Emerging patterns of somatic mutations in cancer von Watson, Ian R., Takahashi, Koichi, Futreal, P. Andrew, Chin, Lynda

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Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics von Morita, Kiyomi, Wang, Feng, Jahn, Katharina, Hu, Tianyuan, Tanaka, Tomoyuki, Sasaki, Yuya, Kuipers, Jack, Loghavi, Sanam, Wang, Sa A., Yan, Yuanqing, Furudate, Ken, Matthews, Jairo, Little, Latasha, Gumbs, Curtis, Zhang, Jianhua, Song, Xingzhi, Thompson, Erika, Patel, Keyur P., Bueso-Ramos, Carlos E., DiNardo, Courtney D., Ravandi, Farhad, Jabbour, Elias, Andreeff, Michael, Cortes, Jorge, Bhalla, Kapil, Garcia-Manero, Guillermo, Kantarjian, Hagop, Konopleva, Marina, Nakada, Daisuke, Navin, Nicholas, Beerenwinkel, Niko, Futreal, P. Andrew, Takahashi, Koichi

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Prediction of biomarkers and therapeutic combinations for anti-PD-1 immunotherapy using the global gene network association von Wu, Chia-Chin, Wang, Y. Alan, Livingston, J. Andrew, Zhang, Jianhua, Futreal, P. Andrew

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Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia von Wang, Feng, Morita, Kiyomi, DiNardo, Courtney D., Furudate, Ken, Tanaka, Tomoyuki, Yan, Yuanqing, Patel, Keyur P., MacBeth, Kyle J., Wu, Bin, Liu, Guowen, Frattini, Mark, Matthews, Jairo A., Little, Latasha D., Gumbs, Curtis, Song, Xingzhi, Zhang, Jianhua, Thompson, Erika J., Kadia, Tapan M., Garcia-Manero, Guillermo, Jabbour, Elias, Ravandi, Farhad, Bhalla, Kapil N., Konopleva, Marina, Kantarjian, Hagop M., Andrew Futreal, P., Takahashi, Koichi

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Cancer genomics: from discovery science to personalized medicine von Chin, Lynda, Andersen, Jannik N, Futreal, P Andrew

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing von Gerlinger, Marco, Rowan, Andrew J, Horswell, Stuart, Larkin, James, Endesfelder, David, Gronroos, Eva, Martinez, Pierre, Matthews, Nicholas, Stewart, Aengus, Tarpey, Patrick, Varela, Ignacio, Phillimore, Benjamin, Begum, Sharmin, McDonald, Neil Q, Butler, Adam, Jones, David, Raine, Keiran, Latimer, Calli, Santos, Claudio R, Nohadani, Mahrokh, Eklund, Aron C, Spencer-Dene, Bradley, Clark, Graham, Pickering, Lisa, Stamp, Gordon, Gore, Martin, Szallasi, Zoltan, Downward, Julian, Futreal, P. Andrew, Swanton, Charles

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Immuno-genomic landscape of osteosarcoma von Wu, Chia-Chin, Beird, Hannah C., Andrew Livingston, J., Advani, Shailesh, Mitra, Akash, Cao, Shaolong, Reuben, Alexandre, Ingram, Davis, Wang, Wei-Lien, Ju, Zhenlin, Hong Leung, Cheuk, Lin, Heather, Zheng, Youyun, Roszik, Jason, Wang, Wenyi, Patel, Shreyaskumar, Benjamin, Robert S., Somaiah, Neeta, Conley, Anthony P., Mills, Gordon B., Hwu, Patrick, Gorlick, Richard, Lazar, Alexander, Daw, Najat C., Lewis, Valerae, Futreal, P. Andrew

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Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing von Zhang, Jianjun, Fujimoto, Junya, Zhang, Jianhua, Wedge, David C., Song, Xingzhi, Zhang, Jiexin, Seth, Sahil, Chow, Chi-Wan, Cao, Yu, Gumbs, Curtis, Gold, Kathryn A., Kalhor, Neda, Little, Latasha, Mahadeshwar, Harshad, Moran, Cesar, Protopopov, Alexei, Sun, Huandong, Tang, Jiabin, Wu, Xifeng, Ye, Yuanqing, William, William N., Lee, J. Jack, Heymach, John V., Hong, Waun Ki, Swisher, Stephen, Wistuba, Ignacio I., Futreal, P. Andrew

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Preleukaemic clonal haemopoiesis and risk of therapy-related myeloid neoplasms: a case-control study von Takahashi, Koichi, MD, Wang, Feng, PhD, Kantarjian, Hagop, Prof, Doss, Denaha, MS, Khanna, Kanhav, MS, Thompson, Erika, MS, Zhao, Li, PhD, Patel, Keyur, MD, Neelapu, Sattva, MD, Gumbs, Curtis, BS, Bueso-Ramos, Carlos, Prof, DiNardo, Courtney D, MD, Colla, Simona, PhD, Ravandi, Farhad, Prof, Zhang, Jianhua, PhD, Huang, Xuelin, PhD, Wu, Xifeng, Prof, Samaniego, Felipe, MD, Garcia-Manero, Guillermo, Prof, Futreal, P Andrew, Prof

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Chromosomal Instability Confers Intrinsic Multidrug Resistance von LEE, Alvin J. X, ENDESFELDER, David, KSCHISCHO, Maik, SWANTON, Charles, ROWAN, Andrew J, WALTHER, Axel, BIRKBAK, Nicolai J, ANDREW FUTREAL, P, DOWNWARD, Julian, SZALLASI, Zoltan, TOMLINSON, Ian P. M, HOWELL, Michael

