Isabelle, Cortes, Adrian, Crins, François, D’Amato, Mauro, Deffontaine, Valérie, Dmitrieva, Julia, Docampo, Elisa, Elansary, Mahmoud, Farh, Kyle Kai-How, Franke, Andre, Gori, Ann-Stephan, Goyette, Philippe, Halfvarson, Jonas, Haritunians, Talin, Knight, Jo, Lawrance, Ian C., Lees, Charlie W., Louis, Edouard, Mariman, Rob, Meuwissen, Theo, Mni, Myriam, Momozawa, Yukihide, Parkes, Miles, Spain, Sarah L., Théâtre, Emilie, Trynka, Gosia, Satsangi, Jack, van Sommeren, Suzanne, Vermeire, Severine, Xavier, Ramnik J., Weersma, Rinse K., Duerr, Richard H., Mathew, Christopher G., Rioux, John D., McGovern, Dermot P. B., Cho, Judy H., Georges, Michel, Daly, Mark J., Barrett, Jeffrey C.

Volltext

A global catalog of whole-genome diversity from 233 primate species von Kuderna, Lukas F K, Gao, Hong, Janiak, Mareike C, Kuhlwilm, Martin, Orkin, Joseph D, Bataillon, Thomas, Manu, Shivakumara, Valenzuela, Alejandro, Bergman, Juraj, Rousselle, Marjolaine, Silva, Felipe Ennes, Agueda, Lidia, Blanc, Julie, Gut, Marta, de Vries, Dorien, Goodhead, Ian, Harris, R Alan, Raveendran, Muthuswamy, Jensen, Axel, Chuma, Idrissa S, Horvath, Julie E, Hvilsom, Christina, Juan, David, Frandsen, Peter, Schraiber, Joshua G, de Melo, Fabiano R, Bertuol, Fabrício, Byrne, Hazel, Sampaio, Iracilda, Farias, Izeni, Valsecchi, João, Messias, Malu, da Silva, Maria N F, Trivedi, Mihir, Rossi, Rogerio, Hrbek, Tomas, Andriaholinirina, Nicole, Rabarivola, Clément J, Zaramody, Alphonse, Jolly, Clifford J, Phillips-Conroy, Jane, Wilkerson, Gregory, Abee, Christian, Simmons, Joe H, Fernandez-Duque, Eduardo, Kanthaswamy, Sree, Shiferaw, Fekadu, Wu, Dongdong, Zhou, Long, Shao, Yong, Zhang, Guojie, Keyyu, Julius D, Knauf, Sascha, Le, Minh D, Lizano, Esther, Merker, Stefan, Navarro, Arcadi, Nadler, Tilo, Khor, Chiea Chuen, Lee, Jessica, Tan, Patrick, Lim, Weng Khong, Kitchener, Andrew C, Zinner, Dietmar, Gut, Ivo, Melin, Amanda D, Guschanski, Katerina, Schierup, Mikkel Heide, Beck, Robin M D, Umapathy, Govindhaswamy, Roos, Christian, Boubli, Jean P, Rogers, Jeffrey, Farh, Kyle Kai-How, Marques Bonet, Tomas

Volltext

PICS2: next-generation fine mapping via probabilistic identification of causal SNPs von Taylor, Kimberly E, Ansel, K Mark, Marson, Alexander, Criswell, Lindsey A, Farh, Kyle Kai-How

Volltext

Rare penetrant mutations confer severe risk of common diseases von Fiziev, Petko P, McRae, Jeremy, Ulirsch, Jacob C, Dron, Jacqueline S, Hamp, Tobias, Yang, Yanshen, Wainschtein, Pierrick, Ni, Zijian, Schraiber, Joshua G, Gao, Hong, Cable, Dylan, Field, Yair, Aguet, Francois, Fasnacht, Marc, Metwally, Ahmed, Rogers, Jeffrey, Marques-Bonet, Tomas, Rehm, Heidi L, O'Donnell-Luria, Anne, Khera, Amit V, Farh, Kyle Kai-How

Volltext

Phylogenomic analyses provide insights into primate evolution von Shao, Yong, Zhou, Long, Li, Fang, Zhao, Lan, Zhang, Bao-Lin, Shao, Feng, Chen, Jia-Wei, Chen, Chun-Yan, Bi, Xupeng, Zhuang, Xiao-Lin, Zhu, Hong-Liang, Hu, Jiang, Sun, Zongyi, Li, Xin, Wang, Depeng, Rivas-González, Iker, Wang, Sheng, Wang, Yun-Mei, Chen, Wu, Li, Gang, Lu, Hui-Meng, Liu, Yang, Kuderna, Lukas F K, Farh, Kyle Kai-How, Fan, Peng-Fei, Yu, Li, Li, Ming, Liu, Zhi-Jin, Tiley, George P, Yoder, Anne D, Roos, Christian, Hayakawa, Takashi, Marques-Bonet, Tomas, Rogers, Jeffrey, Stenson, Peter D, Cooper, David N, Schierup, Mikkel Heide, Yao, Yong-Gang, Zhang, Ya-Ping, Wang, Wen, Qi, Xiao-Guang, Zhang, Guojie, Wu, Dong-Dong

