Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity von Langer, Lukas M, Gat, Yair, Bonneau, Fabien, Conti, Elena

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Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8 von Langer, Lukas M, Bonneau, Fabien, Gat, Yair, Conti, Elena

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The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism von Kögel, Alexander, Keidel, Achim, Bonneau, Fabien, Schäfer, Ingmar B., Conti, Elena

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Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome von Gerlach, Piotr, Garland, William, Lingaraju, Mahesh, Salerno-Kochan, Anna, Bonneau, Fabien, Basquin, Jérôme, Jensen, Torben Heick, Conti, Elena

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The Yeast Exosome Functions as a Macromolecular Cage to Channel RNA Substrates for Degradation von Bonneau, Fabien, Basquin, Jérôme, Ebert, Judith, Lorentzen, Esben, Conti, Elena

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NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity von Le Hir, Hervé, Ballut, Lionel, Chamieh, Hala, Bonneau, Fabien

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Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4 von Benda, Christian, Ebert, Judith, Scheltema, Richard A., Schiller, Herbert B., Baumgärtner, Marc, Bonneau, Fabien, Mann, Matthias, Conti, Elena

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Sen1 has unique structural features grafted on the architecture of the Upf1‐like helicase family von Leonaitė, Bronislava, Han, Zhong, Basquin, Jérôme, Bonneau, Fabien, Libri, Domenico, Porrua, Odil, Conti, Elena

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Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and Its Regulation by Upf2 von Chakrabarti, Sutapa, Jayachandran, Uma, Bonneau, Fabien, Fiorini, Francesca, Basquin, Claire, Domcke, Silvia, Le Hir, Hervé, Conti, Elena

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Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase von Falk, Sebastian, Bonneau, Fabien, Ebert, Judith, Kögel, Alexander, Conti, Elena

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Structural analysis reveals the characteristic features of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance von Weir, John R., Bonneau, Fabien, Hentschel, Jendrik, Conti, Elena, Feigon, Juli

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The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities von Falk, Sebastian, Weir, John R., Hentschel, Jendrik, Reichelt, Peter, Bonneau, Fabien, Conti, Elena

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Distinct and evolutionary conserved structural features of the human nuclear exosome complex von Gerlach, Piotr, Schuller, Jan M, Bonneau, Fabien, Basquin, Jérôme, Reichelt, Peter, Falk, Sebastian, Conti, Elena

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Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex von Schuller, Sandra K, Schuller, Jan M, Prabu, J Rajan, Baumgärtner, Marc, Bonneau, Fabien, Basquin, Jérôme, Conti, Elena

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Structural basis for the activation of the C. elegans noncanonical cytoplasmic poly(A)-polymerase GLD-2 by GLD-3 von Nakel, Katharina, Fabien Bonneau, Christian R. Eckmann, Elena Conti

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The structure of the Pan2–Pan3 core complex reveals cross-talk between deadenylase and pseudokinase von Schäfer, Ingmar B, Rode, Michaela, Bonneau, Fabien, Schüssler, Steffen, Conti, Elena

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The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction von Pena, Vladimir, Hothorn, Michael, Eberth, Alexander, Kaschau, Nikolai, Parret, Annabel, Gremer, Lothar, Bonneau, Fabien, Ahmadian, Mohammad Reza, Scheffzek, Klaus

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A novel bipartite phospholipid-binding module in the neurofibromatosis type 1 protein von D'angelo, Igor, Welti, Stefan, Bonneau, Fabien, Scheffzek, Klaus

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InsP6 binding to PIKK kinases revealed by the cryo-EM structure of an SMG1–SMG8–SMG9 complex von Gat, Yair, Schuller, Jan Michael, Lingaraju, Mahesh, Weyher, Elisabeth, Bonneau, Fabien, Strauss, Mike, Murray, Peter J., Conti, Elena

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Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform von Nakel, Katharina, Hartung, Sophia A, Bonneau, Fabien, Eckmann, Christian R, Conti, Elena

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