Identifying drug targets in tissues and whole blood with thermal-shift profiling von Perrin, Jessica, Werner, Thilo, Kurzawa, Nils, Rutkowska, Anna, Childs, Dorothee D., Kalxdorf, Mathias, Poeckel, Daniel, Stonehouse, Eugenia, Strohmer, Katrin, Heller, Bianca, Thomson, Douglas W., Krause, Jana, Becher, Isabelle, Eberl, H. Christian, Vappiani, Johanna, Sevin, Daniel C., Rau, Christina E., Franken, Holger, Huber, Wolfgang, Faelth-Savitski, Maria, Savitski, Mikhail M., Bantscheff, Marcus, Bergamini, Giovanna

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Ion Coalescence of Neutron Encoded TMT 10-Plex Reporter Ions von Werner, Thilo, Sweetman, Gavain, Savitski, Maria Fälth, Mathieson, Toby, Bantscheff, Marcus, Savitski, Mikhail M

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Tracking cancer drugs in living cells by thermal profiling of the proteome von Savitski, Mikhail M., Reinhard, Friedrich B. M., Franken, Holger, Werner, Thilo, Savitski, Maria Fälth, Eberhard, Dirk, Molina, Daniel Martinez, Jafari, Rozbeh, Dovega, Rebecca Bakszt, Klaeger, Susan, Kuster, Bernhard, Nordlund, Pär, Bantscheff, Marcus, Drewes, Gerard

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Thermal proteome profiling monitors ligand interactions with cellular membrane proteins von Reinhard, Friedrich B M, Eberhard, Dirk, Werner, Thilo, Franken, Holger, Childs, Dorothee, Doce, Carola, Savitski, Maria Fälth, Huber, Wolfgang, Bantscheff, Marcus, Savitski, Mikhail M, Drewes, Gerard

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Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis von Savitski, Mikhail M., Zinn, Nico, Faelth-Savitski, Maria, Poeckel, Daniel, Gade, Stephan, Becher, Isabelle, Muelbaier, Marcel, Wagner, Anne J., Strohmer, Katrin, Werner, Thilo, Melchert, Stephanie, Petretich, Massimo, Rutkowska, Anna, Vappiani, Johanna, Franken, Holger, Steidel, Michael, Sweetman, Gavain M., Gilan, Omer, Lam, Enid Y.N., Dawson, Mark A., Prinjha, Rab K., Grandi, Paola, Bergamini, Giovanna, Bantscheff, Marcus

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Catalytic in vivo protein knockdown by small-molecule PROTACs von Bondeson, Daniel P, Mares, Alina, Smith, Ian E D, Ko, Eunhwa, Campos, Sebastien, Miah, Afjal H, Mulholland, Katie E, Routly, Natasha, Buckley, Dennis L, Gustafson, Jeffrey L, Zinn, Nico, Grandi, Paola, Shimamura, Satoko, Bergamini, Giovanna, Faelth-Savitski, Maria, Bantscheff, Marcus, Cox, Carly, Gordon, Deborah A, Willard, Ryan R, Flanagan, John J, Casillas, Linda N, Votta, Bartholomew J, den Besten, Willem, Famm, Kristoffer, Kruidenier, Laurens, Carter, Paul S, Harling, John D, Churcher, Ian, Crews, Craig M

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DOT: a flexible multi-objective optimization framework for transferring features across single-cell and spatial omics von Rahimi, Arezou, Vale-Silva, Luis A., Fälth Savitski, Maria, Tanevski, Jovan, Saez-Rodriguez, Julio

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Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo von Wang, Peng, Joberty, Gerard, Buist, Arjan, Vanoosthuyse, Alexandre, Stancu, Ilie-Cosmin, Vasconcelos, Bruno, Pierrot, Nathalie, Faelth-Savitski, Maria, Kienlen-Campard, Pascal, Octave, Jean-Noël, Bantscheff, Marcus, Drewes, Gerard, Moechars, Diederik, Dewachter, Ilse