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Local mutational diversity drives intratumoral immune heterogeneity in non-small cell lung cancer von Jia, Qingzhu, Wu, Wei, Wang, Yuqi, Alexander, Peter B., Sun, Chengdu, Gong, Zhihua, Cheng, Jia-Nan, Sun, Huaibo, Guan, Yanfang, Xia, Xuefeng, Yang, Ling, Yi, Xin, Wan, Yisong Y., Wang, Haidong, He, Ji, Futreal, P. Andrew, Li, Qi-Jing, Zhu, Bo

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Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer von Yang, Jian, Gong, Yuhua, Lam, Vincent K., Shi, Yan, Guan, Yanfang, Zhang, Yanyan, Ji, Liyan, Chen, Yongsheng, Zhao, Yongliang, Qian, Feng, Chen, Jun, Li, Pingang, Zhang, Fan, Wang, Jiayin, Zhang, Xuanping, Yang, Ling, Kopetz, Scott, Futreal, P. Andrew, Zhang, Jianjun, Yi, Xin, Xia, Xuefeng, Yu, Peiwu

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Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing von Gerlinger, Marco, Horswell, Stuart, Larkin, James, Rowan, Andrew J, Salm, Max P, Varela, Ignacio, Fisher, Rosalie, McGranahan, Nicholas, Matthews, Nicholas, Santos, Claudio R, Martinez, Pierre, Phillimore, Benjamin, Begum, Sharmin, Rabinowitz, Adam, Spencer-Dene, Bradley, Gulati, Sakshi, Bates, Paul A, Stamp, Gordon, Pickering, Lisa, Gore, Martin, Nicol, David L, Hazell, Steven, Futreal, P Andrew, Stewart, Aengus, Swanton, Charles

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Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets von Ferrarotto, Renata, Mitani, Yoshitsugu, McGrail, Daniel J, Li, Kaiyi, Karpinets, Tatiana V, Bell, Diana, Frank, Steven J, Song, Xingzhi, Kupferman, Michael E, Liu, Bin, Lee, J Jack, Glisson, Bonnie S, Zhang, Jianhua, Aster, Jon C, Lin, Shiaw-Yih, Futreal, P Andrew, Heymach, John V, El-Naggar, Adel K

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Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure von Akdemir, Kadir C., Le, Victoria T., Kim, Justin M., Killcoyne, Sarah, King, Devin A., Lin, Ya-Ping, Tian, Yanyan, Inoue, Akira, Amin, Samirkumar B., Robinson, Frederick S., Nimmakayalu, Manjunath, Herrera, Rafael E., Lynn, Erica J., Chan, Kin, Seth, Sahil, Klimczak, Leszek J., Gerstung, Moritz, Gordenin, Dmitry A., O’Brien, John, Li, Lei, Deribe, Yonathan Lissanu, Verhaak, Roel G., Campbell, Peter J., Fitzgerald, Rebecca, Morrison, Ashby J., Dixon, Jesse R., Andrew Futreal, P.

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Comparative genomics of high grade neuroendocrine carcinoma of the cervix von Hillman, R Tyler, Cardnell, Robert, Fujimoto, Junya, Lee, Won-Chul, Zhang, Jianjun, Byers, Lauren A, Ramalingam, Preetha, Leitao, Mario, Swisher, Elizabeth, Futreal, P Andrew, Frumovitz, Michael

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MuSE: accounting for tumor heterogeneity using a sample-specific error model improves sensitivity and specificity in mutation calling from sequencing data von Fan, Yu, Xi, Liu, Hughes, Daniel S T, Zhang, Jianjun, Zhang, Jianhua, Futreal, P Andrew, Wheeler, David A, Wang, Wenyi

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PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy von Hsu, Joanne I., Dayaram, Tajhal, Tovy, Ayala, De Braekeleer, Etienne, Jeong, Mira, Wang, Feng, Zhang, Jianhua, Heffernan, Timothy P., Gera, Sonal, Kovacs, Jeffrey J., Marszalek, Joseph R., Bristow, Christopher, Yan, Yuanqing, Garcia-Manero, Guillermo, Kantarjian, Hagop, Vassiliou, George, Futreal, P. Andrew, Donehower, Lawrence A., Takahashi, Koichi, Goodell, Margaret A.

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Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells von Yang, Wanjuan, Soares, Jorge, Greninger, Patricia, Edelman, Elena J, Lightfoot, Howard, Forbes, Simon, Bindal, Nidhi, Beare, Dave, Smith, James A, Thompson, I Richard, Ramaswamy, Sridhar, Futreal, P Andrew, Haber, Daniel A, Stratton, Michael R, Benes, Cyril, McDermott, Ultan, Garnett, Mathew J

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A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia von Zeng, Andy G. X., Bansal, Suraj, Jin, Liqing, Mitchell, Amanda, Chen, Weihsu Claire, Abbas, Hussein A., Chan-Seng-Yue, Michelle, Voisin, Veronique, van Galen, Peter, Tierens, Anne, Cheok, Meyling, Preudhomme, Claude, Dombret, Hervé, Daver, Naval, Futreal, P. Andrew, Minden, Mark D., Kennedy, James A., Wang, Jean C. Y., Dick, John E.

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