Metabolomic Profiling and Drug Interaction Characterization Reveal Riboflavin As a Breast Cancer Resistance Protein-Specific Endogenous Biomarker That Demonstrates Prediction of Tr... von Zhang, Yueping, Shipkova, Petia A, Warrack, Bethanne M, Nelson, David M, Wang, Linna, Huo, Runlan, Chen, Jian, Panfen, Erika, Chen, Xue-Qing, Fancher, R Marcus, Ruan, Qian, Christopher, Lisa J, Xue, Yongjun, Sinz, Michael, Shen, Hong

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Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for Organic Anion-Tr... von Gu, Xiaomei, Wang, Lifei, Gan, Jinping, Fancher, R. Marcus, Tian, Yuan, Hong, Yang, Lai, Yurong, Sinz, Michael, Shen, Hong

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Absence of OATP1B (Organic Anion–Transporting Polypeptide) Induction by Rifampin in Cynomolgus Monkeys: Determination Using the Endogenous OATP1B Marker Coproporphyrin and Tissue G... von Zhang, Yueping, Chen, Cliff, Chen, Shen-Jue, Chen, Xue-Qing, Shuster, David J., Puszczalo, Pawel D., Fancher, R. Marcus, Yang, Zheng, Sinz, Michael, Shen, Hong

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Evaluation of Rosuvastatin as an Organic Anion Transporting Polypeptide (OATP) Probe Substrate: In Vitro Transport and In Vivo Disposition in Cynomolgus Monkeys von Shen, Hong, Su, Hong, Liu, Tongtong, Yao, Ming, Mintier, Gabe, Li, Lun, Fancher, R. Marcus, Iyer, Ramaswamy, Marathe, Punit, Lai, Yurong, Rodrigues, A. David

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Evaluation of Encequidar as An Intestinal P-gp and BCRP Specific Inhibitor to Assess the Role of Intestinal P-gp and BCRP in Drug-Drug Interactions von Chu, Jessica, Panfen, Erika, Wang, Linna, Marino, Anthony, Chen, Xue-Qing, Fancher, R. Marcus, Landage, Raviraj, Patil, Omprakash, Desai, Salil Dileep, Shah, Devang, Xue, Yongjun, Sinz, Michael, Shen, Hong

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A convenient strategy to overcome interference in LC-MS/MS analysis: Application in a microdose absolute bioavailability study von Yuan, Long, Huang, Christine, Liu-Kreyche, Peggy, Voronin, Kimberly, Fancher, R. Marcus, Allentoff, Alban, Zheng, Naiyu, Iyer, Ramaswamy, Zhu, Li, Pillutla, Renuka, Ji, Qin C.

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Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation von Shen, Hong, Liu, Tongtong, Jiang, Hao, Titsch, Craig, Taylor, Kristin, Kandoussi, Hamza, Qiu, Xi, Chen, Cliff, Sukrutharaj, Sunil, Kuit, Kathy, Mintier, Gabe, Krishnamurthy, Prasad, Fancher, R. Marcus, Zeng, Jianing, Rodrigues, A. David, Marathe, Punit, Lai, Yurong

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Increasing the Reuse of Protein Non-Naïve Nonhuman Primates in Pharmaceutical Drug Discovery and Development: An Overview and Industry Position on the Challenges and Benefits von Mattis, Charles, Bratcher, Natalie, Burns, Monika, Carosino, Christopher, de Zafra, Christina, Fancher, R. Marcus, Georgi, Katrin, Graff, Candace, Hukkanen, Renee R., Johnson, Colena, Lao, Yanbin, Lange, Amber, Lee, Donna, Lepherd, Michelle, Maguire, Sean, Malisauskas, Mantas, Manuel, Melinda, Miranda, Sonia, Reed, Lori, Santos, Rosemary, Sayers, Brian, Shaw, David, Shuster, David

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Investigation of the “true” extraction recovery of analytes from multiple types of tissues and its impact on tissue bioanalysis using two model compounds von Yuan, Long, Ma, Li, Dillon, Lisa, Fancher, R. Marcus, Sun, Huadong, Zhu, Mingshe, Lehman-McKeeman, Lois, Aubry, Anne-Françoise, Ji, Qin C.

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Development of a Canine Model to Enable the Preclinical Assessment of Ph-dependent Absorption of Test Compounds von Fancher, R. Marcus, Zhang, Hongjian, Sleczka, Bogdan, Derbin, George, Rockar, Richard, Marathe, Punit

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Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement von Li, Wenying, Zhao, Weiping, Liu, Xiaohong, Huang, Xiaohua, Lopez, Omar D., Leet, John E., Fancher, R. Marcus, Nguyen, Van, Goodrich, Jason, Easter, John, Hong, Yang, Caceres-Cortes, Janet, Chang, Shu Y., Ma, Li, Belema, Makonen, Hamann, Lawrence G., Gao, Min, Zhu, Mingshe, Shu, Yue-Zhong, Humphreys, W. Griffith, Johnson, Benjamin M.

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Utility of in situ sodium alginate/karaya gum gels to facilitate gastric retention in rodents von Foster, Kimberly A., Morgen, Mike, Murri, Brice, Yates, Ian, Fancher, R. Marcus, Ehrmann, Jon, Gudmundsson, Olafur S., Hageman, Michael J.

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