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The Commonly Used PI3-Kinase Probe LY294002 Is an Inhibitor of BET Bromodomains von Dittmann, Antje, Werner, Thilo, Chung, Chun-Wa, Savitski, Mikhail M, Fälth Savitski, Maria, Grandi, Paola, Hopf, Carsten, Lindon, Matthew, Neubauer, Gitte, Prinjha, Rabinder K, Bantscheff, Marcus, Drewes, Gerard

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Affinity Profiling of the Cellular Kinome for the Nucleotide Cofactors ATP, ADP, and GTP von Becher, Isabelle, Savitski, Mikhail M, Savitski, Maria Fälth, Hopf, Carsten, Bantscheff, Marcus, Drewes, Gerard

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Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition von Burtscher, Mira L, Gade, Stephan, Garrido-Rodriguez, Martin, Rutkowska, Anna, Werner, Thilo, Eberl, H Christian, Petretich, Massimo, Knopf, Natascha, Zirngibl, Katharina, Grandi, Paola, Bergamini, Giovanna, Bantscheff, Marcus, Fälth-Savitski, Maria, Saez-Rodriguez, Julio

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Quantifying Small Molecule-Induced Changes in Cellular Protein Expression and Posttranslational Modifications Using Isobaric Mass Tags von Becher, Isabelle, Savitski, Maria Fälth, Bantscheff, Marcus

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Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation von Rutkowska, Anna, Eberl, H Christian, Werner, Thilo, Hennrich, Marco L, Sévin, Daniel C, Petretich, Massimo, Reddington, James P, Pocha, Shirin, Gade, Stephan, Martinez-Segura, Amalia, Dvornikov, Dmytro, Karpiak, Joel, Sweetman, Gavain M A, Fufezan, Christian, Duempelfeld, Birgit, Braun, Florian, Schofield, Christopher, Keles, Hakan, Alvarado, David, Wang, Zhuo, Jansson, Keith H, Faelth-Savitski, Maria, Curry, Edward, Remlinger, Katja, Stronach, Euan A, Feng, Bin, Sharma, Geeta, Coleman, Kevin, Grandi, Paola, Bantscheff, Marcus, Bergamini, Giovanna

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Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress von Qin, Pu, Arabacilar, Pelin, Bernard, Roberta E, Bao, Weike, Olzinski, Alan R, Guo, Yuanjun, Lal, Hind, Eisennagel, Stephen H, Platchek, Michael C, Xie, Wensheng, Del Rosario, Julius, Nayal, Mohamad, Lu, Quinn, Roethke, Theresa, Schnackenberg, Christine G, Wright, Fe, Quaile, Michael P, Halsey, Wendy S, Hughes, Ashley M, Sathe, Ganesh M, Livi, George P, Kirkpatrick, Robert B, Qu, Xiaoyan A, Rajpal, Deepak K, Faelth Savitski, Maria, Bantscheff, Marcus, Joberty, Gerard, Bergamini, Giovanna, Force, Thomas L, Gatto, Jr, Gregory J, Hu, Erding, Willette, Robert N

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New Allosteric Inhibitors of Mutant IDH1 in Acute Myeloid Leukemia von Okoye-Okafor, Ujunwa Cynthia, Bartholdy, Boris, Cartier, Jessy, Gao, Enoch, Pietrak, Beth, Rendina, Alan R., Rominger, Cynthia, Quinn, Chad, Smallwood, Angela, Wiggall, Ken, Reif, Alexander, Schmidt, Stan, Qi, Hongwei, Zhao, Huizhen, Joberty, Gerard, Faelth-Savitski, Maria, Bantscheff, Marcus, Drewes, Gerard, Duraiswami, Chaya, Brady, Pat, Narayanagari, Swathi-rao, Antony-Debre, Ileana, Mitchell, Kelly, Carvajal, Luis, Wang, Heng Rui, Barreyro, Laura, Kao, Yun-Ruei, Christopeit, Maximilian, Paietta, Elisabeth, Makishima, Hideki, Will, Britta, Concha, Nestor, Adams, Nicholas, Schwartz, Benjamin, McCabe, Michael T., Maciejewski, Jaroslaw P., Verma, Amit, Steidl, Ulrich