Volltext

Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution von Farh, Kyle Kai-How, Grimson, Andrew, Jan, Calvin, Lewis, Benjamin P, Johnston, Wendy K, Lim, Lee P, Burge, Christopher B, Bartel, David P

Volltext

Whole genomes of Amazonian uakari monkeys reveal complex connectivity and fast differentiation driven by high environmental dynamism von Hermosilla-Albala, Núria, Silva, Felipe Ennes, Cuadros-Espinoza, Sebastián, Fontsere, Claudia, Valenzuela-Seba, Alejandro, Pawar, Harvinder, Gut, Marta, Kelley, Joanna L., Ruibal-Puertas, Sandra, Alentorn-Moron, Pol, Faella, Armida, Lizano, Esther, Farias, Izeni, Hrbek, Tomas, Valsecchi, Joao, Gut, Ivo G., Rogers, Jeffrey, Farh, Kyle Kai-How, Kuderna, Lukas F. K., Marques-Bonet, Tomas, Boubli, Jean P.

Volltext

Identification of constrained sequence elements across 239 primate genomes von Kuderna, Lukas, 1989, Valenzuela, Alejandro, Navarro i Cuartiellas, Arcadi, 1969, Marquès i Bonet, Tomàs, 1975, Kai-How Farh, Kyle

Volltext

The landscape of tolerated genetic variation in humans and primates von Gao, Hong, Hamp, Tobias, Ede, Jeffrey, Schraiber, Joshua G, McRae, Jeremy, Singer-Berk, Moriel, Yang, Yanshen, Dietrich, Anastasia S D, Fiziev, Petko P, Kuderna, Lukas F K, Sundaram, Laksshman, Wu, Yibing, Adhikari, Aashish, Field, Yair, Chen, Chen, Batzoglou, Serafim, Aguet, Francois, Lemire, Gabrielle, Reimers, Rebecca, Balick, Daniel, Janiak, Mareike C, Kuhlwilm, Martin, Orkin, Joseph D, Manu, Shivakumara, Valenzuela, Alejandro, Bergman, Juraj, Rousselle, Marjolaine, Silva, Felipe Ennes, Agueda, Lidia, Blanc, Julie, Gut, Marta, de Vries, Dorien, Goodhead, Ian, Harris, R Alan, Raveendran, Muthuswamy, Jensen, Axel, Chuma, Idriss S, Horvath, Julie E, Hvilsom, Christina, Juan, David, Frandsen, Peter, de Melo, Fabiano R, Bertuol, Fabrício, Byrne, Hazel, Sampaio, Iracilda, Farias, Izeni, do Amaral, João Valsecchi, Messias, Mariluce, da Silva, Maria N F, Trivedi, Mihir, Rossi, Rogerio, Hrbek, Tomas, Andriaholinirina, Nicole, Rabarivola, Clément J, Zaramody, Alphonse, Jolly, Clifford J, Phillips-Conroy, Jane, Wilkerson, Gregory, Abee, Christian, Simmons, Joe H, Fernandez-Duque, Eduardo, Kanthaswamy, Sree, Shiferaw, Fekadu, Wu, Dongdong, Zhou, Long, Shao, Yong, Zhang, Guojie, Keyyu, Julius D, Knauf, Sascha, Le, Minh D, Lizano, Esther, Merker, Stefan, Navarro, Arcadi, Bataillon, Thomas, Nadler, Tilo, Khor, Chiea Chuen, Lee, Jessica, Tan, Patrick, Lim, Weng Khong, Kitchener, Andrew C, Zinner, Dietmar, Gut, Ivo, Melin, Amanda, Guschanski, Katerina, Schierup, Mikkel Heide, Beck, Robin M D, Umapathy, Govindhaswamy, Roos, Christian, Boubli, Jean P, Lek, Monkol, Sunyaev, Shamil, O'Donnell-Luria, Anne, Rehm, Heidi L, Xu, Jinbo, Rogers, Jeffrey, Marques-Bonet, Tomas, Farh, Kyle Kai-How

Volltext

Phylogenetic signal in primate tooth enamel proteins and its relevance for paleoproteomics von Fong-Zazueta, Ricardo, Krueger, Johanna, Alba, David M, Aymerich, Xènia, Beck, Robin M D, Cappellini, Enrico, Carrillo-Martin, Guillermo, Cirilli, Omar, Clark, Nathan, Cornejo, Omar E, Farh, Kyle Kai-How, Ferrández-Peral, Luis, Juan, David, Kelley, Joanna L, Kuderna, Lukas F K, Little, Jordan, Orkin, Joseph D, Paterson, Ryan S, Pawar, Harvinder, Marques-Bonet, Tomas, Lizano, Esther

Volltext