ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types von Chüeh, Anderly C., Tse, Janson W.T., Dickinson, Michael, Ioannidis, Paul, Jenkins, Laura, Togel, Lars, Tan, BeeShin, Luk, Ian, Davalos-Salas, Mercedes, Nightingale, Rebecca, Thompson, Matthew R., Williams, Bryan R.G., Lessene, Guillaume, Lee, Erinna F., Fairlie, Walter D., Dhillon, Amardeep S., Mariadason, John M.

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Co-Operativity between MYC and BCL-2 Pro-Survival Proteins in Cancer von Fairlie, Walter Douglas, Lee, Erinna F

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role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins von Mérino, Delphine, Giam, Maybelline, Hughes, Peter D, Siggs, Owen M, Heger, Klaus, O'Reilly, Lorraine A, Adams, Jerry M, Strasser, Andreas, Lee, Erinna F, Fairlie, Walter D, Bouillet, Philippe

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MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib von Young, Adelaide I J, Law, Andrew M K, Castillo, Lesley, Chong, Sabrina, Cullen, Hayley D, Koehler, Martin, Herzog, Sebastian, Brummer, Tilman, Lee, Erinna F, Fairlie, Walter D, Lucas, Morghan C, Herrmann, David, Allam, Amr, Timpson, Paul, Watkins, D Neil, Millar, Ewan K A, O'Toole, Sandra A, Gallego-Ortega, David, Ormandy, Christopher J, Oakes, Samantha R

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Bcl-2, Bcl-xL, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells von Mérino, Delphine, Khaw, Seong L., Glaser, Stefan P., Anderson, Daniel J., Belmont, Lisa D., Wong, Chihunt, Yue, Peng, Robati, Mikara, Phipson, Belinda, Fairlie, Walter D., Lee, Erinna F., Campbell, Kirsteen J., Vandenberg, Cassandra J., Cory, Suzanne, Roberts, Andrew W., Ludlam, Mary J.C., Huang, David C.S., Bouillet, Philippe

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Correction: ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors Across Tumor Types von Chüeh, Anderly C., Tse, Janson W.T., Dickinson, Michael, Ioannidis, Paul, Jenkins, Laura, Togel, Lars, Tan, BeeShin, Luk, Ian, Davalos-Salas, Mercedes, Nightingale, Rebecca, Thompson, Matthew R., Williams, Bryan R.G., Lessene, Guillaume, Lee, Erinna F., Fairlie, Walter D., Dhillon, Amardeep S., Mariadason, John M.

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Induction of endoplasmic reticulum stress is associated with the anti‐tumor activity of monepantel across cancer types von Harris, Tiffany J., Liao, Yang, Shi, Wei, Evangelista, Marco, Pal, Bhupinder, Puthalakath, Hamsa, Aston, Roger, Mollard, Richard, Mariadason, John M., Lee, Erinna F., Fairlie, Walter D.

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In situ visualization of endothelial cell-derived extracellular vesicle formation in steady state and malignant conditions von Atkin-Smith, Georgia K., Santavanond, Jascinta P., Light, Amanda, Rimes, Joel S., Samson, Andre L., Er, Jeremy, Liu, Joy, Johnson, Darryl N., Le Page, Mélanie, Rajasekhar, Pradeep, Yip, Raymond K. H., Geoghegan, Niall D., Rogers, Kelly L., Chang, Catherine, Bryant, Vanessa L., Margetts, Mai, Keightley, M. Cristina, Kilpatrick, Trevor J., Binder, Michele D., Tran, Sharon, Lee, Erinna F., Fairlie, Walter D., Ozkocak, Dilara C., Wei, Andrew H., Hawkins, Edwin D., Poon, Ivan K. H.

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A novel BH3-mimetic, AZD0466, targeting BCL-XL and BCL-2 is effective in pre-clinical models of malignant pleural mesothelioma von Arulananda, Surein, O’Brien, Megan, Evangelista, Marco, Jenkins, Laura J., Poh, Ashleigh R., Walkiewicz, Marzena, Leong, Trishe, Mariadason, John M., Cebon, Jonathan, Balachander, Srividya B., Cidado, Justin R., Lee, Erinna F., John, Thomas, Fairlie, Walter D.

