A Buchwald–Hartwig Protocol to Enable Rapid Linker Exploration of Cereblon E3‐Ligase PROTACs von Hayhow, Thomas G., Borrows, Rachel E. A., Diène, Coura R., Fairley, Gary, Fallan, Charlene, Fillery, Shaun M., Scott, James S., Watson, David W.

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Diverse Heterocyclic Scaffolds as Allosteric Inhibitors of AKT von Kettle, Jason G, Brown, Simon, Crafter, Claire, Davies, Barry R, Dudley, Phillippa, Fairley, Gary, Faulder, Paul, Fillery, Shaun, Greenwood, Hannah, Hawkins, Janet, James, Michael, Johnson, Keith, Lane, Clare D, Pass, Martin, Pink, Jennifer H, Plant, Helen, Cosulich, Sabina C

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Pyridone Functionalization: Regioselective Deprotonation of 6-Methylpyridin-2(1H)- and -4(1H)-one Derivatives von Diaz Ropero, Beatriz P. Fernandez, Elsegood, Mark R. J., Fairley, Gary, Pritchard, Gareth J., Weaver, George W.

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One-pot synthesis of novel 1,2,6,7-tetrahydro-3H-pyrazolo[4,3-c]pyridine-3,4(5H)-diones von Fairley, Gary, Greenwood, Ryan, McMillan, Caroline Anne

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Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC... von Ward, Richard A, Anderton, Mark J, Bethel, Paul, Breed, Jason, Cook, Calum, Davies, Emma J, Dobson, Andrew, Dong, Zhiqiang, Fairley, Gary, Farrington, Paul, Feron, Lyman, Flemington, Vikki, Gibbons, Francis D, Graham, Mark A, Greenwood, Ryan, Hanson, Lyndsey, Hopcroft, Philip, Howells, Rachel, Hudson, Julian, James, Michael, Jones, Clifford D, Jones, Christopher R, Li, Yongchao, Lamont, Scott, Lewis, Richard, Lindsay, Nicola, McCabe, James, McGuire, Thomas, Rawlins, Philip, Roberts, Karen, Sandin, Linda, Simpson, Iain, Swallow, Steve, Tang, Jia, Tomkinson, Gary, Tonge, Michael, Wang, Zhenhua, Zhai, Baochang

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Small Molecule Binding Sites on the Ras:SOS Complex Can Be Exploited for Inhibition of Ras Activation von Winter, Jon J. G, Anderson, Malcolm, Blades, Kevin, Brassington, Claire, Breeze, Alexander L, Chresta, Christine, Embrey, Kevin, Fairley, Gary, Faulder, Paul, Finlay, M. Raymond V, Kettle, Jason G, Nowak, Thorsten, Overman, Ross, Patel, S. Joe, Perkins, Paula, Spadola, Loredana, Tart, Jonathan, Tucker, Julie A, Wrigley, Gail

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Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of ERK1/2 von Ward, Richard A, Colclough, Nicola, Challinor, Mairi, Debreczeni, Judit E, Eckersley, Kay, Fairley, Gary, Feron, Lyman, Flemington, Vikki, Graham, Mark A, Greenwood, Ryan, Hopcroft, Philip, Howard, Tina D, James, Michael, Jones, Clifford D, Jones, Christopher R, Renshaw, Jonathan, Roberts, Karen, Snow, Lindsay, Tonge, Michael, Yeung, Kay

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Synthesis of Novel Pyrazine-Substituted 1H-Pyrrole-2-carboxamides and Related Tethered Heterocycles von Howells, Rachel L., Lamont, Scott G., McGuire, Thomas M., Hughes, Samantha, Borrows, Rachel, Fairley, Gary, Feron, Lyman J. L., Greenwood, Ryan D. R., Lenz, Eva, Grant, Emma, Simpson, Iain