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New IDH1 mutant inhibitors for treatment of acute myeloid leukemiaf von Okoye-oka, Ujunwa C, Bartholdy, Boris, Cartier, Jessy, Gao, Enoch N, Pietrak, Beth, Rendina, Alan R, Rominger, Cynthia, Quinn, Chad, Smallwood, Angela, Wiggall, Kenneth J, Reif, Alexander J, Schmidt, Stanley J, Qi, Hongwei, Zhao, Huizhen, Joberty, Gerard, Faelth-savitski, Maria, Bantscheff, Marcus, Drewes, Gerard, Duraiswami, Chaya, Brady, Pat, Groy, Arthur, Narayanagari, Swathi-rao, Antony-debre, Iléana, Mitchell, Kelly, Wang, Heng Rui, Kao, Yun-ruei, Christopeit, Maximilian, Carvajal, Luis, Barreyro, Laura, Paietta, Elisabeth, Makishima, Hideki, Will, Britta, Concha, Nestor, Adams, Nicholas D, Schwartz, Benjamin, Mccabe, Michael T, Maciejewski, Jaroslav, Verma, Amit, Steidl, Ulrich

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Abstract C38: Novel allosteric IDH1 mutant Inhibitors for differentiation therapy of acute myeloid leukemia von Okoye-Okafor, Ujunwa C., Bartholdy, Boris, Cartier, Jessy, Gao, Enoch, Pietrak, Beth, Rendina, Alan R., Rominger, Cynthia, Quinn, Chad, Smallwood, Angela, Wiggall, Ken, Reif, Alexander, Schmidt, Stan, Qi, Hongwei, Zhao, Huizhen, Joberty, Gerard, Faelth-Savitski, Maria, Bantscheff, Marcus, Drewes, Gerard, Duraiswami, Chaya, Brady, Pat, Narayanagari, Swathi-Rao, Antony-Debre, Ileana, Mitchell, Kelly, Wang, Heng Rui, Kao, Yun-Ruei, Christopeit, Maximilian, Carvajal, Luis, Barreyro, Laura, Paietta, Elisabeth, Will, Britta, Concha, Nestor, Adams, Nicholas D., Schwartz, Benjamin, McCabe, Michael T., Maciejewski, Jaroslav, Verma, Amit, Steidl, Ulrich

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Novel IDH1 Mutant Inhibitors for Treatment of Acute Myeloid Leukemia von Okoye-Okafor, Ujunwa C., Bartholdy, Boris, Cartier, Jessy, Gao, Enoch, Pietrak, Beth, Rendina, Alan R., Rominger, Cynthia, Quinn, Chad, Smallwood, Angela, Wiggall, Kenneth J., Reif, Alexander J., Schmidt, Stanley J., Qi, Hongwei, Zhao, Huizhen, Joberty, Gerard, Faelth-Savitski, Maria, Bantscheff, Marcus, Drewes, Gerard, Duraiswami, Chaya, Brady, Pat, Groy, Arthur, Narayanagari, Swathi-Rao, Antony-Debre, Ileana, Mitchell, Kelly, Wang, Heng Rui, Kao, Yun-Ruei, Christopeit, Maximilian, Carvajal, Luis, Barreyro, Laura, Paietta, Elisabeth, Makishima, Hideki, Will, Britta, Concha, Nestor, Adams, Nicholas D., Schwartz, Benjamin, McCabe, Michael T., Maciejewski, Jaroslav, Verma, Amit, Steidl, Ulrich

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Unbiased Detection of Posttranslational Modifications Using Mass Spectrometry von Savitski, Maria Fälth, Savitski, Mikhail M.

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DOT: A flexible multi-objective optimization framework for transferring features across single-cell and spatial omics von Rahimi, Arezou, Vale-Silva, Luis A, Savitski, Maria Faelth, Tanevski, Jovan, Saez-Rodriguez, Julio

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