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Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM von Rohrbeck, Leona, Gong, Jia-Nan, Lee, Erinna F, Kueh, Andrew J, Behren, Andreas, Tai, Lin, Lessene, Guillaume, Huang, David C S, Fairlie, Walter D, Strasser, Andreas, Herold, Marco J

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Characterization of a novel human BFL-1-specific monoclonal antibody von Gangoda, Lahiru, Teh, Charis E., Dengler, Michael A., Best, Sarah A., Weeden, Clare E., Tai, Lin, Lee, Erinna F., Fairlie, Walter D., Sutherland, Kate D., Harrison, Leonard C., Gray, Daniel H., Strasser, Andreas, Herold, Marco J.

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Abstract 2492: BRAF inhibitors synergize with BH3 mimetics to induce apoptosis in BRAF mutant colorectal cancer cells von Jenkins, Laura J., Chionh, Fiona, Luk, Ian Y., Lee, Erinna F., Dhillon, Amardeep S., Tebbutt, Niall, Fairlie, Walter D., Mariadason, John M.

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Repurposing apoptosis-inducing cancer drugs to treat schistosomiasis von Lee, Erinna F, Fairlie, Walter Douglas

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ATF3 Repression of BCL-X L Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types von Chüeh, Anderly C, Tse, Janson W T, Dickinson, Michael, Ioannidis, Paul, Jenkins, Laura, Togel, Lars, Tan, BeeShin, Luk, Ian, Davalos-Salas, Mercedes, Nightingale, Rebecca, Thompson, Matthew R, Williams, Bryan R G, Lessene, Guillaume, Lee, Erinna F, Fairlie, Walter D, Dhillon, Amardeep S, Mariadason, John M

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Abstract B014: Genotype-tailored ERK/MAPK pathway and HDAC inhibition rewires the apoptotic rheostat to trigger colorectal cancer cell death von Jenkins, Laura J., Luk, Ian Y., Fairlie, Walter D., Lee, Erinna F., Palmieri, Michelle, Schoffer, Kael L., Tan, Tao, Ng, Irvin, Vukelic, Natalia, Tran, Sharon, Tse, Janson, Nightingale, Rebecca, Alam, Zakia, Chionh, Fiona, Iatropoulos, George, Ernst, Matthias, Afshar-Sterle, Shoukat, Desai, Jayesh, Gibbs, Peter, Sieber, Oliver M., Dhillon, Amardeep S., Tebbutt, Niall C., Mariadason, John M.

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The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins von Mérino, Delphine, Giam, Maybelline, Hughes, Peter D., Siggs, Owen M., Heger, Klaus, O'Reilly, Lorraine A., Adams, Jerry M., Strasser, Andreas, Lee, Erinna F., Fairlie, Walter D., Bouillet, Philippe

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STRUCTURAL BIOLOGY OF THE INTRINSIC CELL DEATH PATHWAY: WHAT DO WE KNOW AND WHAT IS MISSING? von Walter Douglas Fairlie, Erinna Faith Lee

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Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells von Mérino, Delphine, Khaw, Seong L, Glaser, Stefan P, Anderson, Daniel J, Belmont, Lisa D, Wong, Chihunt, Yue, Peng, Robati, Mikara, Phipson, Belinda, Fairlie, Walter D, Lee, Erinna F, Campbell, Kirsteen J, Vandenberg, Cassandra J, Cory, Suzanne, Roberts, Andrew W, Ludlam, Mary J C, Huang, David C S, Bouillet, Philippe

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Terapeutiske pro-apoptotiske BH-3-lignende molekyler og fremgangsmåde til at danne og/eller udvælge den samme von FAIRLIE, Walter, Douglas, LEE, Erinna, Faith, COLMAN, Peter, Malcolm, HUANG, David, Ching, Siang

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Terapeutisk pro-apoptotisk BH3-lignende molekyler og fremgangsmåder til at generere og/eller udvælge disse von Lee, Erinna Faith, HUANG, David Ching Siang, Fairlie, Walter Douglas, Colman, Peter Malcolm

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