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Optimization of an Imidazo[1,2‑a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy von McCoull, William, Boyd, Scott, Brown, Martin R, Coen, Muireann, Collingwood, Olga, Davies, Nichola L, Doherty, Ann, Fairley, Gary, Goldberg, Kristin, Hardaker, Elizabeth, He, Guang, Hennessy, Edward J, Hopcroft, Philip, Hodgson, George, Jackson, Anne, Jiang, Xiefeng, Karmokar, Ankur, Lainé, Anne-Laure, Lindsay, Nicola, Mao, Yumeng, Markandu, Roshini, McMurray, Lindsay, McLean, Neville, Mooney, Lorraine, Musgrove, Helen, Nissink, J. Willem M, Pflug, Alexander, Reddy, Venkatesh Pilla, Rawlins, Philip B, Rivers, Emma, Schimpl, Marianne, Smith, Graham F, Tentarelli, Sharon, Travers, Jon, Troup, Robert I, Walton, Josephine, Wang, Cheng, Wilkinson, Stephen, Williamson, Beth, Winter-Holt, Jon, Yang, Dejian, Zheng, Yuting, Zhu, Qianxiu, Smith, Paul D

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Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point von Ward, Richard A, Bethel, Paul, Cook, Calum, Davies, Emma, Debreczeni, Judit E, Fairley, Gary, Feron, Lyman, Flemington, Vikki, Graham, Mark A, Greenwood, Ryan, Griffin, Nicola, Hanson, Lyndsey, Hopcroft, Philip, Howard, Tina D, Hudson, Julian, James, Michael, Jones, Clifford D, Jones, Christopher R, Lamont, Scott, Lewis, Richard, Lindsay, Nicola, Roberts, Karen, Simpson, Iain, St-Gallay, Steve, Swallow, Steve, Tang, Jia, Tonge, Michael, Wang, Zhenhua, Zhai, Baochang

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Isolation and structure determination of the first example of the azeto[2,3-c]quinolizinedione ring system von Fernandez, Beatriz, Elsegood, Mark R.J., Fairley, Gary, Pritchard, Gareth J., Teat, Simon J., Weaver, George W.

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Discovery and Optimization of a Novel Series of Dyrk1B Kinase Inhibitors To Explore a MEK Resistance Hypothesis von Kettle, Jason G, Ballard, Peter, Bardelle, Catherine, Cockerill, Mark, Colclough, Nicola, Critchlow, Susan E, Debreczeni, Judit, Fairley, Gary, Fillery, Shaun, Graham, Mark A, Goodwin, Louise, Guichard, Sylvie, Hudson, Kevin, Ward, Richard A, Whittaker, David

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Addition of Fluorine and a Late-Stage Functionalization (LSF) of the Oral SERD AZD9833 von Scott, James S, Moss, Thomas A, Barlaam, Bernard, Davey, Paul R. J, Fairley, Gary, Gangl, Eric T, Greenwood, Ryan D. R, Hatoum-Mokdad, Holia, Lister, Andrew S, Longmire, David, Polanski, Radoslaw, Stokes, Stephen, Tucker, Michael J, Varnes, Jeffrey G, Yang, Bin

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Novel and Versatile Synthesis of Disubstituted 1,2-Dihydro-1,2,4-triazol-3-ones von Graham, Mark A, Bethel, Paul A, Burgess, Jonathan, Fairley, Gary, Glossop, Steve C, Greenwood, Ryan D. R, Jones, Clifford D, Lovell, Scott, Swallow, Steve

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Formulation von Martin Ridge, Gary Fairley

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A contribution to the understanding of polyethylene/ionomer/polyamide-6 blends von Fairley, Gary, Prud'Homme, Robert E.

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Formulation von Martin Ridge, Gary Fairley

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The Preparation of a New “Safety Catch” Ester Linker for Solid-Phase Synthesis von Beech, Claire L, Coope, John F, Fairley, Gary, Gilbert, Philip S, Main, Brian G, Plé, Karen

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Pyridone functionalization: regioselective deprotonation of 6-methylpyridin-2(1H)- and -4(1H)-one derivatives von Beatriz Fernandez D.-R., Mark Elsegood, Gary Fairley, Gareth Pritchard, George Weaver

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Isolation and structure determination of the first example of the azeto[2,3-c]quinolizinedione ring system von Beatriz Fernandez-Diaz-Ropero, Mark Elsegood, Gary Fairley, Gareth Pritchard, Simon J. Teat, George Weaver

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